Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02126:Vmn2r100'

280889

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r100

Ensembl Gene

ENSMUSG00000091859

Gene Name

vomeronasal 2, receptor 100

Synonyms

EG627537

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.073) question?

Stock #

IGL02126

Quality Score

Status

Chromosome

Chromosomal Location

19725073-19752322 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

T to C at 19741504 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000156263 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000166081] [ENSMUST00000231465]

AlphaFold

E9QAZ9

Predicted Effect

probably benign
Transcript: ENSMUST00000166081

SMART Domains

Protein: ENSMUSP00000128350
Gene: ENSMUSG00000091859

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
Pfam:ANF_receptor	83	456	7.4e-41	PFAM
Pfam:NCD3G	510	563	1.9e-21	PFAM
Pfam:7tm_3	594	831	2.6e-51	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000231465

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 51 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aldh16a1	G	A	7: 44,795,459 (GRCm39)	P400L	probably damaging	Het
Angptl3	T	C	4: 98,919,738 (GRCm39)		probably null	Het
Atoh1	T	C	6: 64,706,334 (GRCm39)	W10R	probably damaging	Het
Brd8	C	T	18: 34,735,780 (GRCm39)	S899N	probably damaging	Het
Ccm2	A	G	11: 6,544,154 (GRCm39)	T317A	probably damaging	Het
Ccnt1	A	T	15: 98,465,484 (GRCm39)	W12R	probably damaging	Het
Celf1	T	A	2: 90,831,408 (GRCm39)	L79H	probably damaging	Het
Cmip	T	C	8: 118,175,770 (GRCm39)	V423A	probably damaging	Het
Ddr1	T	A	17: 35,999,481 (GRCm39)	I431F	probably damaging	Het
Dnah6	A	G	6: 73,080,149 (GRCm39)	L2343P	probably benign	Het
Duox1	A	G	2: 122,176,817 (GRCm39)	D1446G	probably benign	Het
Erich3	A	G	3: 154,419,599 (GRCm39)	H231R	possibly damaging	Het
Fam221b	T	A	4: 43,666,450 (GRCm39)	I54F	probably benign	Het
Fcgbpl1	G	A	7: 27,839,281 (GRCm39)	V365M	probably damaging	Het
Galntl5	T	C	5: 25,394,839 (GRCm39)	F69L	possibly damaging	Het
Gba2	T	G	4: 43,567,918 (GRCm39)		probably null	Het
Gbf1	C	A	19: 46,240,556 (GRCm39)	P46Q	probably damaging	Het
Gimap6	T	G	6: 48,679,635 (GRCm39)	S134R	probably damaging	Het
Gm5424	A	C	10: 61,907,377 (GRCm39)		noncoding transcript	Het
Hexb	T	C	13: 97,314,532 (GRCm39)	K404E	possibly damaging	Het
Hs3st3a1	G	A	11: 64,327,331 (GRCm39)	V147M	probably damaging	Het
Hsd17b4	T	C	18: 50,315,063 (GRCm39)	V610A	probably benign	Het
Loxl3	T	A	6: 83,025,628 (GRCm39)	W329R	probably damaging	Het
Lrrc52	A	G	1: 167,273,575 (GRCm39)	F247S	probably damaging	Het
Naa38	C	T	11: 69,287,045 (GRCm39)	R42W	probably damaging	Het
Nadsyn1	G	A	7: 143,357,753 (GRCm39)	Q485*	probably null	Het
Nid1	A	G	13: 13,663,743 (GRCm39)		probably null	Het
Ofcc1	T	C	13: 40,362,251 (GRCm39)	T224A	probably benign	Het
Or5m11b	T	G	2: 85,806,517 (GRCm39)	I310S	probably benign	Het
Palld	A	G	8: 62,330,476 (GRCm39)	Y134H	possibly damaging	Het
Pfkfb4	C	T	9: 108,854,178 (GRCm39)	R351W	probably damaging	Het
Pfn3	T	C	13: 55,562,699 (GRCm39)	D94G	possibly damaging	Het
Pkhd1	G	A	1: 20,187,419 (GRCm39)	R3630C	probably damaging	Het
Por	T	A	5: 135,744,829 (GRCm39)	F31I	probably benign	Het
Ppp1r12c	T	C	7: 4,492,858 (GRCm39)	E127G	probably benign	Het
Ppp1r9a	T	A	6: 5,156,229 (GRCm39)	S1162T	probably damaging	Het
Psen2	C	A	1: 180,057,488 (GRCm39)	A297S	probably benign	Het
Rpusd2	G	A	2: 118,869,119 (GRCm39)	R514Q	probably damaging	Het
Rxrg	A	G	1: 167,462,029 (GRCm39)	M235V	probably damaging	Het
Sash1	T	C	10: 8,615,229 (GRCm39)	M644V	probably damaging	Het
Sf3b3	T	C	8: 111,550,075 (GRCm39)	T648A	probably benign	Het
Slco1a7	T	A	6: 141,684,739 (GRCm39)	T239S	probably benign	Het
Ssu72	T	C	4: 155,816,483 (GRCm39)	I155T	probably benign	Het
Tas2r102	A	G	6: 132,739,607 (GRCm39)	R172G	probably damaging	Het
Tmem214	G	A	5: 31,030,090 (GRCm39)	A296T	probably benign	Het
Trav12-2	C	A	14: 53,853,859 (GRCm39)	N2K	probably damaging	Het
Tyrp1	C	T	4: 80,755,845 (GRCm39)	Q205*	probably null	Het
Ubr4	T	A	4: 139,180,052 (GRCm39)		probably null	Het
Ush2a	A	G	1: 187,995,588 (GRCm39)	S120G	probably benign	Het
Zer1	G	T	2: 29,994,928 (GRCm39)	T489K	probably benign	Het
Zfp955b	G	T	17: 33,521,238 (GRCm39)	G236*	probably null	Het

