Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02586:Armc1'

299568

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Armc1

Ensembl Gene

ENSMUSG00000027599

Gene Name

armadillo repeat containing 1

Synonyms

Arcp, 2310016N05Rik, 2900046P06Rik, C330014L16Rik, 3110009G21Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.178) question?

Stock #

IGL02586

Quality Score

Status

Chromosome

Chromosomal Location

19185566-19217229 bp(-) (GRCm39)

Type of Mutation

utr 3 prime

DNA Base Change (assembly)

G to T at 19188192 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000029125 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000029125]

AlphaFold

Q9D7A8

Predicted Effect

probably benign
Transcript: ENSMUST00000029125

SMART Domains

Protein: ENSMUSP00000029125
Gene: ENSMUSG00000027599

Domain	Start	End	E-Value	Type
Pfam:Arm	27	68	1.1e-6	PFAM
SCOP:d1fvqa_	142	203	6e-10	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca13	A	G	11: 9,243,983 (GRCm39)	I1949V	possibly damaging	Het
Anapc2	T	A	2: 25,175,108 (GRCm39)	M742K	probably benign	Het
Arhgef12	T	A	9: 42,917,200 (GRCm39)	K380*	probably null	Het
Bltp1	G	A	3: 37,098,757 (GRCm39)	W4626*	probably null	Het
Diaph3	A	T	14: 87,223,512 (GRCm39)	L323*	probably null	Het
Fbxo11	C	T	17: 88,318,711 (GRCm39)		probably benign	Het
Flywch1	C	T	17: 23,974,676 (GRCm39)	A655T	probably benign	Het
Frmpd1	A	G	4: 45,285,160 (GRCm39)	D1327G	probably damaging	Het
Ggact	G	A	14: 123,128,942 (GRCm39)	T91I	possibly damaging	Het
Gm10250	T	A	15: 5,150,412 (GRCm39)		probably benign	Het
Gsdmc4	T	C	15: 63,765,641 (GRCm39)	S303G	probably damaging	Het
Helt	T	C	8: 46,746,276 (GRCm39)	E15G	probably damaging	Het
Kcnf1	T	A	12: 17,226,144 (GRCm39)	S26C	probably benign	Het
Lilra6	T	C	7: 3,911,819 (GRCm39)	T280A	probably benign	Het
Lipo3	A	T	19: 33,559,539 (GRCm39)	D110E	possibly damaging	Het
Mepe	C	A	5: 104,485,316 (GRCm39)	T152N	probably benign	Het
Nr2f1	C	A	13: 78,343,275 (GRCm39)		probably benign	Het
Or5ak24	T	C	2: 85,260,810 (GRCm39)	D121G	possibly damaging	Het
Or6c214	A	G	10: 129,590,524 (GRCm39)	I265T	possibly damaging	Het
Peg3	T	C	7: 6,713,068 (GRCm39)	D718G	probably benign	Het
Phf2	A	T	13: 48,967,334 (GRCm39)		probably benign	Het
Pigc	A	T	1: 161,798,503 (GRCm39)	I162F	probably benign	Het
Raf1	A	G	6: 115,597,267 (GRCm39)	L11P	probably damaging	Het
Rlf	T	C	4: 121,007,261 (GRCm39)	Y573C	probably damaging	Het
Rnf123	G	A	9: 107,945,501 (GRCm39)	R390*	probably null	Het
Rnf149	T	G	1: 39,604,296 (GRCm39)	Q189P	probably benign	Het
Slc11a1	T	C	1: 74,424,291 (GRCm39)		probably benign	Het
Slc22a12	C	T	19: 6,590,487 (GRCm39)	M234I	probably benign	Het
Slc28a1	A	T	7: 80,814,167 (GRCm39)	I455F	probably benign	Het
Slc35f5	T	G	1: 125,512,273 (GRCm39)	L358V	probably damaging	Het
Slc47a1	A	T	11: 61,235,147 (GRCm39)	V562D	probably benign	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
Ushbp1	T	C	8: 71,841,394 (GRCm39)		probably benign	Het
Vmn1r88	T	A	7: 12,911,735 (GRCm39)	Y30*	probably null	Het
Vmn2r27	A	T	6: 124,201,434 (GRCm39)	Y174*	probably null	Het
Wwox	T	C	8: 115,438,947 (GRCm39)	Y338H	possibly damaging	Het
Zfp518a	G	A	19: 40,903,061 (GRCm39)	G997R	probably damaging	Het
Zup1	A	T	10: 33,811,261 (GRCm39)		probably benign	Het

Other mutations in Armc1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00837:Armc1	APN	3	19,198,584 (GRCm39)	missense	probably benign	0.21
IGL01453:Armc1	APN	3	19,198,594 (GRCm39)	missense	probably benign	0.03
IGL02012:Armc1	APN	3	19,211,701 (GRCm39)	missense	possibly damaging	0.57
R0512:Armc1	UTSW	3	19,203,659 (GRCm39)	missense	possibly damaging	0.87
R1694:Armc1	UTSW	3	19,189,050 (GRCm39)	missense	possibly damaging	0.81
R1878:Armc1	UTSW	3	19,211,708 (GRCm39)	missense	probably damaging	1.00
R1881:Armc1	UTSW	3	19,189,060 (GRCm39)	missense	possibly damaging	0.76
R2191:Armc1	UTSW	3	19,188,225 (GRCm39)	missense	probably damaging	1.00
R2264:Armc1	UTSW	3	19,189,033 (GRCm39)	missense	probably damaging	1.00
R2403:Armc1	UTSW	3	19,211,840 (GRCm39)	start gained	probably benign
R2969:Armc1	UTSW	3	19,189,024 (GRCm39)	missense	probably benign
R3861:Armc1	UTSW	3	19,189,196 (GRCm39)	missense	probably damaging	1.00
R4296:Armc1	UTSW	3	19,203,680 (GRCm39)	missense	probably damaging	0.99
R6753:Armc1	UTSW	3	19,198,562 (GRCm39)	missense	possibly damaging	0.86
R6891:Armc1	UTSW	3	19,189,205 (GRCm39)	missense	probably damaging	1.00
R7837:Armc1	UTSW	3	19,198,633 (GRCm39)	missense	probably benign	0.01
R8373:Armc1	UTSW	3	19,203,731 (GRCm39)	missense	probably damaging	1.00
R8743:Armc1	UTSW	3	19,211,700 (GRCm39)	missense	probably benign	0.19
Z1088:Armc1	UTSW	3	19,203,671 (GRCm39)	missense	probably damaging	1.00
Z1177:Armc1	UTSW	3	19,203,738 (GRCm39)	missense	probably benign	0.08

Posted On

2015-04-16