Incidental Mutation 'IGL00948:Zfp764'
| ID |
27853 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp764
|
| Ensembl Gene |
ENSMUSG00000045757 |
| Gene Name |
zinc finger protein 764 |
| Synonyms |
8030466O12Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.061)
|
| Stock # |
IGL00948
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
127002840-127005994 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 127004376 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 252
(S252G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000052944
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000059199]
|
| AlphaFold |
E9QAP1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000059199
AA Change: S252G
PolyPhen 2
Score 0.927 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000052944
Gene: ENSMUSG00000045757
AA Change: S252G
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
22 |
82 |
7.33e-31 |
SMART |
|
low complexity region
|
102 |
115 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
152 |
174 |
4.47e-3 |
SMART |
|
ZnF_C2H2
|
180 |
202 |
1.47e-3 |
SMART |
|
ZnF_C2H2
|
208 |
230 |
4.3e-5 |
SMART |
|
ZnF_C2H2
|
236 |
258 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
264 |
286 |
1.47e-3 |
SMART |
|
ZnF_C2H2
|
292 |
315 |
1.45e-2 |
SMART |
|
ZnF_C2H2
|
321 |
343 |
6.52e-5 |
SMART |
|
ZnF_C2H2
|
349 |
371 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
377 |
399 |
1.67e-2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139118
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 25 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ccl2 |
A |
T |
11: 81,926,558 (GRCm39) |
Q24L |
possibly damaging |
Het |
| Cd33 |
G |
A |
7: 43,178,982 (GRCm39) |
|
probably benign |
Het |
| Cmya5 |
T |
C |
13: 93,227,544 (GRCm39) |
I2515V |
probably benign |
Het |
| Cntnap5b |
A |
G |
1: 100,069,082 (GRCm39) |
T101A |
probably benign |
Het |
| Cyp4a12a |
T |
A |
4: 115,159,159 (GRCm39) |
M143K |
probably damaging |
Het |
| Ephb4 |
C |
A |
5: 137,364,921 (GRCm39) |
S663R |
probably damaging |
Het |
| Gm4847 |
T |
C |
1: 166,457,907 (GRCm39) |
D482G |
probably benign |
Het |
| Gskip |
C |
A |
12: 105,665,103 (GRCm39) |
N47K |
probably damaging |
Het |
| Kmt2c |
T |
C |
5: 25,582,159 (GRCm39) |
Y473C |
probably benign |
Het |
| Lrrc7 |
T |
A |
3: 157,867,194 (GRCm39) |
N849I |
probably damaging |
Het |
| Magel2 |
T |
A |
7: 62,029,070 (GRCm39) |
V658E |
unknown |
Het |
| Nmral1 |
C |
T |
16: 4,534,270 (GRCm39) |
G57E |
probably damaging |
Het |
| Or6c211 |
A |
T |
10: 129,505,756 (GRCm39) |
L211I |
probably damaging |
Het |
| Or8b54 |
C |
T |
9: 38,687,108 (GRCm39) |
Q186* |
probably null |
Het |
| Padi3 |
C |
A |
4: 140,516,254 (GRCm39) |
R542L |
possibly damaging |
Het |
| Plrg1 |
T |
C |
3: 82,975,426 (GRCm39) |
V260A |
probably damaging |
Het |
| Prex2 |
A |
G |
1: 11,240,838 (GRCm39) |
H982R |
probably damaging |
Het |
| Rbm26 |
T |
A |
14: 105,387,779 (GRCm39) |
T448S |
probably damaging |
Het |
| Ryr1 |
C |
T |
7: 28,719,620 (GRCm39) |
M4262I |
possibly damaging |
Het |
| Slc41a3 |
A |
T |
6: 90,622,696 (GRCm39) |
D441V |
probably damaging |
Het |
| Slc7a2 |
A |
G |
8: 41,365,561 (GRCm39) |
E448G |
probably benign |
Het |
| Smtnl2 |
C |
A |
11: 72,302,067 (GRCm39) |
|
probably null |
Het |
| Tox3 |
G |
A |
8: 90,997,062 (GRCm39) |
P66L |
probably damaging |
Het |
| Vmn1r19 |
T |
C |
6: 57,382,247 (GRCm39) |
F267L |
probably benign |
Het |
| Vmn2r12 |
A |
G |
5: 109,245,541 (GRCm39) |
S64P |
possibly damaging |
Het |
|
| Other mutations in Zfp764 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
PIT4514001:Zfp764
|
UTSW |
7 |
127,003,913 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0528:Zfp764
|
UTSW |
7 |
127,004,051 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0619:Zfp764
|
UTSW |
7 |
127,005,713 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1183:Zfp764
|
UTSW |
7 |
127,005,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1770:Zfp764
|
UTSW |
7 |
127,004,739 (GRCm39) |
nonsense |
probably null |
|
|
R1878:Zfp764
|
UTSW |
7 |
127,004,214 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1885:Zfp764
|
UTSW |
7 |
127,004,211 (GRCm39) |
missense |
probably benign |
|
|
R2181:Zfp764
|
UTSW |
7 |
127,005,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4780:Zfp764
|
UTSW |
7 |
127,003,943 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5242:Zfp764
|
UTSW |
7 |
127,004,541 (GRCm39) |
missense |
probably benign |
|
|
R5493:Zfp764
|
UTSW |
7 |
127,004,105 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7109:Zfp764
|
UTSW |
7 |
127,003,887 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7214:Zfp764
|
UTSW |
7 |
127,004,450 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8047:Zfp764
|
UTSW |
7 |
127,005,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8748:Zfp764
|
UTSW |
7 |
127,003,862 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9131:Zfp764
|
UTSW |
7 |
127,005,719 (GRCm39) |
nonsense |
probably null |
|
|
R9187:Zfp764
|
UTSW |
7 |
127,004,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2013-04-17 |
Incidental Mutation