Mutagenetix > Incidental Mutation

Incidental Mutation 'R0363:Prrc2c'

30160

Institutional Source

Beutler Lab

Gene Symbol

Prrc2c

Ensembl Gene

ENSMUSG00000040225

Gene Name

proline-rich coiled-coil 2C

Synonyms

9630039I18Rik, Bat2d, 1810043M20Rik, Bat2l2

MMRRC Submission

038569-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.513) question?

Stock #

R0363 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

162499354-162568125 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 162525380 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 409 (S409P)

Ref Sequence

ENSEMBL: ENSMUSP00000138698 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000028016] [ENSMUST00000182149] [ENSMUST00000182393] [ENSMUST00000182593] [ENSMUST00000182660] [ENSMUST00000183223]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000028016
AA Change: S1833P

SMART Domains

Protein: ENSMUSP00000028016
Gene: ENSMUSG00000040225
AA Change: S1833P

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	164	7.7e-56	PFAM
internal_repeat_2	167	349	4.39e-5	PROSPERO
internal_repeat_1	336	391	2.14e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	2.14e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	4.39e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC
low complexity region	2811	2828	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000182149
AA Change: S1835P

SMART Domains

Protein: ENSMUSP00000138548
Gene: ENSMUSG00000040225
AA Change: S1835P

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	167	5.6e-73	PFAM
internal_repeat_1	336	391	1.49e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
internal_repeat_3	754	925	9.16e-5	PROSPERO
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	1.49e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	3.08e-5	PROSPERO
internal_repeat_3	1983	2153	9.16e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000182393
AA Change: S551P

SMART Domains

Protein: ENSMUSP00000138451
Gene: ENSMUSG00000040225
AA Change: S551P

Domain	Start	End	E-Value	Type
low complexity region	24	51	N/A	INTRINSIC
low complexity region	104	125	N/A	INTRINSIC
low complexity region	431	462	N/A	INTRINSIC
low complexity region	481	519	N/A	INTRINSIC
low complexity region	531	548	N/A	INTRINSIC
low complexity region	560	625	N/A	INTRINSIC
low complexity region	879	893	N/A	INTRINSIC
low complexity region	946	968	N/A	INTRINSIC
low complexity region	988	1002	N/A	INTRINSIC
low complexity region	1037	1054	N/A	INTRINSIC
low complexity region	1143	1154	N/A	INTRINSIC
low complexity region	1274	1297	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000182593
AA Change: S1833P

SMART Domains

Protein: ENSMUSP00000138674
Gene: ENSMUSG00000040225
AA Change: S1833P

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	165	4.1e-70	PFAM
internal_repeat_1	334	389	9.57e-6	PROSPERO
low complexity region	405	412	N/A	INTRINSIC
SCOP:d1eq1a_	445	589	3e-5	SMART
low complexity region	647	667	N/A	INTRINSIC
low complexity region	731	743	N/A	INTRINSIC
internal_repeat_3	752	923	6.11e-5	PROSPERO
coiled coil region	994	1024	N/A	INTRINSIC
low complexity region	1155	1184	N/A	INTRINSIC
low complexity region	1210	1220	N/A	INTRINSIC
internal_repeat_1	1238	1293	9.57e-6	PROSPERO
low complexity region	1306	1333	N/A	INTRINSIC
low complexity region	1386	1407	N/A	INTRINSIC
low complexity region	1713	1744	N/A	INTRINSIC
low complexity region	1763	1801	N/A	INTRINSIC
low complexity region	1813	1830	N/A	INTRINSIC
low complexity region	1842	1907	N/A	INTRINSIC
internal_repeat_2	1960	2146	2.01e-5	PROSPERO
internal_repeat_3	1981	2151	6.11e-5	PROSPERO
low complexity region	2161	2175	N/A	INTRINSIC
low complexity region	2228	2250	N/A	INTRINSIC
low complexity region	2270	2284	N/A	INTRINSIC
low complexity region	2319	2336	N/A	INTRINSIC
low complexity region	2425	2436	N/A	INTRINSIC
low complexity region	2551	2574	N/A	INTRINSIC
low complexity region	2671	2682	N/A	INTRINSIC
low complexity region	2730	2747	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000182660
AA Change: S1835P

