Incidental Mutation 'IGL01917:Gm5862'
| ID |
279107 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Gm5862
|
| Ensembl Gene |
ENSMUSG00000067700 |
| Gene Name |
predicted gene 5862 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.208)
|
| Stock # |
IGL01917
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
5 |
| Chromosomal Location |
26223419-26227889 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 26227769 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tryptophan to Glycine
at position 41
(W41G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000072133
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072286]
|
| AlphaFold |
K7N5V5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000072286
AA Change: W41G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000072133
Gene: ENSMUSG00000067700
AA Change: W41G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Takusan
|
50 |
134 |
1.6e-25 |
PFAM |
|
low complexity region
|
154 |
168 |
N/A |
INTRINSIC |
|
low complexity region
|
235 |
259 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 23 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abt1 |
A |
T |
13: 23,607,959 (GRCm39) |
M15K |
unknown |
Het |
| Adal |
A |
G |
2: 120,973,035 (GRCm39) |
S31G |
possibly damaging |
Het |
| C2cd5 |
T |
C |
6: 143,018,322 (GRCm39) |
Y300C |
probably benign |
Het |
| Chia1 |
T |
A |
3: 106,035,536 (GRCm39) |
V184E |
probably damaging |
Het |
| Fat4 |
T |
A |
3: 38,943,879 (GRCm39) |
V924D |
possibly damaging |
Het |
| Fstl5 |
A |
T |
3: 76,615,153 (GRCm39) |
H738L |
probably damaging |
Het |
| Gimap4 |
T |
C |
6: 48,667,854 (GRCm39) |
M75T |
probably benign |
Het |
| Gm10238 |
A |
T |
15: 75,109,561 (GRCm39) |
|
noncoding transcript |
Het |
| Gm10718 |
A |
T |
9: 3,025,118 (GRCm39) |
Y194F |
probably benign |
Het |
| Gm21738 |
G |
A |
14: 19,416,979 (GRCm38) |
S144L |
probably benign |
Het |
| Gsdmc |
A |
G |
15: 63,650,434 (GRCm39) |
Y307H |
probably benign |
Het |
| Iqub |
A |
G |
6: 24,479,318 (GRCm39) |
L408P |
probably damaging |
Het |
| Lbx1 |
T |
A |
19: 45,222,652 (GRCm39) |
K124* |
probably null |
Het |
| Naip2 |
C |
A |
13: 100,298,591 (GRCm39) |
V482L |
probably benign |
Het |
| Or52e19 |
T |
A |
7: 102,959,564 (GRCm39) |
L212* |
probably null |
Het |
| Pdcd11 |
C |
A |
19: 47,089,604 (GRCm39) |
Q325K |
possibly damaging |
Het |
| Pik3c3 |
T |
A |
18: 30,407,499 (GRCm39) |
S82R |
probably damaging |
Het |
| Pramel11 |
T |
A |
4: 143,624,284 (GRCm39) |
E71V |
probably benign |
Het |
| Prickle1 |
T |
C |
15: 93,401,408 (GRCm39) |
K359E |
probably damaging |
Het |
| Ptprj |
A |
G |
2: 90,300,093 (GRCm39) |
V236A |
probably damaging |
Het |
| Serpinb3d |
T |
A |
1: 107,007,411 (GRCm39) |
T192S |
probably damaging |
Het |
| Usp31 |
T |
C |
7: 121,278,708 (GRCm39) |
N219S |
probably benign |
Het |
| Vmn2r129 |
C |
T |
4: 156,690,549 (GRCm39) |
|
noncoding transcript |
Het |
|
| Other mutations in Gm5862 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01606:Gm5862
|
APN |
5 |
26,224,514 (GRCm39) |
missense |
probably benign |
|
|
IGL01863:Gm5862
|
APN |
5 |
26,227,769 (GRCm39) |
missense |
probably benign |
|
|
IGL01868:Gm5862
|
APN |
5 |
26,227,769 (GRCm39) |
missense |
probably benign |
|
|
IGL01873:Gm5862
|
APN |
5 |
26,227,769 (GRCm39) |
missense |
probably benign |
|
|
IGL01881:Gm5862
|
APN |
5 |
26,227,769 (GRCm39) |
missense |
probably benign |
|
|
IGL01902:Gm5862
|
APN |
5 |
26,227,769 (GRCm39) |
missense |
probably benign |
|
|
IGL01905:Gm5862
|
APN |
5 |
26,227,769 (GRCm39) |
missense |
probably benign |
|
|
IGL01909:Gm5862
|
APN |
5 |
26,227,769 (GRCm39) |
missense |
probably benign |
|
|
IGL01924:Gm5862
|
APN |
5 |
26,227,769 (GRCm39) |
missense |
probably benign |
|
|
IGL01927:Gm5862
|
APN |
5 |
26,227,769 (GRCm39) |
missense |
probably benign |
|
|
IGL01951:Gm5862
|
APN |
5 |
26,227,769 (GRCm39) |
missense |
probably benign |
|
|
IGL03374:Gm5862
|
APN |
5 |
26,224,510 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2475:Gm5862
|
UTSW |
5 |
26,224,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3828:Gm5862
|
UTSW |
5 |
26,224,345 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4591:Gm5862
|
UTSW |
5 |
26,224,486 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6916:Gm5862
|
UTSW |
5 |
26,224,346 (GRCm39) |
missense |
probably benign |
|
|
R8291:Gm5862
|
UTSW |
5 |
26,224,444 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8927:Gm5862
|
UTSW |
5 |
26,226,678 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8928:Gm5862
|
UTSW |
5 |
26,226,678 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9074:Gm5862
|
UTSW |
5 |
26,226,624 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Gm5862
|
UTSW |
5 |
26,223,485 (GRCm39) |
frame shift |
probably null |
|
|
| Posted On |
2015-04-16 |
Incidental Mutation