Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02588:Retnlg'

299595

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Retnlg

Ensembl Gene

ENSMUSG00000022651

Gene Name

resistin like gamma

Synonyms

Xcp1, Fizz3, Relmg

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.052) question?

Stock #

IGL02588

Quality Score

Status

Chromosome

Chromosomal Location

48692984-48694859 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 48693255 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 11 (T11A)

Ref Sequence

ENSEMBL: ENSMUSP00000070238 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000065666]

AlphaFold

Q8K426

Predicted Effect

probably benign
Transcript: ENSMUST00000065666
AA Change: T11A

PolyPhen 2 Score 0.070 (Sensitivity: 0.94; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000070238
Gene: ENSMUSG00000022651
AA Change: T11A

Domain	Start	End	E-Value	Type
low complexity region	9	21	N/A	INTRINSIC
Pfam:Resistin	29	116	1.6e-38	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 46 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Akap6	G	A	12: 52,933,282 (GRCm39)	W258*	probably null	Het
Ankmy2	T	C	12: 36,226,685 (GRCm39)		probably benign	Het
Arhgap26	G	T	18: 38,734,670 (GRCm39)		probably benign	Het
Aspscr1	A	G	11: 120,568,357 (GRCm39)	D60G	possibly damaging	Het
Cdh15	C	A	8: 123,583,291 (GRCm39)	Y31*	probably null	Het
Cnih3	A	G	1: 181,237,269 (GRCm39)	R76G	probably benign	Het
Cplx1	C	A	5: 108,673,289 (GRCm39)	R44L	possibly damaging	Het
Dhx57	T	A	17: 80,576,300 (GRCm39)	I597F	probably damaging	Het
Dnah17	G	T	11: 117,916,479 (GRCm39)	F4231L	possibly damaging	Het
Dst	T	G	1: 34,156,565 (GRCm39)	L173R	probably damaging	Het
Fezf2	A	T	14: 12,343,687 (GRCm38)	Y353N	probably damaging	Het
Ghrhr	T	A	6: 55,360,395 (GRCm39)	L247Q	probably damaging	Het
Gm10912	C	T	2: 103,897,197 (GRCm39)		probably benign	Het
Gpcpd1	A	T	2: 132,376,673 (GRCm39)	L541H	probably damaging	Het
Gpld1	C	T	13: 25,127,682 (GRCm39)	T28I	probably damaging	Het
Lmf2	A	T	15: 89,239,609 (GRCm39)		probably null	Het
Lratd2	T	C	15: 60,694,999 (GRCm39)	D249G	probably damaging	Het
Mex3c	A	G	18: 73,723,116 (GRCm39)	N403S	probably damaging	Het
Nlrp1b	A	T	11: 71,073,105 (GRCm39)	L246*	probably null	Het
Nlrp2	A	T	7: 5,330,551 (GRCm39)	L615*	probably null	Het
Nlrp4c	A	T	7: 6,087,647 (GRCm39)	D760V	probably benign	Het
Nlrp4g	T	C	9: 124,348,843 (GRCm38)		noncoding transcript	Het
Nr2f1	C	A	13: 78,343,275 (GRCm39)		probably benign	Het
Nuggc	T	A	14: 65,855,226 (GRCm39)		probably benign	Het
Or4c122	T	C	2: 89,080,042 (GRCm39)		probably benign	Het
Or52d1	C	T	7: 103,756,260 (GRCm39)	T258I	possibly damaging	Het
Papolg	T	A	11: 23,840,252 (GRCm39)	I75F	probably damaging	Het
Pcdhgc5	A	G	18: 37,955,003 (GRCm39)	Y759C	probably damaging	Het
Pdp2	A	G	8: 105,321,536 (GRCm39)	K462E	possibly damaging	Het
Plod1	A	T	4: 147,997,747 (GRCm39)	L654*	probably null	Het
Ppp4r3b	G	T	11: 29,148,853 (GRCm39)	G25*	probably null	Het
Ptch1	T	C	13: 63,659,732 (GRCm39)	D1307G	probably benign	Het
Ranbp17	A	G	11: 33,167,361 (GRCm39)	V1034A	probably benign	Het
Rbl2	T	A	8: 91,813,712 (GRCm39)	L319Q	probably damaging	Het
Rfc3	A	T	5: 151,566,381 (GRCm39)	F356Y	possibly damaging	Het
Rnf213	G	T	11: 119,307,362 (GRCm39)	C674F	probably benign	Het
Shcbp1l	A	G	1: 153,304,411 (GRCm39)	K157E	probably benign	Het
Slc22a17	A	G	14: 55,145,451 (GRCm39)	C233R	probably damaging	Het
Slc38a9	A	G	13: 112,834,511 (GRCm39)		probably null	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
St14	C	A	9: 31,001,329 (GRCm39)		probably benign	Het
Sympk	G	A	7: 18,776,550 (GRCm39)	V481M	probably benign	Het
Timeless	T	A	10: 128,079,203 (GRCm39)	L350Q	probably damaging	Het
Tnfrsf1a	A	G	6: 125,337,729 (GRCm39)	I229V	probably benign	Het
Ugt3a1	A	T	15: 9,361,542 (GRCm39)	H106L	probably benign	Het
Zbtb45	A	T	7: 12,740,204 (GRCm39)	C470*	probably null	Het

Other mutations in Retnlg

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00985:Retnlg	APN	16	48,694,688 (GRCm39)	missense	possibly damaging	0.89
IGL02500:Retnlg	APN	16	48,693,323 (GRCm39)	missense	probably benign	0.16
IGL03206:Retnlg	APN	16	48,694,655 (GRCm39)	missense	probably damaging	1.00
R1165:Retnlg	UTSW	16	48,694,017 (GRCm39)	missense	possibly damaging	0.76
R1751:Retnlg	UTSW	16	48,693,991 (GRCm39)	missense	possibly damaging	0.54
R1767:Retnlg	UTSW	16	48,693,991 (GRCm39)	missense	possibly damaging	0.54
R1796:Retnlg	UTSW	16	48,694,610 (GRCm39)	missense	probably benign	0.06
R2037:Retnlg	UTSW	16	48,694,615 (GRCm39)	missense	probably damaging	1.00
R4780:Retnlg	UTSW	16	48,694,697 (GRCm39)	missense	possibly damaging	0.74
R7298:Retnlg	UTSW	16	48,693,237 (GRCm39)	missense	probably benign
R7983:Retnlg	UTSW	16	48,693,261 (GRCm39)	missense	probably damaging	0.98
R8991:Retnlg	UTSW	16	48,694,038 (GRCm39)	missense	possibly damaging	0.50
R9140:Retnlg	UTSW	16	48,693,288 (GRCm39)	missense	possibly damaging	0.85

Posted On

2015-04-16