Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02549:Gm4978'

297957

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm4978

Ensembl Gene

ENSMUSG00000062874

Gene Name

predicted gene 4978

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL02549

Quality Score

Status

Chromosome

Chromosomal Location

69357517-69358317 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 69357641 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000117979 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000034756] [ENSMUST00000123470] [ENSMUST00000134907]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000034756

SMART Domains

Protein: ENSMUSP00000034756
Gene: ENSMUSG00000032231

Domain	Start	End	E-Value	Type
ANX	50	102	5.79e-20	SMART
ANX	122	174	1.5e-27	SMART
ANX	207	259	8.2e-11	SMART
ANX	282	334	1.6e-22	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000071565

SMART Domains

Protein: ENSMUSP00000071496
Gene: ENSMUSG00000062874

Domain	Start	End	E-Value	Type
low complexity region	2	28	N/A	INTRINSIC
Pfam:Ribosomal_L7Ae	123	217	9.7e-26	PFAM
low complexity region	252	263	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000123470

SMART Domains

Protein: ENSMUSP00000122175
Gene: ENSMUSG00000032231

Domain	Start	End	E-Value	Type
ANX	50	102	5.79e-20	SMART
ANX	122	174	1.5e-27	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000134907

SMART Domains

Protein: ENSMUSP00000117979
Gene: ENSMUSG00000032231

Domain	Start	End	E-Value	Type
ANX	50	102	5.79e-20	SMART
ANX	122	174	1.5e-27	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000213736

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca9	T	C	11: 109,992,879 (GRCm39)	E1595G	probably damaging	Het
Adnp2	G	A	18: 80,172,333 (GRCm39)	A692V	probably damaging	Het
Ankk1	A	G	9: 49,329,993 (GRCm39)	S321P	probably damaging	Het
Ankrd11	T	C	8: 123,618,032 (GRCm39)	Y1919C	probably damaging	Het
Atp10a	A	G	7: 58,469,481 (GRCm39)	T1111A	probably benign	Het
Avpr1a	A	T	10: 122,288,069 (GRCm39)	H359L	possibly damaging	Het
C1rl	A	T	6: 124,470,796 (GRCm39)	I35F	possibly damaging	Het
Casp8	G	A	1: 58,872,925 (GRCm39)	C287Y	probably benign	Het
Ccdc88c	A	T	12: 100,895,191 (GRCm39)	S1437T	probably benign	Het
Cd200r1	C	T	16: 44,610,341 (GRCm39)	P150S	probably damaging	Het
Col2a1	G	A	15: 97,875,680 (GRCm39)	R1202C	unknown	Het
Copb1	A	T	7: 113,846,032 (GRCm39)	D179E	probably benign	Het
Cyp2c29	C	T	19: 39,298,229 (GRCm39)	T258I	possibly damaging	Het
Flacc1	T	C	1: 58,698,441 (GRCm39)	T326A	probably benign	Het
Gemin5	T	C	11: 58,025,629 (GRCm39)	Y991C	probably damaging	Het
Gm7732	A	T	17: 21,349,649 (GRCm39)		noncoding transcript	Het
Gucy2f	T	C	X: 140,943,200 (GRCm39)	I478V	probably benign	Het
Herc1	A	G	9: 66,307,183 (GRCm39)	H1001R	probably damaging	Het
Igsf10	A	G	3: 59,236,662 (GRCm39)	V1173A	probably benign	Het
Kansl1l	T	C	1: 66,841,127 (GRCm39)	T58A	probably benign	Het
Kcnk13	A	T	12: 100,028,010 (GRCm39)	K362*	probably null	Het
Lama1	T	G	17: 68,097,830 (GRCm39)	L1737V	possibly damaging	Het
Lama4	A	G	10: 38,936,200 (GRCm39)	N625S	probably benign	Het
Loxl1	A	T	9: 58,200,921 (GRCm39)	C514S	probably damaging	Het
Muc13	A	C	16: 33,628,339 (GRCm39)	E363A	probably damaging	Het
Noxo1	G	T	17: 24,919,145 (GRCm39)	G289V	probably damaging	Het
Nudt7	G	T	8: 114,878,688 (GRCm39)	D239Y	probably damaging	Het
Polr3e	G	T	7: 120,538,982 (GRCm39)	V407F	probably damaging	Het
Pou5f2	T	A	13: 78,173,709 (GRCm39)	L217Q	probably damaging	Het
R3hdm2	A	G	10: 127,320,094 (GRCm39)		probably benign	Het
Rab11fip3	A	C	17: 26,213,294 (GRCm39)	N793K	probably damaging	Het
Ranbp3l	A	G	15: 8,997,925 (GRCm39)	R6G	possibly damaging	Het
Slco1a6	T	A	6: 142,042,141 (GRCm39)		probably benign	Het
Sspo	A	G	6: 48,428,707 (GRCm39)	E374G	possibly damaging	Het
Tg	T	C	15: 66,711,210 (GRCm39)	Y991H	probably damaging	Het
Tnc	A	G	4: 63,933,309 (GRCm39)	Y652H	probably damaging	Het
Trpc4	G	A	3: 54,129,770 (GRCm39)	V179I	possibly damaging	Het
Xirp2	A	G	2: 67,343,446 (GRCm39)	T1896A	probably benign	Het
Zfhx3	T	C	8: 109,527,141 (GRCm39)	Y1013H	probably damaging	Het

Other mutations in Gm4978

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL01717:Gm4978	APN	9	69,358,155 (GRCm39)	unclassified	probably benign
IGL02661:Gm4978	APN	9	69,358,180 (GRCm39)	unclassified	probably benign
R4940:Gm4978	UTSW	9	69,358,154 (GRCm39)	unclassified	probably benign
Y5404:Gm4978	UTSW	9	69,357,984 (GRCm39)	unclassified	probably benign
Y5407:Gm4978	UTSW	9	69,357,984 (GRCm39)	unclassified	probably benign

Posted On

2015-04-16