Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00906:Erich1'

27993

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Erich1

Ensembl Gene

ENSMUSG00000051978

Gene Name

glutamate rich 1

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

IGL00906

Quality Score

Status

Chromosome

Chromosomal Location

14077561-14140301 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 14083770 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000147614 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000110813] [ENSMUST00000211242]

AlphaFold

E9PY43

Predicted Effect

probably benign
Transcript: ENSMUST00000110813

SMART Domains

Protein: ENSMUSP00000106436
Gene: ENSMUSG00000051978

Domain	Start	End	E-Value	Type
low complexity region	110	121	N/A	INTRINSIC
low complexity region	155	171	N/A	INTRINSIC
low complexity region	188	209	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000211242

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aacs	A	G	5: 125,580,338 (GRCm39)	E221G	probably benign	Het
Alb	A	G	5: 90,619,932 (GRCm39)	N453S	probably benign	Het
Bckdha	C	T	7: 25,332,767 (GRCm39)	V183M	probably benign	Het
Brpf3	A	G	17: 29,055,674 (GRCm39)		probably benign	Het
Ccdc163	T	C	4: 116,567,487 (GRCm39)		probably null	Het
Ccdc178	A	T	18: 22,268,225 (GRCm39)	C87*	probably null	Het
Cfhr4	A	T	1: 139,659,312 (GRCm39)	V739E	probably damaging	Het
Clca4a	A	G	3: 144,660,700 (GRCm39)	V708A	probably damaging	Het
Cyfip2	A	G	11: 46,091,512 (GRCm39)	V1136A	possibly damaging	Het
Dnah11	A	C	12: 117,874,937 (GRCm39)	L3976R	probably damaging	Het
Fam228a	A	T	12: 4,782,773 (GRCm39)	Y107N	possibly damaging	Het
Iars2	A	T	1: 185,028,600 (GRCm39)		probably benign	Het
Ifi204	A	G	1: 173,587,197 (GRCm39)		probably benign	Het
Ifih1	A	T	2: 62,476,168 (GRCm39)	I36N	probably benign	Het
Jak1	C	T	4: 101,011,826 (GRCm39)	G1092D	probably damaging	Het
Kir3dl2	G	A	X: 135,357,097 (GRCm39)	P122S	probably damaging	Het
Nacc2	T	C	2: 25,951,678 (GRCm39)	T386A	probably damaging	Het
Nrf1	C	T	6: 30,098,477 (GRCm39)	T135M	probably damaging	Het
Or4k15	A	G	14: 50,364,214 (GRCm39)	Y60C	probably damaging	Het
Or51i2	G	A	7: 103,689,051 (GRCm39)	G16D	probably damaging	Het
Pcca	A	C	14: 122,927,545 (GRCm39)	D436A	probably benign	Het
Pcdhb11	A	T	18: 37,555,174 (GRCm39)	Q168L	possibly damaging	Het
Pdgfra	A	G	5: 75,340,834 (GRCm39)	I598V	probably benign	Het
Pla2g6	C	T	15: 79,171,947 (GRCm39)	V637I	probably damaging	Het
Plac1	A	C	X: 52,159,593 (GRCm39)	V39G	probably damaging	Het
Pparg	A	G	6: 115,416,822 (GRCm39)	E5G	probably damaging	Het
Ppp1r9a	A	G	6: 5,157,023 (GRCm39)	D967G	possibly damaging	Het
Rel	T	C	11: 23,694,266 (GRCm39)	T322A	probably benign	Het
Sgk3	A	G	1: 9,947,470 (GRCm39)	T137A	probably benign	Het
Sgpp2	A	G	1: 78,367,184 (GRCm39)	R106G	probably benign	Het
Slc27a5	T	A	7: 12,724,984 (GRCm39)	M459L	probably benign	Het
Snx21	T	C	2: 164,628,140 (GRCm39)	L52P	probably damaging	Het
Srarp	G	A	4: 141,160,584 (GRCm39)	T83M	probably benign	Het
Sstr2	A	G	11: 113,515,821 (GRCm39)	R247G	probably benign	Het
Tnpo3	G	A	6: 29,589,047 (GRCm39)	S101L	probably damaging	Het
Zan	A	G	5: 137,387,622 (GRCm39)	I4863T	unknown	Het

Other mutations in Erich1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00927:Erich1	APN	8	14,083,518 (GRCm39)	missense	probably damaging	1.00
IGL01448:Erich1	APN	8	14,128,853 (GRCm39)	missense	possibly damaging	0.95
R1165:Erich1	UTSW	8	14,140,530 (GRCm39)	unclassified	probably benign
R1541:Erich1	UTSW	8	14,080,688 (GRCm39)	missense	probably damaging	0.97
R1699:Erich1	UTSW	8	14,140,259 (GRCm39)	missense	possibly damaging	0.73
R2094:Erich1	UTSW	8	14,140,527 (GRCm39)	unclassified	probably benign
R2153:Erich1	UTSW	8	14,128,773 (GRCm39)	missense	probably benign	0.08
R3807:Erich1	UTSW	8	14,083,695 (GRCm39)	missense	probably benign	0.11
R5787:Erich1	UTSW	8	14,083,776 (GRCm39)	splice site	probably null
R6119:Erich1	UTSW	8	14,083,692 (GRCm39)	missense	probably benign
R7034:Erich1	UTSW	8	14,114,330 (GRCm39)	missense	probably benign	0.02
R7363:Erich1	UTSW	8	14,083,688 (GRCm39)	missense	probably benign	0.05
R7687:Erich1	UTSW	8	14,080,691 (GRCm39)	missense	probably damaging	0.99
R9087:Erich1	UTSW	8	14,083,623 (GRCm39)	missense	probably damaging	0.99
R9376:Erich1	UTSW	8	14,080,719 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-04-17