Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02487:Tsga13'

295484

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tsga13

Ensembl Gene

ENSMUSG00000039032

Gene Name

testis specific gene A13

Synonyms

1700023D02Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.147) question?

Stock #

IGL02487

Quality Score

Status

Chromosome

Chromosomal Location

30873916-30892508 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 30884362 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Asparagine at position 119 (Y119N)

Ref Sequence

ENSEMBL: ENSMUSP00000040894 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048580]

AlphaFold

Q9DA17

Predicted Effect

probably damaging
Transcript: ENSMUST00000048580
AA Change: Y119N

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000040894
Gene: ENSMUSG00000039032
AA Change: Y119N

Domain	Start	End	E-Value	Type
Pfam:TSGA13	3	271	9.5e-125	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000139006

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000202703

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acsl6	T	A	11: 54,227,769 (GRCm39)	I308N	possibly damaging	Het
Adal	C	T	2: 120,985,877 (GRCm39)	T204I	probably benign	Het
Akirin1	A	G	4: 123,637,357 (GRCm39)	F76S	probably benign	Het
Arhgef5	A	T	6: 43,260,916 (GRCm39)	N1447I	probably damaging	Het
Atp2a3	C	A	11: 72,866,165 (GRCm39)	H262N	probably benign	Het
B230217C12Rik	A	G	11: 97,733,054 (GRCm39)	N125S	probably benign	Het
Dcaf11	G	T	14: 55,806,571 (GRCm39)	K457N	probably benign	Het
Dnah10	G	A	5: 124,870,916 (GRCm39)	V2348M	possibly damaging	Het
Eif4g3	T	C	4: 137,930,689 (GRCm39)	V1665A	possibly damaging	Het
Fat4	A	T	3: 38,941,394 (GRCm39)	I96F	probably damaging	Het
Gm29253	T	C	1: 75,149,321 (GRCm39)		probably null	Het
Gvin-ps6	A	G	7: 106,022,471 (GRCm39)		noncoding transcript	Het
Hnrnpm	C	A	17: 33,867,787 (GRCm39)	G676C	probably damaging	Het
Iah1	T	C	12: 21,371,440 (GRCm39)	M185T	probably damaging	Het
Klc1	A	T	12: 111,738,886 (GRCm39)	I45F	probably damaging	Het
Lce1h	G	A	3: 92,671,048 (GRCm39)	P35S	unknown	Het
Lrrc37a	T	C	11: 103,386,863 (GRCm39)	E2419G	unknown	Het
Lrrc8c	T	A	5: 105,754,457 (GRCm39)	S77R	probably benign	Het
Mcm3ap	T	A	10: 76,343,389 (GRCm39)		probably benign	Het
Mon1b	G	T	8: 114,365,455 (GRCm39)	R261L	possibly damaging	Het
Ntng1	A	T	3: 109,842,363 (GRCm39)	S137T	probably damaging	Het
Odf2	C	A	2: 29,810,851 (GRCm39)	A578E	possibly damaging	Het
Pecam1	G	A	11: 106,562,606 (GRCm39)	T698I	probably damaging	Het
Pex10	A	T	4: 155,155,190 (GRCm39)	H288L	probably damaging	Het
Pkhd1l1	T	C	15: 44,322,822 (GRCm39)	V36A	possibly damaging	Het
Podxl	T	C	6: 31,499,957 (GRCm39)	*504W	probably null	Het
Rab42	A	G	4: 132,029,614 (GRCm39)	S203P	probably benign	Het
Rsf1	T	C	7: 97,288,698 (GRCm39)	S192P	probably damaging	Het
Scap	C	T	9: 110,207,758 (GRCm39)	T489I	probably benign	Het
Sost	C	A	11: 101,857,633 (GRCm39)	R56L	possibly damaging	Het
Speer4a3	T	A	5: 26,156,605 (GRCm39)	I125F	probably benign	Het
Spmip10	T	A	18: 56,727,571 (GRCm39)	W90R	possibly damaging	Het
Sptbn4	A	G	7: 27,118,522 (GRCm39)	V264A	probably damaging	Het
Stx3	A	G	19: 11,760,469 (GRCm39)	V236A	probably damaging	Het
Syt2	T	C	1: 134,668,603 (GRCm39)	F5S	probably damaging	Het
Thrap3	T	C	4: 126,060,794 (GRCm39)	D855G	possibly damaging	Het
Ticrr	T	C	7: 79,332,769 (GRCm39)	V874A	possibly damaging	Het
Tmem26	A	G	10: 68,614,563 (GRCm39)	E326G	probably benign	Het
Tspoap1	C	T	11: 87,653,342 (GRCm39)	T136I	possibly damaging	Het
Ttc21b	T	C	2: 66,065,500 (GRCm39)	T425A	probably benign	Het
Ttc27	A	G	17: 75,163,549 (GRCm39)	Y719C	probably damaging	Het
Usp10	C	A	8: 120,675,514 (GRCm39)	S511Y	probably damaging	Het
Vmn1r197	A	G	13: 22,512,792 (GRCm39)	M238V	probably damaging	Het

Other mutations in Tsga13

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01631:Tsga13	APN	6	30,890,501 (GRCm39)	missense	possibly damaging	0.47
IGL02602:Tsga13	APN	6	30,879,212 (GRCm39)	missense	possibly damaging	0.92
R3894:Tsga13	UTSW	6	30,889,198 (GRCm39)	missense	probably benign
R4335:Tsga13	UTSW	6	30,876,980 (GRCm39)	missense	probably damaging	0.97
R4582:Tsga13	UTSW	6	30,879,298 (GRCm39)	missense	probably benign	0.04
R5705:Tsga13	UTSW	6	30,876,951 (GRCm39)	missense	probably damaging	1.00
R6248:Tsga13	UTSW	6	30,874,139 (GRCm39)	missense	probably benign	0.01
R7470:Tsga13	UTSW	6	30,876,981 (GRCm39)	missense	possibly damaging	0.70

Posted On

2015-04-16