Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02442:Mycbp2'

293469

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Mycbp2

Ensembl Gene

ENSMUSG00000033004

Gene Name

MYC binding protein 2, E3 ubiquitin protein ligase

Synonyms

Phr1, Pam, C130061D10Rik

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL02442

Quality Score

Status

Chromosome

Chromosomal Location

103350847-103584250 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 103551811 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Arginine at position 140 (K140R)

Ref Sequence

ENSEMBL: ENSMUSP00000124601 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000159855] [ENSMUST00000160758]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000159855
AA Change: K173R

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000124710
Gene: ENSMUSG00000033004
AA Change: K173R

Domain	Start	End	E-Value	Type
low complexity region	5	27	N/A	INTRINSIC
low complexity region	47	55	N/A	INTRINSIC
low complexity region	100	127	N/A	INTRINSIC
low complexity region	178	191	N/A	INTRINSIC
Pfam:RCC1_2	683	712	1.4e-10	PFAM
low complexity region	737	750	N/A	INTRINSIC
low complexity region	793	815	N/A	INTRINSIC
Pfam:RCC1_2	942	971	5.5e-10	PFAM
Pfam:RCC1	958	1006	4.8e-15	PFAM
Pfam:PHR	1235	1385	8.2e-44	PFAM
Pfam:PHR	1723	1880	1.4e-43	PFAM
low complexity region	1935	1948	N/A	INTRINSIC
low complexity region	2182	2195	N/A	INTRINSIC
Pfam:Filamin	2261	2431	7.5e-9	PFAM
Pfam:SH3_3	2472	2539	4.1e-9	PFAM
internal_repeat_3	2612	2679	1.69e-7	PROSPERO
low complexity region	2701	2710	N/A	INTRINSIC
low complexity region	2884	2917	N/A	INTRINSIC
low complexity region	2970	2984	N/A	INTRINSIC
coiled coil region	3263	3290	N/A	INTRINSIC
low complexity region	3352	3365	N/A	INTRINSIC
low complexity region	3418	3433	N/A	INTRINSIC
low complexity region	3678	3695	N/A	INTRINSIC
APC10	3810	3968	1.11e-18	SMART
low complexity region	4103	4115	N/A	INTRINSIC
low complexity region	4190	4212	N/A	INTRINSIC
Blast:BBOX	4327	4370	7e-7	BLAST
RING	4496	4546	5.35e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000160758
AA Change: K140R

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000124601
Gene: ENSMUSG00000033004
AA Change: K140R

Domain	Start	End	E-Value	Type
low complexity region	14	22	N/A	INTRINSIC
low complexity region	67	94	N/A	INTRINSIC
low complexity region	145	158	N/A	INTRINSIC
Pfam:RCC1_2	650	679	1e-10	PFAM
low complexity region	704	717	N/A	INTRINSIC
low complexity region	760	782	N/A	INTRINSIC
Pfam:RCC1_2	909	938	1.5e-9	PFAM
Pfam:RCC1	925	973	1.3e-15	PFAM
Pfam:PHR	1202	1353	1.6e-50	PFAM
Pfam:PHR	1690	1848	3.1e-58	PFAM
low complexity region	1902	1915	N/A	INTRINSIC
low complexity region	2149	2162	N/A	INTRINSIC
Pfam:Filamin	2228	2398	7.6e-9	PFAM
Pfam:SH3_3	2439	2507	2.3e-10	PFAM
internal_repeat_3	2554	2621	2e-7	PROSPERO
low complexity region	2643	2652	N/A	INTRINSIC
low complexity region	2774	2807	N/A	INTRINSIC
low complexity region	2860	2874	N/A	INTRINSIC
coiled coil region	3153	3180	N/A	INTRINSIC
low complexity region	3242	3255	N/A	INTRINSIC
low complexity region	3308	3323	N/A	INTRINSIC
low complexity region	3568	3585	N/A	INTRINSIC
APC10	3700	3858	1.11e-18	SMART
low complexity region	3993	4005	N/A	INTRINSIC
low complexity region	4080	4102	N/A	INTRINSIC
Blast:BBOX	4217	4260	7e-7	BLAST
RING	4386	4436	5.35e-5	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000162537

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a targeted allele exhibit neonatal lethality, defective diaphragm innervation, abnormal brain morphology and defective axonal guidance. [provided by MGI curators]

Allele List at MGI

All alleles(10) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(5) Chemically induced(3)

