Mutagenetix > Incidental Mutation

Incidental Mutation 'R4105:Ptprq'

321359

Institutional Source

Beutler Lab

Gene Symbol

Ptprq

Ensembl Gene

ENSMUSG00000035916

Gene Name

protein tyrosine phosphatase receptor type Q

Synonyms

MMRRC Submission

040985-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.236) question?

Stock #

R4105 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

107352910-107555912 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 107408828 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Asparagine at position 1895 (T1895N)

Ref Sequence

ENSEMBL: ENSMUSP00000058572 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000050702]

AlphaFold

P0C5E4

Predicted Effect

probably damaging
Transcript: ENSMUST00000050702
AA Change: T1895N

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000058572
Gene: ENSMUSG00000035916
AA Change: T1895N

Domain	Start	End	E-Value	Type
FN3	57	141	3.17e-13	SMART
FN3	156	294	1.55e-7	SMART
FN3	307	384	4.45e-8	SMART
FN3	398	555	1.17e-7	SMART
FN3	569	648	7.06e-11	SMART
FN3	666	743	7.68e-12	SMART
FN3	760	839	1.88e-6	SMART
FN3	855	932	1.33e-6	SMART
FN3	949	1037	2.31e-6	SMART
FN3	1054	1135	1.24e-6	SMART
FN3	1151	1229	2.39e-8	SMART
FN3	1244	1325	6.29e-8	SMART
FN3	1341	1416	2.87e-11	SMART
FN3	1431	1524	2.82e-10	SMART
FN3	1540	1622	6.35e-4	SMART
FN3	1642	1732	7.93e-5	SMART
transmembrane domain	1907	1929	N/A	INTRINSIC
PTPc	2003	2262	1.14e-130	SMART

Meta Mutation Damage Score

0.1190

Coding Region Coverage

1x: 99.2%
3x: 98.7%
10x: 97.4%
20x: 95.7%

Validation Efficiency

96% (46/48)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes a member of the type III receptor-like protein-tyrosine phosphatase family. The encoded protein catalyzes the dephosphorylation of phosphotyrosine and phosphatidylinositol and plays roles in cellular proliferation and differentiation. Mutations at this locus have been linked to autosomal recessive deafness. [provided by RefSeq, Mar 2014]
PHENOTYPE: Homozygotes for targeted mutations show absence of shaft connectors from vestibular hair bundles, postnatal degeneration in cochlear hair-bundle structure, reduced transducer currents but otherwise normal adaptation properties, a progressive loss of basal-coil cochlear hair cells, and deafness. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adar	T	C	3: 89,647,401 (GRCm39)	S127P	probably benign	Het
