Incidental Mutation 'IGL02225:Trbv20'
ID285327
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Trbv20
Ensembl Gene ENSMUSG00000076476
Gene NameT cell receptor beta, variable 20
SynonymsTcrb-V15, Gm16911
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.068) question?
Stock #IGL02225
Quality Score
Status
Chromosome6
Chromosomal Location41188273-41188977 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to A at 41188307 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000100093 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000103277]
Predicted Effect probably benign
Transcript: ENSMUST00000103277
SMART Domains Protein: ENSMUSP00000100093
Gene: ENSMUSG00000076476

DomainStartEndE-ValueType
Pfam:V-set 15 111 8e-11 PFAM
Pfam:I-set 17 111 1.8e-7 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acp4 A G 7: 44,256,741 probably null Het
Adgrf4 C A 17: 42,663,378 probably null Het
Aqp9 A T 9: 71,130,547 probably benign Het
C1s1 A G 6: 124,541,334 W8R probably benign Het
Cfap43 A G 19: 47,812,177 I345T probably benign Het
Cwh43 T C 5: 73,421,567 Y306H probably damaging Het
Cyp4a32 A T 4: 115,610,503 H228L probably benign Het
Ddx24 A G 12: 103,417,371 L607P probably damaging Het
Dlg3 A G X: 100,807,188 K232R probably benign Het
Fgfr1op T G 17: 8,182,419 D257E probably damaging Het
Fig4 A G 10: 41,256,452 S453P probably benign Het
Frem1 A G 4: 82,940,506 L1556P probably damaging Het
Gjb2 T C 14: 57,100,188 K188E probably damaging Het
Gp1bb C A 16: 18,620,900 W148L possibly damaging Het
Grip1 C T 10: 120,049,453 T375M probably damaging Het
Hnf1b T C 11: 83,861,785 L82P probably damaging Het
Jakmip1 T C 5: 37,104,856 V333A probably damaging Het
Magi1 G T 6: 93,694,026 R1069S probably damaging Het
Myh15 A T 16: 49,091,163 E319D probably benign Het
Myl4 A G 11: 104,580,402 I42V probably benign Het
Obsl1 A T 1: 75,503,798 V394E probably damaging Het
Olfr1137 C T 2: 87,711,399 C169Y possibly damaging Het
Olfr376 T A 11: 73,375,078 F110I probably damaging Het
Olfr598 A T 7: 103,329,166 I227F probably damaging Het
Pcnt C T 10: 76,389,474 R1732K probably benign Het
Pkd1l3 T C 8: 109,638,678 Y1144H probably damaging Het
Pogz A G 3: 94,879,016 K972E probably damaging Het
Sccpdh A G 1: 179,679,699 T227A probably benign Het
Sec16b A G 1: 157,532,044 probably benign Het
Slain2 T A 5: 72,941,390 V163E probably damaging Het
Snx1 G A 9: 66,109,621 P56L probably benign Het
Snx14 G A 9: 88,413,524 T196I probably damaging Het
Sspo T C 6: 48,484,334 F3570L probably benign Het
Tbrg4 C A 11: 6,624,094 V43F probably damaging Het
Traf3ip3 A G 1: 193,195,100 I176T probably benign Het
Ubc A T 5: 125,386,133 V710D probably benign Het
Ugt2b35 T C 5: 87,007,405 probably benign Het
Zbed5 C T 5: 129,902,133 probably null Het
Zc3hav1 T C 6: 38,340,341 Y108C probably damaging Het
Other mutations in Trbv20
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02451:Trbv20 APN 6 41188276 missense unknown
IGL03161:Trbv20 APN 6 41188823 missense probably benign 0.44
R4060:Trbv20 UTSW 6 41188261 unclassified probably benign
R5789:Trbv20 UTSW 6 41188791 missense probably damaging 1.00
R6245:Trbv20 UTSW 6 41188906 missense possibly damaging 0.87
R7556:Trbv20 UTSW 6 41188781 missense probably benign 0.10
Posted On2015-04-16