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adap2	A	G	11: 80,068,032 (GRCm39)	E348G	probably damaging	Het
Ahnak	G	A	19: 8,981,380 (GRCm39)	G888D	probably damaging	Het
Cdc45	C	T	16: 18,617,479 (GRCm39)	M200I	probably benign	Het
Cfap97d1	T	C	11: 101,881,652 (GRCm39)	V116A	probably benign	Het
Csde1	T	C	3: 102,962,135 (GRCm39)	C649R	probably benign	Het
Cym	A	C	3: 107,121,601 (GRCm39)	D230E	probably damaging	Het
Dnah1	A	T	14: 31,009,835 (GRCm39)	I1911N	probably damaging	Het
Fat1	A	G	8: 45,403,360 (GRCm39)	H37R	probably benign	Het
Ggt6	T	C	11: 72,327,632 (GRCm39)	V146A	possibly damaging	Het
Glud1	T	A	14: 34,057,395 (GRCm39)	L54*	probably null	Het
Grk6	A	G	13: 55,606,750 (GRCm39)		probably benign	Het
Gsta4	G	A	9: 78,116,447 (GRCm39)	V219I	probably benign	Het
Gucy1a2	G	A	9: 3,865,385 (GRCm39)	V620M	probably damaging	Het
Hspe1	T	C	1: 55,128,201 (GRCm39)		probably benign	Het
Icmt	T	C	4: 152,383,173 (GRCm39)	V76A	possibly damaging	Het
Ifrd1	A	G	12: 40,266,316 (GRCm39)		probably benign	Het
Lgals12	T	C	19: 7,584,019 (GRCm39)		probably benign	Het
Lypla1	T	C	1: 4,902,610 (GRCm39)		probably benign	Het
Map1b	A	T	13: 99,644,706 (GRCm39)	W66R	probably damaging	Het
Matn3	T	A	12: 9,017,678 (GRCm39)	C443*	probably null	Het
Mup8	T	A	4: 60,219,695 (GRCm39)	R191W	probably damaging	Het
Ndfip1	C	T	18: 38,580,789 (GRCm39)	S66L	probably damaging	Het
Neu1	A	G	17: 35,153,445 (GRCm39)	I323V	probably benign	Het
Nup205	A	T	6: 35,167,003 (GRCm39)	T341S	probably benign	Het
Or4f7	G	A	2: 111,644,336 (GRCm39)	T245I	probably benign	Het
Or5b112	T	A	19: 13,319,484 (GRCm39)	C121S	probably benign	Het
Or5b3	T	A	19: 13,388,351 (GRCm39)	N139K	probably benign	Het
Ovch2	T	A	7: 107,395,755 (GRCm39)	I88F	possibly damaging	Het
Pkd1	T	A	17: 24,784,200 (GRCm39)	S249T	probably benign	Het
Plekhg3	A	T	12: 76,625,127 (GRCm39)	Q1324L	probably benign	Het
Ppara	T	A	15: 85,685,344 (GRCm39)	V431E	probably benign	Het
Prkaa1	T	G	15: 5,206,369 (GRCm39)	H408Q	probably damaging	Het
Sap25	T	A	5: 137,640,257 (GRCm39)	N108K	probably benign	Het
Setd5	A	C	6: 113,087,341 (GRCm39)	I81L	possibly damaging	Het
Sinhcaf	A	T	6: 148,830,005 (GRCm39)		probably null	Het
Sri	T	A	5: 8,112,411 (GRCm39)	M78K	probably damaging	Het
Tyro3	A	G	2: 119,639,349 (GRCm39)	N352S	probably benign	Het
Ubr5	T	A	15: 38,038,145 (GRCm39)	E332V	possibly damaging	Het
Vmn2r19	G	T	6: 123,286,621 (GRCm39)	V85F	possibly damaging	Het
Vmn2r53	A	T	7: 12,315,656 (GRCm39)	V721D	probably damaging	Het
Vwa5a	A	G	9: 38,646,080 (GRCm39)	M483V	probably benign	Het
Zfp786	T	A	6: 47,798,301 (GRCm39)	Q212H	probably benign	Het

