Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02209:Mfsd1'

284647

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Mfsd1

Ensembl Gene

ENSMUSG00000027775

Gene Name

major facilitator superfamily domain containing 1

Synonyms

1200003O06Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02209

Quality Score

Status

Chromosome

Chromosomal Location

67490101-67511564 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 67505465 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000029344 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000029344]

AlphaFold

Q9DC37

Predicted Effect

probably benign
Transcript: ENSMUST00000029344

SMART Domains

Protein: ENSMUSP00000029344
Gene: ENSMUSG00000027775

Domain	Start	End	E-Value	Type
Pfam:MFS_1	45	404	2.3e-31	PFAM
Pfam:MFS_2	175	443	2.9e-9	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000192776

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcf1	C	T	17: 36,274,901 (GRCm39)	R82Q	probably damaging	Het
Acmsd	A	G	1: 127,687,492 (GRCm39)	Y258C	probably damaging	Het
Anapc5	A	G	5: 122,938,676 (GRCm39)	I366T	possibly damaging	Het
Crkl	C	T	16: 17,287,098 (GRCm39)	T218I	probably benign	Het
Egf	A	T	3: 129,500,956 (GRCm39)	I213K	possibly damaging	Het
Fry	A	G	5: 150,360,491 (GRCm39)	T33A	probably benign	Het
Garnl3	T	C	2: 32,975,942 (GRCm39)	D93G	probably damaging	Het
Hook3	C	T	8: 26,560,293 (GRCm39)	D311N	probably damaging	Het
Iglv3	T	C	16: 19,060,420 (GRCm39)	T4A	probably benign	Het
Kctd17	A	G	15: 78,319,792 (GRCm39)	N70S	probably damaging	Het
Kmt2d	T	C	15: 98,752,448 (GRCm39)		probably benign	Het
Lrif1	A	C	3: 106,639,045 (GRCm39)	L18F	probably damaging	Het
Msh4	A	G	3: 153,594,499 (GRCm39)	Y101H	probably damaging	Het
Mycbpap	G	A	11: 94,400,708 (GRCm39)		probably benign	Het
Myt1	A	G	2: 181,439,027 (GRCm39)	D183G	probably benign	Het
Nppc	T	C	1: 86,597,387 (GRCm39)	*127W	probably null	Het
Or10al3	G	A	17: 38,011,883 (GRCm39)	M107I	probably damaging	Het
Or1ak2	C	T	2: 36,827,517 (GRCm39)	P129S	probably damaging	Het
Or2n1e	A	G	17: 38,586,123 (GRCm39)	I154V	probably benign	Het
Or51i2	T	G	7: 103,689,663 (GRCm39)	L220R	probably damaging	Het
Or8b3b	T	C	9: 38,584,342 (GRCm39)	K146E	possibly damaging	Het
Pde5a	A	G	3: 122,618,664 (GRCm39)		probably benign	Het
Pkd1l3	T	C	8: 110,365,296 (GRCm39)	V1139A	probably damaging	Het
Pwwp2b	G	A	7: 138,835,021 (GRCm39)	R154Q	probably damaging	Het
Satb2	C	T	1: 56,910,677 (GRCm39)	V264I	probably damaging	Het
Slc6a2	T	A	8: 93,720,688 (GRCm39)	F435Y	probably benign	Het
Stmn2	T	C	3: 8,625,321 (GRCm39)		probably benign	Het
Synj1	A	G	16: 90,784,307 (GRCm39)	I277T	probably damaging	Het
Trio	C	T	15: 27,744,139 (GRCm39)	A2598T	probably damaging	Het
Tshz2	G	A	2: 169,726,684 (GRCm39)	V427M	probably damaging	Het
Utrn	A	G	10: 12,559,039 (GRCm39)	S1405P	probably damaging	Het
Vmn1r173	G	A	7: 23,402,586 (GRCm39)	V274I	probably benign	Het
Vmn2r116	T	C	17: 23,607,761 (GRCm39)	F443S	probably damaging	Het
Vps13d	C	A	4: 144,882,671 (GRCm39)	R974L	probably damaging	Het
Wapl	T	A	14: 34,399,218 (GRCm39)	S96T	possibly damaging	Het
Zfp516	A	G	18: 83,012,622 (GRCm39)	D1125G	probably benign	Het
Zfp692	C	T	11: 58,204,824 (GRCm39)	R395*	probably null	Het

Other mutations in Mfsd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01781:Mfsd1	APN	3	67,495,244 (GRCm39)	splice site	probably benign
IGL02186:Mfsd1	APN	3	67,503,928 (GRCm39)	missense	probably benign	0.00
IGL02293:Mfsd1	APN	3	67,505,425 (GRCm39)	missense	probably damaging	1.00
IGL03132:Mfsd1	APN	3	67,495,273 (GRCm39)	missense	possibly damaging	0.53
edelweiss	UTSW	3	67,503,936 (GRCm39)	nonsense	probably null
Schneeweiss	UTSW	3	67,492,995 (GRCm39)	missense	possibly damaging	0.79
white	UTSW	3	67,497,162 (GRCm39)	critical splice acceptor site	probably null
R0948:Mfsd1	UTSW	3	67,504,067 (GRCm39)	missense	possibly damaging	0.61
R2355:Mfsd1	UTSW	3	67,508,668 (GRCm39)	missense	probably damaging	1.00
R3407:Mfsd1	UTSW	3	67,504,046 (GRCm39)	missense	possibly damaging	0.70
R3408:Mfsd1	UTSW	3	67,504,046 (GRCm39)	missense	possibly damaging	0.70
R3729:Mfsd1	UTSW	3	67,490,298 (GRCm39)	missense	probably benign	0.03
R3749:Mfsd1	UTSW	3	67,490,286 (GRCm39)	missense	probably benign	0.09
R4405:Mfsd1	UTSW	3	67,507,943 (GRCm39)	missense	probably benign	0.07
R4867:Mfsd1	UTSW	3	67,495,320 (GRCm39)	critical splice donor site	probably null
R5429:Mfsd1	UTSW	3	67,507,293 (GRCm39)	missense	probably damaging	1.00
R5456:Mfsd1	UTSW	3	67,497,166 (GRCm39)	missense	probably benign	0.28
R5892:Mfsd1	UTSW	3	67,497,162 (GRCm39)	critical splice acceptor site	probably null
R6091:Mfsd1	UTSW	3	67,507,270 (GRCm39)	splice site	probably null
R6120:Mfsd1	UTSW	3	67,501,718 (GRCm39)	nonsense	probably null
R6671:Mfsd1	UTSW	3	67,492,995 (GRCm39)	missense	possibly damaging	0.79
R6752:Mfsd1	UTSW	3	67,503,936 (GRCm39)	nonsense	probably null
R6799:Mfsd1	UTSW	3	67,507,314 (GRCm39)	missense	probably damaging	0.97
R7117:Mfsd1	UTSW	3	67,507,391 (GRCm39)	splice site	probably null
R9748:Mfsd1	UTSW	3	67,499,910 (GRCm39)	missense	possibly damaging	0.52

Posted On

2015-04-16