Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02096:Vmn2r43'

281138

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r43

Ensembl Gene

ENSMUSG00000053720

Gene Name

vomeronasal 2, receptor 43

Synonyms

EC2-V2R

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.103) question?

Stock #

IGL02096

Quality Score

Status

Chromosome

Chromosomal Location

8247347-8263598 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

G to A at 8260512 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000069647 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000066317]

AlphaFold

Q80Z08

Predicted Effect

probably benign
Transcript: ENSMUST00000066317

SMART Domains

Protein: ENSMUSP00000069647
Gene: ENSMUSG00000053720

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	453	5.1e-35	PFAM
Pfam:NCD3G	496	549	7.7e-21	PFAM
Pfam:7tm_3	582	817	3e-56	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 48 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca9	A	G	11: 109,993,359 (GRCm39)	L1584P	probably damaging	Het
Abca9	G	T	11: 110,056,806 (GRCm39)	H5N	probably benign	Het
Acox1	A	T	11: 116,069,024 (GRCm39)	I371N	probably damaging	Het
Aopep	C	A	13: 63,208,903 (GRCm39)	A340E	probably benign	Het
Bmp5	A	G	9: 75,805,833 (GRCm39)	N445S	probably damaging	Het
Cacna1b	G	T	2: 24,568,927 (GRCm39)	A999E	probably benign	Het
Cdc27	A	T	11: 104,419,394 (GRCm39)		probably benign	Het
Dmxl2	T	C	9: 54,308,349 (GRCm39)	E2134G	possibly damaging	Het
Dnttip2	A	G	3: 122,078,062 (GRCm39)	N698S	possibly damaging	Het
Duox1	A	T	2: 122,174,655 (GRCm39)	K1271M	probably damaging	Het
Dync1h1	T	C	12: 110,599,254 (GRCm39)	Y1870H	possibly damaging	Het
Edem3	A	G	1: 151,680,470 (GRCm39)	T532A	probably benign	Het
Epx	A	T	11: 87,760,294 (GRCm39)	L440Q	probably damaging	Het
F11	A	G	8: 45,699,791 (GRCm39)	F432L	probably benign	Het
Fam185a	C	A	5: 21,630,341 (GRCm39)	P59Q	probably damaging	Het
Fsip2	A	G	2: 82,822,204 (GRCm39)	D5979G	possibly damaging	Het
Furin	A	G	7: 80,043,207 (GRCm39)	S335P	probably damaging	Het
Gtf3c1	T	A	7: 125,258,284 (GRCm39)	Q1262L	probably damaging	Het
Hmmr	A	T	11: 40,598,256 (GRCm39)	V652E	probably benign	Het
Iapp	A	T	6: 142,249,199 (GRCm39)	N84I	probably benign	Het
Katnip	G	A	7: 125,413,993 (GRCm39)	C379Y	probably benign	Het
Mmp17	C	T	5: 129,675,752 (GRCm39)	Q304*	probably null	Het
Mpl	T	C	4: 118,314,333 (GRCm39)	T55A	possibly damaging	Het
Mst1r	G	A	9: 107,794,478 (GRCm39)	R1219H	probably damaging	Het
Muc6	T	A	7: 141,226,117 (GRCm39)		probably benign	Het
Nalcn	C	T	14: 123,831,915 (GRCm39)	V120I	probably benign	Het
Nt5dc1	A	T	10: 34,275,806 (GRCm39)	C134*	probably null	Het
Obscn	A	C	11: 58,971,530 (GRCm39)	N2228K	probably damaging	Het
Or2n1c	T	A	17: 38,520,074 (GRCm39)	*313R	probably null	Het
Osbpl10	T	C	9: 115,046,062 (GRCm39)	M566T	possibly damaging	Het
Pabpc1l	G	A	2: 163,886,267 (GRCm39)	V466I	probably benign	Het
Pdcd11	T	G	19: 47,094,860 (GRCm39)	V548G	probably benign	Het
Prss27	G	T	17: 24,263,951 (GRCm39)	K212N	possibly damaging	Het
Ranbp2	T	A	10: 58,297,789 (GRCm39)	S399T	probably damaging	Het
Rgs19	A	G	2: 181,331,076 (GRCm39)	S159P	probably damaging	Het
Sh2b1	A	G	7: 126,068,465 (GRCm39)	S449P	probably damaging	Het
Slc6a18	T	A	13: 73,820,870 (GRCm39)	Y238F	probably benign	Het
Stx11	T	C	10: 12,817,224 (GRCm39)	I167V	probably benign	Het
Sucnr1	A	G	3: 59,994,371 (GRCm39)	M300V	possibly damaging	Het
Synj2	A	G	17: 6,040,628 (GRCm39)	T235A	probably damaging	Het
Ubxn2b	T	A	4: 6,214,749 (GRCm39)	I261N	probably damaging	Het
Vmn2r45	A	G	7: 8,484,443 (GRCm39)	M454T	probably damaging	Het
Vsig2	T	A	9: 37,451,251 (GRCm39)	S51T	probably damaging	Het
Wdr41	T	C	13: 95,153,964 (GRCm39)		probably benign	Het
Wdr6	A	C	9: 108,453,752 (GRCm39)	L44V	probably damaging	Het
Zfp1001	T	C	2: 150,165,634 (GRCm39)	Y5H	probably damaging	Het
Zfp592	T	C	7: 80,674,796 (GRCm39)	Y587H	probably damaging	Het
Zfp735	A	T	11: 73,602,254 (GRCm39)	K399N	probably benign	Het

