Incidental Mutation 'R4012:Med1'
| ID |
311766 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Med1
|
| Ensembl Gene |
ENSMUSG00000018160 |
| Gene Name |
mediator complex subunit 1 |
| Synonyms |
DRIP205, TRAP220, PBP, Pparbp, CRSP210, l11Jus15, TRAP 220 |
| MMRRC Submission |
040949-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4012 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
98042980-98084119 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 98062532 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 189
(I189F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000103169
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000018304]
[ENSMUST00000092735]
[ENSMUST00000107545]
|
| AlphaFold |
Q925J9 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000018304
AA Change: I174F
PolyPhen 2
Score 0.847 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000018304
Gene: ENSMUSG00000018160
AA Change: I174F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med1
|
18 |
414 |
3.7e-112 |
PFAM |
|
low complexity region
|
536 |
559 |
N/A |
INTRINSIC |
|
low complexity region
|
595 |
619 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
678 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
981 |
N/A |
INTRINSIC |
|
low complexity region
|
989 |
999 |
N/A |
INTRINSIC |
|
low complexity region
|
1015 |
1036 |
N/A |
INTRINSIC |
|
low complexity region
|
1042 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1063 |
1138 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1183 |
N/A |
INTRINSIC |
|
low complexity region
|
1205 |
1243 |
N/A |
INTRINSIC |
|
low complexity region
|
1250 |
1281 |
N/A |
INTRINSIC |
|
low complexity region
|
1344 |
1364 |
N/A |
INTRINSIC |
|
low complexity region
|
1482 |
1503 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000092735
AA Change: I189F
PolyPhen 2
Score 0.349 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000090411
Gene: ENSMUSG00000018160
AA Change: I189F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med1
|
33 |
429 |
1.2e-113 |
PFAM |
|
transmembrane domain
|
585 |
607 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000107545
AA Change: I189F
PolyPhen 2
Score 0.847 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000103169
Gene: ENSMUSG00000018160
AA Change: I189F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med1
|
59 |
426 |
2.9e-74 |
PFAM |
|
low complexity region
|
551 |
574 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
634 |
N/A |
INTRINSIC |
|
low complexity region
|
682 |
693 |
N/A |
INTRINSIC |
|
low complexity region
|
975 |
996 |
N/A |
INTRINSIC |
|
low complexity region
|
1004 |
1014 |
N/A |
INTRINSIC |
|
low complexity region
|
1030 |
1051 |
N/A |
INTRINSIC |
|
low complexity region
|
1057 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1078 |
1153 |
N/A |
INTRINSIC |
|
low complexity region
|
1185 |
1198 |
N/A |
INTRINSIC |
|
low complexity region
|
1220 |
1258 |
N/A |
INTRINSIC |
|
low complexity region
|
1265 |
1296 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1379 |
N/A |
INTRINSIC |
|
low complexity region
|
1497 |
1518 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129557
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135479
|
