Incidental Mutation 'R0391:Ift172'
| ID |
31674 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ift172
|
| Ensembl Gene |
ENSMUSG00000038564 |
| Gene Name |
intraflagellar transport 172 |
| Synonyms |
4930553F24Rik, wim, avc1 |
| MMRRC Submission |
038597-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0391 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
31410623-31448458 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 31444011 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 69
(V69A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000049335
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041565]
[ENSMUST00000201809]
|
| AlphaFold |
Q6VH22 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041565
AA Change: V69A
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000049335
Gene: ENSMUSG00000038564
AA Change: V69A
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
44 |
6e-3 |
SMART |
|
WD40
|
55 |
94 |
2.22e0 |
SMART |
|
WD40
|
102 |
139 |
1.23e2 |
SMART |
|
WD40
|
141 |
180 |
4.6e0 |
SMART |
|
WD40
|
186 |
223 |
3.3e1 |
SMART |
|
WD40
|
225 |
267 |
4.42e1 |
SMART |
|
WD40
|
279 |
314 |
1.03e1 |
SMART |
|
Blast:WD40
|
516 |
550 |
5e-13 |
BLAST |
|
low complexity region
|
573 |
588 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
625 |
1026 |
1.7e-10 |
PROSPERO |
|
Blast:TPR
|
1029 |
1062 |
2e-13 |
BLAST |
|
low complexity region
|
1077 |
1091 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1101 |
1498 |
1.7e-10 |
PROSPERO |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201274
|
| Predicted Effect |
silent
Transcript: ENSMUST00000201809
|
| SMART Domains |
Protein: ENSMUSP00000144425
Gene: ENSMUSG00000038564
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
44 |
3.8e-5 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202410
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 95.9%
- 20x: 91.8%
|
| Validation Efficiency |
97% (97/100) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the intraflagellar transport subcomplex IFT-B. Subcomplexes IFT-A and IFT-B are necessary for ciliary assembly and maintenance. Mutations in this gene have been associated with skeletal ciliopathies, with or without polydactyly, such as such short-rib thoracic dysplasias 1, 9 or 10. [provided by RefSeq, Mar 2014]
PHENOTYPE: Mice homozygous for disruptions in this gene display embryonic lethality during organogenesis, neural tube defects, and developmental patterning abnormalities. Mice homozygous for a conditional allele activated in the early limb bud exhibit polydactyly and short limbs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9530002B09Rik |
T |
A |
4: 122,594,970 (GRCm39) |
|
probably benign |
Het |
| Abcc2 |
G |
A |
19: 43,810,044 (GRCm39) |
|
probably benign |
Het |
| Abcc8 |
C |
G |
7: 45,771,597 (GRCm39) |
G838A |
probably damaging |
Het |
| Akr1c21 |
G |
A |
13: 4,631,199 (GRCm39) |
A245T |
probably damaging |
Het |
| Anapc15-ps |
T |
C |
10: 95,509,139 (GRCm39) |
E47G |
probably damaging |
Het |
| Apoa1 |
A |
G |
9: 46,141,140 (GRCm39) |
T79A |
probably benign |
Het |
| Atp6v1b1 |
A |
G |
6: 83,733,903 (GRCm39) |
H378R |
possibly damaging |
Het |
| C4b |
A |
G |
17: 34,954,588 (GRCm39) |
|
probably benign |
Het |
| Catsperd |
A |
T |
17: 56,969,821 (GRCm39) |
E638D |
probably benign |
Het |
| Cckar |
C |
T |
5: 53,863,595 (GRCm39) |
|
probably null |
Het |
| Cfap100 |
C |
T |
6: 90,382,321 (GRCm39) |
|
probably benign |
Het |
| Chd1 |
G |
T |
17: 15,970,156 (GRCm39) |
G970C |
probably damaging |
Het |
| Col14a1 |
A |
G |
15: 55,309,655 (GRCm39) |
|
probably benign |
Het |
| Col17a1 |
