Mutagenetix > Incidental Mutation

Incidental Mutation 'R4161:Vmn1r221'

321534

Institutional Source

Beutler Lab

Gene Symbol

Vmn1r221

Ensembl Gene

ENSMUSG00000082316

Gene Name

vomeronasal 1 receptor 221

Synonyms

Gm11329

MMRRC Submission

041004-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.133) question?

Stock #

R4161 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

23401543-23402481 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

G to A at 23402176 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

A0A494B935

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000122275

Coding Region Coverage

1x: 99.2%
3x: 98.7%
10x: 97.4%
20x: 95.7%

Validation Efficiency

95% (39/41)

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ackr2	A	G	9: 121,738,588 (GRCm39)	Y321C	probably benign	Het
Angptl3	T	C	4: 98,919,728 (GRCm39)	S163P	probably damaging	Het
Ankle2	T	C	5: 110,382,234 (GRCm39)	M70T	probably benign	Het
Ankrd1	T	A	19: 36,095,273 (GRCm39)	K138N	probably damaging	Het
Ano8	A	T	8: 71,935,281 (GRCm39)	I339N	probably damaging	Het
Bltp3a	A	G	17: 28,103,061 (GRCm39)	Y365C	probably damaging	Het
Cxcl2	A	T	5: 91,051,881 (GRCm39)		probably null	Het
Exosc3	T	C	4: 45,320,619 (GRCm39)		probably benign	Het
Fads2b	C	A	2: 85,348,853 (GRCm39)	K86N	probably damaging	Het
Fat1	G	A	8: 45,489,824 (GRCm39)	A3579T	probably benign	Het
Fat4	G	A	3: 38,996,958 (GRCm39)	V1726I	possibly damaging	Het
Grm7	A	G	6: 111,230,981 (GRCm39)	N468S	probably damaging	Het
Hmgcll1	A	T	9: 75,982,198 (GRCm39)		probably benign	Het
Igkv3-12	T	A	6: 70,495,542 (GRCm39)	V23E	probably benign	Het
Irx6	T	C	8: 93,402,919 (GRCm39)	C95R	possibly damaging	Het
Kif16b	G	A	2: 142,549,324 (GRCm39)	H1064Y	probably benign	Het
Lrrc45	A	T	11: 120,609,272 (GRCm39)	D377V	possibly damaging	Het
Oasl1	A	G	5: 115,075,073 (GRCm39)	K378E	possibly damaging	Het
Pds5a	T	C	5: 65,821,839 (GRCm39)	T120A	possibly damaging	Het
Phf8-ps	G	A	17: 33,285,023 (GRCm39)	T593I	probably benign	Het
Plec	T	C	15: 76,063,851 (GRCm39)	E2141G	possibly damaging	Het
Pou6f1	A	G	15: 100,478,724 (GRCm39)	S395P	probably damaging	Het
Prss12	A	T	3: 123,279,176 (GRCm39)	K418*	probably null	Het
Rtn3	G	A	19: 7,460,444 (GRCm39)	A2V	probably benign	Het
Rubcnl	A	G	14: 75,281,898 (GRCm39)	T452A	possibly damaging	Het
Sdk1	A	G	5: 142,100,154 (GRCm39)	I1395V	probably benign	Het
Senp7	C	A	16: 55,973,832 (GRCm39)	P351Q	possibly damaging	Het
Slco1a7	T	C	6: 141,654,322 (GRCm39)	K647E	probably benign	Het
Spred3	A	G	7: 28,861,210 (GRCm39)	L323P	probably damaging	Het
Srprb	A	G	9: 103,078,529 (GRCm39)	F67S	possibly damaging	Het
Tk2	T	C	8: 104,965,465 (GRCm39)	S101G	probably benign	Het
Tnxb	A	G	17: 34,930,491 (GRCm39)	T2059A	probably damaging	Het
Trpm7	A	G	2: 126,658,751 (GRCm39)	L1135P	probably damaging	Het
Ush2a	G	A	1: 188,460,907 (GRCm39)	V2723M	probably damaging	Het
Usp38	C	T	8: 81,719,967 (GRCm39)	A421T	probably damaging	Het
Vcan	G	T	13: 89,833,277 (GRCm39)	N3058K	probably damaging	Het
Vps11	C	G	9: 44,267,017 (GRCm39)	G406A	probably damaging	Het
Wnk2	C	T	13: 49,244,313 (GRCm39)	D508N	probably damaging	Het
Zbtb10	T	C	3: 9,345,356 (GRCm39)	S707P	probably damaging	Het

Other mutations in Vmn1r221

Allele	Source	Chr	Coord	Type	Predicted Effect
R4763:Vmn1r221	UTSW	13	23,401,958 (GRCm39)	exon	noncoding transcript
R5244:Vmn1r221	UTSW	13	23,401,808 (GRCm39)	exon	noncoding transcript
R5919:Vmn1r221	UTSW	13	23,401,466 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- TCCATTCCATCACAAGTACAGGTC -3'
(R):5'- AAAGTTGCATAACCAAGGGTCAC -3'

Sequencing Primer
(F):5'- CAGGTCTGAATATGTCACAGCTTAGC -3'
(R):5'- GGGTCACAAATTCTAGAGTATTTGCC -3'

Posted On

2015-06-12