Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02708:Vmn1r91'

304439

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r91

Ensembl Gene

ENSMUSG00000095201

Gene Name

vomeronasal 1 receptor 91

Synonyms

Gm8442

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.171) question?

Stock #

IGL02708

Quality Score

Status

Chromosome

Chromosomal Location

19835083-19836006 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 19835415 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Arginine at position 111 (S111R)

Ref Sequence

ENSEMBL: ENSMUSP00000129283 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000165330]

AlphaFold

E9PZR7

Predicted Effect

probably damaging
Transcript: ENSMUST00000165330
AA Change: S111R

PolyPhen 2 Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000129283
Gene: ENSMUSG00000095201
AA Change: S111R

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	299	5.1e-18	PFAM
Pfam:V1R	41	298	7.1e-15	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc4	A	T	14: 118,738,213 (GRCm39)	V1104D	probably damaging	Het
Adgrl2	A	T	3: 148,532,161 (GRCm39)	V1024E	probably damaging	Het
Agbl2	A	G	2: 90,631,686 (GRCm39)	H348R	probably benign	Het
Aifm2	T	C	10: 61,574,354 (GRCm39)		probably benign	Het
Ankrd26	T	C	6: 118,495,379 (GRCm39)		probably benign	Het
Avpr1b	A	G	1: 131,528,389 (GRCm39)	D304G	probably damaging	Het
Duox1	A	G	2: 122,156,498 (GRCm39)	D475G	possibly damaging	Het
E2f8	T	C	7: 48,516,982 (GRCm39)		probably null	Het
Fat2	T	A	11: 55,173,211 (GRCm39)	I2501F	probably damaging	Het
Gm4181	A	G	14: 51,870,689 (GRCm39)	C91R	probably benign	Het
Gm5424	T	A	10: 61,907,390 (GRCm39)		noncoding transcript	Het
Gnai3	A	G	3: 108,025,660 (GRCm39)	F140L	probably benign	Het
Htra1	A	T	7: 130,563,765 (GRCm39)	D212V	probably damaging	Het
Irgm2	T	C	11: 58,111,350 (GRCm39)	V347A	probably benign	Het
Itch	A	G	2: 155,015,964 (GRCm39)	T150A	probably benign	Het
Itgb3	A	C	11: 104,528,655 (GRCm39)	I261L	possibly damaging	Het
Kalrn	C	T	16: 34,212,420 (GRCm39)	V31M	probably damaging	Het
Klra7	C	T	6: 130,203,463 (GRCm39)	C181Y	probably damaging	Het
Klrb1	A	G	6: 128,690,548 (GRCm39)	L58S	probably benign	Het
Kndc1	A	G	7: 139,481,097 (GRCm39)	E61G	probably damaging	Het
Krt78	T	A	15: 101,861,842 (GRCm39)	T135S	possibly damaging	Het
Mpdz	A	G	4: 81,202,808 (GRCm39)		probably null	Het
Mphosph6	A	G	8: 118,519,525 (GRCm39)		probably benign	Het
Myo19	T	C	11: 84,790,222 (GRCm39)	S393P	possibly damaging	Het
Or51a5	A	G	7: 102,771,027 (GRCm39)		probably benign	Het
Or8g53	T	C	9: 39,683,214 (GRCm39)	N294S	probably damaging	Het
Pkdrej	T	C	15: 85,704,988 (GRCm39)	Y316C	probably damaging	Het
Pkp3	A	T	7: 140,669,681 (GRCm39)		probably benign	Het
Pramel31	T	A	4: 144,089,983 (GRCm39)	L341H	probably damaging	Het
Psmb8	A	G	17: 34,420,217 (GRCm39)	K270E	probably benign	Het
Ptprq	T	C	10: 107,488,561 (GRCm39)	N959D	probably damaging	Het
Rab6b	T	G	9: 103,038,074 (GRCm39)		probably null	Het
Rhobtb3	T	C	13: 76,065,843 (GRCm39)	D180G	probably damaging	Het
Sccpdh	G	A	1: 179,508,074 (GRCm39)	C238Y	probably benign	Het
Srm	C	T	4: 148,677,803 (GRCm39)	S147L	probably benign	Het
Synj1	A	T	16: 90,788,350 (GRCm39)	S173T	probably damaging	Het
Tas1r1	T	C	4: 152,112,797 (GRCm39)	E752G	possibly damaging	Het
Tmem151a	G	T	19: 5,132,875 (GRCm39)	Y110*	probably null	Het
Ttn	A	G	2: 76,556,957 (GRCm39)	V30016A	probably damaging	Het
Txnrd2	A	G	16: 18,287,590 (GRCm39)	E331G	probably benign	Het
Vldlr	T	C	19: 27,215,485 (GRCm39)	C161R	possibly damaging	Het
Vmn2r66	T	A	7: 84,655,796 (GRCm39)	I407F	probably benign	Het
Vps13d	T	C	4: 144,854,850 (GRCm39)	M2258V	probably benign	Het
Ypel1	A	T	16: 16,923,872 (GRCm39)	V59D	probably benign	Het

Other mutations in Vmn1r91

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01875:Vmn1r91	APN	7	19,835,859 (GRCm39)	nonsense	probably null
IGL02125:Vmn1r91	APN	7	19,835,429 (GRCm39)	missense	probably damaging	0.96
IGL02263:Vmn1r91	APN	7	19,835,768 (GRCm39)	missense	probably benign	0.00
IGL02338:Vmn1r91	APN	7	19,835,671 (GRCm39)	missense	probably damaging	0.96
R1880:Vmn1r91	UTSW	7	19,835,698 (GRCm39)	missense	probably damaging	1.00
R2679:Vmn1r91	UTSW	7	19,835,983 (GRCm39)	missense	probably damaging	0.97
R4730:Vmn1r91	UTSW	7	19,835,695 (GRCm39)	missense	possibly damaging	0.71
R5362:Vmn1r91	UTSW	7	19,835,386 (GRCm39)	missense	probably benign	0.05
R5633:Vmn1r91	UTSW	7	19,835,870 (GRCm39)	missense	possibly damaging	0.56
R5979:Vmn1r91	UTSW	7	19,835,990 (GRCm39)	missense	probably benign	0.00
R6151:Vmn1r91	UTSW	7	19,835,360 (GRCm39)	missense	probably benign
R6177:Vmn1r91	UTSW	7	19,835,404 (GRCm39)	missense	possibly damaging	0.95
R7397:Vmn1r91	UTSW	7	19,835,695 (GRCm39)	missense	possibly damaging	0.71
R7589:Vmn1r91	UTSW	7	19,835,802 (GRCm39)	missense	probably benign	0.07
R7872:Vmn1r91	UTSW	7	19,835,839 (GRCm39)	missense	probably benign	0.26
R7886:Vmn1r91	UTSW	7	19,835,490 (GRCm39)	missense	probably benign
R7903:Vmn1r91	UTSW	7	19,835,135 (GRCm39)	missense	possibly damaging	0.88
R7953:Vmn1r91	UTSW	7	19,835,218 (GRCm39)	missense	possibly damaging	0.68
R8043:Vmn1r91	UTSW	7	19,835,218 (GRCm39)	missense	possibly damaging	0.68
R8202:Vmn1r91	UTSW	7	19,835,749 (GRCm39)	missense	probably damaging	1.00

Posted On

2015-04-16