Incidental Mutation 'IGL02373:Vmn2r-ps130'
ID290989
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r-ps130
Ensembl Gene ENSMUSG00000095658
Gene Namevomeronasal 2, receptor, pseudogene 130
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.086) question?
Stock #IGL02373
Quality Score
Status
Chromosome17
Chromosomal Location23061367-23077425 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) A to T at 23076892 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Stop codon at position 679 (R679*)
Ref Sequence ENSEMBL: ENSMUSP00000135186 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000175853]
Predicted Effect probably null
Transcript: ENSMUST00000175853
AA Change: R679*
SMART Domains Protein: ENSMUSP00000135186
Gene: ENSMUSG00000095658
AA Change: R679*

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:ANF_receptor 76 469 5.4e-24 PFAM
Pfam:NCD3G 511 563 1.3e-21 PFAM
Pfam:7tm_3 594 831 2.1e-54 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adamtsl1 C T 4: 86,249,805 L462F probably damaging Het
Adgrv1 T C 13: 81,459,713 D4080G possibly damaging Het
Apc A C 18: 34,316,159 D2002A probably damaging Het
Apobr T A 7: 126,585,391 F25I probably damaging Het
Cyp4a10 T A 4: 115,521,077 L120* probably null Het
Daam2 A G 17: 49,473,380 S704P probably damaging Het
Dcst1 G T 3: 89,357,891 N217K probably damaging Het
Efr3b C T 12: 3,983,391 V139I probably benign Het
Fmn1 C A 2: 113,364,126 P57Q unknown Het
Galnt1 G A 18: 24,280,035 G464D possibly damaging Het
Ggcx T A 6: 72,427,919 W437R probably damaging Het
Gm11487 T C 4: 73,403,643 M52V probably benign Het
Igkv13-54-1 T C 6: 69,617,320 noncoding transcript Het
Iglon5 T C 7: 43,479,219 E58G probably benign Het
Met C T 6: 17,491,529 P97S probably damaging Het
Myg1 T A 15: 102,336,833 M158K probably damaging Het
Ncald T A 15: 37,372,209 M131L probably benign Het
Nipa2 T C 7: 55,933,128 I290V probably benign Het
Olfr1307 C A 2: 111,944,833 V208L probably benign Het
Olfr507 A T 7: 108,622,103 Y97F probably benign Het
Olfr818 A G 10: 129,945,465 L84S probably benign Het
Ppfia3 C T 7: 45,358,849 R48Q probably damaging Het
Rab12 A G 17: 66,498,065 L156P probably damaging Het
Slc28a3 C T 13: 58,578,404 probably null Het
Slc4a11 T C 2: 130,684,898 N770S probably benign Het
Tanc1 T C 2: 59,796,028 probably null Het
Vwa5b2 G A 16: 20,604,844 R1169H probably damaging Het
Other mutations in Vmn2r-ps130
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01929:Vmn2r-ps130 APN 17 23076877 missense possibly damaging 0.79
IGL02346:Vmn2r-ps130 APN 17 23061527 missense possibly damaging 0.89
R1511:Vmn2r-ps130 UTSW 17 23063801 missense probably benign 0.17
R2373:Vmn2r-ps130 UTSW 17 23061506 missense possibly damaging 0.93
R5047:Vmn2r-ps130 UTSW 17 23063820 missense probably benign
R5317:Vmn2r-ps130 UTSW 17 23063583 missense probably benign
R5588:Vmn2r-ps130 UTSW 17 23063829 missense probably benign 0.44
R5785:Vmn2r-ps130 UTSW 17 23061487 missense probably benign
R6131:Vmn2r-ps130 UTSW 17 23063655 missense probably benign 0.00
R6273:Vmn2r-ps130 UTSW 17 23076785 missense probably benign 0.12
R6580:Vmn2r-ps130 UTSW 17 23063766 missense probably benign 0.00
Posted On2015-04-16