Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02607:Tex2'

300313

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tex2

Ensembl Gene

ENSMUSG00000040548

Gene Name

testis expressed gene 2

Synonyms

4930568E07Rik, Taz4, Def-5

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02607

Quality Score

Status

Chromosome

Chromosomal Location

106392973-106504249 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 106437573 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 699 (E699G)

Ref Sequence

ENSEMBL: ENSMUSP00000099359 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042780] [ENSMUST00000103070]

AlphaFold

Q6ZPJ0

Predicted Effect

unknown
Transcript: ENSMUST00000042780
AA Change: E699G

SMART Domains

Protein: ENSMUSP00000041985
Gene: ENSMUSG00000040548
AA Change: E699G

Domain	Start	End	E-Value	Type
low complexity region	119	186	N/A	INTRINSIC
low complexity region	319	341	N/A	INTRINSIC
low complexity region	346	360	N/A	INTRINSIC
transmembrane domain	473	492	N/A	INTRINSIC
transmembrane domain	494	516	N/A	INTRINSIC
PH	543	712	5.05e-1	SMART
low complexity region	732	752	N/A	INTRINSIC
low complexity region	811	823	N/A	INTRINSIC
low complexity region	946	965	N/A	INTRINSIC
low complexity region	1003	1016	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000103070
AA Change: E699G

SMART Domains

Protein: ENSMUSP00000099359
Gene: ENSMUSG00000040548
AA Change: E699G

Domain	Start	End	E-Value	Type
low complexity region	119	186	N/A	INTRINSIC
low complexity region	319	341	N/A	INTRINSIC
low complexity region	346	360	N/A	INTRINSIC
transmembrane domain	473	492	N/A	INTRINSIC
transmembrane domain	494	516	N/A	INTRINSIC
PH	543	712	5.05e-1	SMART
low complexity region	732	752	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000207249
AA Change: E201G

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 25 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca17	C	T	17: 24,546,679 (GRCm39)	W307*	probably null	Het
Cfap298	G	A	16: 90,726,835 (GRCm39)	T98M	probably damaging	Het
Cit	A	G	5: 115,997,268 (GRCm39)	I84V	probably benign	Het
Cltc	T	C	11: 86,597,540 (GRCm39)	D1132G	probably benign	Het
Cobll1	A	T	2: 64,981,429 (GRCm39)	S54T	probably damaging	Het
Dcstamp	A	G	15: 39,617,980 (GRCm39)	R130G	possibly damaging	Het
Dennd4a	A	G	9: 64,769,609 (GRCm39)	M439V	probably damaging	Het
Dnajc15	T	A	14: 78,077,656 (GRCm39)	I110F	probably damaging	Het
Dock1	T	C	7: 134,453,242 (GRCm39)	F824L	probably benign	Het
Eml2	A	G	7: 18,940,036 (GRCm39)	H617R	probably damaging	Het
Fgd6	A	T	10: 93,880,310 (GRCm39)	Q388L	possibly damaging	Het
Fkbp4	A	T	6: 128,411,433 (GRCm39)		probably benign	Het
Fmnl3	A	T	15: 99,222,653 (GRCm39)	L431Q	probably damaging	Het
Gng8	T	C	7: 16,628,859 (GRCm39)		probably benign	Het
Hmcn1	T	A	1: 150,620,746 (GRCm39)	I1155F	possibly damaging	Het
Muc4	G	T	16: 32,596,193 (GRCm39)	C3135F	possibly damaging	Het
Mycbp2	C	T	14: 103,522,709 (GRCm39)	G685D	probably damaging	Het
Or2y1d	T	C	11: 49,321,339 (GRCm39)	F12S	probably damaging	Het
Pcdhb8	A	T	18: 37,490,634 (GRCm39)	I771F	probably benign	Het
Pkn2	A	G	3: 142,499,862 (GRCm39)		probably null	Het
Rrn3	G	T	16: 13,624,427 (GRCm39)	V420L	possibly damaging	Het
Samm50	A	T	15: 84,092,039 (GRCm39)	Y338F	probably benign	Het
Slc2a7	C	T	4: 150,239,162 (GRCm39)	T129I	probably benign	Het
Tbc1d8	T	C	1: 39,418,592 (GRCm39)	I806V	probably benign	Het
Vmn2r85	T	C	10: 130,262,290 (GRCm39)	K150E	possibly damaging	Het