C |
T |
19: 47,652,263 (GRCm39) |
V698M |
probably damaging |
Het |
| Cpeb1 |
T |
C |
7: 81,011,473 (GRCm39) |
D156G |
possibly damaging |
Het |
| Cryl1 |
A |
G |
14: 57,541,232 (GRCm39) |
Y151H |
possibly damaging |
Het |
| Csmd3 |
C |
A |
15: 47,520,969 (GRCm39) |
V1881L |
probably damaging |
Het |
| Ctnnal1 |
C |
T |
4: 56,847,921 (GRCm39) |
A73T |
probably damaging |
Het |
| Cyp2c37 |
T |
C |
19: 39,982,950 (GRCm39) |
S180P |
probably damaging |
Het |
| Cyp2c54 |
T |
C |
19: 40,060,613 (GRCm39) |
T123A |
possibly damaging |
Het |
| Dennd6b |
T |
C |
15: 89,071,417 (GRCm39) |
D304G |
probably damaging |
Het |
| Dnmt3l |
T |
C |
10: 77,887,750 (GRCm39) |
|
probably benign |
Het |
| Eci1 |
G |
A |
17: 24,652,234 (GRCm39) |
|
probably null |
Het |
| Efhc1 |
A |
G |
1: 21,030,412 (GRCm39) |
Y115C |
probably damaging |
Het |
| Ern1 |
T |
A |
11: 106,298,004 (GRCm39) |
K706* |
probably null |
Het |
| Ghrl |
T |
C |
6: 113,696,299 (GRCm39) |
E31G |
probably damaging |
Het |
| Gpr108 |
A |
C |
17: 57,550,101 (GRCm39) |
V179G |
probably benign |
Het |
| Henmt1 |
A |
G |
3: 108,865,851 (GRCm39) |
|
probably benign |
Het |
| Il17ra |
T |
C |
6: 120,453,940 (GRCm39) |
|
probably benign |
Het |
| Il17rb |
T |
C |
14: 29,726,304 (GRCm39) |
N95D |
probably benign |
Het |
| Il17rb |
G |
T |
14: 29,728,112 (GRCm39) |
|
probably null |
Het |
| Iqub |
G |
A |
6: 24,446,154 (GRCm39) |
L757F |
probably benign |
Het |
| Itpr1 |
T |
C |
6: 108,355,128 (GRCm39) |
V473A |
probably benign |
Het |
| Itpr2 |
T |
G |
6: 146,131,271 (GRCm39) |
N1978H |
probably damaging |
Het |
| Klk1b26 |
T |
A |
7: 43,662,151 (GRCm39) |
F3Y |
probably damaging |
Het |
| Lars1 |
A |
G |
18: 42,384,428 (GRCm39) |
V50A |
probably benign |
Het |
| Lax1 |
G |
T |
1: 133,607,804 (GRCm39) |
H312Q |
probably benign |
Het |
| Lctl |
T |
C |
9: 64,029,596 (GRCm39) |
|
probably benign |
Het |
| Lrp2 |
T |
A |
2: 69,287,202 (GRCm39) |
D3745V |
probably damaging |
Het |
| Lrp2 |
G |
A |
2: 69,290,681 (GRCm39) |
|
probably benign |
Het |
| Lvrn |
A |
T |
18: 46,983,533 (GRCm39) |
H92L |
probably benign |
Het |
| Marchf1 |
A |
G |
8: 66,871,625 (GRCm39) |
T385A |
probably damaging |
Het |
| Marf1 |
C |
T |
16: 13,960,398 (GRCm39) |
A549T |
probably damaging |
Het |
| Mbd5 |
T |
C |
2: 49,162,428 (GRCm39) |
V970A |
possibly damaging |
Het |
| Mccc1 |
A |
G |
3: 36,017,719 (GRCm39) |
|
probably benign |
Het |
| Mpp4 |
A |
T |
1: 59,182,988 (GRCm39) |
|
probably benign |
Het |
| Mrnip |
G |
A |
11: 50,090,747 (GRCm39) |
A304T |
probably damaging |
Het |
| Muc5b |
T |
C |
7: 141,418,819 (GRCm39) |
S3922P |
possibly damaging |
Het |
| Myh3 |
T |
A |
11: 66,987,333 (GRCm39) |
|
probably benign |
Het |
| Nbea |
A |
T |
3: 55,944,698 (GRCm39) |
H555Q |
probably damaging |
Het |
| Niban3 |
T |
A |
8: 72,055,143 (GRCm39) |
|
probably benign |
Het |
| Nlrp9c |
A |
T |
7: 26,070,901 (GRCm39) |
|
probably benign |
Het |
| Nmur1 |
A |
T |
1: 86,315,400 (GRCm39) |
V178E |
probably damaging |
Het |
| Nod2 |
T |
G |
8: 89,390,406 (GRCm39) |
S238A |
probably benign |
Het |
| Ogfod1 |
A |
T |
8: 94,789,651 (GRCm39) |
T451S |
probably damaging |
Het |
| Or1e17 |
T |
C |
11: 73,831,935 (GRCm39) |
F288L |
probably damaging |
Het |
| Or2d36 |
T |
A |
7: 106,747,394 (GRCm39) |
Y290* |
probably null |
Het |
| Or2z8 |
C |
T |
8: 72,812,244 (GRCm39) |
T240M |
probably damaging |
Het |
| Or8b8 |
G |
A |
9: 37,809,138 (GRCm39) |
G146D |
probably benign |
Het |
| Pcdh20 |
T |
C |
14: 88,706,104 (GRCm39) |
I399V |
probably benign |
Het |
| Pdlim1 |
G |
T |
19: 40,232,017 (GRCm39) |
H120Q |
probably damaging |
Het |
| Plg |
T |
C |