Other mutations in Mycbp2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Mycbp2	APN	14	103,460,486 (GRCm39)	missense	probably damaging	1.00
IGL00518:Mycbp2	APN	14	103,393,244 (GRCm39)	missense	probably damaging	1.00
IGL00650:Mycbp2	APN	14	103,380,664 (GRCm39)	missense	probably damaging	0.97
IGL00653:Mycbp2	APN	14	103,380,664 (GRCm39)	missense	probably damaging	0.97
IGL00742:Mycbp2	APN	14	103,438,788 (GRCm39)	missense	probably damaging	1.00
IGL00755:Mycbp2	APN	14	103,432,057 (GRCm39)	missense	possibly damaging	0.72
IGL00793:Mycbp2	APN	14	103,364,189 (GRCm39)	missense	possibly damaging	0.77
IGL00916:Mycbp2	APN	14	103,528,719 (GRCm39)	splice site	probably benign
IGL00960:Mycbp2	APN	14	103,466,820 (GRCm39)	missense	possibly damaging	0.95
IGL00977:Mycbp2	APN	14	103,410,078 (GRCm39)	missense	probably damaging	0.98
IGL01349:Mycbp2	APN	14	103,359,983 (GRCm39)	missense	probably damaging	0.98
IGL01369:Mycbp2	APN	14	103,392,946 (GRCm39)	missense	possibly damaging	0.61
IGL01410:Mycbp2	APN	14	103,466,928 (GRCm39)	splice site	probably null
IGL01586:Mycbp2	APN	14	103,378,305 (GRCm39)	critical splice donor site	probably null
IGL01593:Mycbp2	APN	14	103,528,723 (GRCm39)	critical splice donor site	probably null
IGL01693:Mycbp2	APN	14	103,365,415 (GRCm39)	missense	probably damaging	0.99
IGL01730:Mycbp2	APN	14	103,372,640 (GRCm39)	nonsense	probably null
IGL01820:Mycbp2	APN	14	103,425,937 (GRCm39)	missense	probably damaging	1.00
IGL01974:Mycbp2	APN	14	103,380,647 (GRCm39)	missense	possibly damaging	0.88
IGL02071:Mycbp2	APN	14	103,392,343 (GRCm39)	nonsense	probably null
IGL02178:Mycbp2	APN	14	103,461,802 (GRCm39)	missense	probably benign	0.01
IGL02324:Mycbp2	APN	14	103,479,643 (GRCm39)	missense	probably damaging	1.00
IGL02607:Mycbp2	APN	14	103,522,709 (GRCm39)	missense	probably damaging	1.00
IGL02679:Mycbp2	APN	14	103,442,621 (GRCm39)	missense	probably benign
IGL02702:Mycbp2	APN	14	103,457,560 (GRCm39)	missense	probably benign	0.01
IGL02709:Mycbp2	APN	14	103,392,697 (GRCm39)	missense	probably damaging	0.97
IGL02736:Mycbp2	APN	14	103,351,678 (GRCm39)	splice site	probably benign
IGL02866:Mycbp2	APN	14	103,367,428 (GRCm39)	missense	probably damaging	0.98
IGL02939:Mycbp2	APN	14	103,414,715 (GRCm39)	missense	probably benign
IGL03082:Mycbp2	APN	14	103,441,805 (GRCm39)	missense	probably benign	0.23
IGL03142:Mycbp2	APN	14	103,536,212 (GRCm39)	missense	probably damaging	0.99
IGL03155:Mycbp2	APN	14	103,392,889 (GRCm39)	missense	probably benign	0.06
IGL03236:Mycbp2	APN	14	103,536,134 (GRCm39)	missense	probably damaging	0.99
IGL03256:Mycbp2	APN	14	103,426,025 (GRCm39)	missense	possibly damaging	0.92
IGL03303:Mycbp2	APN	14	103,485,194 (GRCm39)	missense	probably damaging	1.00
compost	UTSW	14	103,393,889 (GRCm39)	missense	probably damaging	1.00
decompose	UTSW	14	103,457,415 (GRCm39)	missense	probably benign	0.12
moulder	UTSW	14	103,426,028 (GRCm39)	missense	probably damaging	1.00
N/A - 293:Mycbp2	UTSW	14	103,461,898 (GRCm39)	splice site	probably benign
R0040:Mycbp2	UTSW	14	103,461,708 (GRCm39)	missense	probably benign	0.11
R0040:Mycbp2	UTSW	14	103,461,708 (GRCm39)	missense	probably benign	0.11
R0057:Mycbp2	UTSW	14	103,389,578 (GRCm39)	missense	probably damaging	0.97
R0063:Mycbp2	UTSW	14	103,394,070 (GRCm39)	unclassified	probably benign
R0097:Mycbp2	UTSW	14	103,393,198 (GRCm39)	missense	probably damaging	1.00
