Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02680:Tex2'

303331

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tex2

Ensembl Gene

ENSMUSG00000040548

Gene Name

testis expressed gene 2

Synonyms

4930568E07Rik, Taz4, Def-5

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02680

Quality Score

Status

Chromosome

Chromosomal Location

106392973-106504249 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to A at 106459058 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042780] [ENSMUST00000103070] [ENSMUST00000128933] [ENSMUST00000153870]

AlphaFold

Q6ZPJ0

Predicted Effect

unknown
Transcript: ENSMUST00000042780
AA Change: Q124L

SMART Domains

Protein: ENSMUSP00000041985
Gene: ENSMUSG00000040548
AA Change: Q124L

Domain	Start	End	E-Value	Type
low complexity region	119	186	N/A	INTRINSIC
low complexity region	319	341	N/A	INTRINSIC
low complexity region	346	360	N/A	INTRINSIC
transmembrane domain	473	492	N/A	INTRINSIC
transmembrane domain	494	516	N/A	INTRINSIC
PH	543	712	5.05e-1	SMART
low complexity region	732	752	N/A	INTRINSIC
low complexity region	811	823	N/A	INTRINSIC
low complexity region	946	965	N/A	INTRINSIC
low complexity region	1003	1016	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000103070
AA Change: Q124L

SMART Domains

Protein: ENSMUSP00000099359
Gene: ENSMUSG00000040548
AA Change: Q124L

Domain	Start	End	E-Value	Type
low complexity region	119	186	N/A	INTRINSIC
low complexity region	319	341	N/A	INTRINSIC
low complexity region	346	360	N/A	INTRINSIC
transmembrane domain	473	492	N/A	INTRINSIC
transmembrane domain	494	516	N/A	INTRINSIC
PH	543	712	5.05e-1	SMART
low complexity region	732	752	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000128933
AA Change: Q124L

SMART Domains

Protein: ENSMUSP00000120781
Gene: ENSMUSG00000040548
AA Change: Q124L

Domain	Start	End	E-Value	Type
low complexity region	119	168	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000153870

Predicted Effect

probably benign
Transcript: ENSMUST00000207249

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921524L21Rik	T	A	18: 6,635,949 (GRCm39)		probably benign	Het
Aldh1a3	C	A	7: 66,055,895 (GRCm39)	V299F	probably damaging	Het
Ankar	A	G	1: 72,709,275 (GRCm39)	Y747H	probably damaging	Het
Armc9	T	C	1: 86,180,000 (GRCm39)	I107T	probably damaging	Het
Atmin	A	T	8: 117,684,236 (GRCm39)	D632V	probably damaging	Het
Atp5pd	C	A	11: 115,306,840 (GRCm39)		probably null	Het
Cadps2	T	C	6: 23,838,895 (GRCm39)	E81G	probably damaging	Het
Cep162	A	G	9: 87,128,797 (GRCm39)	V67A	possibly damaging	Het
Cfap100	C	T	6: 90,389,217 (GRCm39)	V335I	probably benign	Het
Dmtf1	A	T	5: 9,180,381 (GRCm39)	D181E	probably benign	Het
Efcab14	T	A	4: 115,597,615 (GRCm39)	I70N	probably damaging	Het
Frzb	T	C	2: 80,254,970 (GRCm39)	T189A	possibly damaging	Het
Fstl3	G	A	10: 79,614,506 (GRCm39)	W69*	probably null	Het
Gjb3	C	T	4: 127,219,815 (GRCm39)	C239Y	probably damaging	Het
Ifna1	A	G	4: 88,768,523 (GRCm39)	D67G	probably benign	Het
Inpp5d	A	G	1: 87,629,205 (GRCm39)	T397A	possibly damaging	Het
Myh11	G	T	16: 14,027,384 (GRCm39)	H1283Q	probably benign	Het
Naip6	A	G	13: 100,420,256 (GRCm39)	V1338A	probably benign	Het
Obscn	A	G	11: 58,890,846 (GRCm39)	S7229P	unknown	Het
Or1l4b	A	T	2: 37,036,427 (GRCm39)	I68F	probably damaging	Het
Pfkp	G	A	13: 6,650,708 (GRCm39)		probably benign	Het
Pop1	T	A	15: 34,502,619 (GRCm39)	I102K	probably damaging	Het
Ppp1r21	A	G	17: 88,891,290 (GRCm39)	M732V	probably benign	Het
Rsc1a1	A	G	4: 141,412,408 (GRCm39)	V168A	probably benign	Het
Scd2	G	A	19: 44,289,685 (GRCm39)	V227I	probably benign	Het
Scn10a	T	A	9: 119,495,125 (GRCm39)	Y372F	probably damaging	Het
Slc35c2	G	T	2: 165,124,055 (GRCm39)	T94K	probably damaging	Het
Slc41a2	A	G	10: 83,119,728 (GRCm39)	Y345H	probably benign	Het
Slc5a11	T	C	7: 122,864,854 (GRCm39)	S387P	probably damaging	Het
Smg7	T	A	1: 152,721,145 (GRCm39)	N727I	probably benign	Het
Steap2	A	T	5: 5,723,474 (GRCm39)	F469I	probably benign	Het
Tmem79	A	G	3: 88,240,270 (GRCm39)	L226P	probably damaging	Het
Tnfrsf14	G	T	4: 155,008,927 (GRCm39)	C165*	probably null	Het
Trim21	A	G	7: 102,208,870 (GRCm39)	V283A	probably benign	Het
Vmn2r16	A	T	5: 109,487,948 (GRCm39)	M274L	probably benign	Het

