Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02431:Gm10134'

293131

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm10134

Ensembl Gene

ENSMUSG00000063611

Gene Name

predicted gene 10134

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.056) question?

Stock #

IGL02431

Quality Score

Status

Chromosome

Chromosomal Location

28396107-28397785 bp(+) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 28396429 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000127071 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000028172] [ENSMUST00000074761] [ENSMUST00000163121]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000028172

SMART Domains

Protein: ENSMUSP00000028172
Gene: ENSMUSG00000026829

Domain	Start	End	E-Value	Type
transmembrane domain	7	24	N/A	INTRINSIC
Pfam:Glyco_transf_6	33	347	1.6e-154	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000074761
AA Change: V108A

SMART Domains

Protein: ENSMUSP00000082978
Gene: ENSMUSG00000063611
AA Change: V108A

Domain	Start	End	E-Value	Type
transmembrane domain	5	27	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000127958

Predicted Effect

probably benign
Transcript: ENSMUST00000163121

SMART Domains

Protein: ENSMUSP00000127071
Gene: ENSMUSG00000026829

Domain	Start	End	E-Value	Type
Pfam:Glyco_transf_6	11	347	1.9e-152	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca17	T	A	17: 24,517,958 (GRCm39)	I784L	probably benign	Het
Abcc1	T	A	16: 14,237,598 (GRCm39)	V473E	probably damaging	Het
Agap3	A	G	5: 24,706,010 (GRCm39)	E758G	probably damaging	Het
C6	A	T	15: 4,789,343 (GRCm39)	K263*	probably null	Het
Cep78	T	C	19: 15,936,943 (GRCm39)	T588A	probably benign	Het
Cfap20dc	T	C	14: 8,659,424 (GRCm38)	N57S	probably damaging	Het
Col4a3	C	T	1: 82,657,344 (GRCm39)	Q815*	probably null	Het
Dcaf10	A	G	4: 45,342,630 (GRCm39)	M155V	probably benign	Het
Fam228b	T	C	12: 4,812,370 (GRCm39)	Y136C	probably damaging	Het
Fryl	A	T	5: 73,255,651 (GRCm39)	H793Q	probably benign	Het
Gm6505	T	C	3: 28,819,169 (GRCm39)		noncoding transcript	Het
Il31ra	A	G	13: 112,666,830 (GRCm39)	F416S	probably damaging	Het
Lipc	A	G	9: 70,841,750 (GRCm39)		probably benign	Het
Lrp4	A	G	2: 91,306,982 (GRCm39)	K368E	possibly damaging	Het
Lrriq1	A	T	10: 103,036,500 (GRCm39)	N884K	probably damaging	Het
Mrgprx1	T	C	7: 47,670,875 (GRCm39)	R291G	probably benign	Het
Myo15a	T	A	11: 60,401,465 (GRCm39)	V3057E	possibly damaging	Het
Or11g1	T	A	14: 50,651,226 (GRCm39)	I75N	probably damaging	Het
Or14j8	T	A	17: 38,263,413 (GRCm39)	R167S	probably benign	Het
Postn	A	T	3: 54,282,517 (GRCm39)	I493F	probably damaging	Het
Ptpn22	C	A	3: 103,810,713 (GRCm39)	F713L	probably benign	Het
Pygm	T	C	19: 6,438,148 (GRCm39)	V239A	probably damaging	Het
Rangrf	C	A	11: 68,863,565 (GRCm39)	C147F	probably benign	Het
Rnf112	C	T	11: 61,341,205 (GRCm39)	R460H	probably benign	Het
Sh3d19	A	G	3: 86,014,305 (GRCm39)	E423G	probably damaging	Het
Tasor2	A	G	13: 3,624,736 (GRCm39)	V1738A	possibly damaging	Het
Tipin	A	G	9: 64,208,467 (GRCm39)	K204E	probably benign	Het
Traf3ip1	A	T	1: 91,427,357 (GRCm39)	Q109L	unknown	Het
Ttc21b	A	T	2: 66,082,229 (GRCm39)		probably benign	Het
Ttn	C	A	2: 76,804,460 (GRCm39)	A271S	probably benign	Het
Vegfb	C	A	19: 6,963,386 (GRCm39)		probably null	Het
Vmn1r15	T	A	6: 57,235,888 (GRCm39)	L252H	possibly damaging	Het
Wipi1	A	T	11: 109,494,617 (GRCm39)	V72D	probably damaging	Het
Zmym1	G	A	4: 126,941,557 (GRCm39)	Q944*	probably null	Het

Other mutations in Gm10134

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R2339:Gm10134	UTSW	2	28,396,141 (GRCm39)	missense	probably benign	0.34
R5288:Gm10134	UTSW	2	28,396,372 (GRCm39)	unclassified	probably benign
R5385:Gm10134	UTSW	2	28,396,372 (GRCm39)	unclassified	probably benign
R5994:Gm10134	UTSW	2	28,396,258 (GRCm39)	missense	probably damaging	0.98
R6668:Gm10134	UTSW	2	28,396,263 (GRCm39)	nonsense	probably null
R7594:Gm10134	UTSW	2	28,396,372 (GRCm39)	missense	unknown

Posted On

2015-04-16