Incidental Mutation 'IGL02309:Ublcp1'
ID287761
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ublcp1
Ensembl Gene ENSMUSG00000041231
Gene Nameubiquitin-like domain containing CTD phosphatase 1
Synonyms4930527B16Rik, 8430435I17Rik
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.270) question?
Stock #IGL02309
Quality Score
Status
Chromosome11
Chromosomal Location44454571-44470498 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 44458328 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000099859 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000102795]
PDB Structure
Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein [SOLUTION NMR]
Predicted Effect probably benign
Transcript: ENSMUST00000102795
SMART Domains Protein: ENSMUSP00000099859
Gene: ENSMUSG00000041231

DomainStartEndE-ValueType
UBQ 3 77 8.74e-10 SMART
coiled coil region 101 128 N/A INTRINSIC
CPDc 136 278 3.02e-22 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000129054
Predicted Effect noncoding transcript
Transcript: ENSMUST00000136709
Predicted Effect noncoding transcript
Transcript: ENSMUST00000151875
Predicted Effect noncoding transcript
Transcript: ENSMUST00000156551
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 56 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcg4 A G 9: 44,281,828 F111S probably benign Het
Afg1l C A 10: 42,454,378 V98F possibly damaging Het
Agk T A 6: 40,376,276 D191E possibly damaging Het
Akap5 A G 12: 76,328,855 K354E possibly damaging Het
Aplp2 A T 9: 31,167,683 M323K possibly damaging Het
Arhgap23 T C 11: 97,466,001 probably benign Het
Asl A G 5: 130,019,781 Y30H probably damaging Het
Asxl3 T A 18: 22,522,453 H1173Q probably benign Het
Celsr2 C T 3: 108,396,011 R2472H probably damaging Het
Clip1 T A 5: 123,617,700 H950L probably damaging Het
Cx3cl1 A T 8: 94,780,032 T222S probably benign Het
Cyp4a14 T A 4: 115,491,632 N273Y probably damaging Het
Ddx52 T A 11: 83,948,478 S214T probably damaging Het
Dennd2d T A 3: 106,494,968 M318K probably benign Het
Dock3 A T 9: 106,913,152 D1E probably damaging Het
Farp1 C T 14: 121,243,516 T443I probably benign Het
Gm2381 C T 7: 42,822,609 probably benign Het
Gpr87 T A 3: 59,179,554 I178F possibly damaging Het
Grin2b C T 6: 135,736,472 E804K probably damaging Het
Gtf2h1 T C 7: 46,816,388 L421P probably damaging Het
Haghl T G 17: 25,784,664 H56P probably damaging Het
Heatr3 T C 8: 88,167,072 L489P probably damaging Het
Ighv6-6 A T 12: 114,434,914 H77Q probably benign Het
Kdm2b A G 5: 122,947,820 S243P probably damaging Het
Lamc3 T C 2: 31,914,604 probably benign Het
Lgr4 T C 2: 110,012,535 probably benign Het
Lhx3 T C 2: 26,201,373 Q308R probably benign Het
Lonp2 G A 8: 86,634,863 E223K probably damaging Het
Lta4h T C 10: 93,474,490 F407L probably damaging Het
Mndal C T 1: 173,874,455 G94R probably damaging Het
Nrxn3 A G 12: 89,976,407 N101S probably damaging Het
Olfr295 T C 7: 86,585,497 V74A possibly damaging Het
Olfr609 A T 7: 103,491,999 I293K probably damaging Het
Olfr912 C T 9: 38,581,513 P79S probably damaging Het
Olfr912 A G 9: 38,581,433 N52S probably damaging Het
Olfr930 A G 9: 38,931,052 N294D probably damaging Het
Pknox1 T G 17: 31,590,709 F96V probably benign Het
Psg25 T G 7: 18,526,424 Q183P probably damaging Het
Ptgs2 A G 1: 150,105,556 Y530C probably damaging Het
Sema3e T A 5: 14,224,390 D218E probably damaging Het
Shank1 G A 7: 44,312,842 G46R unknown Het
Sidt1 T C 16: 44,254,980 I672V probably benign Het
Slco1b2 T A 6: 141,672,281 S486T probably damaging Het
Smchd1 T C 17: 71,443,903 H340R probably benign Het
Smoc2 C A 17: 14,375,527 probably benign Het
Snapc1 A G 12: 73,968,027 Y102C probably damaging Het
Spo11 A G 2: 172,979,951 R20G probably damaging Het
Tlr1 A T 5: 64,925,947 L429* probably null Het
Tmem229b-ps T C 10: 53,475,370 noncoding transcript Het
Trim12c T A 7: 104,344,956 E230D possibly damaging Het
Ttc17 G T 2: 94,342,661 N796K probably benign Het
Ttc37 A G 13: 76,127,047 T238A possibly damaging Het
Ttn A G 2: 76,879,099 probably benign Het
Usf3 C T 16: 44,200,663 T11M probably benign Het
Vmn2r115 T A 17: 23,345,139 M95K probably benign Het
Wapl A G 14: 34,744,863 T1160A probably damaging Het
Other mutations in Ublcp1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00333:Ublcp1 APN 11 44460770 missense probably damaging 1.00
R0240:Ublcp1 UTSW 11 44458277 nonsense probably null
R0240:Ublcp1 UTSW 11 44458277 nonsense probably null
R2025:Ublcp1 UTSW 11 44465631 missense probably benign
R3809:Ublcp1 UTSW 11 44458282 missense probably benign 0.01
R5339:Ublcp1 UTSW 11 44455608 missense probably benign 0.00
R5656:Ublcp1 UTSW 11 44465606 missense probably damaging 0.99
Posted On2015-04-16