Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02191:Slc22a29'

283883

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Slc22a29

Ensembl Gene

ENSMUSG00000075044

Gene Name

solute carrier family 22. member 29

Synonyms

D630002G06Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02191

Quality Score

Status

Chromosome

Chromosomal Location

8137529-8196264 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

G to A at 8196045 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000152815 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000113298] [ENSMUST00000222533]

AlphaFold

Q8BWG6

Predicted Effect

probably benign
Transcript: ENSMUST00000113298

SMART Domains

Protein: ENSMUSP00000108923
Gene: ENSMUSG00000075044

Domain	Start	End	E-Value	Type
transmembrane domain	13	35	N/A	INTRINSIC
Pfam:Sugar_tr	99	528	1.3e-25	PFAM
Pfam:MFS_1	140	372	7.7e-14	PFAM
Pfam:MFS_1	348	549	6.5e-11	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000140910

SMART Domains

Protein: ENSMUSP00000117625
Gene: ENSMUSG00000075044

Domain	Start	End	E-Value	Type
transmembrane domain	13	35	N/A	INTRINSIC
Pfam:Sugar_tr	98	454	4.6e-20	PFAM
Pfam:MFS_1	137	462	3.6e-15	PFAM
low complexity region	467	481	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000149182

SMART Domains

Protein: ENSMUSP00000122262
Gene: ENSMUSG00000075044

Domain	Start	End	E-Value	Type
Pfam:Sugar_tr	62	418	2.2e-20	PFAM
Pfam:MFS_1	101	427	1.9e-15	PFAM
low complexity region	431	445	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000222533

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 30 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Actn1	T	C	12: 80,220,883 (GRCm39)	I642V	probably benign	Het
Adam5	G	A	8: 25,302,439 (GRCm39)	R185*	probably null	Het
C2	T	C	17: 35,085,539 (GRCm39)	I122V	probably damaging	Het
Camsap1	A	G	2: 25,819,892 (GRCm39)	I1531T	probably damaging	Het
Celsr1	T	C	15: 85,863,205 (GRCm39)	T1276A	possibly damaging	Het
Cnot7	A	T	8: 40,963,068 (GRCm39)	N35K	probably benign	Het
Cyp2a12	A	G	7: 26,736,036 (GRCm39)	I482V	probably benign	Het
Cyp3a57	A	G	5: 145,302,495 (GRCm39)	E97G	probably damaging	Het
Cyp51	C	A	5: 4,150,147 (GRCm39)	R192I	probably benign	Het
Ddx59	T	C	1: 136,344,896 (GRCm39)	L189P	probably damaging	Het
Dnah6	A	G	6: 72,994,780 (GRCm39)	I4127T	probably benign	Het
Dock3	C	T	9: 106,815,340 (GRCm39)	V1217I	probably benign	Het
Ergic2	T	C	6: 148,106,319 (GRCm39)	D57G	probably null	Het
Flvcr2	A	T	12: 85,832,966 (GRCm39)	K329*	probably null	Het
Foxp1	T	C	6: 98,922,561 (GRCm39)	S327G	probably damaging	Het
Gen1	A	C	12: 11,292,297 (GRCm39)	H562Q	probably benign	Het
Gjc2	A	G	11: 59,068,386 (GRCm39)	V32A	probably damaging	Het
Grk4	C	T	5: 34,912,533 (GRCm39)	H574Y	probably benign	Het
Kif15	T	A	9: 122,804,744 (GRCm39)	C93S	probably damaging	Het
Lrtm1	A	C	14: 28,743,906 (GRCm39)	I125L	probably benign	Het
Mrgprb8	A	G	7: 48,038,527 (GRCm39)	Y66C	probably damaging	Het
Pfn1	G	A	11: 70,545,209 (GRCm39)	A33V	probably damaging	Het
Scnn1b	A	C	7: 121,516,736 (GRCm39)	K492Q	probably damaging	Het
Spocd1	A	G	4: 129,847,380 (GRCm39)	D523G	probably damaging	Het
Tmem144	A	T	3: 79,734,159 (GRCm39)	D181E	possibly damaging	Het
Tmem220	G	A	11: 66,921,933 (GRCm39)	C101Y	probably damaging	Het
Tmpo	A	G	10: 90,997,741 (GRCm39)	V682A	probably benign	Het
Wdr93	A	G	7: 79,398,968 (GRCm39)	K34R	probably damaging	Het
Zdhhc16	C	A	19: 41,926,130 (GRCm39)	C8*	probably null	Het
Zfp318	C	T	17: 46,707,736 (GRCm39)	R265*	probably null	Het