| Meta Mutation Damage Score |
0.0774 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.0%
|
| Validation Efficiency |
100% (79/79) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for targeted null mutations have defects of placental vasculature, heart, and lens, arrested erythrocytic differentiation, impaired neuronal development, and die by embryonic day 11.5. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adnp2 |
G |
T |
18: 80,174,036 (GRCm39) |
F124L |
probably benign |
Het |
| Aicda |
A |
G |
6: 122,536,449 (GRCm39) |
K10E |
probably benign |
Het |
| Als2 |
A |
G |
1: 59,226,575 (GRCm39) |
C910R |
probably benign |
Het |
| Ankrd11 |
T |
A |
8: 123,619,156 (GRCm39) |
K1565N |
probably damaging |
Het |
| Apol7b |
T |
C |
15: 77,308,909 (GRCm39) |
D63G |
probably damaging |
Het |
| Arhgef4 |
T |
C |
1: 34,764,187 (GRCm39) |
C1148R |
possibly damaging |
Het |
| Atg16l1 |
A |
G |
1: 87,694,629 (GRCm39) |
D102G |
probably damaging |
Het |
| Babam2 |
T |
C |
5: 32,158,782 (GRCm39) |
V244A |
probably damaging |
Het |
| Brd10 |
T |
G |
19: 29,720,990 (GRCm39) |
K622N |
probably damaging |
Het |
| Cars1 |
G |
A |
7: 143,113,411 (GRCm39) |
A668V |
possibly damaging |
Het |
| Ccdc168 |
T |
C |
1: 44,100,129 (GRCm39) |
D323G |
possibly damaging |
Het |
| Ccdc185 |
T |
A |
1: 182,576,453 (GRCm39) |
S79C |
possibly damaging |
Het |
| Ccdc88b |
G |
C |
19: 6,826,359 (GRCm39) |
R1119G |
probably damaging |
Het |
| Cebpz |
A |
T |
17: 79,231,896 (GRCm39) |
V810E |
probably damaging |
Het |
| Cep120 |
T |
C |
18: 53,871,654 (GRCm39) |
T73A |
probably damaging |
Het |
| Chat |
C |
A |
14: 32,145,269 (GRCm39) |
C380F |
possibly damaging |
Het |
| Cltc |
T |
C |
11: 86,648,087 (GRCm39) |
Q10R |
probably benign |
Het |
| Cripto |
C |
T |
9: 110,769,781 (GRCm39) |
M169I |
probably benign |
Het |
| Cst8 |
T |
C |
2: 148,646,622 (GRCm39) |
|
probably benign |
Het |
| Cts3 |
C |
T |
13: 61,715,868 (GRCm39) |
|
probably null |
Het |
| Cyp4a29 |
T |
A |
4: 115,105,707 (GRCm39) |
D136E |
probably benign |
Het |
| Dmxl2 |
A |
C |
9: 54,286,297 (GRCm39) |
|
probably null |
Het |
| Dsg4 |
T |
A |
18: 20,584,919 (GRCm39) |
V211E |
possibly damaging |
Het |
| Efcab5 |
C |
T |
11: 77,008,656 (GRCm39) |
V957I |
probably damaging |
Het |
| Eif4g2 |
A |
T |
7: 110,673,358 (GRCm39) |
L807Q |
possibly damaging |
Het |
| Epha4 |
A |
G |
1: 77,366,731 (GRCm39) |
|
probably benign |
Het |
| Epm2aip1 |
A |
T |
9: 111,101,458 (GRCm39) |
I144F |
probably benign |
Het |
| Erbb4 |
C |
T |
1: 68,599,735 (GRCm39) |
R114H |
probably damaging |
Het |
| Fabp3 |
C |
T |
4: 130,206,180 (GRCm39) |
T57I |
probably benign |
Het |
| Fam170a |
C |
T |
18: 50,415,038 (GRCm39) |
A228V |
probably damaging |
Het |
| Foxred1 |
A |
T |
9: 35,117,571 (GRCm39) |
M254K |
possibly damaging |
Het |
| Gm1527 |
T |
A |
3: 28,952,969 (GRCm39) |
C90S |
probably benign |
Het |
| Gpr137b |
T |
C |
13: 13,533,947 (GRCm39) |
T370A |
probably benign |
Het |
| Gtf2e2 |
A |
G |
8: 34,245,993 (GRCm39) |
|
probably benign |
Het |
| Hgsnat |
A |
T |
8: 26,445,817 (GRCm39) |
L359* |
probably null |
Het |
| Hhip |
A |
T |
8: 80,719,223 (GRCm39) |
C435S |
probably damaging |
Het |
| Hoxa13 |
T |
C |
6: 52,236,107 (GRCm39) |
D310G |
possibly damaging |
Het |
| Hspa14 |
T |
C |
