Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02492:Zfp983'

295702

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp983

Ensembl Gene

ENSMUSG00000035868

Gene Name

zinc finger protein 983

Synonyms

3110052M02Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.093) question?

Stock #

IGL02492

Quality Score

Status

Chromosome

Chromosomal Location

21869545-21883882 bp(+) (GRCm39)

Type of Mutation

critical splice donor site (1 bp from exon)

DNA Base Change (assembly)

G to A at 21876528 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000039392 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039726]

AlphaFold

E9PUT0

Predicted Effect

probably null
Transcript: ENSMUST00000039726

SMART Domains

Protein: ENSMUSP00000039392
Gene: ENSMUSG00000035868

Domain	Start	End	E-Value	Type
KRAB	13	73	2.42e-22	SMART
ZnF_C2H2	185	207	5.5e-3	SMART
ZnF_C2H2	213	235	5.14e-3	SMART
ZnF_C2H2	241	263	4.54e-4	SMART
ZnF_C2H2	269	291	7.9e-4	SMART
ZnF_C2H2	297	319	2.86e-1	SMART
ZnF_C2H2	325	347	6.88e-4	SMART
ZnF_C2H2	353	375	1.95e-3	SMART
ZnF_C2H2	381	403	1.04e-3	SMART
ZnF_C2H2	409	431	2.79e-4	SMART
ZnF_C2H2	437	459	3.63e-3	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Atm	A	G	9: 53,367,159 (GRCm39)	L2482P	probably damaging	Het
Bcl11b	T	C	12: 107,881,945 (GRCm39)	Y718C	probably damaging	Het
Bltp1	A	G	3: 37,102,262 (GRCm39)	E1320G	probably benign	Het
Ccrl2	A	G	9: 110,884,871 (GRCm39)	I209T	probably benign	Het
Cd200r2	A	G	16: 44,729,903 (GRCm39)	K149R	probably damaging	Het
Cdc45	C	T	16: 18,617,479 (GRCm39)	M200I	probably benign	Het
Col18a1	A	G	10: 76,907,855 (GRCm39)		probably benign	Het
Cops5	T	A	1: 10,097,377 (GRCm39)	T291S	probably benign	Het
Csmd1	C	A	8: 16,052,597 (GRCm39)	V2176F	probably benign	Het
Ctse	C	A	1: 131,595,972 (GRCm39)	S221R	probably damaging	Het
Cxcl3	A	G	5: 90,934,199 (GRCm39)		probably null	Het
Cyp51	C	T	5: 4,154,304 (GRCm39)	V2I	probably benign	Het
Dennd5a	A	G	7: 109,532,844 (GRCm39)	F285L	probably benign	Het
Dst	T	G	1: 34,191,274 (GRCm39)		probably benign	Het
Frzb	A	T	2: 80,254,935 (GRCm39)		probably benign	Het
Gm5070	A	T	3: 95,318,354 (GRCm39)		noncoding transcript	Het
Gm9637	A	G	14: 19,402,182 (GRCm38)		noncoding transcript	Het
Grip1	A	G	10: 119,765,945 (GRCm39)		probably benign	Het
Itga4	C	T	2: 79,086,001 (GRCm39)		probably benign	Het
Ltbp2	A	T	12: 84,856,439 (GRCm39)	I675N	probably damaging	Het
Or4n4b	T	G	14: 50,536,060 (GRCm39)	K235N	probably damaging	Het
Pcdhb20	G	T	18: 37,639,453 (GRCm39)	V660L	probably benign	Het
Prex2	T	G	1: 11,194,069 (GRCm39)	L484R	possibly damaging	Het
Prkg1	A	T	19: 30,701,602 (GRCm39)	V305D	probably damaging	Het
Rab44	A	G	17: 29,365,023 (GRCm39)		probably benign	Het
Smpd4	C	T	16: 17,457,215 (GRCm39)	A391V	probably damaging	Het
Smyd4	T	C	11: 75,294,252 (GRCm39)	L711P	probably benign	Het
Spag16	T	G	1: 69,926,688 (GRCm39)	M261R	probably benign	Het
Steap1	A	G	5: 5,790,561 (GRCm39)	V129A	possibly damaging	Het
Tbcd	A	T	11: 121,387,960 (GRCm39)	I364L	probably benign	Het
Trmt13	C	T	3: 116,376,192 (GRCm39)	D400N	possibly damaging	Het
Vps13a	A	G	19: 16,625,001 (GRCm39)	S2753P	probably damaging	Het
Xirp2	T	G	2: 67,346,511 (GRCm39)	S2917R	probably damaging	Het

Other mutations in Zfp983

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02491:Zfp983	APN	17	21,876,528 (GRCm39)	critical splice donor site	probably null
IGL03145:Zfp983	APN	17	21,877,924 (GRCm39)	missense	probably damaging	0.99
R0257:Zfp983	UTSW	17	21,880,356 (GRCm39)	missense	probably benign	0.35
R1518:Zfp983	UTSW	17	21,881,269 (GRCm39)	missense	probably damaging	1.00
R1925:Zfp983	UTSW	17	21,880,933 (GRCm39)	missense	probably damaging	1.00
R2504:Zfp983	UTSW	17	21,877,883 (GRCm39)	missense	probably damaging	1.00
R3701:Zfp983	UTSW	17	21,880,455 (GRCm39)	missense	probably damaging	1.00
R4308:Zfp983	UTSW	17	21,881,124 (GRCm39)	missense	probably benign	0.05
R5648:Zfp983	UTSW	17	21,877,947 (GRCm39)	missense	probably damaging	1.00
R6029:Zfp983	UTSW	17	21,881,401 (GRCm39)	missense	probably benign	0.03
R6188:Zfp983	UTSW	17	21,877,935 (GRCm39)	missense	probably damaging	1.00
R6662:Zfp983	UTSW	17	21,881,001 (GRCm39)	missense	probably damaging	1.00
R7313:Zfp983	UTSW	17	21,880,413 (GRCm39)	missense	probably damaging	0.97
R7361:Zfp983	UTSW	17	21,880,850 (GRCm39)	missense	probably damaging	1.00
R8710:Zfp983	UTSW	17	21,880,234 (GRCm39)	missense	probably damaging	0.99
R9153:Zfp983	UTSW	17	21,876,522 (GRCm39)	missense	probably benign	0.08
R9285:Zfp983	UTSW	17	21,876,520 (GRCm39)	missense	possibly damaging	0.76

Posted On

2015-04-16