Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02563:Zfp319'

298725

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp319

Ensembl Gene

ENSMUSG00000046556

Gene Name

zinc finger protein 319

Synonyms

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.256) question?

Stock #

IGL02563

Quality Score

Status

Chromosome

Chromosomal Location

96052759-96058439 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 96050362 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000148526 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057717] [ENSMUST00000098480] [ENSMUST00000135142] [ENSMUST00000161029] [ENSMUST00000162294] [ENSMUST00000212056]

AlphaFold

Q9ERR8

Predicted Effect

probably benign
Transcript: ENSMUST00000057717

SMART Domains

Protein: ENSMUSP00000053397
Gene: ENSMUSG00000046556

Domain	Start	End	E-Value	Type
low complexity region	6	29	N/A	INTRINSIC
low complexity region	53	64	N/A	INTRINSIC
Blast:ZnF_C2H2	75	99	6e-7	BLAST
ZnF_C2H2	103	123	7.57e1	SMART
ZnF_C2H2	131	153	8.67e-1	SMART
low complexity region	168	189	N/A	INTRINSIC
ZnF_C2H2	201	223	9.73e-4	SMART
ZnF_C2H2	229	251	1.47e-3	SMART
ZnF_C2H2	257	279	1.12e-3	SMART
ZnF_C2H2	314	336	6.42e-4	SMART
ZnF_C2H2	342	364	1.2e-3	SMART
ZnF_C2H2	370	392	8.81e-2	SMART
ZnF_C2H2	398	418	2.75e1	SMART
ZnF_C2H2	427	449	1.84e-4	SMART
ZnF_C2H2	457	477	1.27e2	SMART
ZnF_C2H2	485	507	2.79e-4	SMART
ZnF_C2H2	513	535	6.42e-4	SMART
ZnF_C2H2	541	563	4.11e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000098480

Predicted Effect

probably benign
Transcript: ENSMUST00000135142

Predicted Effect

probably benign
Transcript: ENSMUST00000153991

Predicted Effect

probably benign
Transcript: ENSMUST00000161029

Predicted Effect

probably benign
Transcript: ENSMUST00000162294

Predicted Effect

probably benign
Transcript: ENSMUST00000212056

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 50 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930402F06Rik	A	T	2: 35,270,410 (GRCm39)	V97E	probably damaging	Het
Abhd16a	C	T	17: 35,320,221 (GRCm39)	T362M	probably damaging	Het
Adam23	T	G	1: 63,607,136 (GRCm39)		probably benign	Het
Apeh	C	A	9: 107,970,908 (GRCm39)	R87L	possibly damaging	Het
Arid3a	T	A	10: 79,786,717 (GRCm39)	M490K	probably damaging	Het
Atp6v1b1	T	A	6: 83,732,433 (GRCm39)	V251D	probably benign	Het
Cog8	C	T	8: 107,783,055 (GRCm39)	R78Q	possibly damaging	Het
Cyld	T	C	8: 89,462,522 (GRCm39)	I701T	probably damaging	Het
Dmgdh	A	G	13: 93,811,047 (GRCm39)		probably benign	Het
Dnm1	T	C	2: 32,205,931 (GRCm39)		probably null	Het
Dop1b	T	A	16: 93,574,293 (GRCm39)	V2D	probably damaging	Het
Dusp22	A	T	13: 30,889,628 (GRCm39)	S70C	possibly damaging	Het
Dync2h1	T	C	9: 7,035,700 (GRCm39)	Q3415R	possibly damaging	Het
Dysf	T	C	6: 84,163,498 (GRCm39)		probably benign	Het
Fam114a1	G	A	5: 65,163,491 (GRCm39)		probably null	Het
Fam20a	T	A	11: 109,568,620 (GRCm39)	Q302L	possibly damaging	Het
Fancm	T	A	12: 65,139,236 (GRCm39)	L374H	probably damaging	Het
Fcgbpl1	G	A	7: 27,857,317 (GRCm39)	E2222K	probably benign	Het
Fgf17	G	A	14: 70,874,178 (GRCm39)	Q204*	probably null	Het
Gap43	T	C	16: 42,112,495 (GRCm39)	T89A	probably benign	Het
Gm5069	A	G	1: 180,155,464 (GRCm39)		probably benign	Het
Gm9913	C	T	2: 125,348,254 (GRCm39)		probably benign	Het
Gpr174	T	C	X: 106,336,854 (GRCm39)	L222P	probably benign	Het
Grid2	A	T	6: 64,322,857 (GRCm39)	Q619L	possibly damaging	Het
Hoxc13	A	G	15: 102,830,233 (GRCm39)	D204G	possibly damaging	Het
Itgav	T	C	2: 83,601,580 (GRCm39)	V317A	probably benign	Het
Keg1	A	T	19: 12,696,521 (GRCm39)	N288I	probably damaging	Het
Ksr1	C	T	11: 78,935,684 (GRCm39)	V234I	possibly damaging	Het
Lrp1	T	A	10: 127,387,555 (GRCm39)	D3365V	probably damaging	Het
Luc7l3	A	T	11: 94,190,894 (GRCm39)		probably null	Het
Mta2	T	C	19: 8,925,415 (GRCm39)	I348T	probably benign	Het
Nphp4	A	G	4: 152,640,677 (GRCm39)	I1015V	probably benign	Het
Nup214	C	T	2: 31,867,872 (GRCm39)	S113F	probably damaging	Het
Or4f7	T	C	2: 111,644,162 (GRCm39)	K303R	probably benign	Het
Pabpn1l	T	A	8: 123,347,122 (GRCm39)	T228S	probably damaging	Het
Paxx	T	C	2: 25,349,674 (GRCm39)	*206W	probably null	Het
Pcdhb10	A	G	18: 37,546,126 (GRCm39)	T401A	probably benign	Het
Ppp1r3a	A	C	6: 14,719,761 (GRCm39)	D384E	probably benign	Het
Rif1	T	C	2: 51,967,077 (GRCm39)	V122A	probably damaging	Het
Scn4b	T	C	9: 45,057,980 (GRCm39)	L24P	probably damaging	Het
Sec22c	T	C	9: 121,513,716 (GRCm39)		probably benign	Het
Sh3rf2	A	G	18: 42,289,207 (GRCm39)	D676G	probably damaging	Het
Slc20a1	A	G	2: 129,049,604 (GRCm39)	T289A	probably benign	Het
Tekt2	T	C	4: 126,218,418 (GRCm39)	D84G	possibly damaging	Het
Tgfbr2	T	A	9: 115,959,066 (GRCm39)	N116I	probably benign	Het
Tmem196	A	G	12: 119,910,209 (GRCm39)	M1V	probably null	Het
Tnn	A	G	1: 159,942,123 (GRCm39)	V1125A	probably damaging	Het
Vmn2r51	A	T	7: 9,834,243 (GRCm39)	M265K	probably benign	Het
Zfp65	A	T	13: 67,856,184 (GRCm39)	V365E	possibly damaging	Het
Zp3	T	A	5: 136,016,464 (GRCm39)		probably null	Het

