Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02083:Jcad'

283444

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Jcad

Ensembl Gene

ENSMUSG00000033960

Gene Name

junctional cadherin 5 associated

Synonyms

9430020K01Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02083

Quality Score

Status

Chromosome

Chromosomal Location

4634878-4682869 bp(+) (GRCm39)

Type of Mutation

utr 3 prime

DNA Base Change (assembly)

G to T at 4680266 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000038613 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000037029]

AlphaFold

Q5DTX6

Predicted Effect

probably benign
Transcript: ENSMUST00000037029

SMART Domains

Protein: ENSMUSP00000038613
Gene: ENSMUSG00000033960

Domain	Start	End	E-Value	Type
Pfam:JCAD	1	1309	N/A	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acap1	A	C	11: 69,780,336 (GRCm39)	L36V	possibly damaging	Het
Aoc1l1	G	A	6: 48,953,194 (GRCm39)	G373D	probably damaging	Het
Atp13a3	T	C	16: 30,166,524 (GRCm39)	T540A	possibly damaging	Het
Bend5	A	C	4: 111,316,964 (GRCm39)	I376L	probably benign	Het
Ccdc138	T	C	10: 58,380,736 (GRCm39)		probably benign	Het
Cdh10	T	A	15: 18,986,975 (GRCm39)	I402N	possibly damaging	Het
Cfap44	T	C	16: 44,257,525 (GRCm39)	V1020A	probably damaging	Het
Chd2	A	T	7: 73,130,816 (GRCm39)	S749T	possibly damaging	Het
Enpp3	T	A	10: 24,652,692 (GRCm39)	D755V	probably damaging	Het
Fmo6	T	A	1: 162,748,033 (GRCm39)	K344*	probably null	Het
Gabbr1	A	G	17: 37,380,957 (GRCm39)	T767A	possibly damaging	Het
Gjd3	A	G	11: 98,873,587 (GRCm39)	S86P	probably damaging	Het
Grin1	A	G	2: 25,188,513 (GRCm39)	V432A	possibly damaging	Het
Igf2r	A	T	17: 12,912,079 (GRCm39)	C1849*	probably null	Het
Mrgpra4	A	T	7: 47,630,808 (GRCm39)	C264*	probably null	Het
Naa80	G	T	9: 107,460,798 (GRCm39)	R231L	probably benign	Het
Napepld	T	C	5: 21,881,065 (GRCm39)	Y110C	probably damaging	Het
Ncapd3	A	G	9: 26,963,117 (GRCm39)	E474G	probably damaging	Het
Pkhd1	T	A	1: 20,271,451 (GRCm39)	D3034V	probably damaging	Het
Plxnc1	T	C	10: 94,758,587 (GRCm39)	T370A	possibly damaging	Het
Ptger4	C	T	15: 5,272,655 (GRCm39)	R13H	probably benign	Het
Scg2	T	A	1: 79,413,941 (GRCm39)	T261S	probably benign	Het
Sfswap	T	C	5: 129,616,855 (GRCm39)	V433A	probably benign	Het
Sipa1l3	A	G	7: 29,086,686 (GRCm39)	Y635H	probably damaging	Het
Sp5	C	A	2: 70,306,758 (GRCm39)	P148T	possibly damaging	Het
Tlr5	A	G	1: 182,801,449 (GRCm39)	N251S	possibly damaging	Het
Tmem87a	A	T	2: 120,227,861 (GRCm39)	N95K	probably damaging	Het
Unc45b	C	T	11: 82,813,745 (GRCm39)	T384M	probably damaging	Het
Unc5c	T	C	3: 141,420,408 (GRCm39)	L117P	probably damaging	Het
Vcan	T	C	13: 89,873,684 (GRCm39)	N57D	probably damaging	Het
Zcchc8	G	T	5: 123,838,981 (GRCm39)	T519K	probably damaging	Het
Zfp729b	G	A	13: 67,743,349 (GRCm39)	T72I	probably benign	Het