17: 12,637,968 (GRCm39) |
V798A |
probably damaging |
Het |
| Polr2c |
A |
G |
8: 95,584,403 (GRCm39) |
I39V |
possibly damaging |
Het |
| Ppfia2 |
C |
A |
10: 106,666,575 (GRCm39) |
|
probably benign |
Het |
| Ppp1r3a |
A |
T |
6: 14,719,696 (GRCm39) |
I406N |
probably benign |
Het |
| Psg28 |
A |
T |
7: 18,160,098 (GRCm39) |
M366K |
probably benign |
Het |
| Rad54b |
T |
C |
4: 11,601,702 (GRCm39) |
I419T |
probably damaging |
Het |
| Rnf43 |
A |
G |
11: 87,622,108 (GRCm39) |
Q403R |
possibly damaging |
Het |
| Sema6a |
G |
A |
18: 47,423,112 (GRCm39) |
|
probably null |
Het |
| Slc28a3 |
A |
G |
13: 58,717,229 (GRCm39) |
|
probably benign |
Het |
| Smad2 |
A |
T |
18: 76,422,108 (GRCm39) |
|
probably null |
Het |
| Smad4 |
G |
A |
18: 73,791,720 (GRCm39) |
P274S |
probably benign |
Het |
| Smchd1 |
A |
T |
17: 71,710,149 (GRCm39) |
V906D |
probably damaging |
Het |
| Soat2 |
C |
A |
15: 102,067,188 (GRCm39) |
R320S |
possibly damaging |
Het |
| Spata33 |
C |
T |
8: 123,948,626 (GRCm39) |
A57V |
probably damaging |
Het |
| Stab1 |
A |
G |
14: 30,865,375 (GRCm39) |
L1814P |
probably benign |
Het |
| Stab2 |
T |
C |
10: 86,783,008 (GRCm39) |
K680R |
probably benign |
Het |
| Stil |
A |
G |
4: 114,898,369 (GRCm39) |
|
probably null |
Het |
| Sympk |
T |
A |
7: 18,780,774 (GRCm39) |
L759H |
probably benign |
Het |
| Tet1 |
A |
T |
10: 62,650,325 (GRCm39) |
|
probably null |
Het |
| Tfpi2 |
A |
T |
6: 3,965,460 (GRCm39) |
N117K |
probably benign |
Het |
| Tle3 |
A |
G |
9: 61,323,943 (GRCm39) |
Y766C |
probably damaging |
Het |
| Trpt1 |
C |
A |
19: 6,975,298 (GRCm39) |
|
probably null |
Het |
| Tshz1 |
A |
G |
18: 84,034,174 (GRCm39) |
F78S |
possibly damaging |
Het |
| Ttc1 |
T |
C |
11: 43,629,635 (GRCm39) |
D177G |
probably damaging |
Het |
| Ttc13 |
T |
A |
8: 125,401,140 (GRCm39) |
Y741F |
probably damaging |
Het |
| Ulk3 |
C |
T |
9: 57,502,115 (GRCm39) |
S462L |
probably benign |
Het |
| Utrn |
C |
T |
10: 12,401,077 (GRCm39) |
|
probably benign |
Het |
| V1rd19 |
A |
C |
7: 23,703,010 (GRCm39) |
T159P |
probably damaging |
Het |
| Vars1 |
T |
C |
17: 35,230,462 (GRCm39) |
V515A |
possibly damaging |
Het |
| Vmn1r85 |
A |
G |
7: 12,818,515 (GRCm39) |
Y210H |
probably benign |
Het |
| Vmn2r89 |
A |
G |
14: 51,693,435 (GRCm39) |
T262A |
probably damaging |
Het |
| Vps53 |
G |
A |
11: 76,012,405 (GRCm39) |
T209I |
probably benign |
Het |
| Wdfy2 |
T |
C |
14: 63,162,582 (GRCm39) |
F95L |
possibly damaging |
Het |
| Wwp1 |
G |
T |
4: 19,627,911 (GRCm39) |
S694Y |
probably damaging |
Het |
| Zbtb8b |
T |
A |
4: 129,326,463 (GRCm39) |
D201V |
probably damaging |
Het |
| Zmym5 |
A |
C |
14: 57,041,908 (GRCm39) |
N123K |
possibly damaging |
Het |
|
| Other mutations in Ift172 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Ift172
|
APN |
5 |
31,433,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01399:Ift172
|
APN |
5 |
31,423,592 (GRCm39) |
missense |
probably benign |
|
|
IGL01405:Ift172
|
APN |
5 |
31,419,196 (GRCm39) |
nonsense |
probably null |
|
|
IGL01562:Ift172
|
APN |
5 |
31,424,591 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01758:Ift172
|
APN |
5 |
31,438,058 (GRCm39) |
missense |
probably benign |
|
|
IGL01792:Ift172
|
APN |
5 |
31,434,215 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01830:Ift172
|
APN |
5 |
31,442,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01839:Ift172
|
APN |
5 |
31,423,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02007:Ift172
|
APN |
5 |
31,443,948 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02172:Ift172
|
APN |
5 |
31,438,681 (GRCm39) |
splice site |
probably benign |
|
|