R0097:Mycbp2	UTSW	14	103,393,198 (GRCm39)	missense	probably damaging	1.00
R0268:Mycbp2	UTSW	14	103,551,761 (GRCm39)	nonsense	probably null
R0388:Mycbp2	UTSW	14	103,394,103 (GRCm39)	missense	probably benign	0.01
R0410:Mycbp2	UTSW	14	103,372,569 (GRCm39)	missense	probably damaging	1.00
R0530:Mycbp2	UTSW	14	103,419,895 (GRCm39)	missense	probably damaging	1.00
R0591:Mycbp2	UTSW	14	103,433,827 (GRCm39)	unclassified	probably benign
R0671:Mycbp2	UTSW	14	103,432,024 (GRCm39)	missense	possibly damaging	0.95
R0755:Mycbp2	UTSW	14	103,412,230 (GRCm39)	missense	probably damaging	1.00
R0817:Mycbp2	UTSW	14	103,466,854 (GRCm39)	missense	probably damaging	0.99
R0818:Mycbp2	UTSW	14	103,466,854 (GRCm39)	missense	probably damaging	0.99
R0819:Mycbp2	UTSW	14	103,466,854 (GRCm39)	missense	probably damaging	0.99
R0881:Mycbp2	UTSW	14	103,457,449 (GRCm39)	missense	probably benign
R0903:Mycbp2	UTSW	14	103,513,293 (GRCm39)	missense	probably damaging	0.99
R0940:Mycbp2	UTSW	14	103,500,129 (GRCm39)	unclassified	probably benign
R0961:Mycbp2	UTSW	14	103,422,271 (GRCm39)	missense	probably damaging	1.00
R1004:Mycbp2	UTSW	14	103,378,353 (GRCm39)	missense	probably benign	0.00
R1138:Mycbp2	UTSW	14	103,412,262 (GRCm39)	missense	possibly damaging	0.84
R1170:Mycbp2	UTSW	14	103,437,588 (GRCm39)	nonsense	probably null
R1211:Mycbp2	UTSW	14	103,357,999 (GRCm39)	missense	probably benign	0.31
R1268:Mycbp2	UTSW	14	103,446,218 (GRCm39)	missense	probably damaging	1.00
R1298:Mycbp2	UTSW	14	103,393,334 (GRCm39)	missense	probably damaging	1.00
R1341:Mycbp2	UTSW	14	103,536,303 (GRCm39)	splice site	probably benign
R1469:Mycbp2	UTSW	14	103,425,956 (GRCm39)	missense	probably damaging	0.99
R1469:Mycbp2	UTSW	14	103,425,956 (GRCm39)	missense	probably damaging	0.99
R1513:Mycbp2	UTSW	14	103,441,825 (GRCm39)	missense	probably damaging	1.00
R1528:Mycbp2	UTSW	14	103,470,033 (GRCm39)	missense	possibly damaging	0.91
R1564:Mycbp2	UTSW	14	103,407,287 (GRCm39)	splice site	probably null
R1565:Mycbp2	UTSW	14	103,489,945 (GRCm39)	missense	possibly damaging	0.82
R1656:Mycbp2	UTSW	14	103,485,194 (GRCm39)	missense	probably damaging	1.00
R1694:Mycbp2	UTSW	14	103,464,947 (GRCm39)	missense	probably damaging	1.00
R1709:Mycbp2	UTSW	14	103,461,852 (GRCm39)	missense	probably damaging	1.00
R1728:Mycbp2	UTSW	14	103,392,614 (GRCm39)	missense	probably damaging	0.98
R1751:Mycbp2	UTSW	14	103,485,841 (GRCm39)	missense	probably damaging	0.98
R1767:Mycbp2	UTSW	14	103,485,841 (GRCm39)	missense	probably damaging	0.98
R1772:Mycbp2	UTSW	14	103,419,855 (GRCm39)	missense	probably damaging	1.00
R1784:Mycbp2	UTSW	14	103,392,614 (GRCm39)	missense	probably damaging	0.98
R1823:Mycbp2	UTSW	14	103,489,945 (GRCm39)	missense	possibly damaging	0.82
R1824:Mycbp2	UTSW	14	103,489,945 (GRCm39)	missense	possibly damaging	0.82
R1844:Mycbp2	UTSW	14	103,393,150 (GRCm39)	missense	possibly damaging	0.94
R1916:Mycbp2	UTSW	14	103,422,319 (GRCm39)	missense	probably damaging	1.00
R1944:Mycbp2	UTSW	14	103,466,840 (GRCm39)	missense	probably damaging	1.00
R1983:Mycbp2	UTSW	14	103,383,407 (GRCm39)	missense	probably damaging	0.97
R2002:Mycbp2	UTSW	14	103,485,839 (GRCm39)	missense	probably damaging	0.98
R2031:Mycbp2	UTSW	14	103,426,028 (GRCm39)	missense	probably damaging	1.00
R2035:Mycbp2	UTSW	14	103,497,675 (GRCm39)	missense	probably damaging	1.00
