Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02293:Eif1ad11'

290111

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Eif1ad11

Ensembl Gene

ENSMUSG00000095717

Gene Name

eukaryotic translation initiation factor 1A domain containing 11

Synonyms

Gm2056

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL02293

Quality Score

Status

Chromosome

Chromosomal Location

87993774-87994208 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 87994033 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Serine at position 87 (N87S)

Ref Sequence

ENSEMBL: ENSMUSP00000137563 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000178852]

AlphaFold

J3QQ02

Predicted Effect

probably benign
Transcript: ENSMUST00000178852
AA Change: N87S

PolyPhen 2 Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)

SMART Domains

Protein: ENSMUSP00000137563
Gene: ENSMUSG00000095717
AA Change: N87S

Domain	Start	End	E-Value	Type
low complexity region	3	25	N/A	INTRINSIC
eIF1a	28	110	5.09e-45	SMART
low complexity region	124	144	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000222496

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Agtr1a	A	G	13: 30,565,340 (GRCm39)	K135R	probably benign	Het
Ahdc1	C	T	4: 132,792,929 (GRCm39)	A1390V	possibly damaging	Het
Aldh1a2	A	G	9: 71,192,559 (GRCm39)		probably null	Het
Bltp2	T	A	11: 78,162,736 (GRCm39)	L866H	probably damaging	Het
C6	T	A	15: 4,784,785 (GRCm39)	I217K	probably benign	Het
Ccr1l1	G	A	9: 123,777,973 (GRCm39)	T158I	possibly damaging	Het
Dnah6	A	T	6: 73,110,633 (GRCm39)		probably benign	Het
Ect2l	A	G	10: 18,016,259 (GRCm39)		probably null	Het
Endov	T	C	11: 119,395,999 (GRCm39)		probably benign	Het
Fpr-rs7	A	G	17: 20,334,232 (GRCm39)	V86A	probably benign	Het
Gle1	A	G	2: 29,847,772 (GRCm39)	I660V	probably benign	Het
Hk2	A	T	6: 82,720,956 (GRCm39)	D159E	probably benign	Het
Hmcn1	A	G	1: 150,540,666 (GRCm39)	V2881A	probably damaging	Het
Hspa14	T	C	2: 3,512,071 (GRCm39)	K68E	probably damaging	Het
Ifi207	A	T	1: 173,551,314 (GRCm39)	I974N	probably damaging	Het
Igkv4-71	A	C	6: 69,220,306 (GRCm39)	S42A	possibly damaging	Het
Itgb4	G	A	11: 115,879,752 (GRCm39)	V635I	probably damaging	Het
Klhl32	A	G	4: 24,626,935 (GRCm39)	Y555H	probably damaging	Het
Lmbrd2	T	C	15: 9,172,276 (GRCm39)	S357P	probably benign	Het
Mfsd1	T	A	3: 67,505,425 (GRCm39)	V380D	probably damaging	Het
Ndc80	A	G	17: 71,821,273 (GRCm39)	F225S	probably damaging	Het
Or2ak7	T	C	11: 58,574,996 (GRCm39)	V99A	probably benign	Het
Or2n1	G	T	17: 38,486,577 (GRCm39)	V201L	probably benign	Het
Plxnd1	A	G	6: 115,940,874 (GRCm39)	V1355A	probably damaging	Het
Prkd1	A	G	12: 50,536,761 (GRCm39)	S108P	probably damaging	Het
Ptges3	C	T	10: 127,911,204 (GRCm39)		probably benign	Het
Rabggta	G	T	14: 55,959,153 (GRCm39)	L5M	probably benign	Het
Rag1	C	T	2: 101,473,391 (GRCm39)	D584N	probably benign	Het
Rasl12	A	G	9: 65,315,593 (GRCm39)	D79G	probably benign	Het
Rhoj	A	G	12: 75,422,186 (GRCm39)		probably benign	Het
Slc4a9	T	C	18: 36,666,268 (GRCm39)	L483P	probably benign	Het

Other mutations in Eif1ad11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R1652:Eif1ad11	UTSW	12	87,993,853 (GRCm39)	missense	probably benign	0.00
R4463:Eif1ad11	UTSW	12	87,994,129 (GRCm39)	missense	probably benign	0.06
R4820:Eif1ad11	UTSW	12	87,994,158 (GRCm39)	missense	unknown
R6575:Eif1ad11	UTSW	12	87,994,117 (GRCm39)	missense	probably damaging	0.97
R9152:Eif1ad11	UTSW	12	87,993,946 (GRCm39)	missense	probably damaging	1.00
R9165:Eif1ad11	UTSW	12	87,994,077 (GRCm39)	missense	possibly damaging	0.50

Posted On

2015-04-16