Incidental Mutation 'IGL02329:Trcg1'
| ID |
288609 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Trcg1
|
| Ensembl Gene |
ENSMUSG00000070298 |
| Gene Name |
taste receptor cell gene 1 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.070)
|
| Stock # |
IGL02329
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
9 |
| Chromosomal Location |
57143839-57157147 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 57147676 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 11
(I11F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091357
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000093837]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000093837
AA Change: I11F
PolyPhen 2
Score 0.915 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000091357
Gene: ENSMUSG00000070298
AA Change: I11F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
302 |
335 |
N/A |
INTRINSIC |
|
Blast:SEA
|
449 |
549 |
5e-21 |
BLAST |
|
low complexity region
|
580 |
594 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 32 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Atg2a |
T |
C |
19: 6,299,959 (GRCm39) |
|
probably null |
Het |
| Bfsp1 |
T |
C |
2: 143,704,566 (GRCm39) |
T96A |
probably benign |
Het |
| Btnl1 |
A |
G |
17: 34,601,239 (GRCm39) |
E322G |
possibly damaging |
Het |
| Cand2 |
T |
C |
6: 115,766,568 (GRCm39) |
V391A |
probably damaging |
Het |
| Ccdc169 |
A |
G |
3: 55,078,702 (GRCm39) |
M188V |
probably benign |
Het |
| Cngb1 |
T |
C |
8: 95,968,987 (GRCm39) |
I1174V |
probably benign |
Het |
| Cpeb4 |
T |
C |
11: 31,822,316 (GRCm39) |
V10A |
possibly damaging |
Het |
| Cpt1b |
T |
C |
15: 89,307,942 (GRCm39) |
T206A |
probably benign |
Het |
| Dapk3 |
T |
C |
10: 81,025,999 (GRCm39) |
S97P |
probably benign |
Het |
| Drc3 |
T |
C |
11: 60,261,404 (GRCm39) |
L185P |
probably damaging |
Het |
| Efr3b |
T |
C |
12: 4,042,923 (GRCm39) |
|
probably null |
Het |
| Erbb3 |
T |
A |
10: 128,409,088 (GRCm39) |
I742F |
probably damaging |
Het |
| Fktn |
A |
G |
4: 53,720,181 (GRCm39) |
Y65C |
probably benign |
Het |
| Fstl5 |
G |
A |
3: 76,496,302 (GRCm39) |
G355D |
probably damaging |
Het |
| Grm8 |
A |
T |
6: 27,363,115 (GRCm39) |
I800N |
probably damaging |
Het |
| Gss |
C |
T |
2: 155,409,773 (GRCm39) |
R221H |
probably benign |
Het |
| H2-M10.4 |
A |
T |
17: 36,771,359 (GRCm39) |
V273D |
probably damaging |
Het |
| Large1 |
C |
A |
8: 73,774,945 (GRCm39) |
W255L |
possibly damaging |
Het |
| Meig1 |
T |
C |
2: 3,410,288 (GRCm39) |
K71E |
probably damaging |
Het |
| Mtor |
A |
G |
4: 148,619,396 (GRCm39) |
N1760D |
probably benign |
Het |
| Ncapd2 |
A |
T |
6: 125,166,781 (GRCm39) |
N24K |
probably damaging |
Het |
| Nphp3 |
A |
C |
9: 103,903,167 (GRCm39) |
S715R |
probably benign |
Het |
| Papolg |
T |
G |
11: 23,841,869 (GRCm39) |
H18P |
probably damaging |
Het |
| Psd |
T |
C |
19: 46,308,098 (GRCm39) |
H667R |
possibly damaging |
Het |
| Rita1 |
C |
T |
5: 120,747,858 (GRCm39) |
A147T |
probably damaging |
Het |
| Rtp1 |
T |
C |
16: 23,249,943 (GRCm39) |
S103P |
probably damaging |
Het |
| Snx21 |
T |
C |
2: 164,634,310 (GRCm39) |
|
probably benign |
Het |
| Spmip3 |
A |
T |
1: 177,570,867 (GRCm39) |
Q67L |
probably benign |
Het |
| Tiam1 |
G |
T |
16: 89,596,924 (GRCm39) |
H301N |
probably benign |
Het |
| Trpm6 |
A |
G |
19: 18,831,581 (GRCm39) |
K1482R |
probably benign |
Het |
| Tyw1 |
G |
T |
5: 130,295,921 (GRCm39) |
G116V |
probably benign |
Het |
| Zfp341 |
T |
C |
2: 154,474,224 (GRCm39) |
C343R |
possibly damaging |
Het |
|
| Other mutations in Trcg1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01727:Trcg1
|
APN |
9 |
57,149,877 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01727:Trcg1
|
APN |
9 |
57,149,556 (GRCm39) |
missense |
probably benign |
|
|
IGL02147:Trcg1
|
APN |
9 |
57,153,132 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL02658:Trcg1
|
APN |
9 |
57,149,511 (GRCm39) |
nonsense |
probably null |
|
|
IGL02852:Trcg1
|
APN |
9 |
57,148,595 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03163:Trcg1
|
APN |
9 |
57,155,630 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
FR4589:Trcg1
|
UTSW |
9 |
57,149,485 (GRCm39) |
frame shift |
probably null |
|
|
R0555:Trcg1
|
UTSW |
9 |
57,149,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0747:Trcg1
|
UTSW |
9 |
57,149,204 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1061:Trcg1
|
UTSW |
9 |
57,153,156 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1521:Trcg1
|
UTSW |
9 |
57,149,748 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1622:Trcg1
|
UTSW |
9 |
57,155,955 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1652:Trcg1
|
UTSW |
9 |
57,152,856 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4677:Trcg1
|
UTSW |
9 |
57,153,144 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4879:Trcg1
|
UTSW |
9 |
57,154,003 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5013:Trcg1
|
UTSW |
9 |
57,149,562 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5141:Trcg1
|
UTSW |
9 |
57,148,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5690:Trcg1
|
UTSW |
9 |
57,149,094 (GRCm39) |
missense |
probably benign |
0.36 |
|
R6416:Trcg1
|
UTSW |
9 |
57,148,613 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6980:Trcg1
|
UTSW |
9 |
57,152,856 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7022:Trcg1
|
UTSW |
9 |
57,148,852 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7172:Trcg1
|
UTSW |
9 |
57,155,618 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7276:Trcg1
|
UTSW |
9 |
57,149,862 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7412:Trcg1
|
UTSW |
9 |
57,148,766 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7546:Trcg1
|
UTSW |
9 |
57,155,621 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7942:Trcg1
|
UTSW |
9 |
57,149,499 (GRCm39) |
missense |
probably benign |
|
|
R8087:Trcg1
|
UTSW |
9 |
57,155,957 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8094:Trcg1
|
UTSW |
9 |
57,149,564 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8825:Trcg1
|
UTSW |
9 |
57,148,754 (GRCm39) |
missense |
probably benign |
0.19 |
|
| Posted On |
2015-04-16 |
Incidental Mutation