Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02734:Gm12695'

305578

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm12695

Ensembl Gene

ENSMUSG00000078639

Gene Name

predicted gene 12695

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.073) question?

Stock #

IGL02734

Quality Score

Status

Chromosome

Chromosomal Location

96611884-96673423 bp(-) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

G to A at 96612267 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Stop codon at position 499 (R499*)

Ref Sequence

ENSEMBL: ENSMUSP00000102686 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000107071]

AlphaFold

A2AGB2

Predicted Effect

probably null
Transcript: ENSMUST00000107071
AA Change: R499*

SMART Domains

Protein: ENSMUSP00000102686
Gene: ENSMUSG00000078639
AA Change: R499*

Domain	Start	End	E-Value	Type
low complexity region	226	237	N/A	INTRINSIC
low complexity region	360	371	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 26 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aadacl4fm5	T	A	4: 144,506,349 (GRCm39)	D114V	probably damaging	Het
Adam26a	A	G	8: 44,022,812 (GRCm39)	V226A	probably benign	Het
Anapc4	T	A	5: 53,018,633 (GRCm39)	V525E	probably benign	Het
Apip	C	T	2: 102,919,889 (GRCm39)		probably benign	Het
Bak1	A	G	17: 27,239,927 (GRCm39)	V203A	possibly damaging	Het
Bche	T	A	3: 73,609,409 (GRCm39)	T6S	probably benign	Het
Ceacam5	T	A	7: 17,484,737 (GRCm39)	V493D	probably damaging	Het
Cstf3	T	A	2: 104,439,539 (GRCm39)		probably benign	Het
Fam227a	A	T	15: 79,502,042 (GRCm39)		probably benign	Het
Fbln1	G	T	15: 85,111,182 (GRCm39)	C112F	probably damaging	Het
Igdcc4	T	G	9: 65,038,738 (GRCm39)	S887A	possibly damaging	Het
Itgb4	G	T	11: 115,896,792 (GRCm39)	R1470L	probably benign	Het
Kif1a	T	C	1: 92,990,280 (GRCm39)	E480G	probably damaging	Het
Mgam	T	A	6: 40,639,628 (GRCm39)	F497L	probably damaging	Het
Or4a74	T	C	2: 89,440,303 (GRCm39)	I48V	probably benign	Het
Or5ar1	T	G	2: 85,671,883 (GRCm39)	D84A	possibly damaging	Het
Or5t5	T	C	2: 86,616,712 (GRCm39)	Y213H	probably benign	Het
Prl7a2	A	T	13: 27,843,190 (GRCm39)	D204E	probably benign	Het
Shd	A	G	17: 56,278,632 (GRCm39)	Y65C	probably damaging	Het
Slc25a39	A	G	11: 102,295,349 (GRCm39)	V207A	probably benign	Het
Sptlc2	T	C	12: 87,402,444 (GRCm39)	T161A	probably damaging	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
Tacc2	G	T	7: 130,227,829 (GRCm39)	V1505L	probably damaging	Het
Taf6	T	C	5: 138,182,118 (GRCm39)	K76E	possibly damaging	Het
Trak2	G	A	1: 58,949,222 (GRCm39)	T526M	probably benign	Het
Zc3h4	T	C	7: 16,157,849 (GRCm39)	I353T	unknown	Het

