Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02695:Cd300c2'

303911

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cd300c2

Ensembl Gene

ENSMUSG00000044811

Gene Name

CD300C molecule 2

Synonyms

MAIR-II, Cd300d, Igsf7, LMIR2, DIgR1, AF251705, Clm4

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02695

Quality Score

Status

Chromosome

Chromosomal Location

114887595-114892706 bp(-) (GRCm39)

Type of Mutation

utr 5 prime

DNA Base Change (assembly)

C to T at 114892379 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000124035 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092464] [ENSMUST00000141188]

AlphaFold

Q7TSN2

Predicted Effect

probably benign
Transcript: ENSMUST00000092464

SMART Domains

Protein: ENSMUSP00000090121
Gene: ENSMUSG00000044811

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
IG	28	134	1.52e-3	SMART
transmembrane domain	187	209	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000141188

SMART Domains

Protein: ENSMUSP00000124035
Gene: ENSMUSG00000044811

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased stimulated B cell proliferation. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam2	A	T	14: 66,287,929 (GRCm39)	M389K	probably benign	Het
Adamts4	C	A	1: 171,080,203 (GRCm39)	T252K	probably damaging	Het
Adgrb2	G	A	4: 129,912,625 (GRCm39)	G1293D	probably damaging	Het
Ankfn1	T	C	11: 89,282,645 (GRCm39)	E1013G	probably damaging	Het
Ankrd34b	C	A	13: 92,576,120 (GRCm39)	H451N	possibly damaging	Het
Cntnap3	T	G	13: 64,919,946 (GRCm39)	Q637P	probably benign	Het
Cpne6	A	T	14: 55,752,037 (GRCm39)	I265F	probably damaging	Het
Dot1l	C	A	10: 80,613,442 (GRCm39)	T18K	probably damaging	Het
Fam83c	T	C	2: 155,673,435 (GRCm39)	D251G	probably benign	Het
Fyb1	A	G	15: 6,610,402 (GRCm39)	K325R	probably damaging	Het
Gas2l2	T	A	11: 83,313,468 (GRCm39)	I615F	probably damaging	Het
Gigyf2	A	G	1: 87,344,549 (GRCm39)	N494S	probably benign	Het
Gnaz	T	C	10: 74,827,974 (GRCm39)		probably null	Het
Haus5	A	T	7: 30,362,702 (GRCm39)	L36Q	probably damaging	Het
Hecw2	C	T	1: 53,965,368 (GRCm39)	G486D	possibly damaging	Het
Hmcn2	T	C	2: 31,298,985 (GRCm39)	F2777S	possibly damaging	Het
Il1rl1	T	C	1: 40,485,718 (GRCm39)	S290P	possibly damaging	Het
Itgam	G	T	7: 127,685,113 (GRCm39)	A409S	possibly damaging	Het
Kdm5b	T	A	1: 134,532,223 (GRCm39)	M467K	possibly damaging	Het
Lama2	A	C	10: 26,876,771 (GRCm39)	V2725G	probably benign	Het
Lhpp	G	A	7: 132,252,063 (GRCm39)	R234Q	probably damaging	Het
Maf1	T	C	15: 76,236,955 (GRCm39)	S65P	possibly damaging	Het
Mgat5	T	A	1: 127,339,868 (GRCm39)	H416Q	probably damaging	Het
Mta2	A	G	19: 8,925,728 (GRCm39)	T408A	probably benign	Het
Neb	T	A	2: 52,145,603 (GRCm39)	I2974F	probably damaging	Het
Neb	C	T	2: 52,101,608 (GRCm39)		probably benign	Het
Or1j19	C	T	2: 36,677,332 (GRCm39)	S265L	possibly damaging	Het
Or2d4	A	G	7: 106,543,870 (GRCm39)	S113P	possibly damaging	Het
Or52p1	A	G	7: 104,267,678 (GRCm39)	H264R	probably damaging	Het
Or5w22	C	T	2: 87,362,461 (GRCm39)	T28I	probably benign	Het
Pcca	T	A	14: 122,820,150 (GRCm39)		probably benign	Het
Prlr	T	C	15: 10,328,451 (GRCm39)	F309L	probably benign	Het
Slc28a1	A	T	7: 80,817,739 (GRCm39)	Y536F	probably benign	Het
Slco1a8	A	G	6: 141,933,486 (GRCm39)	V433A	probably damaging	Het
Stab1	T	A	14: 30,881,228 (GRCm39)	N601Y	probably damaging	Het
Stil	G	T	4: 114,873,372 (GRCm39)	V332F	probably damaging	Het
Stk11	A	G	10: 79,961,311 (GRCm39)		probably null	Het
Tmem59	A	G	4: 107,050,511 (GRCm39)	N147S	probably benign	Het

Other mutations in Cd300c2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00092:Cd300c2	APN	11	114,892,375 (GRCm39)	utr 5 prime	probably benign
IGL03086:Cd300c2	APN	11	114,891,649 (GRCm39)	missense	possibly damaging	0.76
R1933:Cd300c2	UTSW	11	114,891,685 (GRCm39)	missense	probably benign	0.22
R4707:Cd300c2	UTSW	11	114,887,811 (GRCm39)	missense	probably benign	0.03
R4866:Cd300c2	UTSW	11	114,891,807 (GRCm39)	nonsense	probably null
R4900:Cd300c2	UTSW	11	114,891,807 (GRCm39)	nonsense	probably null
R4906:Cd300c2	UTSW	11	114,887,826 (GRCm39)	missense	possibly damaging	0.85
R4908:Cd300c2	UTSW	11	114,887,772 (GRCm39)	missense	probably damaging	0.97
R4946:Cd300c2	UTSW	11	114,887,731 (GRCm39)	missense	probably benign	0.04
R5568:Cd300c2	UTSW	11	114,891,662 (GRCm39)	missense	probably damaging	1.00
R6870:Cd300c2	UTSW	11	114,891,503 (GRCm39)	missense	probably damaging	0.99
R7474:Cd300c2	UTSW	11	114,889,122 (GRCm39)	missense	probably benign	0.00
R7826:Cd300c2	UTSW	11	114,891,644 (GRCm39)	missense	possibly damaging	0.77
R8210:Cd300c2	UTSW	11	114,891,634 (GRCm39)	missense	possibly damaging	0.89
R8443:Cd300c2	UTSW	11	114,891,466 (GRCm39)	missense	probably benign	0.42
R8831:Cd300c2	UTSW	11	114,891,844 (GRCm39)	nonsense	probably null
R9405:Cd300c2	UTSW	11	114,891,587 (GRCm39)	missense	probably damaging	1.00
R9762:Cd300c2	UTSW	11	114,887,775 (GRCm39)	missense	probably damaging	1.00

Posted On

2015-04-16