Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02324:Gm17093'

288391

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm17093

Ensembl Gene

ENSMUSG00000091429

Gene Name

predicted gene 17093

Synonyms

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.256) question?

Stock #

IGL02324

Quality Score

Status

Chromosome

Chromosomal Location

44755733-44760901 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 44755807 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 25 (T25A)

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000170427
AA Change: T25A

SMART Domains

Protein: ENSMUSP00000132075
Gene: ENSMUSG00000091429
AA Change: T25A

Domain	Start	End	E-Value	Type
Pfam:Takusan	57	137	2.6e-27	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227180

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrl4	T	A	3: 151,203,511 (GRCm39)	C124S	probably damaging	Het
Aldh1a7	T	C	19: 20,704,368 (GRCm39)	N42S	probably damaging	Het
Arhgef1	T	C	7: 24,623,240 (GRCm39)	L667P	probably damaging	Het
C1qb	C	A	4: 136,607,811 (GRCm39)	R184L	possibly damaging	Het
Cacna1s	A	G	1: 136,002,914 (GRCm39)		probably benign	Het
Cdk20	A	G	13: 64,585,734 (GRCm39)	E244G	probably benign	Het
Copg2	C	A	6: 30,840,469 (GRCm39)		probably null	Het
Cyp2d40	A	T	15: 82,645,149 (GRCm39)		probably benign	Het
Cyp2j6	A	G	4: 96,414,170 (GRCm39)	I365T	probably damaging	Het
Dhx29	A	G	13: 113,064,342 (GRCm39)	K6E	probably damaging	Het
Dpp10	T	A	1: 123,295,531 (GRCm39)	T539S	probably benign	Het
Ehbp1	A	T	11: 22,046,048 (GRCm39)	I542K	probably damaging	Het
Fat1	A	G	8: 45,493,593 (GRCm39)	Y3913C	probably damaging	Het
Flt4	C	T	11: 49,536,822 (GRCm39)	T1264I	probably benign	Het
Fmnl1	A	G	11: 103,070,364 (GRCm39)	D51G	probably damaging	Het
Gpatch2	A	G	1: 186,957,936 (GRCm39)	E97G	probably damaging	Het
Hcn1	T	C	13: 118,039,422 (GRCm39)	L446P	unknown	Het
Hpse2	A	T	19: 42,920,038 (GRCm39)	L354I	probably damaging	Het
Hspa4	A	G	11: 53,190,885 (GRCm39)		probably null	Het
Krtap16-1	C	T	11: 99,877,129 (GRCm39)	V92M	probably damaging	Het
Med23	A	T	10: 24,773,239 (GRCm39)	Q281L	probably damaging	Het
Megf8	T	C	7: 25,039,873 (GRCm39)	S963P	probably benign	Het
Mical1	G	A	10: 41,362,660 (GRCm39)	E932K	possibly damaging	Het
Mycbp2	A	G	14: 103,479,643 (GRCm39)	S1217P	probably damaging	Het
Myocd	C	A	11: 65,069,484 (GRCm39)	L785F	probably benign	Het
Nell2	T	C	15: 95,126,982 (GRCm39)	T798A	probably damaging	Het
Nfat5	T	C	8: 108,092,808 (GRCm39)		probably benign	Het
Olfm5	T	C	7: 103,803,302 (GRCm39)		probably null	Het
Or1e26	A	G	11: 73,480,081 (GRCm39)	V161A	probably benign	Het
P2ry1	A	T	3: 60,911,199 (GRCm39)	N113Y	possibly damaging	Het
Pan3	A	G	5: 147,466,933 (GRCm39)		probably null	Het
Pappa	A	G	4: 65,115,045 (GRCm39)	R714G	probably damaging	Het
Plcd1	A	G	9: 118,901,710 (GRCm39)	F579L	probably damaging	Het
Ptprb	T	C	10: 116,155,238 (GRCm39)	V664A	probably benign	Het
Slc27a5	T	A	7: 12,731,487 (GRCm39)	Q168L	probably benign	Het
Spag8	T	C	4: 43,651,781 (GRCm39)	E395G	probably damaging	Het
Stfa2l1	T	C	16: 35,982,138 (GRCm39)	Y70H	probably damaging	Het
Taf2	T	C	15: 54,891,772 (GRCm39)	N1017S	probably benign	Het
Tnfrsf25	C	A	4: 152,203,779 (GRCm39)	Q296K	probably damaging	Het
Trpm3	T	A	19: 22,676,143 (GRCm39)	I103N	probably benign	Het

Other mutations in Gm17093

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01401:Gm17093	APN	14	44,758,984 (GRCm39)	missense	unknown
IGL01431:Gm17093	APN	14	44,759,122 (GRCm39)	splice site	probably benign
IGL01911:Gm17093	APN	14	44,758,277 (GRCm39)	splice site	probably benign
IGL02418:Gm17093	APN	14	44,758,185 (GRCm39)	missense	unknown
IGL03072:Gm17093	APN	14	44,758,129 (GRCm39)	splice site	probably benign
R3419:Gm17093	UTSW	14	44,759,047 (GRCm39)	missense	unknown
R4838:Gm17093	UTSW	14	44,755,805 (GRCm39)	missense	unknown
R4994:Gm17093	UTSW	14	44,756,779 (GRCm39)	missense	probably damaging	1.00
R5819:Gm17093	UTSW	14	44,758,986 (GRCm39)	missense	unknown
R8167:Gm17093	UTSW	14	44,758,139 (GRCm39)	missense
R8962:Gm17093	UTSW	14	44,758,149 (GRCm39)	missense
R9757:Gm17093	UTSW	14	44,758,990 (GRCm39)	missense

Posted On

2015-04-16