Incidental Mutation 'IGL02508:Gm13101'
ID296417
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm13101
Ensembl Gene ENSMUSG00000078510
Gene Namepredicted gene 13101
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.055) question?
Stock #IGL02508
Quality Score
Status
Chromosome4
Chromosomal Location143964518-143966950 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 143965020 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Aspartic acid at position 378 (N378D)
Ref Sequence ENSEMBL: ENSMUSP00000101389 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000105763]
Predicted Effect probably benign
Transcript: ENSMUST00000105763
AA Change: N378D

PolyPhen 2 Score 0.128 (Sensitivity: 0.93; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000101389
Gene: ENSMUSG00000078510
AA Change: N378D

DomainStartEndE-ValueType
SCOP:d1a4ya_ 210 414 2e-9 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 61 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700061I17Rik T A 3: 117,077,115 noncoding transcript Het
5430419D17Rik A G 7: 131,222,830 E91G probably damaging Het
Adgrv1 A T 13: 81,435,556 probably benign Het
AI429214 T G 8: 36,994,086 D129E probably benign Het
Alx1 G A 10: 103,022,193 T215M probably damaging Het
Arhgap39 A G 15: 76,724,984 *1079Q probably null Het
Brca2 T C 5: 150,543,308 V2179A possibly damaging Het
Celsr1 G A 15: 86,030,617 Q1052* probably null Het
Chd5 A G 4: 152,363,024 E510G probably damaging Het
Cntnap2 A G 6: 46,234,320 D556G probably damaging Het
Cux2 G A 5: 121,860,822 P1352S possibly damaging Het
Cyp4a31 A T 4: 115,571,064 Y319F probably damaging Het
Dcaf12 C T 4: 41,296,310 probably null Het
Dcc C A 18: 71,370,702 A942S probably benign Het
Dyrk1a A T 16: 94,685,183 D463V probably damaging Het
Eln T A 5: 134,704,568 probably benign Het
Fbxl13 A G 5: 21,556,805 probably null Het
Fndc3b T C 3: 27,458,751 Y742C probably damaging Het
Furin G A 7: 80,392,521 T442I probably benign Het
Gli1 T C 10: 127,337,092 Q155R probably benign Het
Glra3 A G 8: 56,085,144 E218G probably benign Het
Grb10 C T 11: 11,946,767 V236M probably damaging Het
Grhl2 T C 15: 37,309,765 probably benign Het
Hgfac A T 5: 35,047,220 M579L probably damaging Het
Ifi202b A T 1: 173,974,772 D165E probably benign Het
Klhl26 A T 8: 70,452,731 D95E probably damaging Het
Klk12 T C 7: 43,769,689 V26A probably benign Het
Lrp2 C T 2: 69,503,430 G1489D probably benign Het
Lrrtm1 A T 6: 77,244,591 S344C probably damaging Het
Lzts1 G A 8: 69,140,848 R36* probably null Het
Mapkap1 T C 2: 34,518,669 probably benign Het
Meis3 T A 7: 16,178,797 probably null Het
Mtmr14 T A 6: 113,240,306 C60S probably damaging Het
Nfkb1 T A 3: 135,590,818 Y789F probably damaging Het
Nup54 G A 5: 92,417,539 Q440* probably null Het
Ogdhl T G 14: 32,345,174 M861R probably damaging Het
Olfr1290 C T 2: 111,489,835 A108T probably damaging Het
Olfr1425 G T 19: 12,073,887 H248Q possibly damaging Het
Olfr156 T C 4: 43,821,289 E24G possibly damaging Het
Olfr692 A T 7: 105,368,536 H61L possibly damaging Het
Olfr810 A G 10: 129,790,791 V266A probably benign Het
Pde6c A G 19: 38,157,500 K412R probably benign Het
Pex5l T C 3: 32,992,902 probably benign Het
Pigr A T 1: 130,850,858 I760L probably benign Het