SMART Domains

Protein: ENSMUSP00000138433
Gene: ENSMUSG00000040225
AA Change: S1835P

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	167	7e-73	PFAM
internal_repeat_1	336	391	2.14e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	2.14e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	4.39e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC
low complexity region	2811	2828	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000183223
AA Change: S409P

SMART Domains

Protein: ENSMUSP00000138698
Gene: ENSMUSG00000040225
AA Change: S409P

Domain	Start	End	E-Value	Type
low complexity region	289	320	N/A	INTRINSIC
low complexity region	339	377	N/A	INTRINSIC
low complexity region	389	406	N/A	INTRINSIC
low complexity region	418	483	N/A	INTRINSIC
low complexity region	739	761	N/A	INTRINSIC
low complexity region	781	795	N/A	INTRINSIC
low complexity region	830	847	N/A	INTRINSIC
low complexity region	936	947	N/A	INTRINSIC
low complexity region	1062	1085	N/A	INTRINSIC
low complexity region	1182	1193	N/A	INTRINSIC
low complexity region	1241	1258	N/A	INTRINSIC

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 98.9%
3x: 97.8%
10x: 94.7%
20x: 86.5%

Validation Efficiency

98% (78/80)

Allele List at MGI

Other mutations in this stock

Total: 75 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930522H14Rik	T	A	4: 109,381,520 (GRCm39)	Q86L	probably null	Het
Abhd2	A	G	7: 79,000,561 (GRCm39)	D262G	possibly damaging	Het
Abhd5	T	C	9: 122,197,211 (GRCm39)	F133L	possibly damaging	Het
Agap2	T	A	10: 126,926,834 (GRCm39)	V957E	probably damaging	Het
Ankrd12	T	C	17: 66,292,676 (GRCm39)	K919R	probably damaging	Het
Ap1m1	T	C	8: 73,006,738 (GRCm39)	S245P	probably benign	Het
Ap1m1	T	C	8: 73,010,568 (GRCm39)		probably benign	Het
Apcdd1	A	G	18: 63,070,168 (GRCm39)	Y145C	possibly damaging	Het
Apob	A	T	12: 8,060,136 (GRCm39)	N2840Y	probably damaging	Het
Arel1	A	G	12: 84,981,027 (GRCm39)	S327P	probably damaging	Het
Arhgap21	C	A	2: 20,885,944 (GRCm39)	R421L	probably damaging	Het
Ccdc85a	A	T	11: 28,533,400 (GRCm39)	I48N	probably damaging	Het
Chd6	A	G	2: 160,856,244 (GRCm39)	S672P	probably damaging	Het
Ciz1	G	C	2: 32,267,375 (GRCm39)		probably null	Het
Cmbl	G	A	15: 31,585,588 (GRCm39)		probably null	Het
Cmya5	A	G	13: 93,231,377 (GRCm39)	V1237A	possibly damaging	Het
Cntnap4	A	T	8: 113,583,143 (GRCm39)	K1074*	probably null	Het
Cntnap5b	A	G	1: 100,202,193 (GRCm39)	M347V	probably benign	Het
Col1a2	G	A	6: 4,518,822 (GRCm39)		probably benign	Het
Cuzd1	A	T	7: 130,917,991 (GRCm39)	M203K	probably benign	Het
Cyp3a16	T	C	5: 145,392,689 (GRCm39)		probably benign	Het
Dlgap3	A	G	4: 127,129,314 (GRCm39)	E892G	probably damaging	Het
Dnah7b	T	C	1: 46,275,948 (GRCm39)	S2612P	probably damaging	Het
Epas1	T	G	17: 87,113,276 (GRCm39)		probably benign	Het
Etv5	G	A	16: 22,230,458 (GRCm39)	A192V	probably benign	Het
Fa2h	T	A	8: 112,075,921 (GRCm39)	H234L	probably damaging	Het
Fcho1	T	C	8: 72,170,134 (GRCm39)	Y47C	probably damaging	Het