Other mutations in Vmn2r43

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01756:Vmn2r43	APN	7	8,258,583 (GRCm39)	missense	probably benign	0.00
IGL01777:Vmn2r43	APN	7	8,258,272 (GRCm39)	missense	probably damaging	1.00
IGL02429:Vmn2r43	APN	7	8,258,551 (GRCm39)	missense	probably benign	0.00
IGL03026:Vmn2r43	APN	7	8,258,096 (GRCm39)	missense	probably benign	0.05
IGL03155:Vmn2r43	APN	7	8,258,068 (GRCm39)	missense	possibly damaging	0.91
R1722:Vmn2r43	UTSW	7	8,258,067 (GRCm39)	missense	probably damaging	0.99
R1813:Vmn2r43	UTSW	7	8,258,055 (GRCm39)	missense	possibly damaging	0.81
R1896:Vmn2r43	UTSW	7	8,258,055 (GRCm39)	missense	possibly damaging	0.81
R1975:Vmn2r43	UTSW	7	8,258,550 (GRCm39)	missense	possibly damaging	0.91
R3951:Vmn2r43	UTSW	7	8,258,319 (GRCm39)	missense	probably benign	0.00
R4658:Vmn2r43	UTSW	7	8,258,070 (GRCm39)	missense	probably benign	0.01
R4879:Vmn2r43	UTSW	7	8,258,102 (GRCm39)	missense	probably benign	0.01
R4896:Vmn2r43	UTSW	7	8,247,848 (GRCm39)	missense	probably damaging	1.00
R5004:Vmn2r43	UTSW	7	8,247,848 (GRCm39)	missense	probably damaging	1.00
R5041:Vmn2r43	UTSW	7	8,247,806 (GRCm39)	missense	probably damaging	1.00
R5577:Vmn2r43	UTSW	7	8,247,811 (GRCm39)	missense	probably damaging	1.00
R6073:Vmn2r43	UTSW	7	8,258,184 (GRCm39)	missense	probably benign	0.13
R6133:Vmn2r43	UTSW	7	8,247,970 (GRCm39)	missense	probably damaging	1.00
R6867:Vmn2r43	UTSW	7	8,258,125 (GRCm39)	missense	probably benign	0.00
R7214:Vmn2r43	UTSW	7	8,256,379 (GRCm39)	critical splice donor site	probably null
R7339:Vmn2r43	UTSW	7	8,258,306 (GRCm39)	nonsense	probably null
R7424:Vmn2r43	UTSW	7	8,258,328 (GRCm39)	missense	probably damaging	0.99
R7534:Vmn2r43	UTSW	7	8,258,230 (GRCm39)	nonsense	probably null
R7542:Vmn2r43	UTSW	7	8,258,488 (GRCm39)	missense	probably benign	0.00
R7757:Vmn2r43	UTSW	7	8,258,253 (GRCm39)	missense	possibly damaging	0.77
R8131:Vmn2r43	UTSW	7	8,258,326 (GRCm39)	missense	probably benign	0.00
R8345:Vmn2r43	UTSW	7	8,256,601 (GRCm39)	missense	possibly damaging	0.69
R8418:Vmn2r43	UTSW	7	8,258,583 (GRCm39)	nonsense	probably null
R9691:Vmn2r43	UTSW	7	8,247,787 (GRCm39)	missense	probably damaging	1.00

Posted On

2015-04-16