Incidental Mutation 'IGL02263:Vmn1r91'
| ID |
286806 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r91
|
| Ensembl Gene |
ENSMUSG00000095201 |
| Gene Name |
vomeronasal 1 receptor 91 |
| Synonyms |
Gm8442 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.175)
|
| Stock # |
IGL02263
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
19835083-19836006 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 19835768 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 229
(D229G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000129283
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000165330]
|
| AlphaFold |
E9PZR7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000165330
AA Change: D229G
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000129283
Gene: ENSMUSG00000095201
AA Change: D229G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
8 |
299 |
5.1e-18 |
PFAM |
|
Pfam:V1R
|
41 |
298 |
7.1e-15 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 25 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aff3 |
A |
G |
1: 38,574,680 (GRCm39) |
V100A |
probably damaging |
Het |
| Agmo |
T |
A |
12: 37,407,696 (GRCm39) |
N193K |
probably damaging |
Het |
| Dnah8 |
A |
G |
17: 30,948,139 (GRCm39) |
I1910V |
probably benign |
Het |
| Dsg2 |
T |
A |
18: 20,723,077 (GRCm39) |
S368T |
possibly damaging |
Het |
| Eif2ak4 |
A |
G |
2: 118,292,259 (GRCm39) |
T1270A |
probably benign |
Het |
| Ina |
T |
C |
19: 47,003,926 (GRCm39) |
S245P |
probably damaging |
Het |
| Katnb1 |
A |
G |
8: 95,816,703 (GRCm39) |
K96R |
probably damaging |
Het |
| Kcnj4 |
A |
G |
15: 79,369,988 (GRCm39) |
|
probably benign |
Het |
| Kcnn3 |
A |
G |
3: 89,568,525 (GRCm39) |
H601R |
possibly damaging |
Het |
| Lrrc25 |
C |
A |
8: 71,070,472 (GRCm39) |
F84L |
probably benign |
Het |
| Ltb |
A |
G |
17: 35,414,977 (GRCm39) |
Y259C |
probably damaging |
Het |
| Macc1 |
T |
G |
12: 119,409,752 (GRCm39) |
N173K |
possibly damaging |
Het |
| Med17 |
A |
T |
9: 15,178,772 (GRCm39) |
N466K |
probably damaging |
Het |
| Ncoa2 |
A |
T |
1: 13,244,987 (GRCm39) |
N570K |
probably damaging |
Het |
| Or52ae9 |
A |
T |
7: 103,390,262 (GRCm39) |
F62I |
probably damaging |
Het |
| Or5w1 |
A |
T |
2: 87,486,543 (GRCm39) |
C241S |
probably damaging |
Het |
| Or8k20 |
T |
A |
2: 86,106,546 (GRCm39) |
Y95F |
probably benign |
Het |
| Plb1 |
T |
C |
5: 32,478,692 (GRCm39) |
|
probably benign |
Het |
| Ptprk |
G |
A |
10: 27,951,110 (GRCm39) |
V12I |
unknown |
Het |
| Rabggta |
G |
A |
14: 55,956,418 (GRCm39) |
|
probably benign |
Het |
| Slc41a2 |
A |
G |
10: 83,149,364 (GRCm39) |
V193A |
possibly damaging |
Het |
| Thbs1 |
A |
G |
2: 117,950,361 (GRCm39) |
N665D |
probably benign |
Het |
| Tm9sf1 |
T |
C |
14: 55,880,392 (GRCm39) |
T2A |
possibly damaging |
Het |
| Traf7 |
C |
A |
17: 24,732,020 (GRCm39) |
C193F |
possibly damaging |
Het |
| Vmn2r7 |
A |
C |
3: 64,598,868 (GRCm39) |
V654G |
probably damaging |
Het |
|
| Other mutations in Vmn1r91 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01875:Vmn1r91
|
APN |
7 |
19,835,859 (GRCm39) |
nonsense |
probably null |
|
|
IGL02125:Vmn1r91
|
APN |
7 |
19,835,429 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02338:Vmn1r91
|
APN |
7 |
19,835,671 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02708:Vmn1r91
|
APN |
7 |
19,835,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1880:Vmn1r91
|
UTSW |
7 |
19,835,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2679:Vmn1r91
|
UTSW |
7 |
19,835,983 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4730:Vmn1r91
|
UTSW |
7 |
19,835,695 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5362:Vmn1r91
|
UTSW |
7 |
19,835,386 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5633:Vmn1r91
|
UTSW |
7 |
19,835,870 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R5979:Vmn1r91
|
UTSW |
7 |
19,835,990 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6151:Vmn1r91
|
UTSW |
7 |
19,835,360 (GRCm39) |
missense |
probably benign |
|
|
R6177:Vmn1r91
|
UTSW |
7 |
19,835,404 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7397:Vmn1r91
|
UTSW |
7 |
19,835,695 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7589:Vmn1r91
|
UTSW |
7 |
19,835,802 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7872:Vmn1r91
|
UTSW |
7 |
19,835,839 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7886:Vmn1r91
|
UTSW |
7 |
19,835,490 (GRCm39) |
missense |
probably benign |
|
|
R7903:Vmn1r91
|
UTSW |
7 |
19,835,135 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7953:Vmn1r91
|
UTSW |
7 |
19,835,218 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8043:Vmn1r91
|
UTSW |
7 |
19,835,218 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8202:Vmn1r91
|
UTSW |
7 |
19,835,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2015-04-16 |
Incidental Mutation