IGL02190:Ift172
|
APN |
5 |
31,411,802 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL02334:Ift172
|
APN |
5 |
31,440,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02486:Ift172
|
APN |
5 |
31,414,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02517:Ift172
|
APN |
5 |
31,410,992 (GRCm39) |
splice site |
probably null |
|
|
IGL02571:Ift172
|
APN |
5 |
31,415,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Ift172
|
APN |
5 |
31,421,840 (GRCm39) |
missense |
probably benign |
|
|
IGL03183:Ift172
|
APN |
5 |
31,429,348 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03277:Ift172
|
APN |
5 |
31,424,642 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03349:Ift172
|
APN |
5 |
31,441,474 (GRCm39) |
missense |
probably benign |
0.05 |
|
ostinato
|
UTSW |
5 |
31,434,284 (GRCm39) |
missense |
probably benign |
0.10 |
|
pushback
|
UTSW |
5 |
31,444,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0042:Ift172
|
UTSW |
5 |
31,418,799 (GRCm39) |
missense |
probably benign |
0.35 |
|
PIT4802001:Ift172
|
UTSW |
5 |
31,442,610 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0153:Ift172
|
UTSW |
5 |
31,417,968 (GRCm39) |
missense |
probably benign |
|
|
R0328:Ift172
|
UTSW |
5 |
31,421,195 (GRCm39) |
nonsense |
probably null |
|
|
R0357:Ift172
|
UTSW |
5 |
31,415,244 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R0369:Ift172
|
UTSW |
5 |
31,410,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0512:Ift172
|
UTSW |
5 |
31,442,821 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0546:Ift172
|
UTSW |
5 |
31,414,945 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0553:Ift172
|
UTSW |
5 |
31,433,186 (GRCm39) |
splice site |
probably benign |
|
|
R0606:Ift172
|
UTSW |
5 |
31,411,657 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0834:Ift172
|
UTSW |
5 |
31,414,715 (GRCm39) |
missense |
probably benign |
|
|
R0973:Ift172
|
UTSW |
5 |
31,415,262 (GRCm39) |
unclassified |
probably benign |
|
|
R0973:Ift172
|
UTSW |
5 |
31,422,699 (GRCm39) |
missense |
probably benign |
|
|
R1189:Ift172
|
UTSW |
5 |
31,443,174 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1205:Ift172
|
UTSW |
5 |
31,443,136 (GRCm39) |
missense |
probably benign |
|
|
R1289:Ift172
|
UTSW |
5 |
31,438,320 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1342:Ift172
|
UTSW |
5 |
31,419,210 (GRCm39) |
missense |
probably benign |
|
|
R1395:Ift172
|
UTSW |
5 |
31,442,582 (GRCm39) |
unclassified |
probably benign |
|
|
R1417:Ift172
|
UTSW |
5 |
31,413,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2020:Ift172
|
UTSW |
5 |
31,424,585 (GRCm39) |
nonsense |
probably null |
|
|
R2111:Ift172
|
UTSW |
5 |
31,443,423 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2175:Ift172
|
UTSW |
5 |
31,424,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2509:Ift172
|
UTSW |
5 |
31,420,312 (GRCm39) |
missense |
probably benign |
|
|
R2870:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2870:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3705:Ift172
|
UTSW |
5 |
31,418,781 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3793:Ift172
|
UTSW |
5 |
31,414,925 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R4385:Ift172
|
UTSW |
5 |
31,444,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4477:Ift172
|
UTSW |
5 |
31,422,781 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4590:Ift172
|
UTSW |
5 |
31,411,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4663:Ift172
|
UTSW |
5 |
31,441,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4665:Ift172
|
UTSW |
5 |
31,442,598 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4977:Ift172
