Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02562:Gm4953'

298686

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm4953

Ensembl Gene

ENSMUSG00000061992

Gene Name

predicted pseudogene 4953

Synonyms

Accession Numbers

Essential gene?

Probably essential (E-score: 0.834) question?

Stock #

IGL02562

Quality Score

Status

Chromosome

Chromosomal Location

158995730-158996212 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

A to T at 158996077 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000077309

SMART Domains

Protein: ENSMUSP00000076538
Gene: ENSMUSG00000061992

Domain	Start	End	E-Value	Type
Pfam:Mt_ATP-synt_D	3	160	3.3e-65	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000195279

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrl4	T	C	3: 151,144,949 (GRCm39)	C33R	probably damaging	Het
Aifm3	A	G	16: 17,324,126 (GRCm39)	N562S	probably benign	Het
Akap14	G	A	X: 36,427,441 (GRCm39)	T98M	possibly damaging	Het
Atp7b	T	G	8: 22,518,101 (GRCm39)	T234P	probably benign	Het
Atp8b1	T	A	18: 64,715,057 (GRCm39)	Q65L	probably benign	Het
Bclaf3	T	C	X: 158,349,434 (GRCm39)	S600P	probably benign	Het
Cdc45	C	T	16: 18,617,479 (GRCm39)	M200I	probably benign	Het
Col4a5	A	G	X: 140,439,671 (GRCm39)		probably benign	Het
Gigyf2	A	G	1: 87,335,097 (GRCm39)	D120G	probably benign	Het
Hip1r	G	T	5: 124,129,586 (GRCm39)		probably benign	Het
Itga2	A	G	13: 114,973,106 (GRCm39)		probably benign	Het
Itga3	T	C	11: 94,959,619 (GRCm39)	T85A	probably benign	Het
Loxl1	A	G	9: 58,196,199 (GRCm39)	S607P	probably damaging	Het
Marchf2	G	A	17: 33,915,048 (GRCm39)	T182I	probably damaging	Het
Mbd1	T	C	18: 74,409,993 (GRCm39)	S386P	probably benign	Het
Meis2	C	A	2: 115,879,627 (GRCm39)	G231V	probably damaging	Het
Myo1h	A	G	5: 114,496,053 (GRCm39)	K774E	probably benign	Het
Or10a2	C	A	7: 106,673,769 (GRCm39)	H245N	probably benign	Het
Or1e26	T	C	11: 73,480,237 (GRCm39)	N109S	probably benign	Het
Or2l5	A	T	16: 19,333,714 (GRCm39)	I224N	possibly damaging	Het
Or51ag1	G	T	7: 103,155,423 (GRCm39)	C243*	probably null	Het
Or8u9	T	G	2: 86,001,384 (GRCm39)	Y259S	probably damaging	Het
Pcm1	T	A	8: 41,778,405 (GRCm39)	D1813E	probably damaging	Het
Pdcl2	A	G	5: 76,467,038 (GRCm39)	Y52H	probably damaging	Het
Piezo1	T	C	8: 123,223,502 (GRCm39)	T816A	probably benign	Het
Ptpn13	T	G	5: 103,710,157 (GRCm39)	L1564R	probably damaging	Het
Pwwp3a	A	G	10: 80,074,729 (GRCm39)	D438G	probably damaging	Het
S2bpcox16	T	C	12: 81,557,616 (GRCm39)	D63G	probably damaging	Het
Slc7a2	T	A	8: 41,368,057 (GRCm39)	M607K	probably damaging	Het
Snrpa	T	A	7: 26,891,123 (GRCm39)	K116M	probably damaging	Het
Spon1	A	G	7: 113,635,996 (GRCm39)	S737G	probably benign	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
Sspo	A	G	6: 48,467,056 (GRCm39)		probably null	Het
Tubb4a	C	A	17: 57,388,163 (GRCm39)	E288*	probably null	Het
Vmn2r87	A	T	10: 130,314,513 (GRCm39)	C358S	probably damaging	Het

Other mutations in Gm4953

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL02941:Gm4953	APN	1	158,995,963 (GRCm39)	unclassified	noncoding transcript
R1976:Gm4953	UTSW	1	158,995,923 (GRCm39)	unclassified	noncoding transcript
R4802:Gm4953	UTSW	1	158,995,988 (GRCm39)	unclassified	noncoding transcript
R4910:Gm4953	UTSW	1	158,995,929 (GRCm39)	unclassified	noncoding transcript
R4911:Gm4953	UTSW	1	158,995,929 (GRCm39)	unclassified	noncoding transcript

Posted On

2015-04-16