R2048:Mycbp2	UTSW	14	103,469,960 (GRCm39)	critical splice donor site	probably null
R2061:Mycbp2	UTSW	14	103,524,696 (GRCm39)	missense	probably damaging	0.99
R2113:Mycbp2	UTSW	14	103,457,512 (GRCm39)	missense	probably damaging	0.99
R2128:Mycbp2	UTSW	14	103,438,666 (GRCm39)	missense	probably benign	0.01
R2134:Mycbp2	UTSW	14	103,446,329 (GRCm39)	missense	probably damaging	1.00
R2135:Mycbp2	UTSW	14	103,446,329 (GRCm39)	missense	probably damaging	1.00
R2135:Mycbp2	UTSW	14	103,383,378 (GRCm39)	missense	probably benign
R2146:Mycbp2	UTSW	14	103,393,358 (GRCm39)	missense	probably damaging	0.97
R2147:Mycbp2	UTSW	14	103,393,358 (GRCm39)	missense	probably damaging	0.97
R2148:Mycbp2	UTSW	14	103,393,358 (GRCm39)	missense	probably damaging	0.97
R2150:Mycbp2	UTSW	14	103,393,358 (GRCm39)	missense	probably damaging	0.97
R2163:Mycbp2	UTSW	14	103,407,291 (GRCm39)	critical splice donor site	probably null
R2248:Mycbp2	UTSW	14	103,407,295 (GRCm39)	missense	possibly damaging	0.50
R2265:Mycbp2	UTSW	14	103,500,185 (GRCm39)	missense	probably benign	0.39
R2272:Mycbp2	UTSW	14	103,381,774 (GRCm39)	missense	probably null	0.66
R2379:Mycbp2	UTSW	14	103,412,386 (GRCm39)	missense	probably benign
R2495:Mycbp2	UTSW	14	103,437,554 (GRCm39)	missense	probably damaging	0.99
R2508:Mycbp2	UTSW	14	103,368,681 (GRCm39)	missense	probably damaging	0.99
R2510:Mycbp2	UTSW	14	103,392,691 (GRCm39)	missense	probably damaging	0.96
R2851:Mycbp2	UTSW	14	103,381,769 (GRCm39)	missense	probably damaging	0.99
R2852:Mycbp2	UTSW	14	103,381,769 (GRCm39)	missense	probably damaging	0.99
R2965:Mycbp2	UTSW	14	103,534,794 (GRCm39)	missense	probably benign	0.00
R3156:Mycbp2	UTSW	14	103,446,179 (GRCm39)	splice site	probably benign
R3404:Mycbp2	UTSW	14	103,437,550 (GRCm39)	missense	probably damaging	0.99
R3410:Mycbp2	UTSW	14	103,372,553 (GRCm39)	missense	probably damaging	1.00
R3429:Mycbp2	UTSW	14	103,466,866 (GRCm39)	missense	probably damaging	1.00
R3706:Mycbp2	UTSW	14	103,393,850 (GRCm39)	missense	probably benign	0.31
R3772:Mycbp2	UTSW	14	103,371,224 (GRCm39)	missense	possibly damaging	0.82
R3778:Mycbp2	UTSW	14	103,434,721 (GRCm39)	missense	probably damaging	0.99
R3883:Mycbp2	UTSW	14	103,532,686 (GRCm39)	missense	probably damaging	0.97
R3884:Mycbp2	UTSW	14	103,532,686 (GRCm39)	missense	probably damaging	0.97
R3887:Mycbp2	UTSW	14	103,412,233 (GRCm39)	missense	probably damaging	0.98
R3923:Mycbp2	UTSW	14	103,364,149 (GRCm39)	missense	probably damaging	1.00
R3926:Mycbp2	UTSW	14	103,441,936 (GRCm39)	missense	probably damaging	1.00
R3959:Mycbp2	UTSW	14	103,532,688 (GRCm39)	missense	probably benign	0.00
R3966:Mycbp2	UTSW	14	103,376,161 (GRCm39)	splice site	probably benign
R4021:Mycbp2	UTSW	14	103,389,593 (GRCm39)	missense	probably damaging	0.97
R4363:Mycbp2	UTSW	14	103,485,893 (GRCm39)	missense	probably damaging	1.00
R4405:Mycbp2	UTSW	14	103,360,881 (GRCm39)	missense	probably damaging	1.00
R4407:Mycbp2	UTSW	14	103,524,664 (GRCm39)	missense	probably damaging	1.00
R4410:Mycbp2	UTSW	14	103,372,702 (GRCm39)	missense	probably damaging	1.00
R4434:Mycbp2	UTSW	14	103,371,225 (GRCm39)	missense	probably damaging	0.99
R4448:Mycbp2	UTSW	14	103,425,938 (GRCm39)	missense	possibly damaging	0.89
R4452:Mycbp2	UTSW	14	103,393,094 (GRCm39)	missense	probably damaging	0.99
R4573:Mycbp2	UTSW	14	103,583,733 (GRCm39)	missense	probably benign	0.05
