Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02311:Gm8237'

287821

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm8237

Ensembl Gene

ENSMUSG00000090707

Gene Name

predicted gene 8237

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL02311

Quality Score

Status

Chromosome

Chromosomal Location

16589391-16611855 bp(+) (GRCm39)

Type of Mutation

splice site (6 bp from exon)

DNA Base Change (assembly)

A to G at 5864425 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000127555 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000164484] [ENSMUST00000178594]

AlphaFold

E9Q257

Predicted Effect

probably null
Transcript: ENSMUST00000164484

SMART Domains

Protein: ENSMUSP00000127555
Gene: ENSMUSG00000090707

Domain	Start	End	E-Value	Type
Pfam:Takusan	48	128	6.5e-23	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000178594

SMART Domains

Protein: ENSMUSP00000136613
Gene: ENSMUSG00000090707

Domain	Start	End	E-Value	Type
Pfam:Takusan	1	74	4.5e-27	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1500035N22Rik	C	A	5: 25,202,705 (GRCm39)		probably benign	Het
Adam21	T	G	12: 81,607,666 (GRCm39)	D32A	probably benign	Het
Asns	A	G	6: 7,676,233 (GRCm39)		probably null	Het
Bin3	A	T	14: 70,361,666 (GRCm39)	M45L	probably benign	Het
Cfap44	A	T	16: 44,225,134 (GRCm39)		probably benign	Het
Cmya5	T	C	13: 93,227,163 (GRCm39)	T2642A	probably benign	Het
Dbndd2	T	C	2: 164,330,622 (GRCm39)	S92P	possibly damaging	Het
Dclre1b	A	C	3: 103,715,409 (GRCm39)	F30V	probably damaging	Het
Dock6	T	C	9: 21,755,624 (GRCm39)	D200G	probably damaging	Het
Epb41l4b	C	A	4: 57,076,456 (GRCm39)	R335L	probably damaging	Het
Fscn1	T	C	5: 142,957,765 (GRCm39)	V304A	probably benign	Het
Gm7008	G	A	12: 40,273,385 (GRCm39)		probably benign	Het
Ifih1	T	C	2: 62,440,847 (GRCm39)	T440A	probably damaging	Het
Mepe	C	T	5: 104,485,571 (GRCm39)	S237F	probably damaging	Het
Nr4a2	T	C	2: 57,001,743 (GRCm39)	I174V	probably benign	Het
Or2ag2	A	G	7: 106,485,101 (GRCm39)	Y308H	probably benign	Het
Or8c11	C	T	9: 38,289,194 (GRCm39)	Q6*	probably null	Het
Orc1	G	T	4: 108,457,171 (GRCm39)	V404L	probably benign	Het
Pcsk5	G	T	19: 17,410,784 (GRCm39)	Y1869*	probably null	Het
Phf21b	A	G	15: 84,678,095 (GRCm39)		probably null	Het
Pigg	A	G	5: 108,484,246 (GRCm39)	T631A	probably benign	Het
Plxnb1	A	G	9: 108,930,190 (GRCm39)	N349D	probably benign	Het
Scaf11	T	C	15: 96,316,637 (GRCm39)	S976G	probably benign	Het
Scn8a	G	T	15: 100,911,164 (GRCm39)	M861I	probably damaging	Het
Stau1	T	C	2: 166,792,239 (GRCm39)	N433S	probably damaging	Het
Synrg	A	G	11: 83,910,630 (GRCm39)	K854R	probably benign	Het
Tbata	T	A	10: 61,015,234 (GRCm39)	C150*	probably null	Het
Tcn2	G	A	11: 3,867,692 (GRCm39)	P417S	probably damaging	Het
Tlr1	A	T	5: 65,083,290 (GRCm39)	L429*	probably null	Het
Tpr	G	T	1: 150,274,404 (GRCm39)	D104Y	probably damaging	Het
Ubash3b	T	C	9: 40,958,333 (GRCm39)	T16A	probably benign	Het
Uso1	T	A	5: 92,335,635 (GRCm39)	S548T	probably benign	Het
Vps13b	T	A	15: 35,709,660 (GRCm39)	V1869E	probably benign	Het
Vps18	T	C	2: 119,120,732 (GRCm39)	C64R	probably benign	Het
Zic2	C	A	14: 122,713,606 (GRCm39)	N173K	probably damaging	Het

Other mutations in Gm8237

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00264:Gm8237	APN	14	5,864,475 (GRCm38)	missense	probably benign	0.01
IGL01380:Gm8237	APN	14	5,863,703 (GRCm38)	splice site	probably null
IGL02491:Gm8237	APN	14	5,863,577 (GRCm38)	nonsense	probably null
IGL03149:Gm8237	APN	14	5,864,451 (GRCm38)	missense	probably benign	0.00
R2520:Gm8237	UTSW	14	5,863,642 (GRCm38)	missense	possibly damaging	0.52
R8698:Gm8237	UTSW	14	5,863,554 (GRCm38)	missense	probably damaging	0.98
R8873:Gm8237	UTSW	14	5,862,453 (GRCm38)	nonsense	probably null
R9619:Gm8237	UTSW	14	5,863,637 (GRCm38)	missense	probably damaging	0.99

Posted On

2015-04-16