Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02313:Tex101'

287889

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tex101

Ensembl Gene

ENSMUSG00000062773

Gene Name

testis expressed gene 101

Synonyms

1700008H15Rik, TES101RP

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02313

Quality Score

Status

Chromosome

Chromosomal Location

24367437-24371475 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 24367750 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Methionine at position 201 (V201M)

Ref Sequence

ENSEMBL: ENSMUSP00000077150 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078001] [ENSMUST00000205488] [ENSMUST00000206390]

AlphaFold

Q9JMI7

Predicted Effect

probably damaging
Transcript: ENSMUST00000078001
AA Change: V201M

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000077150
Gene: ENSMUSG00000062773
AA Change: V201M

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
Pfam:UPAR_LY6	141	217	3.9e-15	PFAM
low complexity region	232	246	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000205488

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000206367

Predicted Effect

probably benign
Transcript: ENSMUST00000206390

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Male mice homozygous for a knockout allele of this marker are infertile due to the failure of sperm to migrate into the oviduct. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 55 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ankrd13c	T	A	3: 157,653,571 (GRCm39)	N136K	probably damaging	Het
Aph1b	A	T	9: 66,697,955 (GRCm39)		probably benign	Het
Atf7ip	A	G	6: 136,583,718 (GRCm39)	K1250E	probably damaging	Het
Atp8b2	T	C	3: 89,857,160 (GRCm39)	N400S	probably damaging	Het
Brca2	C	A	5: 150,462,126 (GRCm39)	S630Y	probably damaging	Het
Chd6	T	A	2: 160,807,595 (GRCm39)	E1873V	probably damaging	Het
Chrna10	T	C	7: 101,761,236 (GRCm39)		probably benign	Het
Col6a3	A	G	1: 90,739,328 (GRCm39)	L907P	probably damaging	Het
Cxcr6	A	G	9: 123,639,770 (GRCm39)	N264S	probably damaging	Het
Cyria	A	G	12: 12,414,752 (GRCm39)	T248A	possibly damaging	Het
Dgkg	A	G	16: 22,388,980 (GRCm39)		probably benign	Het
Dpysl2	T	G	14: 67,061,839 (GRCm39)	M256L	probably benign	Het
Dsp	G	T	13: 38,380,499 (GRCm39)	E1816*	probably null	Het
Fam13b	T	C	18: 34,587,709 (GRCm39)	K530E	probably damaging	Het
Fastk	T	C	5: 24,648,090 (GRCm39)	H242R	probably damaging	Het
Fbxw28	A	T	9: 109,166,420 (GRCm39)	H145Q	possibly damaging	Het
Heatr6	T	C	11: 83,669,718 (GRCm39)	L910P	probably damaging	Het
Hmcn2	A	G	2: 31,343,617 (GRCm39)	T4642A	possibly damaging	Het
Hspg2	A	G	4: 137,235,700 (GRCm39)	T167A	probably benign	Het
Igsf10	A	G	3: 59,238,111 (GRCm39)	L690P	probably benign	Het
Klhdc10	G	A	6: 30,439,865 (GRCm39)		probably null	Het
Krt31	A	G	11: 99,939,222 (GRCm39)	Y232H	probably damaging	Het
Lsm3	A	G	6: 91,493,070 (GRCm39)		probably benign	Het
Mfn2	T	A	4: 147,969,947 (GRCm39)	I375F	probably damaging	Het
Mfrp	A	T	9: 44,014,171 (GRCm39)	I180F	probably damaging	Het
Msh3	T	C	13: 92,485,820 (GRCm39)	E168G	possibly damaging	Het
Naa16	A	T	14: 79,622,108 (GRCm39)	V77D	probably damaging	Het
Nav2	T	C	7: 49,208,521 (GRCm39)	S1570P	probably damaging	Het
Niban3	A	G	8: 72,055,504 (GRCm39)	R305G	possibly damaging	Het
Numa1	C	T	7: 101,649,439 (GRCm39)	R1057*	probably null	Het
Nup210l	G	A	3: 90,030,099 (GRCm39)	A271T	probably damaging	Het
Ogdh	T	C	11: 6,305,400 (GRCm39)	V965A	probably damaging	Het
Or10h28	C	A	17: 33,488,639 (GRCm39)	Q314K	probably benign	Het
Or4m1	A	T	14: 50,557,473 (GRCm39)	V273E	probably damaging	Het
Or6c219	A	G	10: 129,781,772 (GRCm39)	L53P	probably damaging	Het
Or7g21	A	T	9: 19,032,671 (GRCm39)	N140I	probably damaging	Het
Or8b51	T	A	9: 38,569,362 (GRCm39)	I109F	probably damaging	Het
Pdp2	A	T	8: 105,321,531 (GRCm39)	Q460L	probably benign	Het
Pex5l	T	C	3: 33,047,141 (GRCm39)	T270A	probably benign	Het
Pkp4	C	T	2: 59,140,598 (GRCm39)	Q435*	probably null	Het
Prss32	G	A	17: 24,075,096 (GRCm39)	V149M	probably benign	Het
Riox2	C	A	16: 59,309,780 (GRCm39)	P378Q	probably benign	Het
Rita1	C	T	5: 120,747,858 (GRCm39)	A147T	probably damaging	Het
Rsph4a	T	A	10: 33,781,521 (GRCm39)	S124T	possibly damaging	Het
Sdccag8	G	A	1: 176,652,321 (GRCm39)	R24H	possibly damaging	Het
Slc22a1	C	A	17: 12,894,387 (GRCm39)	G54*	probably null	Het
Slc24a5	C	T	2: 124,927,567 (GRCm39)		probably benign	Het
Tmprss7	T	C	16: 45,501,956 (GRCm39)	Y223C	probably damaging	Het
Trpc4ap	T	C	2: 155,492,388 (GRCm39)	E382G	probably damaging	Het
Uggt1	A	T	1: 36,223,565 (GRCm39)	Y575N	probably damaging	Het
Vmn2r70	T	C	7: 85,214,376 (GRCm39)	I259V	probably damaging	Het
Xpo1	T	A	11: 23,227,065 (GRCm39)	N131K	probably damaging	Het
Zfp579	C	T	7: 4,997,432 (GRCm39)	V160M	probably benign	Het
Zfp697	A	G	3: 98,332,766 (GRCm39)	D64G	probably benign	Het
Zfp974	T	C	7: 27,611,678 (GRCm39)	T16A	possibly damaging	Het

