Mutagenetix > Incidental Mutation

Incidental Mutation 'R4120:Vmn2r129'

315264

Institutional Source

Beutler Lab

Gene Symbol

Vmn2r129

Ensembl Gene

ENSMUSG00000057021

Gene Name

vomeronasal 2, receptor 129

Synonyms

Vmn2r-ps160, Vmn2r-ps159, V2r9, V2r8

MMRRC Submission

040993-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.701) question?

Stock #

R4120 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

156683398-156691794 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

G to T at 156686778 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

A0A3Q4EIC8

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000074107

SMART Domains

Protein: ENSMUSP00000128975
Gene: ENSMUSG00000057021

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Pfam:ANF_receptor	76	423	1.4e-32	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000096792

SMART Domains

Protein: ENSMUSP00000094554
Gene: ENSMUSG00000057021

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Pfam:ANF_receptor	76	441	3.7e-31	PFAM
Pfam:NCD3G	510	563	1.4e-20	PFAM
Pfam:7tm_3	596	831	1.9e-56	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000189559

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.2%
20x: 95.0%

Validation Efficiency

93% (55/59)

Allele List at MGI

Other mutations in this stock

Total: 53 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrb3	C	A	1: 25,133,388 (GRCm39)	E1233*	probably null	Het
Afap1l1	T	C	18: 61,872,243 (GRCm39)	D526G	probably damaging	Het
Ago4	A	G	4: 126,390,600 (GRCm39)	Y807H	probably damaging	Het
Ankfy1	G	A	11: 72,605,310 (GRCm39)		probably null	Het
Arhgap40	A	G	2: 158,374,250 (GRCm39)	M222V	probably benign	Het
Asnsd1	A	G	1: 53,387,154 (GRCm39)	S158P	probably damaging	Het
Cdh15	T	C	8: 123,590,162 (GRCm39)	V365A	probably damaging	Het
Clca3a2	T	C	3: 144,516,613 (GRCm39)	M328V	probably benign	Het
Col4a1	G	A	8: 11,256,263 (GRCm39)	P1535S	unknown	Het
Dennd2a	G	A	6: 39,442,030 (GRCm39)	R947C	probably damaging	Het
Dlg2	G	A	7: 91,614,846 (GRCm39)	V217I	probably damaging	Het
Dnaaf2	T	C	12: 69,244,812 (GRCm39)	D83G	possibly damaging	Het
Dppa5a	A	T	9: 78,275,137 (GRCm39)	M55K	possibly damaging	Het
Ect2l	A	G	10: 18,006,466 (GRCm39)	V779A	probably benign	Het
Ehhadh	A	G	16: 21,581,934 (GRCm39)	S353P	probably benign	Het
Etv3	A	G	3: 87,443,589 (GRCm39)	D391G	probably benign	Het
Fastkd1	T	A	2: 69,537,654 (GRCm39)	K309N	probably damaging	Het
Fip1l1	T	A	5: 74,748,852 (GRCm39)	Y375N	probably damaging	Het
Flvcr2	T	C	12: 85,832,903 (GRCm39)	S308P	probably benign	Het
Fyco1	T	C	9: 123,654,691 (GRCm39)	Y1065C	probably benign	Het
Gfra2	A	G	14: 71,203,715 (GRCm39)	D31G	probably damaging	Het
Gm17175	A	T	14: 51,810,534 (GRCm39)	I31N	probably damaging	Het
Gm6003	T	A	7: 32,864,976 (GRCm39)		noncoding transcript	Het
Gm9951	T	C	8: 34,522,993 (GRCm39)		noncoding transcript	Het
Hspa2	A	G	12: 76,452,008 (GRCm39)	E234G	probably damaging	Het
Ip6k2	G	A	9: 108,682,847 (GRCm39)	R319Q	probably benign	Het
Iqsec1	A	T	6: 90,639,584 (GRCm39)	Y1065*	probably null	Het
Ltk	T	A	2: 119,588,429 (GRCm39)		probably benign	Het
Map2	G	A	1: 66,455,063 (GRCm39)	A1318T	probably damaging	Het
Mas1	A	T	17: 13,061,233 (GRCm39)	N63K	probably damaging	Het
Myo15b	T	C	11: 115,764,318 (GRCm39)	S1311P	probably benign	Het
Nav3	A	G	10: 109,739,605 (GRCm39)		probably null	Het
Nlrp1c-ps	T	C	11: 71,133,359 (GRCm39)		noncoding transcript	Het
Oca2	A	T	7: 55,904,630 (GRCm39)	D32V	probably damaging	Het
Or51v8	T	C	7: 103,320,221 (GRCm39)	T6A	probably benign	Het
Or8b9	T	C	9: 37,766,705 (GRCm39)	L197S	possibly damaging	Het
Otub2	T	C	12: 103,370,489 (GRCm39)	V257A	probably damaging	Het
Pink1	G	A	4: 138,042,822 (GRCm39)	R461*	probably null	Het
Plxna2	T	C	1: 194,462,935 (GRCm39)	C901R	probably damaging	Het
Ptchd3	T	A	11: 121,721,572 (GRCm39)	N148K	probably damaging	Het
Ralgapa1	C	T	12: 55,687,429 (GRCm39)	R2019Q	probably damaging	Het
Ripor1	T	A	8: 106,345,489 (GRCm39)		probably benign	Het
Sec13	T	C	6: 113,711,637 (GRCm39)	N107S	probably damaging	Het
Slc12a2	A	G	18: 58,032,427 (GRCm39)	M376V	possibly damaging	Het
Sp140l2	C	T	1: 85,237,542 (GRCm39)	V81M	possibly damaging	Het
Sptbn5	T	A	2: 119,895,010 (GRCm39)	D798V	possibly damaging	Het
Stradb	T	A	1: 59,019,168 (GRCm39)	Y30N	possibly damaging	Het
Syne1	T	A	10: 5,359,798 (GRCm39)	Q328L	probably damaging	Het
Ttc23l	A	C	15: 10,540,006 (GRCm39)	V159G	probably damaging	Het
Vmn2r100	T	C	17: 19,752,215 (GRCm39)	S753P	probably damaging	Het
Vmn2r39	G	A	7: 9,026,673 (GRCm39)	H443Y	probably benign	Het
Zfp936	A	G	7: 42,839,630 (GRCm39)	T366A	probably benign	Het
Zkscan3	T	C	13: 21,578,119 (GRCm39)	E256G	possibly damaging	Het