Prr14l G A 5: 32,830,942 A403V probably benign Het
Prrt3 T C 6: 113,494,307 D968G probably damaging Het
Psmc5 T C 11: 106,263,043 I401T possibly damaging Het
Ralyl T A 3: 14,107,272 probably benign Het
Samd9l T C 6: 3,374,798 E821G probably damaging Het
Serpinb3a T A 1: 107,046,072 I370F probably damaging Het
Setd1a A G 7: 127,797,698 probably benign Het
Slco2a1 T A 9: 103,074,416 F381L probably benign Het
Strada A G 11: 106,168,356 Y199H probably benign Het
Stxbp2 T C 8: 3,632,531 I40T probably damaging Het
Tbx3 T C 5: 119,678,812 V358A possibly damaging Het
Tenm3 A G 8: 48,299,639 L896S probably benign Het
Tmem132a A G 19: 10,858,518 S883P probably damaging Het
Trio A G 15: 27,818,104 I496T possibly damaging Het
Unc79 C T 12: 103,112,276 R1548W probably damaging Het
Unc79 T C 12: 103,112,018 probably benign Het
Vmn2r9 T C 5: 108,848,201 M194V possibly damaging Het
Other mutations in Gm13101
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00484:Gm13101 APN 4 143966614 splice site probably benign
IGL00688:Gm13101 APN 4 143965822 missense possibly damaging 0.62
IGL00690:Gm13101 APN 4 143965822 missense possibly damaging 0.62
IGL00693:Gm13101 APN 4 143965822 missense possibly damaging 0.62
IGL00694:Gm13101 APN 4 143965822 missense possibly damaging 0.62
IGL01412:Gm13101 APN 4 143964995 missense probably damaging 1.00
IGL01781:Gm13101 APN 4 143965729 missense probably benign
IGL02426:Gm13101 APN 4 143966659 missense possibly damaging 0.75
IGL03338:Gm13101 APN 4 143965841 missense probably benign 0.01
IGL03338:Gm13101 APN 4 143966038 missense probably benign 0.03
R0201:Gm13101 UTSW 4 143964890 missense probably damaging 1.00
R0325:Gm13101 UTSW 4 143966740 missense probably damaging 1.00
R0538:Gm13101 UTSW 4 143965083 missense possibly damaging 0.76
R1471:Gm13101 UTSW 4 143964953 missense probably benign 0.25
R1544:Gm13101 UTSW 4 143966062 missense probably benign 0.00
R1891:Gm13101 UTSW 4 143966665 missense probably damaging 1.00
R2012:Gm13101 UTSW 4 143966067 missense probably benign 0.00
R2105:Gm13101 UTSW 4 143965820 missense probably benign
R2939:Gm13101 UTSW 4 143966677 missense probably benign 0.00
R2940:Gm13101 UTSW 4 143966677 missense probably benign 0.00
R3723:Gm13101 UTSW 4 143966681 missense probably benign
R3952:Gm13101 UTSW 4 143965786 nonsense probably null
R4028:Gm13101 UTSW 4 143965784 missense probably benign 0.02
R4029:Gm13101 UTSW 4 143965784 missense probably benign 0.02
R4030:Gm13101 UTSW 4 143965784 missense probably benign 0.02
R5059:Gm13101 UTSW 4 143964995 missense probably damaging 0.99
R5222:Gm13101 UTSW 4 143964792 missense possibly damaging 0.55
R5591:Gm13101 UTSW 4 143964960 missense probably damaging 1.00
R5677:Gm13101 UTSW 4 143965138 missense possibly damaging 0.59
R6021:Gm13101 UTSW 4 143965766 missense probably benign
R6042:Gm13101 UTSW 4 143966061 missense probably benign 0.04
R6155:Gm13101 UTSW 4 143965142 missense probably benign 0.00
R6604:Gm13101 UTSW 4 143965997 missense probably benign 0.02
R6807:Gm13101 UTSW 4 143965011 missense probably damaging 1.00
R7244:Gm13101 UTSW 4 143965885 missense probably benign
Z1088:Gm13101 UTSW 4 143965562 missense probably benign
Posted On2015-04-16