Incidental Mutation 'IGL02513:Vmn2r37'
ID296636
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r37
Ensembl Gene ENSMUSG00000066828
Gene Namevomeronasal 2, receptor 37
SynonymsV2r14
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.085) question?
Stock #IGL02513
Quality Score
Status
Chromosome7
Chromosomal Location9205546-9223653 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 9217935 bp
ZygosityHeterozygous
Amino Acid Change Lysine to Glutamic Acid at position 310 (K310E)
Ref Sequence ENSEMBL: ENSMUSP00000072566 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072787]
Predicted Effect probably benign
Transcript: ENSMUST00000072787
AA Change: K310E

PolyPhen 2 Score 0.138 (Sensitivity: 0.92; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000072566
Gene: ENSMUSG00000066828
AA Change: K310E

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:ANF_receptor 157 469 2.9e-26 PFAM
Pfam:NCD3G 512 563 1.1e-16 PFAM
Pfam:7tm_3 550 783 1.7e-53 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Apob G T 12: 7,992,979 V787F probably benign Het
Atg14 T C 14: 47,548,994 I268V probably benign Het
Atg14 T A 14: 47,545,624 probably benign Het
Atm A T 9: 53,497,262 probably benign Het
Atp5s A T 12: 69,741,045 Y85F probably benign Het
Ccdc9 A G 7: 16,284,509 probably benign Het
Cers6 T C 2: 69,068,669 F217S probably benign Het
Crebbp A C 16: 4,126,605 probably null Het
Csmd1 T A 8: 15,999,869 probably benign Het
Eml1 T A 12: 108,530,312 V609E probably damaging Het
Fam155a T A 8: 9,207,930 D406V probably benign Het
Fryl A G 5: 73,065,293 S204P probably damaging Het
Gpr152 A G 19: 4,142,844 D128G probably damaging Het
Itgal T A 7: 127,328,672 V1013D possibly damaging Het
Kctd18 A G 1: 57,965,400 Y112H probably damaging Het
Kdm4d T A 9: 14,464,554 T3S probably benign Het
Lrp1b C T 2: 41,110,753 probably null Het
Mex3c T A 18: 73,590,289 D484E possibly damaging Het
Nat14 T C 7: 4,924,051 V74A possibly damaging Het
Olfr11 A G 13: 21,639,340 F61S probably damaging Het
Pabpc2 C T 18: 39,775,140 T486I probably benign Het
Pgm1 A G 5: 64,102,946 probably benign Het
Pkn3 T A 2: 30,083,137 I353N probably damaging Het
Rbm44 T A 1: 91,155,538 S594R possibly damaging Het
Rrbp1 C T 2: 143,988,430 A606T possibly damaging Het
Tcof1 A G 18: 60,831,778 V623A possibly damaging Het
Tg A G 15: 66,705,274 E1482G probably benign Het
Uba1 A G X: 20,675,646 T546A probably benign Het
Zbtb38 A T 9: 96,687,073 W653R probably damaging Het
Zdhhc19 A T 16: 32,499,622 I99F probably damaging Het
Zfp236 T C 18: 82,630,114 Y974C probably damaging Het
Other mutations in Vmn2r37
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01346:Vmn2r37 APN 7 9206681 missense probably benign 0.05
IGL01909:Vmn2r37 APN 7 9216033 nonsense probably null
IGL02281:Vmn2r37 APN 7 9217882 missense possibly damaging 0.95
IGL02282:Vmn2r37 APN 7 9206762 missense probably benign 0.19
R0136:Vmn2r37 UTSW 7 9217783 nonsense probably null
R2051:Vmn2r37 UTSW 7 9217793 missense probably damaging 1.00
R2262:Vmn2r37 UTSW 7 9217944 missense probably damaging 0.99
R3158:Vmn2r37 UTSW 7 9217714 missense probably benign 0.03
R4084:Vmn2r37 UTSW 7 9215985 missense probably benign
R4114:Vmn2r37 UTSW 7 9210093 critical splice acceptor site probably null
R5231:Vmn2r37 UTSW 7 9206595 missense possibly damaging 0.94
R5462:Vmn2r37 UTSW 7 9217974 missense probably damaging 1.00
R6437:Vmn2r37 UTSW 7 9217851 missense probably damaging 0.98
R7104:Vmn2r37 UTSW 7 9216046 missense probably damaging 1.00
R7116:Vmn2r37 UTSW 7 9217899 missense probably benign 0.00
Posted On2015-04-16