Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02712:Spata32'

304629

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Spata32

Ensembl Gene

ENSMUSG00000044787

Gene Name

spermatogenesis associated 32

Synonyms

4933400C05Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.048) question?

Stock #

IGL02712

Quality Score

Status

Chromosome

Chromosomal Location

103098953-103109258 bp(-) (GRCm39)

Type of Mutation

intron

DNA Base Change (assembly)

T to G at 103098973 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000134292 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000021323] [ENSMUST00000103076] [ENSMUST00000107026] [ENSMUST00000172850] [ENSMUST00000174567]

AlphaFold

Q8C5V0

Predicted Effect

probably benign
Transcript: ENSMUST00000021323

SMART Domains

Protein: ENSMUSP00000021323
Gene: ENSMUSG00000020940

Domain	Start	End	E-Value	Type
EFh	109	137	7.23e1	SMART
EFh	145	173	6.68e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000103076

SMART Domains

Protein: ENSMUSP00000099365
Gene: ENSMUSG00000044787

Domain	Start	End	E-Value	Type
low complexity region	25	48	N/A	INTRINSIC
Pfam:VAD1-2	106	332	3e-87	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000107026

SMART Domains

Protein: ENSMUSP00000102641
Gene: ENSMUSG00000020940

Domain	Start	End	E-Value	Type
EFh	40	68	7.23e1	SMART
EFh	76	104	6.68e-1	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000140559

Predicted Effect

probably benign
Transcript: ENSMUST00000172850

SMART Domains

Protein: ENSMUSP00000139837
Gene: ENSMUSG00000020940

Domain	Start	End	E-Value	Type
EFh	109	137	3.5e-1	SMART
EFh	145	173	3.2e-3	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000174567

SMART Domains

Protein: ENSMUSP00000134292
Gene: ENSMUSG00000020940

Domain	Start	End	E-Value	Type
SCOP:d1mr8a_	153	209	5e-8	SMART
Blast:EFh	159	187	4e-12	BLAST

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Angel1	A	G	12: 86,769,613 (GRCm39)		probably benign	Het
Arhgef33	T	A	17: 80,667,802 (GRCm39)	V289D	probably damaging	Het
Cabp5	A	G	7: 13,137,271 (GRCm39)	M93V	probably damaging	Het
Ces1a	A	C	8: 93,762,668 (GRCm39)	V201G	probably damaging	Het
Cisd1	A	G	10: 71,172,181 (GRCm39)	F34L	probably benign	Het
Cyp26a1	T	C	19: 37,688,426 (GRCm39)	L316P	probably damaging	Het
Ddx39a	A	G	8: 84,448,386 (GRCm39)	I213V	probably benign	Het
Ddx59	A	T	1: 136,367,519 (GRCm39)	N542I	probably benign	Het
Dytn	T	C	1: 63,703,581 (GRCm39)	T233A	probably benign	Het
Fbxo7	A	G	10: 85,860,302 (GRCm39)	T49A	possibly damaging	Het
Fmnl2	C	A	2: 52,926,510 (GRCm39)		probably benign	Het
Golga2	G	T	2: 32,194,225 (GRCm39)	K610N	probably damaging	Het
Hipk4	T	C	7: 27,228,060 (GRCm39)	Y269H	probably damaging	Het
Ifi209	T	C	1: 173,470,267 (GRCm39)	V285A	possibly damaging	Het
Ifna1	A	G	4: 88,768,523 (GRCm39)	D67G	probably benign	Het
Map3k13	T	G	16: 21,724,005 (GRCm39)	V329G	probably damaging	Het
Mrm3	T	C	11: 76,134,683 (GRCm39)	W29R	possibly damaging	Het
Nherf1	T	C	11: 115,068,060 (GRCm39)	V200A	possibly damaging	Het
Nos1ap	T	C	1: 170,156,820 (GRCm39)	I213V	possibly damaging	Het
Nphp4	C	T	4: 152,640,732 (GRCm39)	T1033M	probably damaging	Het
Nr5a2	T	C	1: 136,868,266 (GRCm39)		probably null	Het
Nrcam	A	G	12: 44,620,610 (GRCm39)	Y885C	probably damaging	Het
Odr4	A	G	1: 150,262,107 (GRCm39)		probably null	Het
Or1e17	T	C	11: 73,831,756 (GRCm39)	V228A	probably benign	Het
Or8b57	T	C	9: 40,004,082 (GRCm39)	H60R	probably damaging	Het
Ovgp1	T	A	3: 105,893,829 (GRCm39)		probably benign	Het
Pdzd2	T	C	15: 12,376,113 (GRCm39)	S1341G	probably benign	Het
Pld2	T	G	11: 70,447,905 (GRCm39)	L856R	probably benign	Het
Plod1	A	G	4: 148,003,344 (GRCm39)	F494L	possibly damaging	Het
Pnkd	T	A	1: 74,389,027 (GRCm39)	S233T	possibly damaging	Het
Rnf144b	T	C	13: 47,393,255 (GRCm39)	I198T	probably damaging	Het
Rsc1a1	G	T	4: 141,412,376 (GRCm39)	Q179K	probably benign	Het
Slc5a10	C	T	11: 61,598,632 (GRCm39)	W249*	probably null	Het
Stk4	T	A	2: 163,938,817 (GRCm39)	H228Q	probably damaging	Het
Szt2	T	A	4: 118,242,030 (GRCm39)	Q1592L	probably benign	Het
Tnc	T	A	4: 63,893,493 (GRCm39)	I1598F	probably damaging	Het
Togaram2	A	T	17: 72,011,749 (GRCm39)	D476V	probably benign	Het
Ttll6	T	G	11: 96,030,601 (GRCm39)		probably benign	Het
Vmn2r118	A	G	17: 55,899,655 (GRCm39)	S750P	probably benign	Het
Zswim5	C	T	4: 116,842,892 (GRCm39)	T879I	probably damaging	Het

Other mutations in Spata32

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02422:Spata32	APN	11	103,099,706 (GRCm39)	missense	probably benign	0.38
IGL02966:Spata32	APN	11	103,099,629 (GRCm39)	missense	possibly damaging	0.89
IGL03178:Spata32	APN	11	103,101,588 (GRCm39)	missense	probably benign
PIT4469001:Spata32	UTSW	11	103,100,653 (GRCm39)	missense	probably benign	0.14
R0245:Spata32	UTSW	11	103,099,921 (GRCm39)	missense	probably damaging	0.99
R0454:Spata32	UTSW	11	103,100,125 (GRCm39)	missense	probably damaging	1.00
R1773:Spata32	UTSW	11	103,099,644 (GRCm39)	missense	probably damaging	1.00
R1881:Spata32	UTSW	11	103,101,561 (GRCm39)	unclassified	probably benign
R3545:Spata32	UTSW	11	103,101,570 (GRCm39)	missense	possibly damaging	0.67
R5485:Spata32	UTSW	11	103,100,122 (GRCm39)	missense	probably damaging	0.96
R5576:Spata32	UTSW	11	103,100,653 (GRCm39)	missense	possibly damaging	0.87
R8966:Spata32	UTSW	11	103,100,143 (GRCm39)	missense	probably damaging	0.98
R9011:Spata32	UTSW	11	103,100,677 (GRCm39)	missense	probably benign	0.04
R9448:Spata32	UTSW	11	103,099,648 (GRCm39)	missense	probably damaging	1.00
R9469:Spata32	UTSW	11	103,099,741 (GRCm39)	missense	possibly damaging	0.67
R9564:Spata32	UTSW	11	103,099,779 (GRCm39)	missense	possibly damaging	0.89

Posted On

2015-04-16