Other mutations in Zfp319

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01611:Zfp319	APN	8	96,055,540 (GRCm39)	missense	probably benign	0.11
IGL02478:Zfp319	APN	8	96,055,721 (GRCm39)	missense	possibly damaging	0.95
IGL02622:Zfp319	APN	8	96,055,589 (GRCm39)	missense	probably damaging	0.97
IGL02945:Zfp319	APN	8	96,050,446 (GRCm39)	unclassified	probably benign
Lanky	UTSW	8	96,054,733 (GRCm39)	frame shift	probably null
R0894:Zfp319	UTSW	8	96,056,250 (GRCm39)	unclassified	probably benign
R1898:Zfp319	UTSW	8	96,055,417 (GRCm39)	missense	probably damaging	1.00
R1937:Zfp319	UTSW	8	96,055,199 (GRCm39)	missense	probably damaging	1.00
R2127:Zfp319	UTSW	8	96,050,391 (GRCm39)	unclassified	probably benign
R2157:Zfp319	UTSW	8	96,054,659 (GRCm39)	missense	probably damaging	1.00
R2256:Zfp319	UTSW	8	96,055,129 (GRCm39)	missense	possibly damaging	0.47
R3547:Zfp319	UTSW	8	96,055,445 (GRCm39)	missense	probably damaging	0.96
R4665:Zfp319	UTSW	8	96,052,201 (GRCm39)	unclassified	probably benign
R5174:Zfp319	UTSW	8	96,054,797 (GRCm39)	splice site	probably null
R5249:Zfp319	UTSW	8	96,055,099 (GRCm39)	missense	probably benign	0.00
R5478:Zfp319	UTSW	8	96,052,193 (GRCm39)	unclassified	probably benign
R5623:Zfp319	UTSW	8	96,052,199 (GRCm39)	unclassified	probably benign
R6165:Zfp319	UTSW	8	96,054,733 (GRCm39)	frame shift	probably null
R7175:Zfp319	UTSW	8	96,055,410 (GRCm39)	missense	probably damaging	1.00
R7271:Zfp319	UTSW	8	96,058,471 (GRCm39)	unclassified	probably benign
R8303:Zfp319	UTSW	8	96,055,765 (GRCm39)	missense	probably damaging	1.00
R8734:Zfp319	UTSW	8	96,054,938 (GRCm39)	missense	possibly damaging	0.51
R9443:Zfp319	UTSW	8	96,054,922 (GRCm39)	missense	probably benign	0.00
R9550:Zfp319	UTSW	8	96,055,025 (GRCm39)	missense	probably benign	0.06

Posted On

2015-04-16