Arhgap31	A	G	16: 38,422,788 (GRCm39)	S1093P	probably damaging	Het
Asb18	T	C	1: 89,896,243 (GRCm39)	S266G	possibly damaging	Het
Atg9a	A	G	1: 75,162,603 (GRCm39)	Y471H	probably damaging	Het
Atosa	A	G	9: 74,916,058 (GRCm39)	Q226R	probably damaging	Het
Bmper	G	A	9: 23,136,059 (GRCm39)	V47I	probably benign	Het
Cel	T	C	2: 28,448,039 (GRCm39)	D329G	probably benign	Het
Ces2f	T	C	8: 105,677,824 (GRCm39)		probably null	Het
Cyp2j7	T	C	4: 96,087,687 (GRCm39)	T408A	possibly damaging	Het
Dchs1	A	C	7: 105,414,347 (GRCm39)	S823A	probably damaging	Het
Dnajb2	G	T	1: 75,213,543 (GRCm39)	E6*	probably null	Het
Eif2b3	G	A	4: 116,938,831 (GRCm39)	G427R	probably damaging	Het
Eml5	T	C	12: 98,807,807 (GRCm39)		probably null	Het
Fat1	A	G	8: 45,489,888 (GRCm39)	Y3600C	probably damaging	Het
Fbxo10	A	G	4: 45,059,054 (GRCm39)	F228L	probably benign	Het
Fgf7	T	A	2: 125,877,599 (GRCm39)		probably benign	Het
Gm2832	A	T	14: 41,002,856 (GRCm39)	M122L	unknown	Het
Lrrcc1	T	C	3: 14,615,388 (GRCm39)	V73A	probably benign	Het
Mrc2	G	A	11: 105,239,257 (GRCm39)		probably null	Het
Naip5	T	C	13: 100,356,247 (GRCm39)	R1123G	probably benign	Het
Nfya	G	T	17: 48,699,912 (GRCm39)	Y37*	probably null	Het
Or2o1	A	G	11: 49,051,375 (GRCm39)	H178R	possibly damaging	Het
Pikfyve	A	G	1: 65,229,679 (GRCm39)		probably benign	Het
Pnma8a	T	C	7: 16,695,104 (GRCm39)	S320P	possibly damaging	Het
Polr1a	A	G	6: 71,953,175 (GRCm39)	N1581S	probably damaging	Het
Polrmt	G	T	10: 79,577,567 (GRCm39)	T344K	probably benign	Het
Postn	T	C	3: 54,283,462 (GRCm39)	F514L	probably damaging	Het
Slc15a2	G	T	16: 36,602,755 (GRCm39)		probably benign	Het
Slco2a1	T	A	9: 102,945,075 (GRCm39)	L150Q	probably benign	Het
Slco2a1	T	C	9: 102,950,449 (GRCm39)	F347S	probably damaging	Het
Smim13	T	A	13: 41,426,127 (GRCm39)	D54E	probably benign	Het
Snrnp200	T	A	2: 127,069,936 (GRCm39)	I1027N	probably damaging	Het
Sult6b1	G	T	17: 79,214,291 (GRCm39)	T6N	probably damaging	Het
Tas1r2	G	A	4: 139,387,363 (GRCm39)	R245H	probably benign	Het
Tpo	G	A	12: 30,142,585 (GRCm39)	P713L	probably damaging	Het
Trank1	T	C	9: 111,181,265 (GRCm39)	I429T	probably damaging	Het
Trip11	G	A	12: 101,860,581 (GRCm39)	R254*	probably null	Het
Vmn2r65	A	G	7: 84,595,691 (GRCm39)	V331A	probably benign	Het
Ypel3	T	C	7: 126,377,265 (GRCm39)	S82P	probably damaging	Het
Zfp128	T	C	7: 12,618,667 (GRCm39)	L55P	probably damaging	Het
Zscan4e	T	C	7: 11,041,437 (GRCm39)	D173G	probably benign	Het

