Incidental Mutation 'IGL00903:Hacd3'
ID28127
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Hacd3
Ensembl Gene ENSMUSG00000033629
Gene Name3-hydroxyacyl-CoA dehydratase 3
SynonymsB-ind1, Hspc121, Ptplad1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.190) question?
Stock #IGL00903
Quality Score
Status
Chromosome9
Chromosomal Location64986983-65021693 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 65004253 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000044955 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000036615]
Predicted Effect probably benign
Transcript: ENSMUST00000036615
SMART Domains Protein: ENSMUSP00000044955
Gene: ENSMUSG00000033629

DomainStartEndE-ValueType
Pfam:CS 8 84 2.3e-7 PFAM
low complexity region 119 136 N/A INTRINSIC
transmembrane domain 153 175 N/A INTRINSIC
Pfam:PTPLA 195 356 1.5e-46 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1500012F01Rik G T 2: 167,065,486 probably benign Het
Arsk A G 13: 76,098,368 probably null Het
As3mt A G 19: 46,712,234 I159V probably benign Het
Ctsll3 C A 13: 60,800,261 V201L probably benign Het
Dapk1 T C 13: 60,761,397 Y1275H probably damaging Het
Erap1 G A 13: 74,673,707 R727H probably benign Het
Fam173b T C 15: 31,606,115 V73A possibly damaging Het
Fcrl6 T A 1: 172,599,107 T91S probably benign Het
Gvin1 T C 7: 106,158,170 E2364G probably benign Het
Hcls1 T A 16: 36,956,021 probably null Het
Igf2r C T 17: 12,683,867 R2432H possibly damaging Het
Kif27 C A 13: 58,344,672 V218F possibly damaging Het
Klhl20 T C 1: 161,090,506 Y70C probably benign Het
Krt86 C T 15: 101,473,860 H104Y probably benign Het
Lcn12 G T 2: 25,493,320 N15K possibly damaging Het
Mrgpra1 T C 7: 47,335,578 M118V probably benign Het
Nacad G T 11: 6,600,632 T853K probably damaging Het
Nos3 A T 5: 24,369,862 Q293L probably damaging Het
Prkca C T 11: 107,983,974 V381M probably damaging Het
Ptcd3 A G 6: 71,907,844 F37S possibly damaging Het
Ptgs2 A G 1: 150,104,424 Y371C probably damaging Het
Pygl T C 12: 70,207,742 Y143C probably damaging Het
Samhd1 A G 2: 157,107,423 probably benign Het
Scube1 T A 15: 83,703,501 H89L probably damaging Het
Tmem59l G A 8: 70,485,665 probably benign Het
Vmn2r108 A G 17: 20,462,512 V810A probably damaging Het
Vmn2r61 T G 7: 42,300,511 F785C probably damaging Het
Other mutations in Hacd3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01323:Hacd3 APN 9 64998305 missense probably damaging 1.00
IGL02943:Hacd3 APN 9 64990436 missense probably damaging 0.99
R0145:Hacd3 UTSW 9 65004242 splice site probably benign
R0390:Hacd3 UTSW 9 65001022 missense possibly damaging 0.89
R2403:Hacd3 UTSW 9 65001029 missense probably damaging 1.00
R3117:Hacd3 UTSW 9 64998309 missense probably damaging 1.00
R3740:Hacd3 UTSW 9 65021473 missense possibly damaging 0.58
R4972:Hacd3 UTSW 9 64990436 missense probably damaging 0.99
R6174:Hacd3 UTSW 9 65005627 missense probably damaging 1.00
Posted On2013-04-17