Flvcr1	T	A	1: 190,744,451 (GRCm39)		probably benign	Het
Il1rl1	CTTGTTGTTGTTGTTGTTG	CTTGTTGTTGTTGTTGTTGTTG	1: 40,481,734 (GRCm39)		probably benign	Het
Ino80	G	A	2: 119,213,441 (GRCm39)	R1249C	probably damaging	Het
Inpp4b	T	C	8: 82,610,886 (GRCm39)		probably benign	Het
Isy1	G	A	6: 87,796,167 (GRCm39)	R257W	probably damaging	Het
Kmt2a	A	G	9: 44,721,010 (GRCm39)		probably null	Het
Krt4	G	A	15: 101,833,081 (GRCm39)	R9C	possibly damaging	Het
Map1a	T	C	2: 121,132,525 (GRCm39)	S876P	probably damaging	Het
Mettl21e	A	G	1: 44,250,190 (GRCm39)		probably null	Het
Msh2	C	T	17: 88,024,904 (GRCm39)	T594M	probably benign	Het
Mtmr3	A	G	11: 4,437,536 (GRCm39)	S973P	probably damaging	Het
Muc5ac	A	T	7: 141,354,697 (GRCm39)	M889L	probably benign	Het
Ntn1	A	G	11: 68,276,369 (GRCm39)	I193T	probably benign	Het
Nudt13	A	T	14: 20,359,851 (GRCm39)	I193F	probably damaging	Het
Or2n1	A	G	17: 38,486,338 (GRCm39)	D121G	probably damaging	Het
Or3a1	C	T	11: 74,225,925 (GRCm39)	G44D	probably damaging	Het
Or4b1b	A	T	2: 90,112,200 (GRCm39)	S240T	probably damaging	Het
Or5p73	A	T	7: 108,064,941 (GRCm39)	T137S	possibly damaging	Het
Otulin	A	G	15: 27,606,381 (GRCm39)	V344A	probably damaging	Het
P2rx7	C	T	5: 122,795,093 (GRCm39)	Q128*	probably null	Het
Pcdhb22	G	A	18: 37,652,213 (GRCm39)	R227H	probably benign	Het
Plekha5	G	A	6: 140,537,473 (GRCm39)	R646K	possibly damaging	Het
Pltp	C	T	2: 164,682,056 (GRCm39)	R394H	probably benign	Het
Ppip5k1	C	G	2: 121,177,836 (GRCm39)	A324P	probably damaging	Het
Pramel14	C	T	4: 143,718,221 (GRCm39)	M407I	probably benign	Het
Prdm13	A	C	4: 21,679,737 (GRCm39)	V251G	unknown	Het
Prkg1	T	C	19: 31,641,596 (GRCm39)	E29G	probably damaging	Het
Rp1	T	A	1: 4,417,941 (GRCm39)	D1057V	probably damaging	Het
Rttn	G	A	18: 89,029,079 (GRCm39)	C599Y	probably damaging	Het
Shisa6	C	T	11: 66,416,153 (GRCm39)	R213Q	probably benign	Het
Slc3a1	T	C	17: 85,340,273 (GRCm39)	Y232H	probably damaging	Het
Slx4	G	A	16: 3,797,953 (GRCm39)	A1477V	probably damaging	Het
Ssrp1	T	G	2: 84,871,018 (GRCm39)	I218S	probably damaging	Het
St6galnac1	A	C	11: 116,659,756 (GRCm39)	S186A	probably benign	Het
Stab1	A	G	14: 30,880,965 (GRCm39)		probably benign	Het
Sycp2	T	C	2: 177,988,204 (GRCm39)		probably benign	Het
Syne2	T	A	12: 76,118,981 (GRCm39)	I5867N	probably damaging	Het
Taar7f	T	A	10: 23,925,839 (GRCm39)	D144E	probably damaging	Het
Tlcd5	A	T	9: 43,023,048 (GRCm39)	M84K	probably damaging	Het
Tmem87b	T	A	2: 128,673,153 (GRCm39)	S196T	probably damaging	Het
Tnfrsf21	A	G	17: 43,348,768 (GRCm39)	T127A	probably benign	Het
Trp73	A	G	4: 154,148,406 (GRCm39)	I336T	probably benign	Het
Ttl	A	G	2: 128,917,981 (GRCm39)	I148V	probably damaging	Het
Ttll7	T	C	3: 146,649,970 (GRCm39)	Y667H	probably benign	Het
Ubr4	A	G	4: 139,119,171 (GRCm39)	T152A	probably damaging	Het
Vmn1r58	A	T	7: 5,413,636 (GRCm39)	V198E	probably damaging	Het
Vps52	T	A	17: 34,181,091 (GRCm39)	F376L	probably benign	Het
Zfp1007	T	C	5: 109,824,754 (GRCm39)	E232G	probably benign	Het