Other mutations in Tex101

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL03007:Tex101	APN	7	24,369,906 (GRCm39)	splice site	probably benign
IGL03357:Tex101	APN	7	24,367,758 (GRCm39)	missense	probably damaging	0.96
R1935:Tex101	UTSW	7	24,367,650 (GRCm39)	missense	probably benign	0.33
R1936:Tex101	UTSW	7	24,367,650 (GRCm39)	missense	probably benign	0.33
R4632:Tex101	UTSW	7	24,367,793 (GRCm39)	nonsense	probably null
R6109:Tex101	UTSW	7	24,367,738 (GRCm39)	missense	possibly damaging	0.79
R7049:Tex101	UTSW	7	24,367,683 (GRCm39)	missense	probably benign	0.03
R7276:Tex101	UTSW	7	24,369,829 (GRCm39)	missense	probably damaging	1.00
R7860:Tex101	UTSW	7	24,369,190 (GRCm39)	missense	probably damaging	1.00
R8092:Tex101	UTSW	7	24,369,778 (GRCm39)	missense	probably damaging	1.00
R8435:Tex101	UTSW	7	24,367,791 (GRCm39)	missense	probably damaging	1.00
R8514:Tex101	UTSW	7	24,367,957 (GRCm39)	missense	possibly damaging	0.87

Posted On

2015-04-16