Incidental Mutation 'IGL02751:Gm4841'
ID306314
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm4841
Ensembl Gene ENSMUSG00000068606
Gene Namepredicted gene 4841
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.053) question?
Stock #IGL02751
Quality Score
Status
Chromosome18
Chromosomal Location60268301-60273267 bp(-) (GRCm38)
Type of Mutationutr 5 prime
DNA Base Change (assembly) A to G at 60271021 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000087727 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000090260]
Predicted Effect probably benign
Transcript: ENSMUST00000090260
SMART Domains Protein: ENSMUSP00000087727
Gene: ENSMUSG00000068606

DomainStartEndE-ValueType
Pfam:IIGP 36 409 1.2e-129 PFAM
Pfam:MMR_HSR1 72 185 2.2e-11 PFAM
Pfam:Roc 72 188 1.9e-8 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adra1a A T 14: 66,727,532 I324F possibly damaging Het
Ago2 G A 15: 73,130,897 A162V possibly damaging Het
Aox4 G T 1: 58,259,052 R1059I probably damaging Het
AU021092 C A 16: 5,212,619 V304L probably damaging Het
Bcs1l T G 1: 74,589,616 F20V probably damaging Het
Braf T C 6: 39,660,867 probably benign Het
Cacna1a T C 8: 84,569,952 C1200R probably damaging Het
Ccdc116 T A 16: 17,141,972 R284S probably benign Het
Cntnap5a T G 1: 116,184,457 probably null Het
Col12a1 A T 9: 79,613,859 probably benign Het
Cpa4 T A 6: 30,581,740 Y229N probably damaging Het
Fbp1 A C 13: 62,875,143 probably null Het
Gimap3 A T 6: 48,765,238 W253R probably benign Het
Gm1330 G A 2: 148,990,473 probably benign Het
Grip1 A G 10: 119,978,577 T338A probably benign Het
Hmg20b A T 10: 81,346,551 probably benign Het
Hnrnpdl A G 5: 100,037,974 F151L probably damaging Het
Klhl30 T A 1: 91,354,099 F141I probably damaging Het
Lamc3 T A 2: 31,920,704 F862Y probably benign Het
Lap3 T C 5: 45,504,796 C313R probably damaging Het
Lrp2 T C 2: 69,533,462 T344A possibly damaging Het
Mga A G 2: 119,947,770 E2023G possibly damaging Het
Mical2 A T 7: 112,332,036 K735N probably benign Het
Muc15 A G 2: 110,731,773 T185A probably benign Het
Olfr109 T C 17: 37,466,415 C70R probably damaging Het
Osbp2 T C 11: 3,863,434 K145R probably benign Het
Pde1c T C 6: 56,181,688 T52A probably damaging Het
Pidd1 A G 7: 141,439,163 S802P possibly damaging Het
Pip5k1c C A 10: 81,317,321 probably null Het
Prep T A 10: 45,115,186 I316N probably damaging Het
Prl3d2 G A 13: 27,126,031 probably null Het
Pygo1 A T 9: 72,945,037 I169F probably benign Het
Rnf10 G T 5: 115,242,666 A716E probably benign Het
Rtn4 G A 11: 29,706,409 probably null Het
Ryr1 A T 7: 29,078,774 V2099E probably damaging Het
Slc48a1 G A 15: 97,790,080 probably benign Het
Spag17 T A 3: 100,010,794 Y364* probably null Het
Syt3 A T 7: 44,386,062 D31V possibly damaging Het
Tango2 G T 16: 18,307,993 P143H probably benign Het
Tas2r104 A G 6: 131,685,144 S201P probably damaging Het
Tas2r107 G A 6: 131,659,484 L201F probably damaging Het
Vmn1r81 A T 7: 12,260,447 L78Q probably damaging Het
Vmn2r18 T A 5: 151,584,607 T351S probably benign Het
Other mutations in Gm4841
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01102:Gm4841 APN 18 60270052 missense probably damaging 1.00
IGL02043:Gm4841 APN 18 60270965 missense probably benign 0.05
R0277:Gm4841 UTSW 18 60270646 missense possibly damaging 0.83
R0323:Gm4841 UTSW 18 60270646 missense possibly damaging 0.83
R0616:Gm4841 UTSW 18 60270937 missense probably benign 0.00
R0882:Gm4841 UTSW 18 60269780 missense possibly damaging 0.92
R1778:Gm4841 UTSW 18 60270948 nonsense probably null
R2035:Gm4841 UTSW 18 60269857 missense probably benign 0.29
R2513:Gm4841 UTSW 18 60270905 missense probably damaging 1.00
R4242:Gm4841 UTSW 18 60270683 missense probably benign 0.05
R4295:Gm4841 UTSW 18 60270190 missense probably benign 0.01
R4574:Gm4841 UTSW 18 60269926 missense probably benign 0.02
R4720:Gm4841 UTSW 18 60270063 missense probably benign 0.00
R5273:Gm4841 UTSW 18 60270743 missense probably benign 0.00
R5314:Gm4841 UTSW 18 60270292 missense probably benign 0.13
R5378:Gm4841 UTSW 18 60271041 critical splice acceptor site probably null
R5902:Gm4841 UTSW 18 60270796 missense probably damaging 1.00
R5908:Gm4841 UTSW 18 60270434 missense possibly damaging 0.89
R6361:Gm4841 UTSW 18 60270760 missense probably damaging 1.00
R6677:Gm4841 UTSW 18 60270580 missense probably damaging 1.00
Posted On2015-04-16