R4589:Mycbp2	UTSW	14	103,414,749 (GRCm39)	missense	probably benign	0.04
R4621:Mycbp2	UTSW	14	103,457,415 (GRCm39)	missense	probably benign	0.12
R4622:Mycbp2	UTSW	14	103,457,415 (GRCm39)	missense	probably benign	0.12
R4729:Mycbp2	UTSW	14	103,426,027 (GRCm39)	missense	probably damaging	1.00
R4770:Mycbp2	UTSW	14	103,457,380 (GRCm39)	missense	probably benign	0.41
R4790:Mycbp2	UTSW	14	103,466,873 (GRCm39)	missense	probably damaging	1.00
R4884:Mycbp2	UTSW	14	103,448,731 (GRCm39)	missense	probably damaging	1.00
R4885:Mycbp2	UTSW	14	103,383,382 (GRCm39)	missense	possibly damaging	0.86
R4956:Mycbp2	UTSW	14	103,524,675 (GRCm39)	missense	probably damaging	0.99
R4980:Mycbp2	UTSW	14	103,497,821 (GRCm39)	splice site	probably null
R4994:Mycbp2	UTSW	14	103,407,430 (GRCm39)	missense	probably benign
R5029:Mycbp2	UTSW	14	103,393,946 (GRCm39)	missense	probably benign	0.21
R5038:Mycbp2	UTSW	14	103,534,375 (GRCm39)	missense	probably damaging	1.00
R5044:Mycbp2	UTSW	14	103,376,671 (GRCm39)	critical splice donor site	probably null
R5231:Mycbp2	UTSW	14	103,583,650 (GRCm39)	critical splice donor site	probably null
R5305:Mycbp2	UTSW	14	103,583,757 (GRCm39)	missense	probably benign	0.00
R5322:Mycbp2	UTSW	14	103,423,119 (GRCm39)	critical splice acceptor site	probably null
R5376:Mycbp2	UTSW	14	103,479,868 (GRCm39)	nonsense	probably null
R5414:Mycbp2	UTSW	14	103,543,697 (GRCm39)	missense	probably damaging	1.00
R5453:Mycbp2	UTSW	14	103,438,837 (GRCm39)	missense	probably damaging	0.99
R5462:Mycbp2	UTSW	14	103,437,562 (GRCm39)	missense	probably damaging	1.00
R5499:Mycbp2	UTSW	14	103,479,615 (GRCm39)	missense	probably damaging	1.00
R5502:Mycbp2	UTSW	14	103,411,250 (GRCm39)	missense	probably damaging	1.00
R5524:Mycbp2	UTSW	14	103,532,673 (GRCm39)	missense	probably damaging	1.00
R5533:Mycbp2	UTSW	14	103,520,081 (GRCm39)	nonsense	probably null
R5569:Mycbp2	UTSW	14	103,372,679 (GRCm39)	missense	probably damaging	1.00
R5574:Mycbp2	UTSW	14	103,380,203 (GRCm39)	missense	possibly damaging	0.94
R5579:Mycbp2	UTSW	14	103,528,769 (GRCm39)	missense	probably damaging	0.98
R5590:Mycbp2	UTSW	14	103,360,791 (GRCm39)	missense	probably damaging	1.00
R5592:Mycbp2	UTSW	14	103,432,113 (GRCm39)	missense	probably benign	0.02
R5643:Mycbp2	UTSW	14	103,524,770 (GRCm39)	missense	probably damaging	1.00
R5644:Mycbp2	UTSW	14	103,524,770 (GRCm39)	missense	probably damaging	1.00
R5645:Mycbp2	UTSW	14	103,426,051 (GRCm39)	critical splice acceptor site	probably null
R5645:Mycbp2	UTSW	14	103,426,044 (GRCm39)	missense	probably damaging	1.00
R5646:Mycbp2	UTSW	14	103,407,346 (GRCm39)	missense	probably benign	0.09
R5648:Mycbp2	UTSW	14	103,528,778 (GRCm39)	missense	probably damaging	1.00
R5651:Mycbp2	UTSW	14	103,520,101 (GRCm39)	missense	probably null	0.99
R5668:Mycbp2	UTSW	14	103,357,955 (GRCm39)	missense	possibly damaging	0.62
R5745:Mycbp2	UTSW	14	103,393,889 (GRCm39)	missense	possibly damaging	0.94
R5751:Mycbp2	UTSW	14	103,385,986 (GRCm39)	missense	probably damaging	0.99
R5756:Mycbp2	UTSW	14	103,371,410 (GRCm39)	missense	probably damaging	0.99
R5837:Mycbp2	UTSW	14	103,361,839 (GRCm39)	missense	probably damaging	1.00
R5984:Mycbp2	UTSW	14	103,364,120 (GRCm39)	missense	probably damaging	0.98
R6005:Mycbp2	UTSW	14	103,394,159 (GRCm39)	missense	probably benign
R6063:Mycbp2	UTSW	14	103,372,582 (GRCm39)	missense	probably damaging	1.00