Other mutations in Prrc2c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00425:Prrc2c	APN	1	162,548,182 (GRCm39)	splice site	probably null
IGL00577:Prrc2c	APN	1	162,525,685 (GRCm39)	missense	unknown
IGL00580:Prrc2c	APN	1	162,525,685 (GRCm39)	missense	unknown
IGL01295:Prrc2c	APN	1	162,510,061 (GRCm39)	missense	probably damaging	1.00
IGL01554:Prrc2c	APN	1	162,538,355 (GRCm39)	missense	probably damaging	0.99
IGL01684:Prrc2c	APN	1	162,534,031 (GRCm39)	unclassified	probably benign
IGL01745:Prrc2c	APN	1	162,552,297 (GRCm39)	missense	probably damaging	1.00
IGL01770:Prrc2c	APN	1	162,532,068 (GRCm39)	missense	probably benign	0.23
IGL01905:Prrc2c	APN	1	162,532,898 (GRCm39)	unclassified	probably benign
IGL02304:Prrc2c	APN	1	162,511,705 (GRCm39)	missense	probably benign	0.05
IGL02389:Prrc2c	APN	1	162,520,439 (GRCm39)	missense	probably damaging	1.00
IGL02540:Prrc2c	APN	1	162,550,706 (GRCm39)	missense	probably damaging	1.00
IGL02681:Prrc2c	APN	1	162,533,181 (GRCm39)	unclassified	probably benign
IGL02686:Prrc2c	APN	1	162,535,516 (GRCm39)	unclassified	probably benign
IGL02795:Prrc2c	APN	1	162,541,868 (GRCm39)	missense	probably benign
IGL02894:Prrc2c	APN	1	162,505,626 (GRCm39)	missense	probably damaging	1.00
IGL02957:Prrc2c	APN	1	162,534,104 (GRCm39)	unclassified	probably benign
IGL02981:Prrc2c	APN	1	162,532,748 (GRCm39)	unclassified	probably benign
IGL03070:Prrc2c	APN	1	162,504,978 (GRCm39)	missense	probably damaging	1.00
IGL03096:Prrc2c	APN	1	162,529,928 (GRCm39)	missense	unknown
R0058:Prrc2c	UTSW	1	162,526,453 (GRCm39)	missense	unknown
R0058:Prrc2c	UTSW	1	162,526,453 (GRCm39)	missense	unknown
R0135:Prrc2c	UTSW	1	162,543,052 (GRCm39)	splice site	probably benign
R0279:Prrc2c	UTSW	1	162,543,033 (GRCm39)	missense	probably damaging	1.00
R0436:Prrc2c	UTSW	1	162,532,883 (GRCm39)	unclassified	probably benign
R0605:Prrc2c	UTSW	1	162,509,995 (GRCm39)	missense	probably damaging	1.00
R0696:Prrc2c	UTSW	1	162,536,421 (GRCm39)	critical splice donor site	probably null
R0981:Prrc2c	UTSW	1	162,533,550 (GRCm39)	unclassified	probably benign
R1693:Prrc2c	UTSW	1	162,546,282 (GRCm39)	missense	probably damaging	0.98
R1714:Prrc2c	UTSW	1	162,504,945 (GRCm39)	missense	probably damaging	1.00
R1791:Prrc2c	UTSW	1	162,532,551 (GRCm39)	unclassified	probably benign
R1794:Prrc2c	UTSW	1	162,533,528 (GRCm39)	unclassified	probably benign
R1998:Prrc2c	UTSW	1	162,532,487 (GRCm39)	unclassified	probably benign
R2040:Prrc2c	UTSW	1	162,525,126 (GRCm39)	missense	probably damaging	1.00
R2168:Prrc2c	UTSW	1	162,537,903 (GRCm39)	unclassified	probably benign