Other mutations in Gm12695

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00672:Gm12695	APN	4	96,637,419 (GRCm39)	missense	probably damaging	1.00
IGL01016:Gm12695	APN	4	96,646,184 (GRCm39)	missense	probably benign	0.03
IGL02605:Gm12695	APN	4	96,650,988 (GRCm39)	missense	probably null	0.92
IGL02869:Gm12695	APN	4	96,650,370 (GRCm39)	splice site	probably benign
IGL02895:Gm12695	APN	4	96,612,186 (GRCm39)	missense	probably damaging	0.99
R0020:Gm12695	UTSW	4	96,657,972 (GRCm39)	missense	probably damaging	0.96
R0465:Gm12695	UTSW	4	96,673,312 (GRCm39)	missense	probably damaging	1.00
R0941:Gm12695	UTSW	4	96,616,454 (GRCm39)	nonsense	probably null
R0968:Gm12695	UTSW	4	96,650,303 (GRCm39)	missense	probably damaging	1.00
R1965:Gm12695	UTSW	4	96,651,082 (GRCm39)	missense	probably benign	0.16
R1983:Gm12695	UTSW	4	96,627,214 (GRCm39)	missense	possibly damaging	0.84
R2051:Gm12695	UTSW	4	96,658,008 (GRCm39)	missense	probably damaging	0.99
R2063:Gm12695	UTSW	4	96,657,963 (GRCm39)	missense	probably benign	0.14
R2064:Gm12695	UTSW	4	96,657,963 (GRCm39)	missense	probably benign	0.14
R2065:Gm12695	UTSW	4	96,657,963 (GRCm39)	missense	probably benign	0.14
R2066:Gm12695	UTSW	4	96,657,963 (GRCm39)	missense	probably benign	0.14
R2067:Gm12695	UTSW	4	96,657,963 (GRCm39)	missense	probably benign	0.14
R2073:Gm12695	UTSW	4	96,612,182 (GRCm39)	missense	possibly damaging	0.76
R2075:Gm12695	UTSW	4	96,612,182 (GRCm39)	missense	possibly damaging	0.76
R2233:Gm12695	UTSW	4	96,612,266 (GRCm39)	missense	probably damaging	1.00
R2234:Gm12695	UTSW	4	96,612,266 (GRCm39)	missense	probably damaging	1.00
R2327:Gm12695	UTSW	4	96,657,893 (GRCm39)	missense	probably benign	0.00
R2507:Gm12695	UTSW	4	96,642,426 (GRCm39)	missense	probably damaging	0.99
R3836:Gm12695	UTSW	4	96,650,334 (GRCm39)	missense	probably damaging	0.99
R4685:Gm12695	UTSW	4	96,650,217 (GRCm39)	missense	probably damaging	1.00
R5491:Gm12695	UTSW	4	96,657,905 (GRCm39)	missense	possibly damaging	0.84
R5792:Gm12695	UTSW	4	96,616,520 (GRCm39)	missense	probably benign	0.00
R6767:Gm12695	UTSW	4	96,650,933 (GRCm39)	splice site	probably null
R6786:Gm12695	UTSW	4	96,651,058 (GRCm39)	missense	probably damaging	1.00
R6874:Gm12695	UTSW	4	96,673,306 (GRCm39)	missense	probably benign	0.04
R6923:Gm12695	UTSW	4	96,658,053 (GRCm39)	missense	probably benign	0.00
R6978:Gm12695	UTSW	4	96,657,959 (GRCm39)	missense	possibly damaging	0.69
R7810:Gm12695	UTSW	4	96,619,608 (GRCm39)	missense	probably damaging	0.99
R8263:Gm12695	UTSW	4	96,651,046 (GRCm39)	missense	probably benign	0.00
R8272:Gm12695	UTSW	4	96,612,183 (GRCm39)	missense	possibly damaging	0.76
R8285:Gm12695	UTSW	4	96,657,990 (GRCm39)	missense	possibly damaging	0.76
R8924:Gm12695	UTSW	4	96,651,046 (GRCm39)	missense	probably benign	0.00
R9115:Gm12695	UTSW	4	96,657,846 (GRCm39)	missense	possibly damaging	0.69
R9444:Gm12695	UTSW	4	96,612,195 (GRCm39)	missense	probably damaging	1.00
R9462:Gm12695	UTSW	4	96,651,075 (GRCm39)	missense	probably benign	0.26
R9725:Gm12695	UTSW	4	96,616,466 (GRCm39)	missense	probably damaging	1.00
Z1177:Gm12695	UTSW	4	96,637,460 (GRCm39)	missense	probably damaging	1.00

Posted On

2015-04-16