Other mutations in Ptprq

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00340:Ptprq	APN	10	107,412,790 (GRCm39)	missense	probably damaging	0.98
IGL00537:Ptprq	APN	10	107,546,383 (GRCm39)	missense	probably benign	0.07
IGL00547:Ptprq	APN	10	107,554,402 (GRCm39)	missense	probably damaging	0.99
IGL00586:Ptprq	APN	10	107,443,983 (GRCm39)	splice site	probably benign
IGL00648:Ptprq	APN	10	107,482,577 (GRCm39)	missense	probably benign	0.10
IGL01123:Ptprq	APN	10	107,522,079 (GRCm39)	missense	probably damaging	0.96
IGL01343:Ptprq	APN	10	107,474,700 (GRCm39)	missense	probably damaging	0.96
IGL01348:Ptprq	APN	10	107,547,765 (GRCm39)	missense	probably damaging	1.00
IGL01433:Ptprq	APN	10	107,412,741 (GRCm39)	missense	probably damaging	0.99
IGL01510:Ptprq	APN	10	107,547,909 (GRCm39)	missense	probably damaging	1.00
IGL01535:Ptprq	APN	10	107,535,457 (GRCm39)	missense	probably benign
IGL01631:Ptprq	APN	10	107,479,399 (GRCm39)	missense	probably benign	0.00
IGL01633:Ptprq	APN	10	107,535,584 (GRCm39)	splice site	probably benign
IGL01702:Ptprq	APN	10	107,353,727 (GRCm39)	missense	probably benign	0.00
IGL01733:Ptprq	APN	10	107,498,460 (GRCm39)	missense	probably benign	0.10
IGL01806:Ptprq	APN	10	107,535,469 (GRCm39)	missense	probably damaging	1.00
IGL01832:Ptprq	APN	10	107,401,700 (GRCm39)	critical splice donor site	probably null
IGL01961:Ptprq	APN	10	107,479,515 (GRCm39)	missense	probably damaging	1.00
IGL02108:Ptprq	APN	10	107,482,478 (GRCm39)	missense	probably damaging	1.00
IGL02120:Ptprq	APN	10	107,503,333 (GRCm39)	missense	probably damaging	1.00
IGL02160:Ptprq	APN	10	107,489,426 (GRCm39)	missense	probably benign	0.00
IGL02178:Ptprq	APN	10	107,522,180 (GRCm39)	missense	probably benign	0.03
IGL02249:Ptprq	APN	10	107,418,220 (GRCm39)	missense	probably damaging	1.00
IGL02267:Ptprq	APN	10	107,482,419 (GRCm39)	missense	probably damaging	1.00
IGL02527:Ptprq	APN	10	107,522,424 (GRCm39)	missense	probably benign	0.04
IGL02529:Ptprq	APN	10	107,471,226 (GRCm39)	missense	probably benign	0.03
IGL02542:Ptprq	APN	10	107,498,416 (GRCm39)	missense	probably damaging	1.00
IGL02582:Ptprq	APN	10	107,479,860 (GRCm39)	missense	probably benign	0.00
IGL02708:Ptprq	APN	10	107,488,561 (GRCm39)	missense	probably damaging	1.00
IGL02894:Ptprq	APN	10	107,503,285 (GRCm39)	missense	probably benign
IGL02903:Ptprq	APN	10	107,502,447 (GRCm39)	missense	possibly damaging	0.51
IGL02951:Ptprq	APN	10	107,503,321 (GRCm39)	missense	probably benign	0.03
IGL02982:Ptprq	APN	10	107,422,545 (GRCm39)	missense	probably damaging	1.00
IGL03000:Ptprq	APN	10	107,378,518 (GRCm39)	missense	probably damaging	1.00
IGL03024:Ptprq	APN	10	107,521,427 (GRCm39)	missense	possibly damaging	0.69
IGL03240:Ptprq	APN	10	107,524,368 (GRCm39)	missense	probably benign
P0043:Ptprq	UTSW	10	107,416,086 (GRCm39)	missense	probably benign	0.03
PIT4812001:Ptprq	UTSW	10	107,502,428 (GRCm39)	missense	probably damaging	1.00
R0200:Ptprq	UTSW	10	107,521,018 (GRCm39)	missense	probably benign
R0268:Ptprq	UTSW	10	107,541,409 (GRCm39)	missense	probably benign
R0276:Ptprq	UTSW	10	107,378,596 (GRCm39)	critical splice acceptor site	probably null
R0279:Ptprq	UTSW	10	107,444,278 (GRCm39)	missense	probably damaging	0.96