Other mutations in Vmn2r129

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL00977:Vmn2r129	APN	4	156,686,491 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,686,692 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,686,558 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,690,755 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,690,730 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,690,441 (GRCm39)	splice site	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,690,779 (GRCm39)	exon	noncoding transcript
IGL00990:Vmn2r129	APN	4	156,686,857 (GRCm39)	exon	noncoding transcript
IGL01018:Vmn2r129	APN	4	156,687,885 (GRCm39)	intron	noncoding transcript
IGL01018:Vmn2r129	APN	4	156,686,558 (GRCm39)	exon	noncoding transcript
IGL01018:Vmn2r129	APN	4	156,690,730 (GRCm39)	exon	noncoding transcript
IGL01018:Vmn2r129	APN	4	156,690,441 (GRCm39)	splice site	noncoding transcript
IGL01018:Vmn2r129	APN	4	156,686,900 (GRCm39)	exon	noncoding transcript
IGL01829:Vmn2r129	APN	4	156,685,614 (GRCm39)	intron	noncoding transcript
IGL01863:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01864:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01865:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01866:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01868:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01869:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01872:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01873:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01876:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01877:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01878:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01879:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01880:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01884:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01885:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01886:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01887:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01888:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01890:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01891:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01893:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01894:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01896:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01897:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01898:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01899:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01901:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01902:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01903:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01904:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01905:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01906:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01907:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01908:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01909:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01913:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01915:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01916:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01917:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01918:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01919:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01920:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01921:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01922:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01923:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01927:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01928:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01929:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01930:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01931:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01932:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01935:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01937:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01939:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01941:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01942:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01944:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01945:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01946:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01949:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01953:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01954:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01956:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL01957:Vmn2r129	APN	4	156,690,549 (GRCm39)	exon	noncoding transcript
IGL02270:Vmn2r129	APN	4	156,686,950 (GRCm39)	exon	noncoding transcript
R1746:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R1870:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R2147:Vmn2r129	UTSW	4	156,687,014 (GRCm39)	critical splice donor site	noncoding transcript
R2168:Vmn2r129	UTSW	4	156,690,673 (GRCm39)	exon	noncoding transcript
R2345:Vmn2r129	UTSW	4	156,689,334 (GRCm39)	splice site	noncoding transcript
R2510:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R2899:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R3106:Vmn2r129	UTSW	4	156,685,730 (GRCm39)	intron	noncoding transcript
R3122:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R3405:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R3430:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R3732:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R3751:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R4108:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R4112:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R4135:Vmn2r129	UTSW	4	156,691,085 (GRCm39)	exon	noncoding transcript
R4302:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R4475:Vmn2r129	UTSW	4	156,691,085 (GRCm39)	exon	noncoding transcript
R4840:Vmn2r129	UTSW	4	156,685,733 (GRCm39)	intron	noncoding transcript
R4872:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R5144:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R5271:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript
R5625:Vmn2r129	UTSW	4	156,686,505 (GRCm39)	exon	noncoding transcript
R5775:Vmn2r129	UTSW	4	156,686,692 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- AACCTCACAATGGGATGTCATC -3'
(R):5'- GACAAGCAGTGAAATATCTTTTGGG -3'

Sequencing Primer
(F):5'- CTTTTGCACACCACAGAG -3'
(R):5'- CAGTGAAATATCTTTTGGGTTTTGCC -3'

Posted On

2015-05-14