Incidental Mutation 'IGL02603:Gm5286'
ID300149
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5286
Ensembl Gene ENSMUSG00000090268
Gene Namepredicted gene 5286
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL02603
Quality Score
Status
Chromosome3
Chromosomal Location94196714-94199802 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 94198437 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Serine at position 21 (T21S)
Ref Sequence ENSEMBL: ENSMUSP00000125267 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000159524]
Predicted Effect noncoding transcript
Transcript: ENSMUST00000159267
Predicted Effect possibly damaging
Transcript: ENSMUST00000159524
AA Change: T21S

PolyPhen 2 Score 0.532 (Sensitivity: 0.88; Specificity: 0.90)
SMART Domains Protein: ENSMUSP00000125267
Gene: ENSMUSG00000090268
AA Change: T21S

DomainStartEndE-ValueType
MATH 17 126 7.18e-6 SMART
BTB 184 283 8.21e-26 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 20 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrv1 A G 13: 81,488,952 S3457P possibly damaging Het
Aipl1 A G 11: 72,036,700 I63T possibly damaging Het
Atp7b C T 8: 21,994,776 V1307M possibly damaging Het
Cdc20b T C 13: 113,078,755 S286P possibly damaging Het
Eif2ak4 G A 2: 118,450,326 R946H probably damaging Het
Fam98c A G 7: 29,154,448 S232P probably damaging Het
Glt1d1 G T 5: 127,632,345 R21L probably damaging Het
Gm5422 A G 10: 31,249,440 noncoding transcript Het
Haao T A 17: 83,835,541 D125V probably benign Het
Hipk1 A G 3: 103,750,272 V832A probably damaging Het
Lrrtm4 C A 6: 80,022,984 Q460K possibly damaging Het
Lyar A G 5: 38,234,061 N368S probably damaging Het
Lyst G A 13: 13,660,956 C1741Y probably benign Het
Lztr1 C A 16: 17,509,686 N84K possibly damaging Het
Ndufa8 C A 2: 36,044,458 C36F probably damaging Het
Olfr136 T A 17: 38,335,513 S119T probably damaging Het
Olfr739 T A 14: 50,425,200 V227E probably damaging Het
Psg19 A G 7: 18,792,768 S146P probably benign Het
Rbm12 C T 2: 156,095,560 probably benign Het
Rnf123 G A 9: 108,068,302 R390* probably null Het
Other mutations in Gm5286
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01590:Gm5286 APN 3 94198367 utr 5 prime probably benign
Posted On2015-04-16