Other mutations in Tex2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Tex2	APN	11	106,459,361 (GRCm39)	missense	probably damaging	1.00
IGL01380:Tex2	APN	11	106,435,141 (GRCm39)	nonsense	probably null
IGL02680:Tex2	APN	11	106,459,058 (GRCm39)	unclassified	probably benign
IGL02699:Tex2	APN	11	106,459,259 (GRCm39)	missense	possibly damaging	0.53
IGL03187:Tex2	APN	11	106,458,903 (GRCm39)	unclassified	probably benign
IGL03398:Tex2	APN	11	106,459,098 (GRCm39)	missense	probably damaging	1.00
R0242:Tex2	UTSW	11	106,410,781 (GRCm39)	nonsense	probably null
R0242:Tex2	UTSW	11	106,410,781 (GRCm39)	nonsense	probably null
R1085:Tex2	UTSW	11	106,459,313 (GRCm39)	missense	probably damaging	0.98
R1491:Tex2	UTSW	11	106,394,466 (GRCm39)	missense	possibly damaging	0.72
R1664:Tex2	UTSW	11	106,458,608 (GRCm39)	unclassified	probably benign
R1794:Tex2	UTSW	11	106,458,728 (GRCm39)	unclassified	probably benign
R1855:Tex2	UTSW	11	106,437,702 (GRCm39)	missense	possibly damaging	0.87
R2077:Tex2	UTSW	11	106,397,690 (GRCm39)	splice site	probably null
R2151:Tex2	UTSW	11	106,458,161 (GRCm39)	unclassified	probably benign
R2175:Tex2	UTSW	11	106,394,513 (GRCm39)	missense	unknown
R2984:Tex2	UTSW	11	106,437,489 (GRCm39)	critical splice donor site	probably null
R3156:Tex2	UTSW	11	106,424,695 (GRCm39)	critical splice donor site	probably null
R3722:Tex2	UTSW	11	106,437,566 (GRCm39)	nonsense	probably null
R3724:Tex2	UTSW	11	106,420,156 (GRCm39)	missense	unknown
R3770:Tex2	UTSW	11	106,435,078 (GRCm39)	missense	unknown
R3771:Tex2	UTSW	11	106,437,720 (GRCm39)	missense	unknown
R3813:Tex2	UTSW	11	106,402,770 (GRCm39)	missense	unknown
R3947:Tex2	UTSW	11	106,410,829 (GRCm39)	missense	unknown
R4206:Tex2	UTSW	11	106,458,398 (GRCm39)	unclassified	probably benign
R4342:Tex2	UTSW	11	106,457,832 (GRCm39)	unclassified	probably benign
R4554:Tex2	UTSW	11	106,435,212 (GRCm39)	missense	unknown
R4896:Tex2	UTSW	11	106,459,230 (GRCm39)	missense	probably damaging	1.00
R5207:Tex2	UTSW	11	106,437,666 (GRCm39)	missense	unknown
R5249:Tex2	UTSW	11	106,437,615 (GRCm39)	missense	unknown
R5257:Tex2	UTSW	11	106,458,585 (GRCm39)	unclassified	probably benign
R5258:Tex2	UTSW	11	106,458,585 (GRCm39)	unclassified	probably benign
R5278:Tex2	UTSW	11	106,458,639 (GRCm39)	missense	probably benign	0.34
R5702:Tex2	UTSW	11	106,435,221 (GRCm39)	missense	possibly damaging	0.58
R5835:Tex2	UTSW	11	106,410,739 (GRCm39)	missense	unknown
R6150:Tex2	UTSW	11	106,457,906 (GRCm39)	missense	probably benign	0.34
R6785:Tex2	UTSW	11	106,424,776 (GRCm39)	missense	probably damaging	1.00
R6879:Tex2	UTSW	11	106,424,836 (GRCm39)	missense	unknown
R7038:Tex2	UTSW	11	106,402,726 (GRCm39)	critical splice donor site	probably null
R7117:Tex2	UTSW	11	106,435,071 (GRCm39)	missense	unknown
R7336:Tex2	UTSW	11	106,439,685 (GRCm39)	missense	unknown
R7568:Tex2	UTSW	11	106,439,562 (GRCm39)	missense	unknown
R7622:Tex2	UTSW	11	106,437,721 (GRCm39)	missense	unknown
R8228:Tex2	UTSW	11	106,457,997 (GRCm39)	missense	probably benign	0.34
R8407:Tex2	UTSW	11	106,459,221 (GRCm39)	missense	probably damaging	1.00
R8807:Tex2	UTSW	11	106,458,414 (GRCm39)	missense	unknown
R8807:Tex2	UTSW	11	106,435,194 (GRCm39)	missense	unknown
R8882:Tex2	UTSW	11	106,435,062 (GRCm39)	missense	unknown
R8926:Tex2	UTSW	11	106,459,230 (GRCm39)	missense
R8936:Tex2	UTSW	11	106,458,144 (GRCm39)	nonsense	probably null
R8988:Tex2	UTSW	11	106,402,731 (GRCm39)	missense	unknown
R9165:Tex2	UTSW	11	106,458,095 (GRCm39)	missense	unknown
R9294:Tex2	UTSW	11	106,459,361 (GRCm39)	missense	probably damaging	1.00
R9314:Tex2	UTSW	11	106,435,075 (GRCm39)	missense	unknown
R9405:Tex2	UTSW	11	106,435,214 (GRCm39)	missense	unknown
R9419:Tex2	UTSW	11	106,457,835 (GRCm39)	nonsense	probably null
R9477:Tex2	UTSW	11	106,410,706 (GRCm39)	critical splice donor site	probably null
R9626:Tex2	UTSW	11	106,437,579 (GRCm39)	missense	unknown
R9634:Tex2	UTSW	11	106,458,978 (GRCm39)	missense	unknown
T0970:Tex2	UTSW	11	106,437,772 (GRCm39)	missense	unknown
Z1177:Tex2	UTSW	11	106,424,834 (GRCm39)	missense	unknown

Posted On

2015-04-16