Other mutations in Slc22a29

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00230:Slc22a29	APN	19	8,195,177 (GRCm39)	missense	probably benign	0.44
IGL00562:Slc22a29	APN	19	8,138,993 (GRCm39)	missense	probably benign	0.03
IGL00563:Slc22a29	APN	19	8,138,993 (GRCm39)	missense	probably benign	0.03
IGL00952:Slc22a29	APN	19	8,195,221 (GRCm39)	missense	probably damaging	1.00
IGL01526:Slc22a29	APN	19	8,184,542 (GRCm39)	splice site	probably benign
IGL01792:Slc22a29	APN	19	8,195,893 (GRCm39)	missense	probably damaging	1.00
IGL02391:Slc22a29	APN	19	8,146,717 (GRCm39)	missense	probably benign	0.13
IGL02408:Slc22a29	APN	19	8,184,649 (GRCm39)	missense	probably benign	0.00
IGL02957:Slc22a29	APN	19	8,147,354 (GRCm39)	missense	probably benign	0.01
IGL03059:Slc22a29	APN	19	8,147,354 (GRCm39)	missense	probably benign	0.01
IGL03299:Slc22a29	APN	19	8,140,012 (GRCm39)	critical splice donor site	probably null
IGL03368:Slc22a29	APN	19	8,184,626 (GRCm39)	critical splice donor site	probably null
R0017:Slc22a29	UTSW	19	8,195,630 (GRCm39)	splice site	probably benign
R0105:Slc22a29	UTSW	19	8,137,991 (GRCm39)	unclassified	probably benign
R0157:Slc22a29	UTSW	19	8,140,106 (GRCm39)	missense	possibly damaging	0.61
R0265:Slc22a29	UTSW	19	8,147,334 (GRCm39)	missense	probably benign	0.18
R1758:Slc22a29	UTSW	19	8,195,126 (GRCm39)	critical splice donor site	probably null
R1918:Slc22a29	UTSW	19	8,195,123 (GRCm39)	splice site	probably null
R1927:Slc22a29	UTSW	19	8,184,430 (GRCm39)	missense	probably benign	0.01
R1959:Slc22a29	UTSW	19	8,146,557 (GRCm39)	missense	probably benign	0.05
R1960:Slc22a29	UTSW	19	8,146,557 (GRCm39)	missense	probably benign	0.05
R1961:Slc22a29	UTSW	19	8,146,557 (GRCm39)	missense	probably benign	0.05
R1966:Slc22a29	UTSW	19	8,195,772 (GRCm39)	missense	probably damaging	1.00
R1968:Slc22a29	UTSW	19	8,195,707 (GRCm39)	missense	probably benign	0.27
R1997:Slc22a29	UTSW	19	8,195,162 (GRCm39)	missense	probably benign	0.00
R3105:Slc22a29	UTSW	19	8,147,337 (GRCm39)	missense	probably benign	0.25
R3725:Slc22a29	UTSW	19	8,195,973 (GRCm39)	missense	possibly damaging	0.78
R4118:Slc22a29	UTSW	19	8,137,893 (GRCm39)	unclassified	probably benign
R4465:Slc22a29	UTSW	19	8,140,088 (GRCm39)	nonsense	probably null
R4584:Slc22a29	UTSW	19	8,146,655 (GRCm39)	missense	probably benign	0.02
R4656:Slc22a29	UTSW	19	8,195,664 (GRCm39)	missense	possibly damaging	0.90
R4679:Slc22a29	UTSW	19	8,138,948 (GRCm39)	missense	possibly damaging	0.65
R4899:Slc22a29	UTSW	19	8,138,933 (GRCm39)	missense	probably benign	0.00
R4913:Slc22a29	UTSW	19	8,195,722 (GRCm39)	missense	probably benign	0.17
R5119:Slc22a29	UTSW	19	8,195,194 (GRCm39)	missense	probably damaging	0.99
R5470:Slc22a29	UTSW	19	8,138,880 (GRCm39)	missense	probably benign	0.01
R5474:Slc22a29	UTSW	19	8,195,221 (GRCm39)	missense	probably damaging	1.00
R6794:Slc22a29	UTSW	19	8,138,887 (GRCm39)	missense	probably benign	0.06
R6798:Slc22a29	UTSW	19	8,137,968 (GRCm39)	missense	probably benign	0.16
R7025:Slc22a29	UTSW	19	8,137,944 (GRCm39)	missense	probably benign
R7240:Slc22a29	UTSW	19	8,138,875 (GRCm39)	missense	probably damaging	0.98
R7535:Slc22a29	UTSW	19	8,147,342 (GRCm39)	missense	probably damaging	1.00
R7846:Slc22a29	UTSW	19	8,170,851 (GRCm39)	missense	probably benign	0.39
R8169:Slc22a29	UTSW	19	8,184,696 (GRCm39)	missense	probably damaging	1.00
R8275:Slc22a29	UTSW	19	8,146,681 (GRCm39)	missense	probably benign	0.00
R8403:Slc22a29	UTSW	19	8,139,004 (GRCm39)	missense	possibly damaging	0.95
R8872:Slc22a29	UTSW	19	8,137,931 (GRCm39)	missense	probably damaging	0.99
R9129:Slc22a29	UTSW	19	8,146,669 (GRCm39)	missense	probably benign	0.03
R9381:Slc22a29	UTSW	19	8,195,841 (GRCm39)	missense	probably benign	0.03
R9550:Slc22a29	UTSW	19	8,195,224 (GRCm39)	nonsense	probably null
R9645:Slc22a29	UTSW	19	8,184,488 (GRCm39)	missense	probably benign	0.04
R9673:Slc22a29	UTSW	19	8,140,104 (GRCm39)	missense	probably benign	0.00

Posted On

2015-04-16