Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02328:Scgb2b24'

288583

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Scgb2b24

Ensembl Gene

ENSMUSG00000046438

Gene Name

secretoglobin, family 2B, member 24

Synonyms

Abpz, Abpbg24, C2b, Scgb2b3

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.058) question?

Stock #

IGL02328

Quality Score

Status

Chromosome

Chromosomal Location

33436618-33438720 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 33438050 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000052456 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000055444]

AlphaFold

Q7M747

Predicted Effect

probably benign
Transcript: ENSMUST00000055444

SMART Domains

Protein: ENSMUSP00000052456
Gene: ENSMUSG00000046438

Domain	Start	End	E-Value	Type
low complexity region	5	11	N/A	INTRINSIC
Pfam:Feld-I_B	24	90	5.9e-33	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrv1	T	A	13: 81,726,294 (GRCm39)	N577I	probably damaging	Het
Arhgef1	T	C	7: 24,623,240 (GRCm39)	L667P	probably damaging	Het
Btk	G	A	X: 133,459,449 (GRCm39)	P192L	probably damaging	Het
Col12a1	T	A	9: 79,589,348 (GRCm39)	Y1069F	probably damaging	Het
Dnah7a	C	T	1: 53,564,096 (GRCm39)		probably null	Het
E230025N22Rik	A	G	18: 36,828,667 (GRCm39)	S4P	probably damaging	Het
Ei24	A	T	9: 36,696,827 (GRCm39)		probably null	Het
Foxred2	A	G	15: 77,840,032 (GRCm39)	L86P	probably damaging	Het
Gm3127	A	T	14: 15,424,989 (GRCm39)	R42W	probably damaging	Het
Hgf	A	G	5: 16,803,219 (GRCm39)	Y377C	probably damaging	Het
Hpse2	A	T	19: 42,920,038 (GRCm39)	L354I	probably damaging	Het
Hspa4	A	G	11: 53,190,885 (GRCm39)		probably null	Het
Iqcg	T	G	16: 32,839,876 (GRCm39)	I357L	probably benign	Het
Itsn1	T	C	16: 91,612,295 (GRCm39)	L204P	probably damaging	Het
Kalrn	T	C	16: 34,152,594 (GRCm39)	N311S	probably damaging	Het
Lmod2	A	G	6: 24,603,832 (GRCm39)	D269G	probably benign	Het
Med16	A	G	10: 79,743,376 (GRCm39)	S29P	probably damaging	Het
Mex3b	T	C	7: 82,518,920 (GRCm39)	S412P	probably benign	Het
Myo15a	A	G	11: 60,417,433 (GRCm39)	I3443V	probably benign	Het
Naip2	A	T	13: 100,297,877 (GRCm39)	L720I	probably damaging	Het
Or1e26	A	G	11: 73,480,081 (GRCm39)	V161A	probably benign	Het
Or4z4	T	A	19: 12,076,146 (GRCm39)	I286F	probably damaging	Het
Or52ab4	A	T	7: 102,987,497 (GRCm39)	I79F	probably damaging	Het
Or6c213	T	C	10: 129,573,895 (GRCm39)	D297G	probably benign	Het
Or8b1b	A	T	9: 38,375,972 (GRCm39)	I212F	probably benign	Het
Pan3	A	G	5: 147,466,933 (GRCm39)		probably null	Het
Pitpnm2	T	C	5: 124,259,477 (GRCm39)	Q1286R	probably damaging	Het
Sh2b3	T	C	5: 121,955,922 (GRCm39)	D520G	probably benign	Het
Skint4	T	A	4: 111,977,255 (GRCm39)	I215N	possibly damaging	Het
Slc24a5	A	G	2: 124,922,559 (GRCm39)	D107G	probably damaging	Het
Slit2	T	C	5: 48,387,646 (GRCm39)	I549T	probably damaging	Het
Stambp	A	G	6: 83,533,363 (GRCm39)	L300P	possibly damaging	Het
Taf2	T	C	15: 54,891,772 (GRCm39)	N1017S	probably benign	Het
Tm9sf2	T	G	14: 122,380,842 (GRCm39)	V145G	possibly damaging	Het
Tor1aip2	G	T	1: 155,940,720 (GRCm39)	C342F	probably damaging	Het
Ubr4	C	T	4: 139,206,233 (GRCm39)	T4823M	probably damaging	Het
Vmn1r80	G	T	7: 11,927,405 (GRCm39)	A172S	probably benign	Het
Vmn2r67	T	A	7: 84,799,898 (GRCm39)	N447Y	probably benign	Het
Zbtb1	A	G	12: 76,433,450 (GRCm39)	N479D	possibly damaging	Het

Other mutations in Scgb2b24

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01825:Scgb2b24	APN	7	33,438,652 (GRCm39)	missense	probably damaging	0.97
PIT4618001:Scgb2b24	UTSW	7	33,438,036 (GRCm39)	missense	probably damaging	0.96
R3441:Scgb2b24	UTSW	7	33,438,025 (GRCm39)	missense	probably damaging	1.00
R5874:Scgb2b24	UTSW	7	33,436,830 (GRCm39)	missense	probably damaging	0.99
R6572:Scgb2b24	UTSW	7	33,437,902 (GRCm39)	missense	probably damaging	1.00
R6800:Scgb2b24	UTSW	7	33,437,894 (GRCm39)	missense	probably benign	0.01
R7431:Scgb2b24	UTSW	7	33,438,674 (GRCm39)	missense	probably benign	0.13
R8096:Scgb2b24	UTSW	7	33,438,646 (GRCm39)	splice site	probably null
R8458:Scgb2b24	UTSW	7	33,436,779 (GRCm39)	missense	probably benign	0.00
R9481:Scgb2b24	UTSW	7	33,436,795 (GRCm39)	missense	probably benign	0.03

Posted On

2015-04-16