Other mutations in Vmn2r100

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00904:Vmn2r100	APN	17	19,746,262 (GRCm39)	missense	probably damaging	1.00
IGL00912:Vmn2r100	APN	17	19,751,654 (GRCm39)	missense	possibly damaging	0.95
IGL01107:Vmn2r100	APN	17	19,741,618 (GRCm39)	missense	probably damaging	1.00
IGL01517:Vmn2r100	APN	17	19,742,225 (GRCm39)	missense	probably benign	0.37
IGL01594:Vmn2r100	APN	17	19,751,495 (GRCm39)	missense	possibly damaging	0.52
IGL01657:Vmn2r100	APN	17	19,746,178 (GRCm39)	missense	possibly damaging	0.89
IGL01822:Vmn2r100	APN	17	19,725,100 (GRCm39)	missense	probably null	0.00
IGL02020:Vmn2r100	APN	17	19,725,200 (GRCm39)	missense	possibly damaging	0.78
IGL02060:Vmn2r100	APN	17	19,741,516 (GRCm39)	missense	possibly damaging	0.79
IGL02142:Vmn2r100	APN	17	19,742,583 (GRCm39)	missense	probably damaging	1.00
IGL02308:Vmn2r100	APN	17	19,741,597 (GRCm39)	missense	possibly damaging	0.90
IGL02407:Vmn2r100	APN	17	19,741,770 (GRCm39)	missense	probably damaging	0.98
IGL02469:Vmn2r100	APN	17	19,751,547 (GRCm39)	nonsense	probably null
IGL03088:Vmn2r100	APN	17	19,742,301 (GRCm39)	missense	probably benign	0.27
IGL03181:Vmn2r100	APN	17	19,752,207 (GRCm39)	missense	probably damaging	1.00
IGL03405:Vmn2r100	APN	17	19,752,186 (GRCm39)	missense	probably damaging	1.00
H8562:Vmn2r100	UTSW	17	19,741,752 (GRCm39)	missense	possibly damaging	0.87
R0012:Vmn2r100	UTSW	17	19,746,296 (GRCm39)	missense	probably damaging	0.99
R0012:Vmn2r100	UTSW	17	19,725,136 (GRCm39)	missense	probably benign
R0044:Vmn2r100	UTSW	17	19,742,441 (GRCm39)	missense	possibly damaging	0.46
R0109:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0111:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0112:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0149:Vmn2r100	UTSW	17	19,741,509 (GRCm39)	critical splice acceptor site	probably null
R0355:Vmn2r100	UTSW	17	19,751,582 (GRCm39)	missense	probably benign	0.00
R0395:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0396:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0453:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0465:Vmn2r100	UTSW	17	19,751,792 (GRCm39)	missense	probably damaging	0.98
R0477:Vmn2r100	UTSW	17	19,742,776 (GRCm39)	missense	probably benign	0.00
R0510:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0512:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0514:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0518:Vmn2r100	UTSW	17	19,742,178 (GRCm39)	missense	probably damaging	1.00
R0521:Vmn2r100	UTSW	17	19,742,178 (GRCm39)	missense	probably damaging	1.00
R0555:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0608:Vmn2r100	UTSW	17	19,742,382 (GRCm39)	missense	possibly damaging	0.80
R0959:Vmn2r100	UTSW	17	19,743,786 (GRCm39)	missense	possibly damaging	0.95
R1114:Vmn2r100	UTSW	17	19,752,261 (GRCm39)	missense	probably damaging	1.00
R2027:Vmn2r100	UTSW	17	19,742,334 (GRCm39)	missense	probably benign	0.02
R2049:Vmn2r100	UTSW	17	19,742,312 (GRCm39)	missense	probably benign	0.00
R2224:Vmn2r100	UTSW	17	19,742,634 (GRCm39)	missense	probably benign	0.03
R2226:Vmn2r100	UTSW	17	19,742,634 (GRCm39)	missense	probably benign	0.03
