Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01881:Gm5862'

278990

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm5862

Ensembl Gene

ENSMUSG00000067700

Gene Name

predicted gene 5862

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.208) question?

Stock #

IGL01881

Quality Score

Status

Chromosome

Chromosomal Location

26223419-26227889 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 26227769 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Glycine at position 41 (W41G)

Ref Sequence

ENSEMBL: ENSMUSP00000072133 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000072286]

AlphaFold

K7N5V5

Predicted Effect

probably benign
Transcript: ENSMUST00000072286
AA Change: W41G

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000072133
Gene: ENSMUSG00000067700
AA Change: W41G

Domain	Start	End	E-Value	Type
Pfam:Takusan	50	134	1.6e-25	PFAM
low complexity region	154	168	N/A	INTRINSIC
low complexity region	235	259	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 13 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Asl	A	T	5: 130,047,379 (GRCm39)		probably benign	Het
Cd3g	A	T	9: 44,882,566 (GRCm39)	Y160N	probably damaging	Het
Exoc8	T	A	8: 125,623,090 (GRCm39)	R426W	probably damaging	Het
Fam216a	A	G	5: 122,505,698 (GRCm39)	Y114H	probably damaging	Het
Gm10718	A	T	9: 3,025,118 (GRCm39)	Y194F	probably benign	Het
Gm3402	A	T	5: 146,451,408 (GRCm39)	I89F	possibly damaging	Het
Mterf4	A	G	1: 93,232,363 (GRCm39)	S163P	probably damaging	Het
Myo7b	G	A	18: 32,133,320 (GRCm39)		probably benign	Het
Pde6b	A	T	5: 108,569,366 (GRCm39)	M358L	probably benign	Het
Ppp1cb	A	G	5: 32,635,487 (GRCm39)	I44V	probably benign	Het
Slitrk3	T	C	3: 72,956,639 (GRCm39)	E711G	probably benign	Het
Trappc9	A	T	15: 72,871,841 (GRCm39)	L492Q	probably damaging	Het
Tulp2	C	T	7: 45,170,219 (GRCm39)	R297W	probably damaging	Het

Other mutations in Gm5862

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01606:Gm5862	APN	5	26,224,514 (GRCm39)	missense	probably benign
IGL01863:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01868:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01873:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01902:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01905:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01909:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01917:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01924:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01927:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01951:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL03374:Gm5862	APN	5	26,224,510 (GRCm39)	missense	probably damaging	0.98
R2475:Gm5862	UTSW	5	26,224,490 (GRCm39)	missense	probably damaging	1.00
R3828:Gm5862	UTSW	5	26,224,345 (GRCm39)	missense	probably benign	0.27
R4591:Gm5862	UTSW	5	26,224,486 (GRCm39)	missense	possibly damaging	0.95
R6916:Gm5862	UTSW	5	26,224,346 (GRCm39)	missense	probably benign
R8291:Gm5862	UTSW	5	26,224,444 (GRCm39)	missense	probably benign	0.32
R8927:Gm5862	UTSW	5	26,226,678 (GRCm39)	missense	probably damaging	0.98
R8928:Gm5862	UTSW	5	26,226,678 (GRCm39)	missense	probably damaging	0.98
R9074:Gm5862	UTSW	5	26,226,624 (GRCm39)	missense	probably damaging	0.98
Z1176:Gm5862	UTSW	5	26,223,485 (GRCm39)	frame shift	probably null

Posted On

2015-04-16