Incidental Mutation 'IGL02701:1700015F17Rik'
ID304149
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 1700015F17Rik
Ensembl Gene ENSMUSG00000079666
Gene NameRIKEN cDNA 1700015F17 gene
SynonymsLOC381716
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.216) question?
Stock #IGL02701
Quality Score
Status
Chromosome5
Chromosomal Location5437827-5479143 bp(-) (GRCm38)
Type of Mutationcritical splice donor site (2 bp from exon)
DNA Base Change (assembly) A to G at 5466623 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000111107 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000115447] [ENSMUST00000156282]
Predicted Effect probably null
Transcript: ENSMUST00000115447
SMART Domains Protein: ENSMUSP00000111107
Gene: ENSMUSG00000079666

DomainStartEndE-ValueType
signal peptide 1 19 N/A INTRINSIC
low complexity region 30 41 N/A INTRINSIC
transmembrane domain 99 121 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000156282
SMART Domains Protein: ENSMUSP00000122651
Gene: ENSMUSG00000079666

DomainStartEndE-ValueType
transmembrane domain 5 27 N/A INTRINSIC
low complexity region 30 41 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4833423E24Rik A G 2: 85,484,169 L480P probably damaging Het
Arhgap21 A G 2: 20,892,091 C125R probably damaging Het
Blmh A G 11: 76,971,910 D383G probably benign Het
Brca1 T C 11: 101,525,235 E691G probably damaging Het
Chrm3 G A 13: 9,878,464 R179* probably null Het
Cnrip1 A G 11: 17,078,415 T116A probably benign Het
Csmd2 T C 4: 128,496,141 V2223A probably benign Het
Dalrd3 T A 9: 108,572,284 V143D possibly damaging Het
Ddx60 A T 8: 61,979,341 I886L probably damaging Het
Dennd4a T C 9: 64,897,353 F1325L possibly damaging Het
Dnmt3l A T 10: 78,055,022 T253S probably benign Het
Gde1 T A 7: 118,698,637 T9S probably damaging Het
Ggcx T A 6: 72,418,472 probably benign Het
Gm813 G A 16: 58,615,807 S51L probably benign Het
Hspg2 C T 4: 137,557,174 A3481V probably damaging Het
Igf1r T C 7: 68,201,249 Y931H possibly damaging Het
Ighv12-3 A C 12: 114,366,801 S25A probably damaging Het
Itga5 A C 15: 103,347,766 C920G probably damaging Het
Kmt5b A G 19: 3,796,681 D118G probably benign Het
Lrp1b T G 2: 41,246,017 N1647T possibly damaging Het
Lrrc71 T C 3: 87,741,772 E363G probably benign Het
Mapk1 A G 16: 17,015,906 Y41C probably benign Het
Mib1 T C 18: 10,747,357 V178A probably damaging Het
Olfr1022 A G 2: 85,869,458 I289V probably benign Het
Olfr159 A G 4: 43,770,366 I215T probably benign Het
Olfr472 A T 7: 107,903,442 T242S probably benign Het
Plb1 T C 5: 32,364,197 V1464A unknown Het
Plekhg5 T C 4: 152,103,022 S82P probably damaging Het
Plxna4 T C 6: 32,517,559 T41A probably benign Het
Ppip5k1 A C 2: 121,316,649 probably null Het
Rpl14 T C 9: 120,573,573 probably benign Het
Slc44a2 T C 9: 21,347,951 F554L probably benign Het
Slco1b2 T A 6: 141,685,545 V635E probably benign Het
Sv2a T A 3: 96,187,131 C261S probably damaging Het
Thbs2 T C 17: 14,683,361 I353V probably benign Het
Tspan4 G A 7: 141,492,028 V205M probably damaging Het
Vezf1 A T 11: 88,076,221 R93* probably null Het
Wwox T A 8: 114,706,368 V258D probably damaging Het
Zmynd12 G T 4: 119,444,755 probably benign Het
Other mutations in 1700015F17Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02125:1700015F17Rik APN 5 5450644 makesense probably null
IGL02821:1700015F17Rik APN 5 5452039 nonsense probably null
R1029:1700015F17Rik UTSW 5 5455919 missense probably benign 0.21
R1463:1700015F17Rik UTSW 5 5452073 splice site probably benign
R1525:1700015F17Rik UTSW 5 5452019 missense probably benign 0.00
R1550:1700015F17Rik UTSW 5 5452019 missense probably benign 0.00
R1764:1700015F17Rik UTSW 5 5478943 missense possibly damaging 0.83
R1911:1700015F17Rik UTSW 5 5452019 missense probably benign 0.00
R1912:1700015F17Rik UTSW 5 5452019 missense probably benign 0.00
R1930:1700015F17Rik UTSW 5 5452019 missense probably benign 0.00
R1931:1700015F17Rik UTSW 5 5452019 missense probably benign 0.00
R2013:1700015F17Rik UTSW 5 5455964 missense probably benign 0.00
R2014:1700015F17Rik UTSW 5 5455964 missense probably benign 0.00
R2015:1700015F17Rik UTSW 5 5455964 missense probably benign 0.00
R2151:1700015F17Rik UTSW 5 5478875 missense possibly damaging 0.46
R2420:1700015F17Rik UTSW 5 5455912 missense probably benign 0.00
R2421:1700015F17Rik UTSW 5 5455912 missense probably benign 0.00
R3056:1700015F17Rik UTSW 5 5457283 critical splice donor site probably null
R4012:1700015F17Rik UTSW 5 5478955 missense probably damaging 1.00
Posted On2015-04-16