2: 3,513,675 (GRCm39) |
Y18C |
probably damaging |
Het |
| Ighg1 |
A |
G |
12: 113,293,270 (GRCm39) |
V140A |
probably damaging |
Het |
| Ighv1-58 |
A |
T |
12: 115,275,930 (GRCm39) |
Y69* |
probably null |
Het |
| Inpp5j |
A |
G |
11: 3,450,185 (GRCm39) |
F615L |
probably benign |
Het |
| Kcna1 |
T |
A |
6: 126,619,873 (GRCm39) |
Y149F |
probably benign |
Het |
| Kcnj6 |
A |
T |
16: 94,625,877 (GRCm39) |
|
probably null |
Het |
| Krtap4-1 |
G |
T |
11: 99,518,637 (GRCm39) |
C124* |
probably null |
Het |
| Lama1 |
T |
A |
17: 68,119,368 (GRCm39) |
L2615* |
probably null |
Het |
| Lcp2 |
A |
T |
11: 34,018,439 (GRCm39) |
I72F |
probably damaging |
Het |
| Meioc |
C |
T |
11: 102,566,654 (GRCm39) |
R757C |
probably damaging |
Het |
| Mtr |
T |
A |
13: 12,204,283 (GRCm39) |
H1171L |
probably damaging |
Het |
| Mtr |
G |
C |
13: 12,204,284 (GRCm39) |
H1171D |
probably damaging |
Het |
| Naa12 |
A |
G |
18: 80,255,339 (GRCm39) |
D211G |
probably benign |
Het |
| Nlrc5 |
A |
G |
8: 95,202,620 (GRCm39) |
Y240C |
possibly damaging |
Het |
| Nsun4 |
T |
A |
4: 115,908,259 (GRCm39) |
H767L |
possibly damaging |
Het |
| Pcdha1 |
T |
A |
18: 37,064,189 (GRCm39) |
N284K |
probably benign |
Het |
| Pcdhgb8 |
A |
C |
18: 37,896,414 (GRCm39) |
S495R |
probably benign |
Het |
| Pramel1 |
T |
A |
4: 143,123,260 (GRCm39) |
I79N |
possibly damaging |
Het |
| Prdm6 |
A |
T |
18: 53,673,390 (GRCm39) |
E183D |
possibly damaging |
Het |
| Prex2 |
T |
C |
1: 11,254,740 (GRCm39) |
F1125L |
probably benign |
Het |
| Prkg2 |
T |
C |
5: 99,127,674 (GRCm39) |
I346V |
possibly damaging |
Het |
| Ptprz1 |
A |
G |
6: 23,002,584 (GRCm39) |
D1558G |
probably damaging |
Het |
| Pttg1ip2 |
A |
C |
5: 5,528,955 (GRCm39) |
L20R |
probably damaging |
Het |
| Qng1 |
T |
A |
13: 58,529,800 (GRCm39) |
K271* |
probably null |
Het |
| Rab11fip3 |
GCTCGTCT |
GCT |
17: 26,287,002 (GRCm39) |
|
probably null |
Het |
| Rin2 |
C |
T |
2: 145,702,366 (GRCm39) |
T354I |
probably benign |
Het |
| S100a6 |
A |
G |
3: 90,521,508 (GRCm39) |
D50G |
probably damaging |
Het |
| Shroom3 |
T |
A |
5: 93,096,342 (GRCm39) |
|
probably benign |
Het |
| Sipa1l1 |
G |
A |
12: 82,388,556 (GRCm39) |
V261M |
possibly damaging |
Het |
| Slc5a4b |
T |
A |
10: 75,910,826 (GRCm39) |
I337F |
probably damaging |
Het |
| Smarcc1 |
A |
G |
9: 109,961,273 (GRCm39) |
Y30C |
possibly damaging |
Het |
| Swap70 |
A |
G |
7: 109,880,512 (GRCm39) |
K576E |
possibly damaging |
Het |
| Syt6 |
A |
G |
3: 103,532,809 (GRCm39) |
|
probably benign |
Het |
| Szt2 |
T |
C |
4: 118,241,097 (GRCm39) |
I1726V |
probably benign |
Het |
| Thoc1 |
A |
G |
18: 9,987,651 (GRCm39) |
K453E |
possibly damaging |
Het |
| Tmem38b |
A |
G |
4: 53,854,409 (GRCm39) |
I214V |
probably benign |
Het |
| Tonsl |
A |
T |
15: 76,521,244 (GRCm39) |
I354N |
probably damaging |
Het |
| Trappc9 |
T |
C |
15: 72,903,472 (GRCm39) |
I303V |
possibly damaging |
Het |
| Trim66 |
A |
G |
7: 109,057,338 (GRCm39) |
S1032P |
probably damaging |
Het |
| Tsc22d4 |
T |
C |
5: 137,756,590 (GRCm39) |
V6A |
probably benign |
Het |
| Ubtd2 |
A |
G |
11: 32,449,260 (GRCm39) |
K36E |
probably benign |
Het |
| Zkscan2 |
T |
C |
7: 123,097,883 (GRCm39) |
E171G |
possibly damaging |
Het |
|