R0335:Ptprq	UTSW	10	107,544,589 (GRCm39)	missense	probably benign
R0344:Ptprq	UTSW	10	107,541,443 (GRCm39)	missense	probably benign
R0357:Ptprq	UTSW	10	107,522,060 (GRCm39)	splice site	probably benign
R0454:Ptprq	UTSW	10	107,418,391 (GRCm39)	nonsense	probably null
R0479:Ptprq	UTSW	10	107,479,855 (GRCm39)	nonsense	probably null
R0491:Ptprq	UTSW	10	107,444,036 (GRCm39)	missense	probably damaging	0.98
R0519:Ptprq	UTSW	10	107,374,781 (GRCm39)	splice site	probably benign
R0523:Ptprq	UTSW	10	107,416,081 (GRCm39)	missense	possibly damaging	0.54
R0553:Ptprq	UTSW	10	107,546,488 (GRCm39)	missense	probably benign	0.33
R0746:Ptprq	UTSW	10	107,353,692 (GRCm39)	missense	probably damaging	1.00
R0755:Ptprq	UTSW	10	107,418,400 (GRCm39)	missense	probably benign	0.09
R1434:Ptprq	UTSW	10	107,422,575 (GRCm39)	missense	probably damaging	1.00
R1445:Ptprq	UTSW	10	107,498,423 (GRCm39)	missense	probably damaging	1.00
R1470:Ptprq	UTSW	10	107,554,435 (GRCm39)	missense	probably damaging	0.97
R1470:Ptprq	UTSW	10	107,554,435 (GRCm39)	missense	probably damaging	0.97
R1558:Ptprq	UTSW	10	107,479,904 (GRCm39)	missense	probably damaging	1.00
R1567:Ptprq	UTSW	10	107,401,748 (GRCm39)	missense	probably benign	0.13
R1711:Ptprq	UTSW	10	107,370,560 (GRCm39)	nonsense	probably null
R1720:Ptprq	UTSW	10	107,522,155 (GRCm39)	missense	probably damaging	1.00
R1746:Ptprq	UTSW	10	107,474,691 (GRCm39)	missense	probably damaging	1.00
R1776:Ptprq	UTSW	10	107,520,950 (GRCm39)	missense	probably damaging	1.00
R1822:Ptprq	UTSW	10	107,554,339 (GRCm39)	missense	probably damaging	1.00
R1872:Ptprq	UTSW	10	107,479,860 (GRCm39)	missense	probably benign	0.19
R1944:Ptprq	UTSW	10	107,418,249 (GRCm39)	missense	probably benign	0.23
R1945:Ptprq	UTSW	10	107,418,249 (GRCm39)	missense	probably benign	0.23
R2006:Ptprq	UTSW	10	107,502,407 (GRCm39)	missense	probably damaging	1.00
R2014:Ptprq	UTSW	10	107,503,283 (GRCm39)	missense	probably damaging	0.96
R2015:Ptprq	UTSW	10	107,503,283 (GRCm39)	missense	probably damaging	0.96
R2097:Ptprq	UTSW	10	107,489,354 (GRCm39)	missense	probably benign	0.05
R2172:Ptprq	UTSW	10	107,426,855 (GRCm39)	nonsense	probably null
R2174:Ptprq	UTSW	10	107,541,414 (GRCm39)	missense	probably damaging	1.00
R2248:Ptprq	UTSW	10	107,478,931 (GRCm39)	splice site	probably null
R2404:Ptprq	UTSW	10	107,522,460 (GRCm39)	missense	probably damaging	1.00
R3423:Ptprq	UTSW	10	107,418,337 (GRCm39)	missense	probably damaging	0.99
R3683:Ptprq	UTSW	10	107,544,489 (GRCm39)	missense	probably benign	0.01
R3875:Ptprq	UTSW	10	107,520,965 (GRCm39)	missense	possibly damaging	0.88
R3945:Ptprq	UTSW	10	107,522,253 (GRCm39)	splice site	probably benign
R3946:Ptprq	UTSW	10	107,522,253 (GRCm39)	splice site	probably benign
R3974:Ptprq	UTSW	10	107,547,923 (GRCm39)	missense	possibly damaging	0.88
R3982:Ptprq	UTSW	10	107,379,257 (GRCm39)	missense	probably damaging	0.99
R4118:Ptprq	UTSW	10	107,547,781 (GRCm39)	missense	probably benign	0.37
R4175:Ptprq	UTSW	10	107,547,778 (GRCm39)	missense	probably benign
R4231:Ptprq	UTSW	10	107,522,144 (GRCm39)	nonsense	probably null
R4356:Ptprq	UTSW	10	107,444,225 (GRCm39)	missense	probably damaging	0.99
R4435:Ptprq	UTSW	10	107,520,916 (GRCm39)	missense	possibly damaging	0.89
R4678:Ptprq	UTSW	10	107,521,043 (GRCm39)	missense	probably benign	0.19