R3618:Vmn2r100	UTSW	17	19,743,692 (GRCm39)	missense	probably benign
R3715:Vmn2r100	UTSW	17	19,752,272 (GRCm39)	missense	probably damaging	0.99
R4120:Vmn2r100	UTSW	17	19,752,215 (GRCm39)	missense	probably damaging	1.00
R4152:Vmn2r100	UTSW	17	19,743,681 (GRCm39)	frame shift	probably null
R4153:Vmn2r100	UTSW	17	19,743,681 (GRCm39)	frame shift	probably null
R4154:Vmn2r100	UTSW	17	19,743,681 (GRCm39)	frame shift	probably null
R4200:Vmn2r100	UTSW	17	19,742,797 (GRCm39)	missense	probably benign	0.29
R4632:Vmn2r100	UTSW	17	19,752,216 (GRCm39)	missense	probably damaging	1.00
R4720:Vmn2r100	UTSW	17	19,742,788 (GRCm39)	missense	probably benign	0.02
R4761:Vmn2r100	UTSW	17	19,741,630 (GRCm39)	missense	possibly damaging	0.47
R4831:Vmn2r100	UTSW	17	19,741,672 (GRCm39)	missense	probably benign	0.28
R4951:Vmn2r100	UTSW	17	19,752,300 (GRCm39)	missense	probably benign	0.01
R5211:Vmn2r100	UTSW	17	19,746,257 (GRCm39)	missense	possibly damaging	0.67
R5553:Vmn2r100	UTSW	17	19,725,110 (GRCm39)	missense	possibly damaging	0.64
R5657:Vmn2r100	UTSW	17	19,725,178 (GRCm39)	missense	probably benign	0.31
R5883:Vmn2r100	UTSW	17	19,743,786 (GRCm39)	missense	probably benign
R5912:Vmn2r100	UTSW	17	19,752,071 (GRCm39)	missense	probably damaging	0.99
R6141:Vmn2r100	UTSW	17	19,742,576 (GRCm39)	missense	probably benign	0.07
R6146:Vmn2r100	UTSW	17	19,742,522 (GRCm39)	missense	probably benign	0.04
R6500:Vmn2r100	UTSW	17	19,742,355 (GRCm39)	missense	probably damaging	1.00
R6575:Vmn2r100	UTSW	17	19,741,671 (GRCm39)	missense	probably benign	0.12
R6647:Vmn2r100	UTSW	17	19,742,785 (GRCm39)	missense	probably benign	0.00
R7038:Vmn2r100	UTSW	17	19,725,263 (GRCm39)	missense	possibly damaging	0.76
R7052:Vmn2r100	UTSW	17	19,751,556 (GRCm39)	missense	possibly damaging	0.95
R7170:Vmn2r100	UTSW	17	19,752,233 (GRCm39)	missense	probably benign	0.00
R7209:Vmn2r100	UTSW	17	19,751,576 (GRCm39)	missense	not run
R7312:Vmn2r100	UTSW	17	19,742,296 (GRCm39)	missense	probably benign	0.01
R7734:Vmn2r100	UTSW	17	19,742,296 (GRCm39)	missense	probably benign	0.01
R7750:Vmn2r100	UTSW	17	19,742,726 (GRCm39)	missense	probably benign
R8103:Vmn2r100	UTSW	17	19,751,415 (GRCm39)	splice site	probably null
R8193:Vmn2r100	UTSW	17	19,725,102 (GRCm39)	nonsense	probably null
R8267:Vmn2r100	UTSW	17	19,742,752 (GRCm39)	nonsense	probably null
R8290:Vmn2r100	UTSW	17	19,751,612 (GRCm39)	missense	probably damaging	0.99
R8531:Vmn2r100	UTSW	17	19,742,459 (GRCm39)	missense	possibly damaging	0.66
R8786:Vmn2r100	UTSW	17	19,742,838 (GRCm39)	missense	probably damaging	1.00
R8920:Vmn2r100	UTSW	17	19,741,620 (GRCm39)	missense	probably damaging	1.00
R8938:Vmn2r100	UTSW	17	19,751,825 (GRCm39)	missense	probably benign	0.00
R9555:Vmn2r100	UTSW	17	19,743,857 (GRCm39)	missense	probably benign	0.00
R9572:Vmn2r100	UTSW	17	19,741,513 (GRCm39)	missense	probably benign	0.00
R9609:Vmn2r100	UTSW	17	19,743,732 (GRCm39)	missense	probably damaging	1.00
R9618:Vmn2r100	UTSW	17	19,742,583 (GRCm39)	missense	probably damaging	1.00
X0062:Vmn2r100	UTSW	17	19,751,652 (GRCm39)	missense	possibly damaging	0.89
Z1176:Vmn2r100	UTSW	17	19,741,792 (GRCm39)	missense	probably benign	0.00
Z1177:Vmn2r100	UTSW	17	19,725,251 (GRCm39)	missense	probably benign	0.00

Posted On

2015-04-16