Incidental Mutation 'IGL00226:Eif1ad'
ID29476
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Eif1ad
Ensembl Gene ENSMUSG00000024841
Gene Nameeukaryotic translation initiation factor 1A domain containing
Synonyms
Accession Numbers
Is this an essential gene? Essential (E-score: 1.000) question?
Stock #IGL00226
Quality Score
Status
Chromosome19
Chromosomal Location5366813-5371511 bp(+) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) A to G at 5368184 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000126202 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000025759] [ENSMUST00000025762] [ENSMUST00000170010]
Predicted Effect probably benign
Transcript: ENSMUST00000025759
SMART Domains Protein: ENSMUSP00000025759
Gene: ENSMUSG00000024841

DomainStartEndE-ValueType
eIF1a 20 103 1.03e-40 SMART
low complexity region 131 142 N/A INTRINSIC
low complexity region 154 168 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000025762
SMART Domains Protein: ENSMUSP00000025762
Gene: ENSMUSG00000024844

DomainStartEndE-ValueType
BAF 1 88 3.68e-59 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000170010
SMART Domains Protein: ENSMUSP00000126202
Gene: ENSMUSG00000024844

DomainStartEndE-ValueType
BAF 1 88 3.68e-59 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1810062G17Rik C A 3: 36,479,541 probably benign Het
5430419D17Rik T A 7: 131,238,094 probably null Het
Ankib1 G A 5: 3,727,573 S439L probably benign Het
Cpd G T 11: 76,797,789 H886N probably benign Het
Dhrs7 A G 12: 72,659,350 C94R probably damaging Het
Dmxl2 T A 9: 54,415,993 H1369L probably damaging Het
Dnah5 A G 15: 28,272,342 N1068S probably benign Het
Dopey1 T A 9: 86,551,679 D2329E possibly damaging Het
Fam149a T C 8: 45,339,343 R693G probably damaging Het
Fbxw18 T A 9: 109,693,343 T153S probably benign Het
Glg1 A T 8: 111,159,849 C1104S probably damaging Het
Jak3 T C 8: 71,681,697 probably benign Het
Kctd6 C T 14: 8,222,856 R233C possibly damaging Het
Kpna3 A G 14: 61,374,288 V300A possibly damaging Het
Msh5 A T 17: 35,029,881 Y725* probably null Het
Myh2 T C 11: 67,185,233 S749P possibly damaging Het
Olfr1215 A G 2: 89,001,339 probably benign Het
Olfr199 A T 16: 59,216,496 M39K probably damaging Het
Olfr27 T A 9: 39,144,757 I219N possibly damaging Het
Olfr697 T A 7: 106,741,701 T78S probably benign Het
Pdcd1 A G 1: 94,040,135 probably benign Het
Pde5a T A 3: 122,794,357 F391I probably damaging Het
Ptpn12 A C 5: 20,998,668 S371A probably damaging Het
Sec16b A G 1: 157,538,330 Y254C probably damaging Het
Slc2a10 G A 2: 165,514,780 C120Y probably damaging Het
Spink5 G A 18: 43,987,871 probably benign Het
Svil A G 18: 5,099,045 Q1250R probably benign Het
Tph1 G T 7: 46,656,870 N222K probably benign Het
Vmn2r83 A T 10: 79,478,971 D351V probably damaging Het
Zfp54 A G 17: 21,433,559 D105G possibly damaging Het
Zfp623 T C 15: 75,948,203 I336T probably damaging Het
Other mutations in Eif1ad
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02012:Eif1ad APN 19 5368659 missense probably damaging 1.00
IGL02541:Eif1ad APN 19 5368417 unclassified probably benign
R0699:Eif1ad UTSW 19 5368698 missense possibly damaging 0.92
R1238:Eif1ad UTSW 19 5370083 makesense probably null
R1921:Eif1ad UTSW 19 5370058 unclassified probably benign
R2242:Eif1ad UTSW 19 5370058 unclassified probably benign
R3401:Eif1ad UTSW 19 5368248 missense probably benign 0.02
R4671:Eif1ad UTSW 19 5368191 start codon destroyed probably null 1.00
Posted On2013-04-17