R4679:Ptprq	UTSW	10	107,521,043 (GRCm39)	missense	probably benign	0.19
R4745:Ptprq	UTSW	10	107,360,114 (GRCm39)	missense	probably damaging	1.00
R4771:Ptprq	UTSW	10	107,524,288 (GRCm39)	missense	probably benign
R4778:Ptprq	UTSW	10	107,426,883 (GRCm39)	missense	probably benign	0.15
R4808:Ptprq	UTSW	10	107,554,368 (GRCm39)	missense	probably damaging	1.00
R4809:Ptprq	UTSW	10	107,399,036 (GRCm39)	missense	probably damaging	1.00
R4818:Ptprq	UTSW	10	107,546,442 (GRCm39)	missense	possibly damaging	0.86
R4845:Ptprq	UTSW	10	107,489,393 (GRCm39)	missense	probably benign	0.00
R4901:Ptprq	UTSW	10	107,524,275 (GRCm39)	missense	probably benign	0.01
R4942:Ptprq	UTSW	10	107,524,290 (GRCm39)	missense	probably benign	0.01
R4946:Ptprq	UTSW	10	107,361,595 (GRCm39)	missense	probably benign
R4959:Ptprq	UTSW	10	107,522,416 (GRCm39)	missense	probably damaging	1.00
R4973:Ptprq	UTSW	10	107,522,416 (GRCm39)	missense	probably damaging	1.00
R5007:Ptprq	UTSW	10	107,444,137 (GRCm39)	missense	probably benign	0.00
R5053:Ptprq	UTSW	10	107,399,063 (GRCm39)	missense	probably damaging	1.00
R5055:Ptprq	UTSW	10	107,370,540 (GRCm39)	missense	probably benign	0.37
R5090:Ptprq	UTSW	10	107,361,950 (GRCm39)	missense	probably damaging	1.00
R5158:Ptprq	UTSW	10	107,370,565 (GRCm39)	missense	probably damaging	1.00
R5163:Ptprq	UTSW	10	107,360,192 (GRCm39)	missense	probably damaging	1.00
R5222:Ptprq	UTSW	10	107,498,425 (GRCm39)	missense	probably damaging	0.96
R5244:Ptprq	UTSW	10	107,422,556 (GRCm39)	missense	possibly damaging	0.62
R5249:Ptprq	UTSW	10	107,535,496 (GRCm39)	missense	probably damaging	0.99
R5503:Ptprq	UTSW	10	107,524,189 (GRCm39)	splice site	probably null
R5508:Ptprq	UTSW	10	107,522,092 (GRCm39)	missense	probably benign	0.00
R5601:Ptprq	UTSW	10	107,444,291 (GRCm39)	missense	probably benign
R5722:Ptprq	UTSW	10	107,522,226 (GRCm39)	missense	possibly damaging	0.72
R5819:Ptprq	UTSW	10	107,555,744 (GRCm39)	start gained	probably benign
R5862:Ptprq	UTSW	10	107,401,739 (GRCm39)	missense	probably benign	0.02
R5891:Ptprq	UTSW	10	107,412,756 (GRCm39)	missense	possibly damaging	0.94
R5916:Ptprq	UTSW	10	107,359,374 (GRCm39)	missense	probably damaging	1.00
R6054:Ptprq	UTSW	10	107,418,219 (GRCm39)	missense	probably damaging	1.00
R6058:Ptprq	UTSW	10	107,471,135 (GRCm39)	missense	probably benign	0.00
R6075:Ptprq	UTSW	10	107,361,621 (GRCm39)	missense	probably damaging	1.00
R6101:Ptprq	UTSW	10	107,416,127 (GRCm39)	missense	possibly damaging	0.93
R6189:Ptprq	UTSW	10	107,353,748 (GRCm39)	missense	probably damaging	1.00
R6235:Ptprq	UTSW	10	107,471,199 (GRCm39)	missense	possibly damaging	0.61
R6351:Ptprq	UTSW	10	107,544,529 (GRCm39)	missense	probably damaging	0.99
R6394:Ptprq	UTSW	10	107,478,804 (GRCm39)	nonsense	probably null
R6449:Ptprq	UTSW	10	107,541,444 (GRCm39)	missense	probably benign	0.00
R6526:Ptprq	UTSW	10	107,378,514 (GRCm39)	nonsense	probably null
R6544:Ptprq	UTSW	10	107,444,102 (GRCm39)	missense	probably damaging	1.00
R6609:Ptprq	UTSW	10	107,408,829 (GRCm39)	missense	probably damaging	0.99
R6862:Ptprq	UTSW	10	107,522,086 (GRCm39)	missense	probably damaging	0.96
R6874:Ptprq	UTSW	10	107,554,460 (GRCm39)	missense	possibly damaging	0.80