R2246:Prrc2c	UTSW	1	162,535,360 (GRCm39)	unclassified	probably benign
R2830:Prrc2c	UTSW	1	162,536,485 (GRCm39)	unclassified	probably benign
R2926:Prrc2c	UTSW	1	162,533,696 (GRCm39)	unclassified	probably benign
R3703:Prrc2c	UTSW	1	162,538,260 (GRCm39)	missense	probably damaging	1.00
R3745:Prrc2c	UTSW	1	162,525,754 (GRCm39)	missense	unknown
R3760:Prrc2c	UTSW	1	162,520,420 (GRCm39)	missense	probably damaging	1.00
R3784:Prrc2c	UTSW	1	162,537,238 (GRCm39)	unclassified	probably benign
R3959:Prrc2c	UTSW	1	162,536,461 (GRCm39)	unclassified	probably benign
R4255:Prrc2c	UTSW	1	162,533,895 (GRCm39)	unclassified	probably benign
R4276:Prrc2c	UTSW	1	162,501,160 (GRCm39)	missense	probably damaging	1.00
R4421:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R4593:Prrc2c	UTSW	1	162,525,101 (GRCm39)	missense	probably damaging	1.00
R4651:Prrc2c	UTSW	1	162,550,843 (GRCm39)	missense	probably damaging	1.00
R4652:Prrc2c	UTSW	1	162,550,843 (GRCm39)	missense	probably damaging	1.00
R4660:Prrc2c	UTSW	1	162,508,464 (GRCm39)	missense	probably damaging	1.00
R4677:Prrc2c	UTSW	1	162,532,748 (GRCm39)	unclassified	probably benign
R4688:Prrc2c	UTSW	1	162,525,256 (GRCm39)	missense	unknown
R4753:Prrc2c	UTSW	1	162,518,799 (GRCm39)	missense	probably damaging	1.00
R4790:Prrc2c	UTSW	1	162,538,050 (GRCm39)	missense	unknown
R4981:Prrc2c	UTSW	1	162,520,116 (GRCm39)	missense	probably damaging	1.00
R4995:Prrc2c	UTSW	1	162,532,879 (GRCm39)	unclassified	probably benign
R5119:Prrc2c	UTSW	1	162,533,009 (GRCm39)	unclassified	probably benign
R5127:Prrc2c	UTSW	1	162,525,415 (GRCm39)	missense	unknown
R5291:Prrc2c	UTSW	1	162,533,151 (GRCm39)	unclassified	probably benign
R5474:Prrc2c	UTSW	1	162,537,213 (GRCm39)	unclassified	probably benign
R5543:Prrc2c	UTSW	1	162,501,080 (GRCm39)	missense	probably damaging	0.99
R5579:Prrc2c	UTSW	1	162,508,327 (GRCm39)	critical splice donor site	probably null
R5594:Prrc2c	UTSW	1	162,526,600 (GRCm39)	missense	unknown
R5620:Prrc2c	UTSW	1	162,501,098 (GRCm39)	missense	probably damaging	1.00
R5994:Prrc2c	UTSW	1	162,501,725 (GRCm39)	splice site	probably null
R6142:Prrc2c	UTSW	1	162,537,956 (GRCm39)	missense	unknown
R6199:Prrc2c	UTSW	1	162,510,085 (GRCm39)	missense	probably damaging	1.00
R6277:Prrc2c	UTSW	1	162,541,883 (GRCm39)	missense	probably benign
R6504:Prrc2c	UTSW	1	162,525,364 (GRCm39)	missense	unknown
R6671:Prrc2c	UTSW	1	162,525,154 (GRCm39)	missense	probably damaging	1.00
R6785:Prrc2c	UTSW	1	162,536,670 (GRCm39)	unclassified	probably benign