Other mutations in Tex2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Tex2	APN	11	106,459,361 (GRCm39)	missense	probably damaging	1.00
IGL01380:Tex2	APN	11	106,435,141 (GRCm39)	nonsense	probably null
IGL02607:Tex2	APN	11	106,437,573 (GRCm39)	missense	unknown
IGL02699:Tex2	APN	11	106,459,259 (GRCm39)	missense	possibly damaging	0.53
IGL03187:Tex2	APN	11	106,458,903 (GRCm39)	unclassified	probably benign
IGL03398:Tex2	APN	11	106,459,098 (GRCm39)	missense	probably damaging	1.00
R0242:Tex2	UTSW	11	106,410,781 (GRCm39)	nonsense	probably null
R0242:Tex2	UTSW	11	106,410,781 (GRCm39)	nonsense	probably null
R1085:Tex2	UTSW	11	106,459,313 (GRCm39)	missense	probably damaging	0.98
R1491:Tex2	UTSW	11	106,394,466 (GRCm39)	missense	possibly damaging	0.72
R1664:Tex2	UTSW	11	106,458,608 (GRCm39)	unclassified	probably benign
R1794:Tex2	UTSW	11	106,458,728 (GRCm39)	unclassified	probably benign
R1855:Tex2	UTSW	11	106,437,702 (GRCm39)	missense	possibly damaging	0.87
R2077:Tex2	UTSW	11	106,397,690 (GRCm39)	splice site	probably null
R2151:Tex2	UTSW	11	106,458,161 (GRCm39)	unclassified	probably benign
R2175:Tex2	UTSW	11	106,394,513 (GRCm39)	missense	unknown
R2984:Tex2	UTSW	11	106,437,489 (GRCm39)	critical splice donor site	probably null
R3156:Tex2	UTSW	11	106,424,695 (GRCm39)	critical splice donor site	probably null
R3722:Tex2	UTSW	11	106,437,566 (GRCm39)	nonsense	probably null
R3724:Tex2	UTSW	11	106,420,156 (GRCm39)	missense	unknown
R3770:Tex2	UTSW	11	106,435,078 (GRCm39)	missense	unknown
R3771:Tex2	UTSW	11	106,437,720 (GRCm39)	missense	unknown
R3813:Tex2	UTSW	11	106,402,770 (GRCm39)	missense	unknown
R3947:Tex2	UTSW	11	106,410,829 (GRCm39)	missense	unknown
R4206:Tex2	UTSW	11	106,458,398 (GRCm39)	unclassified	probably benign
R4342:Tex2	UTSW	11	106,457,832 (GRCm39)	unclassified	probably benign
R4554:Tex2	UTSW	11	106,435,212 (GRCm39)	missense	unknown
R4896:Tex2	UTSW	11	106,459,230 (GRCm39)	missense	probably damaging	1.00
R5207:Tex2	UTSW	11	106,437,666 (GRCm39)	missense	unknown