|
UTSW |
5 |
31,429,460 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5109:Ift172
|
UTSW |
5 |
31,423,330 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5182:Ift172
|
UTSW |
5 |
31,424,958 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5343:Ift172
|
UTSW |
5 |
31,421,156 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5465:Ift172
|
UTSW |
5 |
31,418,862 (GRCm39) |
splice site |
probably null |
|
|
R5622:Ift172
|
UTSW |
5 |
31,440,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Ift172
|
UTSW |
5 |
31,412,621 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5793:Ift172
|
UTSW |
5 |
31,434,292 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5870:Ift172
|
UTSW |
5 |
31,434,284 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5919:Ift172
|
UTSW |
5 |
31,418,006 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5968:Ift172
|
UTSW |
5 |
31,418,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6112:Ift172
|
UTSW |
5 |
31,414,241 (GRCm39) |
missense |
probably benign |
|
|
R6339:Ift172
|
UTSW |
5 |
31,444,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6339:Ift172
|
UTSW |
5 |
31,413,927 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6355:Ift172
|
UTSW |
5 |
31,441,501 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6565:Ift172
|
UTSW |
5 |
31,433,227 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6668:Ift172
|
UTSW |
5 |
31,412,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6755:Ift172
|
UTSW |
5 |
31,418,342 (GRCm39) |
nonsense |
probably null |
|
|
R6818:Ift172
|
UTSW |
5 |
31,423,304 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6939:Ift172
|
UTSW |
5 |
31,414,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6980:Ift172
|
UTSW |
5 |
31,414,730 (GRCm39) |
missense |
probably benign |
|
|
R7047:Ift172
|
UTSW |
5 |
31,433,238 (GRCm39) |
nonsense |
probably null |
|
|
R7156:Ift172
|
UTSW |
5 |
31,429,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Ift172
|
UTSW |
5 |
31,411,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Ift172
|
UTSW |
5 |
31,442,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7351:Ift172
|
UTSW |
5 |
31,433,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7706:Ift172
|
UTSW |
5 |
31,423,723 (GRCm39) |
nonsense |
probably null |
|
|
R7890:Ift172
|
UTSW |
5 |
31,440,425 (GRCm39) |
nonsense |
probably null |
|
|
R7980:Ift172
|
UTSW |
5 |
31,417,988 (GRCm39) |
missense |
probably benign |
|
|
R8263:Ift172
|
UTSW |
5 |
31,422,681 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8559:Ift172
|
UTSW |
5 |
31,413,921 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8717:Ift172
|
UTSW |
5 |
31,412,985 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8774:Ift172
|
UTSW |
5 |
31,415,207 (GRCm39) |
missense |
probably benign |
0.45 |
|
R8774-TAIL:Ift172
|
UTSW |
5 |
31,415,207 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9037:Ift172
|
UTSW |
5 |
31,420,400 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9038:Ift172
|
UTSW |
5 |
31,441,399 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9133:Ift172
|
UTSW |
5 |
31,442,867 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9607:Ift172
|
UTSW |
5 |
31,410,913 (GRCm39) |
missense |
|
|
|
X0022:Ift172
|
UTSW |
5 |
31,442,664 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1176:Ift172
|
UTSW |
5 |
31,434,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCTGATCCTGGCATCAAACCTCTG -3'
(R):5'- GTGCCCTGTGCCCTAAACTGTTAC -3'
Sequencing Primer
(F):5'- ACCCCAGTGAGGCATTTC -3'
(R):5'- CCCTAGAAAACTTTGTAATCTGCC -3'
|
| Posted On |
2013-04-24 |
Incidental Mutation