R6892:Ptprq	UTSW	10	107,411,865 (GRCm39)	missense	probably benign	0.00
R7082:Ptprq	UTSW	10	107,544,591 (GRCm39)	missense	probably benign	0.10
R7210:Ptprq	UTSW	10	107,521,032 (GRCm39)	missense	probably damaging	1.00
R7253:Ptprq	UTSW	10	107,444,134 (GRCm39)	missense	probably benign	0.30
R7293:Ptprq	UTSW	10	107,471,367 (GRCm39)	nonsense	probably null
R7445:Ptprq	UTSW	10	107,426,820 (GRCm39)	missense	probably damaging	1.00
R7632:Ptprq	UTSW	10	107,547,783 (GRCm39)	missense	probably benign	0.32
R7685:Ptprq	UTSW	10	107,479,839 (GRCm39)	missense	probably damaging	1.00
R7703:Ptprq	UTSW	10	107,480,007 (GRCm39)	missense	probably benign	0.01
R7774:Ptprq	UTSW	10	107,479,530 (GRCm39)	missense	probably damaging	0.96
R7897:Ptprq	UTSW	10	107,546,484 (GRCm39)	missense	probably benign	0.21
R7936:Ptprq	UTSW	10	107,488,572 (GRCm39)	missense	probably damaging	1.00
R7983:Ptprq	UTSW	10	107,444,272 (GRCm39)	nonsense	probably null
R8023:Ptprq	UTSW	10	107,488,477 (GRCm39)	nonsense	probably null
R8071:Ptprq	UTSW	10	107,479,896 (GRCm39)	missense	possibly damaging	0.62
R8084:Ptprq	UTSW	10	107,444,294 (GRCm39)	missense	probably benign
R8086:Ptprq	UTSW	10	107,482,500 (GRCm39)	nonsense	probably null
R8169:Ptprq	UTSW	10	107,418,351 (GRCm39)	missense	probably damaging	1.00
R8223:Ptprq	UTSW	10	107,535,499 (GRCm39)	missense	probably benign	0.00
R8235:Ptprq	UTSW	10	107,541,351 (GRCm39)	missense	probably benign	0.32
R8235:Ptprq	UTSW	10	107,418,402 (GRCm39)	missense	probably damaging	1.00
R8278:Ptprq	UTSW	10	107,522,239 (GRCm39)	missense	possibly damaging	0.87
R8710:Ptprq	UTSW	10	107,411,919 (GRCm39)	missense	possibly damaging	0.67
R8828:Ptprq	UTSW	10	107,482,513 (GRCm39)	missense	probably benign
R8830:Ptprq	UTSW	10	107,422,556 (GRCm39)	missense	possibly damaging	0.62
R8869:Ptprq	UTSW	10	107,535,469 (GRCm39)	missense	probably damaging	1.00
R9012:Ptprq	UTSW	10	107,489,411 (GRCm39)	missense	probably benign	0.09
R9072:Ptprq	UTSW	10	107,401,736 (GRCm39)	missense
R9153:Ptprq	UTSW	10	107,416,126 (GRCm39)	missense	probably damaging	0.98
R9202:Ptprq	UTSW	10	107,522,416 (GRCm39)	missense	probably damaging	1.00
R9252:Ptprq	UTSW	10	107,522,247 (GRCm39)	missense	probably benign	0.12
R9306:Ptprq	UTSW	10	107,422,599 (GRCm39)	missense	probably benign	0.00
R9492:Ptprq	UTSW	10	107,478,813 (GRCm39)	missense	probably damaging	1.00
R9519:Ptprq	UTSW	10	107,520,961 (GRCm39)	missense	probably damaging	1.00
R9581:Ptprq	UTSW	10	107,547,771 (GRCm39)	missense	possibly damaging	0.53
R9593:Ptprq	UTSW	10	107,524,254 (GRCm39)	missense	possibly damaging	0.92
R9621:Ptprq	UTSW	10	107,378,523 (GRCm39)	missense	probably damaging	1.00
R9732:Ptprq	UTSW	10	107,412,767 (GRCm39)	missense	probably damaging	1.00
R9743:Ptprq	UTSW	10	107,520,982 (GRCm39)	missense	probably damaging	1.00
R9771:Ptprq	UTSW	10	107,521,085 (GRCm39)	missense	probably damaging	0.99
R9788:Ptprq	UTSW	10	107,401,751 (GRCm39)	missense	probably benign	0.24
Z1088:Ptprq	UTSW	10	107,535,533 (GRCm39)	missense	possibly damaging	0.56
Z1176:Ptprq	UTSW	10	107,361,931 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AAATGGAGTAGATGTTCCACCC -3'
(R):5'- ATTCTAGAAGGAGGTGACCTGAAC -3'

Sequencing Primer
(F):5'- GGAGTAGATGTTCCACCCTCCATATG -3'
(R):5'- TCTCAGGGTACTAAAATCGGC -3'

Posted On

2015-06-12