Incidental Mutation 'IGL02388:Clec4b2'
ID291655
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Clec4b2
Ensembl Gene ENSMUSG00000067767
Gene NameC-type lectin domain family 4, member b2
SynonymsF830043G12Rik, mDCAR1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.051) question?
Stock #IGL02388
Quality Score
Status
Chromosome6
Chromosomal Location123172893-123204671 bp(+) (GRCm38)
Type of Mutationsplice site (3 bp from exon)
DNA Base Change (assembly) G to T at 123202228 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000085802 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000088455]
Predicted Effect probably null
Transcript: ENSMUST00000088455
SMART Domains Protein: ENSMUSP00000085802
Gene: ENSMUSG00000067767

DomainStartEndE-ValueType
transmembrane domain 21 43 N/A INTRINSIC
CLECT 79 202 1.87e-33 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 48 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930597O21Rik A T 6: 66,896,113 probably benign Het
9230019H11Rik A T 10: 3,125,050 noncoding transcript Het
Abca8a A G 11: 110,078,815 probably benign Het
Asphd1 A T 7: 126,946,712 probably benign Het
Ccdc77 G A 6: 120,331,897 A301V probably benign Het
Cep350 G T 1: 155,953,753 T135K probably benign Het
Chrna7 A T 7: 63,107,691 D153E probably damaging Het
Cyp2c67 T C 19: 39,643,355 N133D probably benign Het
Dglucy T C 12: 100,856,998 I484T probably damaging Het
Dtna G T 18: 23,597,514 M319I probably benign Het
E2f5 T A 3: 14,588,280 M152K probably benign Het
Emsy A T 7: 98,641,666 M58K probably damaging Het
Epha1 A G 6: 42,365,016 Y367H probably damaging Het
Etv1 A G 12: 38,781,799 S32G possibly damaging Het
Fam114a1 A T 5: 65,008,980 probably benign Het
Fbxo30 T A 10: 11,290,378 N281K probably benign Het
Galnt12 G T 4: 47,117,941 R412L probably damaging Het
Gm5786 T A 12: 59,081,596 noncoding transcript Het
Gm9845 T C 3: 39,358,467 noncoding transcript Het
Hecw2 A G 1: 53,925,699 V656A probably benign Het
Hpse2 A T 19: 43,294,253 V187D probably damaging Het
Itsn2 T A 12: 4,629,557 M122K possibly damaging Het
Kcnj11 A G 7: 46,099,789 S37P probably benign Het
Kif13b T C 14: 64,800,358 I1491T probably damaging Het
Krt36 T A 11: 100,105,164 K145* probably null Het
Loxhd1 A G 18: 77,369,137 I499V probably benign Het
Map3k4 G T 17: 12,271,610 N311K probably damaging Het
Mical2 C A 7: 112,335,413 H880N probably benign Het
Myo1d A T 11: 80,637,997 C666* probably null Het
Nlrx1 C T 9: 44,264,005 R158H probably benign Het
Olfr1115 T A 2: 87,251,951 Y5N probably benign Het
Olfr1251 T C 2: 89,666,972 S305G probably benign Het
Olfr1494 C A 19: 13,749,630 H175N possibly damaging Het
Olfr380 A T 11: 73,453,280 L311I probably benign Het
Olfr45 A G 7: 140,691,111 T69A probably benign Het
Pdgfrl A G 8: 40,977,057 R154G probably benign Het
Pitpnb T C 5: 111,330,833 F7S possibly damaging Het
Ppm1n G A 7: 19,279,172 R285C probably damaging Het
Prdm11 A T 2: 92,975,612 I331N possibly damaging Het
Ptprb C T 10: 116,367,521 P2066L probably damaging Het
Ric8b T C 10: 84,992,271 probably benign Het
Setx A G 2: 29,173,653 I2320M probably damaging Het
Skil C A 3: 31,111,638 S368* probably null Het
Slc1a5 G T 7: 16,785,719 probably null Het
Trpm7 A C 2: 126,819,891 V1079G possibly damaging Het
Tulp1 A G 17: 28,358,659 F2L probably damaging Het
Zbtb17 A G 4: 141,461,913 Y48C probably damaging Het
Zfp605 T A 5: 110,127,640 I208N possibly damaging Het
Other mutations in Clec4b2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00956:Clec4b2 APN 6 123202151 nonsense probably null
IGL01753:Clec4b2 APN 6 123202210 missense possibly damaging 0.90
IGL02168:Clec4b2 APN 6 123204197 missense probably damaging 0.98
IGL03194:Clec4b2 APN 6 123200987 missense probably benign 0.07
P0041:Clec4b2 UTSW 6 123181294 missense possibly damaging 0.72
R0013:Clec4b2 UTSW 6 123202149 missense probably damaging 1.00
R0121:Clec4b2 UTSW 6 123204172 missense probably benign 0.02
R0401:Clec4b2 UTSW 6 123181300 nonsense probably null
R1072:Clec4b2 UTSW 6 123204274 missense probably damaging 0.99
R2520:Clec4b2 UTSW 6 123200983 missense probably damaging 1.00
R4575:Clec4b2 UTSW 6 123173680 missense probably damaging 0.99
R4897:Clec4b2 UTSW 6 123201040 nonsense probably null
R4898:Clec4b2 UTSW 6 123204204 missense probably benign 0.36
R5022:Clec4b2 UTSW 6 123200956 missense probably null 1.00
R5023:Clec4b2 UTSW 6 123200956 missense probably null 1.00
R5057:Clec4b2 UTSW 6 123200956 missense probably null 1.00
R5404:Clec4b2 UTSW 6 123181349 missense probably benign 0.06
R5508:Clec4b2 UTSW 6 123173042 start gained probably benign
R6082:Clec4b2 UTSW 6 123204141 critical splice acceptor site probably null
R6333:Clec4b2 UTSW 6 123200678 unclassified probably null
R6902:Clec4b2 UTSW 6 123201028 nonsense probably null
R6946:Clec4b2 UTSW 6 123201028 nonsense probably null
R7144:Clec4b2 UTSW 6 123181384 missense probably benign 0.02
Posted On2015-04-16