Incidental Mutation 'IGL02348:Zswim7'
ID289369
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zswim7
Ensembl Gene ENSMUSG00000014243
Gene Namezinc finger SWIM-type containing 7
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.125) question?
Stock #IGL02348
Quality Score
Status
Chromosome11
Chromosomal Location62267224-62281375 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) G to T at 62268755 bp
ZygosityHeterozygous
Amino Acid Change Cysteine to Stop codon at position 85 (C85*)
Ref Sequence ENSEMBL: ENSMUSP00000072688 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000018644] [ENSMUST00000072916]
Predicted Effect probably benign
Transcript: ENSMUST00000018644
SMART Domains Protein: ENSMUSP00000018644
Gene: ENSMUSG00000018500

DomainStartEndE-ValueType
Pfam:7tm_4 15 308 1.1e-11 PFAM
Pfam:7TM_GPCR_Srsx 18 305 1.4e-13 PFAM
Pfam:7tm_1 24 290 3.8e-55 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000072916
AA Change: C85*
SMART Domains Protein: ENSMUSP00000072688
Gene: ENSMUSG00000014243
AA Change: C85*

DomainStartEndE-ValueType
Pfam:SWIM 66 114 1.7e-10 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4833423E24Rik T C 2: 85,493,296 I298V possibly damaging Het
Akap12 G A 10: 4,354,722 D511N probably damaging Het
Akt3 T A 1: 177,059,386 D299V probably damaging Het
Arfgef3 G A 10: 18,591,347 P2035L probably benign Het
Atp13a3 C T 16: 30,351,228 probably null Het
Capn9 C A 8: 124,594,677 P151T probably damaging Het
Csrnp1 T A 9: 119,972,643 D450V probably damaging Het
Ctrb1 C T 8: 111,687,130 A201T possibly damaging Het
Erp27 T C 6: 136,911,546 T145A probably damaging Het
Fanca A T 8: 123,305,263 L256Q probably damaging Het
Fars2 G A 13: 36,537,380 V433I probably benign Het
Fbxo9 T A 9: 78,109,007 M1L probably benign Het
Fcnb C A 2: 28,084,830 V10F possibly damaging Het
Gad2 C T 2: 22,629,393 H175Y probably damaging Het
Get4 G A 5: 139,252,499 G12D probably benign Het
Gmpr2 T A 14: 55,678,301 I312N probably damaging Het
Golm1 T A 13: 59,638,377 M334L probably benign Het
Itgam T A 7: 128,116,300 F1054L possibly damaging Het
Kcnk7 C A 19: 5,706,473 probably benign Het
Kif3b G A 2: 153,316,893 A205T probably damaging Het
Macf1 C T 4: 123,512,866 V276M probably damaging Het
Mdga2 T A 12: 66,550,575 N715I probably damaging Het
Mfap5 T A 6: 122,526,787 S103R possibly damaging Het
Nckap1 C T 2: 80,517,982 V876M probably damaging Het
Ncor1 A T 11: 62,333,659 probably benign Het
Nfya G A 17: 48,393,276 Q122* probably null Het
Nup210l G A 3: 90,104,164 probably benign Het
Olfr190 T G 16: 59,074,949 I44L probably damaging Het
Pcdhb19 T A 18: 37,498,808 L552Q probably damaging Het
Psmd2 T A 16: 20,654,647 S153T probably benign Het
Ptpn4 T C 1: 119,682,722 Y685C probably damaging Het
Rad54l2 T C 9: 106,720,376 R144G probably damaging Het
S1pr4 A C 10: 81,499,021 Y206* probably null Het
Slc39a14 A G 14: 70,316,436 probably null Het
Stx2 G A 5: 128,988,830 A254V probably damaging Het
Sumf2 G T 5: 129,859,870 G216C probably damaging Het
Tbc1d32 A G 10: 56,224,619 S88P probably benign Het
Trem1 T A 17: 48,232,796 M1K probably null Het
Trmt1l T C 1: 151,450,006 Y401H probably damaging Het
Ttc22 A T 4: 106,622,938 M130L probably damaging Het
Wnk1 T C 6: 119,963,328 E816G probably damaging Het
Wnt9b C T 11: 103,732,082 G165D probably damaging Het
Zscan21 A G 5: 138,133,383 T390A probably damaging Het
Other mutations in Zswim7
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0715:Zswim7 UTSW 11 62276647 unclassified probably benign
R2029:Zswim7 UTSW 11 62267473 unclassified probably benign
R3150:Zswim7 UTSW 11 62273785 missense possibly damaging 0.50
R5361:Zswim7 UTSW 11 62267547 missense probably benign 0.00
R6857:Zswim7 UTSW 11 62281129 unclassified probably benign
Posted On2015-04-16