| Other mutations in Med1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00556:Med1
|
APN |
11 |
98,046,510 (GRCm39) |
intron |
probably benign |
|
|
IGL00690:Med1
|
APN |
11 |
98,060,226 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01087:Med1
|
APN |
11 |
98,071,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01133:Med1
|
APN |
11 |
98,048,812 (GRCm39) |
nonsense |
probably null |
|
|
IGL02223:Med1
|
APN |
11 |
98,048,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02257:Med1
|
APN |
11 |
98,071,096 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02699:Med1
|
APN |
11 |
98,070,851 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL02706:Med1
|
APN |
11 |
98,047,533 (GRCm39) |
intron |
probably benign |
|
|
IGL02902:Med1
|
APN |
11 |
98,047,335 (GRCm39) |
intron |
probably benign |
|
|
IGL02986:Med1
|
APN |
11 |
98,047,086 (GRCm39) |
intron |
probably benign |
|
|
IGL03011:Med1
|
APN |
11 |
98,051,859 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03282:Med1
|
APN |
11 |
98,047,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03303:Med1
|
APN |
11 |
98,049,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03342:Med1
|
APN |
11 |
98,080,006 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03410:Med1
|
APN |
11 |
98,080,009 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
PIT4453001:Med1
|
UTSW |
11 |
98,049,243 (GRCm39) |
missense |
probably benign |
0.40 |
|
R0040:Med1
|
UTSW |
11 |
98,057,081 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0206:Med1
|
UTSW |
11 |
98,046,515 (GRCm39) |
intron |
probably benign |
|
|
R0206:Med1
|
UTSW |
11 |
98,046,515 (GRCm39) |
intron |
probably benign |
|
|
R0208:Med1
|
UTSW |
11 |
98,046,515 (GRCm39) |
intron |
probably benign |
|
|
R0310:Med1
|
UTSW |
11 |
98,058,400 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0505:Med1
|
UTSW |
11 |
98,047,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0597:Med1
|
UTSW |
11 |
98,060,264 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0680:Med1
|
UTSW |
11 |
98,070,992 (GRCm39) |
splice site |
probably null |
|
|
R0686:Med1
|
UTSW |
11 |
98,049,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0698:Med1
|
UTSW |
11 |
98,046,515 (GRCm39) |
intron |
probably benign |
|
|
R1293:Med1
|
UTSW |
11 |
98,047,862 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1302:Med1
|
UTSW |
11 |
98,048,275 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1365:Med1
|
UTSW |
11 |
98,046,821 (GRCm39) |
intron |
probably benign |
|
|
R1537:Med1
|
UTSW |
11 |
98,051,772 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1609:Med1
|
UTSW |
11 |
98,051,996 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1631:Med1
|
UTSW |
11 |
98,046,452 (GRCm39) |
intron |
probably benign |
|
|
R1792:Med1
|
UTSW |
11 |
98,048,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1831:Med1
|
UTSW |
11 |
98,047,437 (GRCm39) |
intron |
probably benign |
|
|
R1837:Med1
|
UTSW |
11 |
98,060,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2366:Med1
|
UTSW |
11 |
98,052,008 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3754:Med1
|
UTSW |
11 |
98,057,548 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R3762:Med1
|
UTSW |
11 |
98,046,341 (GRCm39) |
intron |
probably benign |
|
|
R4112:Med1
|
UTSW |
11 |