R5249:Tex2	UTSW	11	106,437,615 (GRCm39)	missense	unknown
R5257:Tex2	UTSW	11	106,458,585 (GRCm39)	unclassified	probably benign
R5258:Tex2	UTSW	11	106,458,585 (GRCm39)	unclassified	probably benign
R5278:Tex2	UTSW	11	106,458,639 (GRCm39)	missense	probably benign	0.34
R5702:Tex2	UTSW	11	106,435,221 (GRCm39)	missense	possibly damaging	0.58
R5835:Tex2	UTSW	11	106,410,739 (GRCm39)	missense	unknown
R6150:Tex2	UTSW	11	106,457,906 (GRCm39)	missense	probably benign	0.34
R6785:Tex2	UTSW	11	106,424,776 (GRCm39)	missense	probably damaging	1.00
R6879:Tex2	UTSW	11	106,424,836 (GRCm39)	missense	unknown
R7038:Tex2	UTSW	11	106,402,726 (GRCm39)	critical splice donor site	probably null
R7117:Tex2	UTSW	11	106,435,071 (GRCm39)	missense	unknown
R7336:Tex2	UTSW	11	106,439,685 (GRCm39)	missense	unknown
R7568:Tex2	UTSW	11	106,439,562 (GRCm39)	missense	unknown
R7622:Tex2	UTSW	11	106,437,721 (GRCm39)	missense	unknown
R8228:Tex2	UTSW	11	106,457,997 (GRCm39)	missense	probably benign	0.34
R8407:Tex2	UTSW	11	106,459,221 (GRCm39)	missense	probably damaging	1.00
R8807:Tex2	UTSW	11	106,458,414 (GRCm39)	missense	unknown
R8807:Tex2	UTSW	11	106,435,194 (GRCm39)	missense	unknown
R8882:Tex2	UTSW	11	106,435,062 (GRCm39)	missense	unknown
R8926:Tex2	UTSW	11	106,459,230 (GRCm39)	missense
R8936:Tex2	UTSW	11	106,458,144 (GRCm39)	nonsense	probably null
R8988:Tex2	UTSW	11	106,402,731 (GRCm39)	missense	unknown
R9165:Tex2	UTSW	11	106,458,095 (GRCm39)	missense	unknown
R9294:Tex2	UTSW	11	106,459,361 (GRCm39)	missense	probably damaging	1.00
R9314:Tex2	UTSW	11	106,435,075 (GRCm39)	missense	unknown
R9405:Tex2	UTSW	11	106,435,214 (GRCm39)	missense	unknown
R9419:Tex2	UTSW	11	106,457,835 (GRCm39)	nonsense	probably null
R9477:Tex2	UTSW	11	106,410,706 (GRCm39)	critical splice donor site	probably null
R9626:Tex2	UTSW	11	106,437,579 (GRCm39)	missense	unknown
R9634:Tex2	UTSW	11	106,458,978 (GRCm39)	missense	unknown
T0970:Tex2	UTSW	11	106,437,772 (GRCm39)	missense	unknown
Z1177:Tex2	UTSW	11	106,424,834 (GRCm39)	missense	unknown

Posted On

2015-04-16