R6799:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6801:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6850:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6851:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6856:Prrc2c	UTSW	1	162,509,940 (GRCm39)	missense	probably damaging	1.00
R6869:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6882:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6884:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6897:Prrc2c	UTSW	1	162,533,075 (GRCm39)	unclassified	probably benign
R6934:Prrc2c	UTSW	1	162,548,074 (GRCm39)	missense	probably benign	0.10
R6976:Prrc2c	UTSW	1	162,520,413 (GRCm39)	missense	probably damaging	1.00
R7132:Prrc2c	UTSW	1	162,508,850 (GRCm39)	missense	possibly damaging	0.77
R7165:Prrc2c	UTSW	1	162,501,086 (GRCm39)	missense	possibly damaging	0.94
R7282:Prrc2c	UTSW	1	162,507,543 (GRCm39)	missense	possibly damaging	0.59
R7467:Prrc2c	UTSW	1	162,504,932 (GRCm39)	missense	possibly damaging	0.84
R7915:Prrc2c	UTSW	1	162,519,977 (GRCm39)	missense	probably benign	0.39
R8068:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R8529:Prrc2c	UTSW	1	162,536,663 (GRCm39)	unclassified	probably benign
R8734:Prrc2c	UTSW	1	162,507,081 (GRCm39)	missense	possibly damaging	0.92
R8735:Prrc2c	UTSW	1	162,537,127 (GRCm39)	missense	unknown
R8813:Prrc2c	UTSW	1	162,532,812 (GRCm39)	missense	unknown
R8946:Prrc2c	UTSW	1	162,536,478 (GRCm39)	unclassified	probably benign
R8975:Prrc2c	UTSW	1	162,533,630 (GRCm39)	missense	unknown
R9035:Prrc2c	UTSW	1	162,503,295 (GRCm39)	missense	possibly damaging	0.96
R9185:Prrc2c	UTSW	1	162,532,212 (GRCm39)	missense	unknown
R9261:Prrc2c	UTSW	1	162,505,622 (GRCm39)	missense	possibly damaging	0.48
R9287:Prrc2c	UTSW	1	162,541,843 (GRCm39)	missense	probably benign	0.34
R9289:Prrc2c	UTSW	1	162,507,130 (GRCm39)	missense	probably benign	0.33
R9466:Prrc2c	UTSW	1	162,503,258 (GRCm39)	missense	possibly damaging	0.53
R9523:Prrc2c	UTSW	1	162,525,298 (GRCm39)	missense	unknown
R9542:Prrc2c	UTSW	1	162,508,359 (GRCm39)	missense	possibly damaging	0.88
R9629:Prrc2c	UTSW	1	162,519,959 (GRCm39)	missense	possibly damaging	0.95
R9744:Prrc2c	UTSW	1	162,505,733 (GRCm39)	missense	possibly damaging	0.96
R9748:Prrc2c	UTSW	1	162,535,435 (GRCm39)	missense	unknown
X0020:Prrc2c	UTSW	1	162,535,416 (GRCm39)	unclassified	probably benign
X0039:Prrc2c	UTSW	1	162,532,362 (GRCm39)	frame shift	probably null

Predicted Primers

PCR Primer
(F):5'- CGGCTACGAAGTCTGTGCCATTAG -3'
(R):5'- TAGTTCCAGTGTCAACCCCAGCTC -3'

Sequencing Primer
(F):5'- CGTCTGAGCTGAGGGTAATCTAATC -3'
(R):5'- ccagttccaacctcagcc -3'

Posted On

2013-04-24