R6091:Mycbp2	UTSW	14	103,460,482 (GRCm39)	missense	probably damaging	1.00
R6120:Mycbp2	UTSW	14	103,513,323 (GRCm39)	missense	probably benign	0.01
R6129:Mycbp2	UTSW	14	103,522,836 (GRCm39)	missense	probably benign	0.21
R6147:Mycbp2	UTSW	14	103,392,945 (GRCm39)	nonsense	probably null
R6161:Mycbp2	UTSW	14	103,536,183 (GRCm39)	missense	probably damaging	1.00
R6187:Mycbp2	UTSW	14	103,384,453 (GRCm39)	missense	probably damaging	1.00
R6208:Mycbp2	UTSW	14	103,532,664 (GRCm39)	missense	probably benign	0.11
R6228:Mycbp2	UTSW	14	103,497,665 (GRCm39)	missense	probably benign	0.24
R6301:Mycbp2	UTSW	14	103,392,862 (GRCm39)	missense	probably damaging	1.00
R6311:Mycbp2	UTSW	14	103,500,176 (GRCm39)	missense	possibly damaging	0.93
R6329:Mycbp2	UTSW	14	103,393,288 (GRCm39)	missense	probably benign	0.00
R6439:Mycbp2	UTSW	14	103,392,911 (GRCm39)	missense	probably benign	0.00
R6462:Mycbp2	UTSW	14	103,373,993 (GRCm39)	critical splice donor site	probably null
R6528:Mycbp2	UTSW	14	103,380,317 (GRCm39)	missense	probably damaging	0.99
R6736:Mycbp2	UTSW	14	103,429,003 (GRCm39)	missense	probably null	1.00
R6821:Mycbp2	UTSW	14	103,376,845 (GRCm39)	missense	probably damaging	1.00
R6851:Mycbp2	UTSW	14	103,497,630 (GRCm39)	critical splice donor site	probably null
R6948:Mycbp2	UTSW	14	103,522,703 (GRCm39)	missense	possibly damaging	0.94
R6977:Mycbp2	UTSW	14	103,392,342 (GRCm39)	missense	probably damaging	0.99
R6985:Mycbp2	UTSW	14	103,444,117 (GRCm39)	missense	possibly damaging	0.79
R7035:Mycbp2	UTSW	14	103,412,417 (GRCm39)	missense	probably benign
R7054:Mycbp2	UTSW	14	103,393,534 (GRCm39)	missense	possibly damaging	0.90
R7108:Mycbp2	UTSW	14	103,360,039 (GRCm39)	missense	probably damaging	1.00
R7117:Mycbp2	UTSW	14	103,391,513 (GRCm39)	missense	probably benign	0.21
R7137:Mycbp2	UTSW	14	103,520,115 (GRCm39)	missense	possibly damaging	0.94
R7169:Mycbp2	UTSW	14	103,497,636 (GRCm39)	missense	possibly damaging	0.78
R7218:Mycbp2	UTSW	14	103,371,282 (GRCm39)	missense	probably benign
R7234:Mycbp2	UTSW	14	103,452,773 (GRCm39)	missense	probably damaging	0.98
R7238:Mycbp2	UTSW	14	103,393,733 (GRCm39)	missense	probably damaging	1.00
R7244:Mycbp2	UTSW	14	103,446,345 (GRCm39)	missense	probably damaging	0.98
R7265:Mycbp2	UTSW	14	103,434,679 (GRCm39)	critical splice donor site	probably null
R7286:Mycbp2	UTSW	14	103,358,027 (GRCm39)	missense	probably damaging	1.00
R7332:Mycbp2	UTSW	14	103,434,793 (GRCm39)	missense	probably damaging	0.97
R7332:Mycbp2	UTSW	14	103,393,889 (GRCm39)	missense	probably damaging	1.00
R7384:Mycbp2	UTSW	14	103,513,829 (GRCm39)	missense	probably damaging	0.99
R7392:Mycbp2	UTSW	14	103,480,564 (GRCm39)	missense	probably damaging	0.99
R7392:Mycbp2	UTSW	14	103,389,627 (GRCm39)	missense	probably damaging	1.00
R7409:Mycbp2	UTSW	14	103,526,180 (GRCm39)	missense	probably damaging	1.00
R7486:Mycbp2	UTSW	14	103,434,690 (GRCm39)	missense	probably damaging	0.97
R7643:Mycbp2	UTSW	14	103,583,701 (GRCm39)	missense	probably benign
R7661:Mycbp2	UTSW	14	103,450,059 (GRCm39)	missense	probably damaging	1.00
R7663:Mycbp2	UTSW	14	103,429,045 (GRCm39)	missense	probably damaging	0.99
R7730:Mycbp2	UTSW	14	103,360,791 (GRCm39)	missense	probably damaging	0.99
R7757:Mycbp2	UTSW	14	103,429,055 (GRCm39)	missense	probably damaging	1.00
R7773:Mycbp2	UTSW	14	103,485,840 (GRCm39)	missense	probably damaging	0.97