98,070,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4384:Med1
|
UTSW |
11 |
98,043,688 (GRCm39) |
unclassified |
probably benign |
|
|
R4579:Med1
|
UTSW |
11 |
98,049,248 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4740:Med1
|
UTSW |
11 |
98,071,090 (GRCm39) |
nonsense |
probably null |
|
|
R4819:Med1
|
UTSW |
11 |
98,046,258 (GRCm39) |
intron |
probably benign |
|
|
R4879:Med1
|
UTSW |
11 |
98,046,186 (GRCm39) |
unclassified |
probably benign |
|
|
R4993:Med1
|
UTSW |
11 |
98,054,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5040:Med1
|
UTSW |
11 |
98,046,230 (GRCm39) |
intron |
probably benign |
|
|
R5249:Med1
|
UTSW |
11 |
98,048,066 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5373:Med1
|
UTSW |
11 |
98,054,789 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5374:Med1
|
UTSW |
11 |
98,054,789 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5552:Med1
|
UTSW |
11 |
98,057,157 (GRCm39) |
nonsense |
probably null |
|
|
R5692:Med1
|
UTSW |
11 |
98,047,206 (GRCm39) |
intron |
probably benign |
|
|
R6010:Med1
|
UTSW |
11 |
98,049,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6149:Med1
|
UTSW |
11 |
98,074,679 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6417:Med1
|
UTSW |
11 |
98,048,054 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7301:Med1
|
UTSW |
11 |
98,043,634 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7507:Med1
|
UTSW |
11 |
98,048,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7529:Med1
|
UTSW |
11 |
98,046,791 (GRCm39) |
missense |
unknown |
|
|
R7588:Med1
|
UTSW |
11 |
98,046,398 (GRCm39) |
missense |
unknown |
|
|
R7654:Med1
|
UTSW |
11 |
98,060,189 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7662:Med1
|
UTSW |
11 |
98,046,218 (GRCm39) |
missense |
unknown |
|
|
R7679:Med1
|
UTSW |
11 |
98,046,887 (GRCm39) |
missense |
unknown |
|
|
R7862:Med1
|
UTSW |
11 |
98,052,036 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8447:Med1
|
UTSW |
11 |
98,060,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8693:Med1
|
UTSW |
11 |
98,046,599 (GRCm39) |
missense |
unknown |
|
|
R8843:Med1
|
UTSW |
11 |
98,080,102 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9072:Med1
|
UTSW |
11 |
98,080,009 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9284:Med1
|
UTSW |
11 |
98,046,366 (GRCm39) |
missense |
unknown |
|
|
R9428:Med1
|
UTSW |
11 |
98,080,049 (GRCm39) |
nonsense |
probably null |
|
|
R9465:Med1
|
UTSW |
11 |
98,049,144 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9531:Med1
|
UTSW |
11 |
98,048,321 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9537:Med1
|
UTSW |
11 |
98,062,586 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R9548:Med1
|
UTSW |
11 |
98,070,884 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9680:Med1
|
UTSW |
11 |
98,071,114 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9696:Med1
|
UTSW |
11 |
98,061,772 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1176:Med1
|
UTSW |
11 |
98,052,009 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAAGCAACAGCAAATCATAATTGTG -3'
(R):5'- CCCATGTGCTGAGATTATCCTG -3'
Sequencing Primer
(F):5'- CGCATATACTGTAGTACACCTAT -3'
(R):5'- GGGTCTCACTGAGTAACCTCAACTG -3'
|
| Posted On |
2015-04-29 |
Incidental Mutation