Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02596:Erich2'

299844

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Erich2

Ensembl Gene

ENSMUSG00000075302

Gene Name

glutamate rich 2

Synonyms

4933404M02Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.073) question?

Stock #

IGL02596

Quality Score

Status

Chromosome

Chromosomal Location

70339163-70371228 bp(+) (GRCm39)

Type of Mutation

intron

DNA Base Change (assembly)

A to G at 70343147 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000122481 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000100041] [ENSMUST00000134607]

AlphaFold

E9Q1A6

Predicted Effect

unknown
Transcript: ENSMUST00000100041
AA Change: T185A

SMART Domains

Protein: ENSMUSP00000097619
Gene: ENSMUSG00000075302
AA Change: T185A

Domain	Start	End	E-Value	Type
low complexity region	63	90	N/A	INTRINSIC
low complexity region	93	110	N/A	INTRINSIC
low complexity region	268	279	N/A	INTRINSIC
low complexity region	347	365	N/A	INTRINSIC
low complexity region	428	463	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000123137

Predicted Effect

probably benign
Transcript: ENSMUST00000134607

SMART Domains

Protein: ENSMUSP00000122481
Gene: ENSMUSG00000075302

Domain	Start	End	E-Value	Type
low complexity region	63	90	N/A	INTRINSIC
low complexity region	93	110	N/A	INTRINSIC
low complexity region	242	253	N/A	INTRINSIC
low complexity region	321	339	N/A	INTRINSIC
low complexity region	402	437	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000136967

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000150702

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000151851

Predicted Effect

unknown
Transcript: ENSMUST00000153121
AA Change: T53A

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310002L09Rik	T	G	4: 73,868,904 (GRCm39)	Q11H	possibly damaging	Het
Armcx5	T	A	X: 134,647,268 (GRCm39)	I448K	probably damaging	Het
Atp4b	T	A	8: 13,443,471 (GRCm39)	Y69F	possibly damaging	Het
Ccdc7b	T	A	8: 129,798,959 (GRCm39)	V12E	probably benign	Het
Cdc5l	C	A	17: 45,735,530 (GRCm39)		probably benign	Het
Clptm1l	C	T	13: 73,761,785 (GRCm39)	R330C	probably benign	Het
Cpq	C	T	15: 33,213,160 (GRCm39)	R60W	probably damaging	Het
Cpvl	T	C	6: 53,908,995 (GRCm39)	Y256C	probably damaging	Het
Cryzl2	A	T	1: 157,292,539 (GRCm39)	D107V	probably damaging	Het
Cyp2e1	G	A	7: 140,350,031 (GRCm39)	V239M	probably damaging	Het
Cyp2j7	T	A	4: 96,103,659 (GRCm39)	D292V	possibly damaging	Het
Dcaf1	A	G	9: 106,740,220 (GRCm39)	Y1202C	probably damaging	Het
Dnah3	T	C	7: 119,538,137 (GRCm39)	N3616S	probably benign	Het
Enam	A	G	5: 88,650,885 (GRCm39)	D723G	probably benign	Het
Eps8l1	G	A	7: 4,473,871 (GRCm39)	R226H	probably damaging	Het
Esyt3	A	C	9: 99,210,068 (GRCm39)	L271V	probably benign	Het
Fer1l4	T	C	2: 155,881,052 (GRCm39)	N838S	probably benign	Het
Gad1	T	C	2: 70,425,028 (GRCm39)	Y441H	probably damaging	Het
Gja1	G	T	10: 56,264,348 (GRCm39)	V236F	possibly damaging	Het
Gpr156	T	C	16: 37,799,086 (GRCm39)	I100T	probably benign	Het
Hace1	A	G	10: 45,576,736 (GRCm39)	T803A	possibly damaging	Het
Jagn1	G	A	6: 113,424,562 (GRCm39)	V145I	probably benign	Het
Kdm4b	C	A	17: 56,706,706 (GRCm39)	T899K	probably benign	Het
Klk1b8	G	A	7: 43,602,187 (GRCm39)	V40M	probably damaging	Het
Lyst	G	A	13: 13,835,541 (GRCm39)	C1741Y	probably benign	Het
Mast1	G	T	8: 85,644,400 (GRCm39)	A843E	probably benign	Het
Mbd1	T	A	18: 74,409,868 (GRCm39)		probably benign	Het
Mdga1	A	G	17: 30,051,379 (GRCm39)		probably benign	Het
Mlh3	A	G	12: 85,287,732 (GRCm39)		probably null	Het
Or10ag53	C	A	2: 87,082,473 (GRCm39)	T64K	probably damaging	Het
Or5b109	A	T	19: 13,211,763 (GRCm39)	I50F	probably damaging	Het
Pwp1	A	G	10: 85,707,882 (GRCm39)		probably null	Het
Rbm12	C	T	2: 155,937,480 (GRCm39)		probably benign	Het
Slc12a7	T	A	13: 73,933,242 (GRCm39)	V100E	probably benign	Het
Spata31e2	T	A	1: 26,723,083 (GRCm39)	H699L	probably benign	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
Tgfb1i1	T	A	7: 127,848,068 (GRCm39)	M1K	probably null	Het
Tubgcp6	T	A	15: 88,985,117 (GRCm39)	E1657V	probably damaging	Het
Zfp770	A	G	2: 114,026,308 (GRCm39)	V587A	probably benign	Het
Zxdc	A	G	6: 90,350,691 (GRCm39)		probably null	Het

Other mutations in Erich2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02945:Erich2	APN	2	70,364,738 (GRCm39)	missense	probably damaging	0.99
IGL03227:Erich2	APN	2	70,343,114 (GRCm39)	intron	probably benign
IGL03055:Erich2	UTSW	2	70,339,529 (GRCm39)	missense	possibly damaging	0.83
R0503:Erich2	UTSW	2	70,371,119 (GRCm39)	missense	unknown
R0503:Erich2	UTSW	2	70,340,043 (GRCm39)	missense	probably damaging	0.96
R1134:Erich2	UTSW	2	70,366,535 (GRCm39)	nonsense	probably null
R1496:Erich2	UTSW	2	70,343,117 (GRCm39)	intron	probably benign
R3689:Erich2	UTSW	2	70,371,097 (GRCm39)	missense	unknown
R4027:Erich2	UTSW	2	70,343,134 (GRCm39)	intron	probably benign
R4833:Erich2	UTSW	2	70,364,636 (GRCm39)	missense	possibly damaging	0.92
R6284:Erich2	UTSW	2	70,370,028 (GRCm39)	missense	probably damaging	1.00
R6884:Erich2	UTSW	2	70,339,505 (GRCm39)	missense	possibly damaging	0.94
R7485:Erich2	UTSW	2	70,362,109 (GRCm39)	missense	probably damaging	1.00
R7497:Erich2	UTSW	2	70,364,666 (GRCm39)	missense	probably damaging	1.00
R8356:Erich2	UTSW	2	70,357,873 (GRCm39)	splice site	probably null
R8998:Erich2	UTSW	2	70,361,964 (GRCm39)	unclassified	probably benign
R9698:Erich2	UTSW	2	70,371,055 (GRCm39)	missense	unknown
Z1176:Erich2	UTSW	2	70,339,458 (GRCm39)	missense	possibly damaging	0.81

Posted On

2015-04-16