R7787:Mycbp2	UTSW	14	103,364,533 (GRCm39)	missense	probably damaging	1.00
R7822:Mycbp2	UTSW	14	103,376,851 (GRCm39)	missense	probably benign	0.00
R7838:Mycbp2	UTSW	14	103,414,729 (GRCm39)	missense	probably benign	0.10
R7841:Mycbp2	UTSW	14	103,384,267 (GRCm39)	critical splice donor site	probably null
R7858:Mycbp2	UTSW	14	103,393,741 (GRCm39)	missense	probably damaging	1.00
R7873:Mycbp2	UTSW	14	103,393,582 (GRCm39)	missense	probably damaging	1.00
R7911:Mycbp2	UTSW	14	103,437,621 (GRCm39)	missense	probably damaging	0.99
R7942:Mycbp2	UTSW	14	103,392,674 (GRCm39)	missense	probably damaging	0.99
R7951:Mycbp2	UTSW	14	103,452,898 (GRCm39)	missense	probably damaging	0.99
R7958:Mycbp2	UTSW	14	103,367,400 (GRCm39)	missense	probably benign	0.00
R8235:Mycbp2	UTSW	14	103,436,110 (GRCm39)	missense	probably damaging	0.99
R8246:Mycbp2	UTSW	14	103,392,640 (GRCm39)	missense	probably damaging	0.99
R8338:Mycbp2	UTSW	14	103,372,701 (GRCm39)	missense	probably damaging	1.00
R8343:Mycbp2	UTSW	14	103,398,111 (GRCm39)	splice site	probably null
R8361:Mycbp2	UTSW	14	103,376,250 (GRCm39)	missense	probably damaging	1.00
R8490:Mycbp2	UTSW	14	103,446,267 (GRCm39)	missense	probably benign	0.00
R8524:Mycbp2	UTSW	14	103,392,895 (GRCm39)	missense	probably benign	0.23
R8525:Mycbp2	UTSW	14	103,450,155 (GRCm39)	missense	probably damaging	1.00
R8711:Mycbp2	UTSW	14	103,407,430 (GRCm39)	missense	probably benign	0.08
R8735:Mycbp2	UTSW	14	103,460,586 (GRCm39)	missense	probably damaging	0.99
R8825:Mycbp2	UTSW	14	103,466,871 (GRCm39)	missense	probably damaging	1.00
R8928:Mycbp2	UTSW	14	103,393,781 (GRCm39)	missense	probably benign
R8974:Mycbp2	UTSW	14	103,361,857 (GRCm39)	missense	probably damaging	1.00
R8987:Mycbp2	UTSW	14	103,446,232 (GRCm39)	missense	probably damaging	1.00
R9021:Mycbp2	UTSW	14	103,551,752 (GRCm39)	missense	probably benign	0.08
R9062:Mycbp2	UTSW	14	103,479,796 (GRCm39)	missense	probably benign	0.00
R9077:Mycbp2	UTSW	14	103,469,974 (GRCm39)	missense	probably damaging	1.00
R9208:Mycbp2	UTSW	14	103,532,664 (GRCm39)	missense	probably benign	0.01
R9285:Mycbp2	UTSW	14	103,434,753 (GRCm39)	missense	probably damaging	0.97
R9290:Mycbp2	UTSW	14	103,425,960 (GRCm39)	missense	probably damaging	0.99
R9362:Mycbp2	UTSW	14	103,497,642 (GRCm39)	missense	probably damaging	0.97
R9520:Mycbp2	UTSW	14	103,497,705 (GRCm39)	missense	probably benign	0.02
R9557:Mycbp2	UTSW	14	103,372,697 (GRCm39)	missense	probably benign	0.03
R9639:Mycbp2	UTSW	14	103,433,817 (GRCm39)	missense	probably damaging	1.00
R9666:Mycbp2	UTSW	14	103,371,474 (GRCm39)	missense	probably damaging	0.98
R9732:Mycbp2	UTSW	14	103,448,749 (GRCm39)	missense	probably damaging	1.00
R9736:Mycbp2	UTSW	14	103,434,852 (GRCm39)	missense	probably damaging	0.96
R9739:Mycbp2	UTSW	14	103,520,229 (GRCm39)	missense	probably benign	0.11
R9755:Mycbp2	UTSW	14	103,551,806 (GRCm39)	missense	probably benign
X0024:Mycbp2	UTSW	14	103,384,378 (GRCm39)	missense	probably damaging	1.00
Z1176:Mycbp2	UTSW	14	103,583,685 (GRCm39)	missense	probably benign
Z1176:Mycbp2	UTSW	14	103,394,073 (GRCm39)	missense	probably benign	0.06
Z1177:Mycbp2	UTSW	14	103,407,309 (GRCm39)	missense	possibly damaging	0.83
Z1177:Mycbp2	UTSW	14	103,372,559 (GRCm39)	missense	probably damaging	1.00
Z1177:Mycbp2	UTSW	14	103,364,499 (GRCm39)	critical splice donor site	probably null

Posted On

2015-04-16