Other mutations in Jcad

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00650:Jcad	APN	18	4,675,692 (GRCm39)	missense	probably benign	0.14
IGL00672:Jcad	APN	18	4,674,835 (GRCm39)	missense	possibly damaging	0.77
IGL00782:Jcad	APN	18	4,675,073 (GRCm39)	missense	probably benign	0.00
IGL00825:Jcad	APN	18	4,673,516 (GRCm39)	missense	probably damaging	1.00
IGL01522:Jcad	APN	18	4,673,312 (GRCm39)	missense	probably damaging	0.97
IGL01796:Jcad	APN	18	4,672,855 (GRCm39)	nonsense	probably null
IGL01973:Jcad	APN	18	4,675,514 (GRCm39)	missense	probably benign	0.21
IGL02625:Jcad	APN	18	4,674,422 (GRCm39)	missense	probably benign	0.03
IGL03002:Jcad	APN	18	4,675,153 (GRCm39)	missense	probably benign	0.00
IGL03325:Jcad	APN	18	4,673,902 (GRCm39)	missense	probably benign
R0304:Jcad	UTSW	18	4,673,325 (GRCm39)	missense	possibly damaging	0.75
R0487:Jcad	UTSW	18	4,673,243 (GRCm39)	missense	probably damaging	1.00
R0519:Jcad	UTSW	18	4,649,122 (GRCm39)	start gained	probably benign
R0664:Jcad	UTSW	18	4,676,063 (GRCm39)	missense	probably damaging	0.97
R1649:Jcad	UTSW	18	4,673,309 (GRCm39)	missense	probably damaging	1.00
R1710:Jcad	UTSW	18	4,674,511 (GRCm39)	missense	probably damaging	1.00
R1734:Jcad	UTSW	18	4,674,526 (GRCm39)	missense	probably damaging	1.00
R1823:Jcad	UTSW	18	4,675,780 (GRCm39)	missense	probably damaging	1.00
R1824:Jcad	UTSW	18	4,649,293 (GRCm39)	missense	probably benign
R1850:Jcad	UTSW	18	4,675,730 (GRCm39)	missense	possibly damaging	0.95
R1872:Jcad	UTSW	18	4,673,048 (GRCm39)	missense	probably benign
R1878:Jcad	UTSW	18	4,673,857 (GRCm39)	missense	possibly damaging	0.60
R1918:Jcad	UTSW	18	4,674,292 (GRCm39)	missense	probably damaging	1.00
R1967:Jcad	UTSW	18	4,675,162 (GRCm39)	missense	probably benign	0.07
R2420:Jcad	UTSW	18	4,675,952 (GRCm39)	missense	probably damaging	1.00
R2504:Jcad	UTSW	18	4,674,026 (GRCm39)	missense	probably damaging	0.99
R2936:Jcad	UTSW	18	4,675,153 (GRCm39)	missense	probably benign	0.00
R4420:Jcad	UTSW	18	4,676,032 (GRCm39)	missense	probably benign	0.00
R4668:Jcad	UTSW	18	4,680,221 (GRCm39)	splice site	probably null
R4670:Jcad	UTSW	18	4,674,175 (GRCm39)	missense	probably benign	0.03
R4671:Jcad	UTSW	18	4,674,175 (GRCm39)	missense	probably benign	0.03
R4707:Jcad	UTSW	18	4,649,338 (GRCm39)	nonsense	probably null
R4720:Jcad	UTSW	18	4,674,055 (GRCm39)	missense	probably benign	0.03
R4815:Jcad	UTSW	18	4,675,223 (GRCm39)	missense	possibly damaging	0.94
R4906:Jcad	UTSW	18	4,673,762 (GRCm39)	missense	probably damaging	1.00
R5214:Jcad	UTSW	18	4,674,134 (GRCm39)	missense	probably damaging	1.00
R5439:Jcad	UTSW	18	4,675,790 (GRCm39)	missense	probably damaging	1.00
R5563:Jcad	UTSW	18	4,673,944 (GRCm39)	missense	possibly damaging	0.93
R5721:Jcad	UTSW	18	4,676,044 (GRCm39)	missense	possibly damaging	0.48
R5825:Jcad	UTSW	18	4,674,896 (GRCm39)	missense	probably benign	0.00
R5952:Jcad	UTSW	18	4,674,554 (GRCm39)	missense	probably damaging	1.00
R6661:Jcad	UTSW	18	4,675,256 (GRCm39)	missense	probably damaging	1.00
R6928:Jcad	UTSW	18	4,673,372 (GRCm39)	missense	probably benign	0.00
R7426:Jcad	UTSW	18	4,675,529 (GRCm39)	missense	probably benign	0.11
R7808:Jcad	UTSW	18	4,673,113 (GRCm39)	missense	probably damaging	1.00
R7943:Jcad	UTSW	18	4,672,700 (GRCm39)	missense	probably damaging	1.00
R8010:Jcad	UTSW	18	4,674,581 (GRCm39)	missense	probably benign
R8080:Jcad	UTSW	18	4,649,270 (GRCm39)	missense	probably benign	0.01
R8133:Jcad	UTSW	18	4,649,384 (GRCm39)	missense	probably benign	0.03
R8168:Jcad	UTSW	18	4,675,094 (GRCm39)	missense	probably benign	0.00
R8232:Jcad	UTSW	18	4,674,862 (GRCm39)	missense	probably benign	0.23
R8276:Jcad	UTSW	18	4,674,318 (GRCm39)	missense	probably damaging	1.00
R8408:Jcad	UTSW	18	4,649,402 (GRCm39)	missense	possibly damaging	0.55
R9173:Jcad	UTSW	18	4,675,820 (GRCm39)	missense	probably benign	0.42
R9415:Jcad	UTSW	18	4,673,912 (GRCm39)	missense	probably damaging	1.00
R9571:Jcad	UTSW	18	4,673,252 (GRCm39)	nonsense	probably null
T0722:Jcad	UTSW	18	4,675,531 (GRCm39)	missense	probably benign	0.25
X0017:Jcad	UTSW	18	4,676,044 (GRCm39)	missense	probably benign	0.01

Posted On

2015-04-16